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The map label for this gene is appB [H]

Identifier: 239617882

GI number: 239617882

Start: 1619167

End: 1620138

Strand: Reverse

Name: appB [H]

Synonym: Kole_1510

Alternate gene names: 239617882

Gene position: 1620138-1619167 (Counterclockwise)

Preceding gene: 239617883

Following gene: 239617881

Centisome position: 70.38

GC content: 43.93

Gene sequence:

>972_bases
GTGCTCAGATATATACTTAGAAGACTTATACTCGCTGTACCGGTTTTGTTAGGTGTTTCCATCCTTTCGTTCATAATAAT
CTCTTTAGCGCCTGGTGACTTTCTCGATAACTACAGGCTCAATCCTTCTATAAGTGCGGAGCAGGTAAAACTTCTTGAAA
AACAGTTTGGTTTTGATAAACCAATCATCGTTCAATACTTCAAATGGTTAGGACAGGTTTTAAAAGGCAATTTCGGTTAT
TCATTCGTGTATCATGTTCCCGTTTTTAGTATCATCTGGAGAAGATTGGGCGCAACACTCCTCTTAAGTATCTCGACGAT
GATATTTATATGGGGAATTGCCATTCCTCTTGGGATTTATTCAGCGCTCCATCAATATTCCTTCAATGATCAGCTCTTTT
CATTCCTGGCGTTCATTGGTATTTCGATCCCTAATTTCTTCTTCGCTCTTCTATGGTTGTACATGTCCGCAAAGACCGGT
TGGTTCCCGATCGGTGGGATCATATCCAATAATTACGACCAGTTCACATGGTGGCAAAAGATTCTCGATTATCTATGGCA
CGTTATCGGTCCGGTTGTAACCCTTGGAACCTCTGGACTTGCTGGATTAATGAGACAGATGAGGGGACAGCTTCTCGACC
AGCTGCGGCAGGACTACGTTCTCTTCGCCAGAGCCAAGGGTATGCCTGAGGATAATGTCATCTACAAACATGCGGTTAGA
AACGCTATAAACCCGATAGTCACTATGTTTGGATACGCACTCGCAGGGTTGCTTGGTGGTGCTGTCCTTACAGAAACCGT
TTTTGGCTGGCCTGGAATGGGTAGGTTAGTTATAGAAGCCTTGACTGCTCAGGACCTTTTCATGGTCATGGCTTCTCTAT
TACTCAGTTCGCTGTTGCTGATAGCTGGTAACCTGGTTGCAGACCTTCTCCTTGCCTGGGTAGATCCAAGAATCAGATTC
AGATTGAGATAG

Upstream 100 bases:

>100_bases
TCTGGAAAGAAGGGGAATAATCCACGGGGGTGACCTCGTGTTTGCGGGAGGGTCATCCCTCCCGCTTTCATTGTCTTTAC
TGGTTTAAGGAGGGAAGAAG

Downstream 100 bases:

>100_bases
TCAGGAGTGATGTGGCCTTGAAAAAACAAAAAGCAGTTATAAAAACAGAAGATGTAAAAAAAGATGATTTGTTCGAAGTT
GAATACATGAACCGCTGGCA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MLRYILRRLILAVPVLLGVSILSFIIISLAPGDFLDNYRLNPSISAEQVKLLEKQFGFDKPIIVQYFKWLGQVLKGNFGY
SFVYHVPVFSIIWRRLGATLLLSISTMIFIWGIAIPLGIYSALHQYSFNDQLFSFLAFIGISIPNFFFALLWLYMSAKTG
WFPIGGIISNNYDQFTWWQKILDYLWHVIGPVVTLGTSGLAGLMRQMRGQLLDQLRQDYVLFARAKGMPEDNVIYKHAVR
NAINPIVTMFGYALAGLLGGAVLTETVFGWPGMGRLVIEALTAQDLFMVMASLLLSSLLLIAGNLVADLLLAWVDPRIRF
RLR

Sequences:

>Translated_323_residues
MLRYILRRLILAVPVLLGVSILSFIIISLAPGDFLDNYRLNPSISAEQVKLLEKQFGFDKPIIVQYFKWLGQVLKGNFGY
SFVYHVPVFSIIWRRLGATLLLSISTMIFIWGIAIPLGIYSALHQYSFNDQLFSFLAFIGISIPNFFFALLWLYMSAKTG
WFPIGGIISNNYDQFTWWQKILDYLWHVIGPVVTLGTSGLAGLMRQMRGQLLDQLRQDYVLFARAKGMPEDNVIYKHAVR
NAINPIVTMFGYALAGLLGGAVLTETVFGWPGMGRLVIEALTAQDLFMVMASLLLSSLLLIAGNLVADLLLAWVDPRIRF
RLR
>Mature_323_residues
MLRYILRRLILAVPVLLGVSILSFIIISLAPGDFLDNYRLNPSISAEQVKLLEKQFGFDKPIIVQYFKWLGQVLKGNFGY
SFVYHVPVFSIIWRRLGATLLLSISTMIFIWGIAIPLGIYSALHQYSFNDQLFSFLAFIGISIPNFFFALLWLYMSAKTG
WFPIGGIISNNYDQFTWWQKILDYLWHVIGPVVTLGTSGLAGLMRQMRGQLLDQLRQDYVLFARAKGMPEDNVIYKHAVR
NAINPIVTMFGYALAGLLGGAVLTETVFGWPGMGRLVIEALTAQDLFMVMASLLLSSLLLIAGNLVADLLLAWVDPRIRF
RLR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=35.9882005899705, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787053, Length=324, Percent_Identity=36.1111111111111, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1789888, Length=322, Percent_Identity=34.7826086956522, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788504, Length=364, Percent_Identity=31.3186813186813, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787497, Length=323, Percent_Identity=30.6501547987616, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787761, Length=328, Percent_Identity=34.4512195121951, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=28.3018867924528, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36524; Mature: 36524

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYILRRLILAVPVLLGVSILSFIIISLAPGDFLDNYRLNPSISAEQVKLLEKQFGFDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCC
PIIVQYFKWLGQVLKGNFGYSFVYHVPVFSIIWRRLGATLLLSISTMIFIWGIAIPLGIY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALHQYSFNDQLFSFLAFIGISIPNFFFALLWLYMSAKTGWFPIGGIISNNYDQFTWWQK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHCCCCHHHHHHHH
ILDYLWHVIGPVVTLGTSGLAGLMRQMRGQLLDQLRQDYVLFARAKGMPEDNVIYKHAVR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
NAINPIVTMFGYALAGLLGGAVLTETVFGWPGMGRLVIEALTAQDLFMVMASLLLSSLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGNLVADLLLAWVDPRIRFRLR
HHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]