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The map label for this gene is senX3 [H]

Identifier: 239617229

GI number: 239617229

Start: 883338

End: 884594

Strand: Reverse

Name: senX3 [H]

Synonym: Kole_0837

Alternate gene names: 239617229

Gene position: 884594-883338 (Counterclockwise)

Preceding gene: 239617230

Following gene: 239617228

Centisome position: 38.43

GC content: 38.03

Gene sequence:

>1257_bases
ATGGTACAGCTTTTAGATAACAGGGATTTCAGAAGAACACTCTGGTTAATTGTGGGTTGTGTAGTTTTTTTTGCTTTTAT
TGTTAGCTTCTTCTGCTTTTTTAGTTATAAGAGACTTTATGCTGGGGTAGAGAAAGAAAGGCTTGAGTTACTGGGAAGAC
TTACAGAAGAAATACCAGAAATAAAAGGAAAAGAAGATTTATTCTTTGAAAAAGGGTCAGAAAGGTACTATCAAAAGGGT
TTATCCATAGCGATAAAATATGGTTATGCCAAAGGGAATTTTCTAGGTAATGCCGCATTCAATATCTCTTTCCTCCGATC
TGTTCTGTTTTCTCTATGTGTTTTGGTATGTAGTGCATTTTTTATTTTAATCATATTTTCCGGGCAGCTTTCGAAAATTT
ATAAGACACTTCGTGAGTACTCACTTGGTGCCGATGCTGTGATGAATGAAGATTACGACTATTCCTTTGATTCTCTGGAG
GAAGGAGATCTTGCTATTCTTGGTACGCAGCTTGATCAAATGGTAAGAAGGCTGAAATTGACAGTAGAAGCTTTAAATGC
AGAAAAAGAAAAGCTAAGAATCTTCATTTCTCAGATGACGCATCAACTAAAGACGCCACTGGCTTCTATGAAGCTCATGA
TAGAACTTTCGCTTTCGGATAACATCGATCCGGAAAAGAAACGTGAGTTTTTAGAGAGAAGTCTTGCAGAACAAAACAAA
ATGGAGTGGCTCATACAAACCCTTCTGGATATATCCCGGTTGGAAATAGGGAAAGTAAAGCTTAACATGAAGGATATCGA
ACTTCCTGAACTCATAAAACAAACAGTACAGGTACTGGAGCCCAGGTGGAGGAAAAAGAATCACCAGATAATTTTTAGCT
TACCCGAGTCTTTCAGGTTTCAATGTGACCCCAACTGGTTTGGCCAGGCTCTTGAAAACATCTTAAAAAACGCCATCGAT
TACACGCCAGAAAACGGGAGAATAGAAATCAAATTAGTTGAAAATGATGCATACATGAAACTTATCTTCAAGGACAATGG
AATCGGTATAGAGCCTGAAGATTTGCCCTTCATTTTCGATAAATTCTATCGCGGAAGAAAAGCTTTAATTATAAATCGAA
ATGGAACGGGAATAGGATTAACACTCTCAAAGGCAATCATTGAGCGCCACGACGGAGAAATACGTATTAAATCTATTCCA
GGCACCGGCTCAGAGTTCATTCTGGAATTTCCCCGAGATCACCTTAAGAAATCTTAA

Upstream 100 bases:

>100_bases
CCGTTCATATCAGAAAACTCAGAGAAAAAATAGAAGACGATCCCTCAAAGCCAGAGCACATACTCACCGTAAGAGGACTC
GGATATAGGTGGCGAGAATA

Downstream 100 bases:

>100_bases
TCTTTTACTTAAGCCAAACTGAAGGTACGCTCCTCAAAATATATGTACGAATGTCGAAGAGGAGGAATCGTTGTGCATAT
TCTAAAAACGATCAATCTTG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MVQLLDNRDFRRTLWLIVGCVVFFAFIVSFFCFFSYKRLYAGVEKERLELLGRLTEEIPEIKGKEDLFFEKGSERYYQKG
LSIAIKYGYAKGNFLGNAAFNISFLRSVLFSLCVLVCSAFFILIIFSGQLSKIYKTLREYSLGADAVMNEDYDYSFDSLE
EGDLAILGTQLDQMVRRLKLTVEALNAEKEKLRIFISQMTHQLKTPLASMKLMIELSLSDNIDPEKKREFLERSLAEQNK
MEWLIQTLLDISRLEIGKVKLNMKDIELPELIKQTVQVLEPRWRKKNHQIIFSLPESFRFQCDPNWFGQALENILKNAID
YTPENGRIEIKLVENDAYMKLIFKDNGIGIEPEDLPFIFDKFYRGRKALIINRNGTGIGLTLSKAIIERHDGEIRIKSIP
GTGSEFILEFPRDHLKKS

Sequences:

>Translated_418_residues
MVQLLDNRDFRRTLWLIVGCVVFFAFIVSFFCFFSYKRLYAGVEKERLELLGRLTEEIPEIKGKEDLFFEKGSERYYQKG
LSIAIKYGYAKGNFLGNAAFNISFLRSVLFSLCVLVCSAFFILIIFSGQLSKIYKTLREYSLGADAVMNEDYDYSFDSLE
EGDLAILGTQLDQMVRRLKLTVEALNAEKEKLRIFISQMTHQLKTPLASMKLMIELSLSDNIDPEKKREFLERSLAEQNK
MEWLIQTLLDISRLEIGKVKLNMKDIELPELIKQTVQVLEPRWRKKNHQIIFSLPESFRFQCDPNWFGQALENILKNAID
YTPENGRIEIKLVENDAYMKLIFKDNGIGIEPEDLPFIFDKFYRGRKALIINRNGTGIGLTLSKAIIERHDGEIRIKSIP
GTGSEFILEFPRDHLKKS
>Mature_418_residues
MVQLLDNRDFRRTLWLIVGCVVFFAFIVSFFCFFSYKRLYAGVEKERLELLGRLTEEIPEIKGKEDLFFEKGSERYYQKG
LSIAIKYGYAKGNFLGNAAFNISFLRSVLFSLCVLVCSAFFILIIFSGQLSKIYKTLREYSLGADAVMNEDYDYSFDSLE
EGDLAILGTQLDQMVRRLKLTVEALNAEKEKLRIFISQMTHQLKTPLASMKLMIELSLSDNIDPEKKREFLERSLAEQNK
MEWLIQTLLDISRLEIGKVKLNMKDIELPELIKQTVQVLEPRWRKKNHQIIFSLPESFRFQCDPNWFGQALENILKNAID
YTPENGRIEIKLVENDAYMKLIFKDNGIGIEPEDLPFIFDKFYRGRKALIINRNGTGIGLTLSKAIIERHDGEIRIKSIP
GTGSEFILEFPRDHLKKS

Specific function: Probably forms part of a two-component regulatory system senX3/regX3. Phosphorylates regX3 (Probable) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=26.7206477732794, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=24.7747747747748, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=22.9299363057325, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=23.8095238095238, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=26.0869565217391, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=29.1497975708502, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=27.8260869565217, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789149, Length=260, Percent_Identity=28.4615384615385, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=25.2, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=281, Percent_Identity=27.0462633451957, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=248, Percent_Identity=26.6129032258064, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788279, Length=310, Percent_Identity=25.1612903225806, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=201, Percent_Identity=25.8706467661692, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=23.8297872340426, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787374, Length=245, Percent_Identity=23.6734693877551, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790551, Length=228, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48506; Mature: 48506

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLLDNRDFRRTLWLIVGCVVFFAFIVSFFCFFSYKRLYAGVEKERLELLGRLTEEIPE
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
IKGKEDLFFEKGSERYYQKGLSIAIKYGYAKGNFLGNAAFNISFLRSVLFSLCVLVCSAF
CCCCCCHHHCCCCHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FILIIFSGQLSKIYKTLREYSLGADAVMNEDYDYSFDSLEEGDLAILGTQLDQMVRRLKL
HHHHHHCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
TVEALNAEKEKLRIFISQMTHQLKTPLASMKLMIELSLSDNIDPEKKREFLERSLAEQNK
HHHHHCCHHHHHHHHHHHHHHHHHCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MEWLIQTLLDISRLEIGKVKLNMKDIELPELIKQTVQVLEPRWRKKNHQIIFSLPESFRF
HHHHHHHHHHHHHCEECEEEECCCCCCHHHHHHHHHHHHCHHHCCCCCEEEEECCCCCCE
QCDPNWFGQALENILKNAIDYTPENGRIEIKLVENDAYMKLIFKDNGIGIEPEDLPFIFD
ECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCHHHHH
KFYRGRKALIINRNGTGIGLTLSKAIIERHDGEIRIKSIPGTGSEFILEFPRDHLKKS
HHHCCCEEEEEECCCCEEEHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCHHHCCCC
>Mature Secondary Structure
MVQLLDNRDFRRTLWLIVGCVVFFAFIVSFFCFFSYKRLYAGVEKERLELLGRLTEEIPE
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
IKGKEDLFFEKGSERYYQKGLSIAIKYGYAKGNFLGNAAFNISFLRSVLFSLCVLVCSAF
CCCCCCHHHCCCCHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FILIIFSGQLSKIYKTLREYSLGADAVMNEDYDYSFDSLEEGDLAILGTQLDQMVRRLKL
HHHHHHCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
TVEALNAEKEKLRIFISQMTHQLKTPLASMKLMIELSLSDNIDPEKKREFLERSLAEQNK
HHHHHCCHHHHHHHHHHHHHHHHHCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MEWLIQTLLDISRLEIGKVKLNMKDIELPELIKQTVQVLEPRWRKKNHQIIFSLPESFRF
HHHHHHHHHHHHHCEECEEEECCCCCCHHHHHHHHHHHHCHHHCCCCCEEEEECCCCCCE
QCDPNWFGQALENILKNAIDYTPENGRIEIKLVENDAYMKLIFKDNGIGIEPEDLPFIFD
ECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCHHHHH
KFYRGRKALIINRNGTGIGLTLSKAIIERHDGEIRIKSIPGTGSEFILEFPRDHLKKS
HHHCCCEEEEEECCCCEEEHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9426136; 12788972 [H]