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The map label for this gene is regX3 [H]

Identifier: 239617230

GI number: 239617230

Start: 884594

End: 885274

Strand: Reverse

Name: regX3 [H]

Synonym: Kole_0838

Alternate gene names: 239617230

Gene position: 885274-884594 (Counterclockwise)

Preceding gene: 239617231

Following gene: 239617229

Centisome position: 38.45

GC content: 40.97

Gene sequence:

>681_bases
TTGAAAAAAATATTGCTTGTAGAAGATGATGAGACACTTGCAATGGGAATCAAATATGCTCTAGAACAGGAAGCTTTTCT
TGTGGAGGTTGCAACAGAACTCGAATCAGCAAGAAAGCGTATTGACGAAAAAGACTTCGATCTCATACTCCTGGATGTTA
TGTTGCCGAATGGGAACGGTTTTCAATTGTGCAAGGAAATAAGGACCTATTCGGATTTGCCCATTATTTTCCTCACCGCC
AGGGATGAAGAGGTAAATATAGTCATGGGCCTCGAGCTGGGAGCTGATGACTATATAACTAAACCATTTAAGCTAAAAGA
ACTCGTTGCCAGAATCAGAGCAAATCTCAGAAGGATTGAAGGTAAAAAGACTGTTAACCGATACCTGATTTCAGGTCAGA
TACGTCTCGACATAGTGAATCAGAAACTCATGGTTGAAGATGCTGAACAGCACTTGACTCCGGTAGAATTTAGGCTTTTG
TTTGCCCTTATGGATAACGCTGGACGAATTCTAACCAGAGATCAGCTTTTGGGATATGTCTGGAATACAGAAAGTGATTT
TGTGGATGATAACACTCTTTCCGTTCATATCAGAAAACTCAGAGAAAAAATAGAAGACGATCCCTCAAAGCCAGAGCACA
TACTCACCGTAAGAGGACTCGGATATAGGTGGCGAGAATAA

Upstream 100 bases:

>100_bases
GAAGAGGTTTTTGGTTAAAATTGGATTCCAGTTAAAAGCAATAAAAGAAGGCAGACACAGAAAATAGTGTCTGTCATCTT
TTTAGTTGGGAGGAATGGCT

Downstream 100 bases:

>100_bases
TGGTACAGCTTTTAGATAACAGGGATTTCAGAAGAACACTCTGGTTAATTGTGGGTTGTGTAGTTTTTTTTGCTTTTATT
GTTAGCTTCTTCTGCTTTTT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKKILLVEDDETLAMGIKYALEQEAFLVEVATELESARKRIDEKDFDLILLDVMLPNGNGFQLCKEIRTYSDLPIIFLTA
RDEEVNIVMGLELGADDYITKPFKLKELVARIRANLRRIEGKKTVNRYLISGQIRLDIVNQKLMVEDAEQHLTPVEFRLL
FALMDNAGRILTRDQLLGYVWNTESDFVDDNTLSVHIRKLREKIEDDPSKPEHILTVRGLGYRWRE

Sequences:

>Translated_226_residues
MKKILLVEDDETLAMGIKYALEQEAFLVEVATELESARKRIDEKDFDLILLDVMLPNGNGFQLCKEIRTYSDLPIIFLTA
RDEEVNIVMGLELGADDYITKPFKLKELVARIRANLRRIEGKKTVNRYLISGQIRLDIVNQKLMVEDAEQHLTPVEFRLL
FALMDNAGRILTRDQLLGYVWNTESDFVDDNTLSVHIRKLREKIEDDPSKPEHILTVRGLGYRWRE
>Mature_226_residues
MKKILLVEDDETLAMGIKYALEQEAFLVEVATELESARKRIDEKDFDLILLDVMLPNGNGFQLCKEIRTYSDLPIIFLTA
RDEEVNIVMGLELGADDYITKPFKLKELVARIRANLRRIEGKKTVNRYLISGQIRLDIVNQKLMVEDAEQHLTPVEFRLL
FALMDNAGRILTRDQLLGYVWNTESDFVDDNTLSVHIRKLREKIEDDPSKPEHILTVRGLGYRWRE

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=42.0353982300885, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=36.6071428571429, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=37.6106194690265, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=38.7665198237885, Blast_Score=146, Evalue=9e-37,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=35.5855855855856, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=37.5545851528384, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=36.3636363636364, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=38.1165919282511, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.2941176470588, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=36.8888888888889, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.0396475770925, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=38.4279475982533, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=31.8965517241379, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=30.316742081448, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26249; Mature: 26249

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLVEDDETLAMGIKYALEQEAFLVEVATELESARKRIDEKDFDLILLDVMLPNGNG
CCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCH
FQLCKEIRTYSDLPIIFLTARDEEVNIVMGLELGADDYITKPFKLKELVARIRANLRRIE
HHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
GKKTVNRYLISGQIRLDIVNQKLMVEDAEQHLTPVEFRLLFALMDNAGRILTRDQLLGYV
CHHHHHHEEEECEEEEEEECCCCEEECHHHCCCHHHHHHHHHHHCCCCCEEEHHHHEEEE
WNTESDFVDDNTLSVHIRKLREKIEDDPSKPEHILTVRGLGYRWRE
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MKKILLVEDDETLAMGIKYALEQEAFLVEVATELESARKRIDEKDFDLILLDVMLPNGNG
CCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCH
FQLCKEIRTYSDLPIIFLTARDEEVNIVMGLELGADDYITKPFKLKELVARIRANLRRIE
HHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
GKKTVNRYLISGQIRLDIVNQKLMVEDAEQHLTPVEFRLLFALMDNAGRILTRDQLLGYV
CHHHHHHEEEECEEEEEEECCCCEEECHHHCCCHHHHHHHHHHHCCCCCEEEHHHHEEEE
WNTESDFVDDNTLSVHIRKLREKIEDDPSKPEHILTVRGLGYRWRE
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA