Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 239617086

GI number: 239617086

Start: 740712

End: 741731

Strand: Reverse

Name: glmS [H]

Synonym: Kole_0688

Alternate gene names: 239617086

Gene position: 741731-740712 (Counterclockwise)

Preceding gene: 239617087

Following gene: 239617085

Centisome position: 32.22

GC content: 41.76

Gene sequence:

>1020_bases
ATGCAAACACTCGATGAAATAAGACAGCAGCCAGAGAAGCATCGATTACTCAGTGAAAAGTATCCAGAAGTAATTCAGAA
ACTAAAAGATTTAATTCTGGATAAAAAGCCGAAAGAGATCAACTTTGTGGGTTGTGGTTCTTCTTACTATCTTGCGATGG
GGCTTTCCAGACACTTCAACCGTCTGTCTGATGGAGAAATCAGATCGAATTATTACAGTGGTTCCGAGATAATGTTTGGG
CTAAGCAAACTTCCTGCTGATTCACTCCTGATAGGACTTTCACGTTCCGGTGAATCATCTGAAACGATTGGGGCGCTAGA
AAAGGCGAGAGATTATGGAGCCTATATAGCTGCGGTTACCTGCGAACCCGGCAGTACAATGACGCGGGTGGCGGATGTTA
CTGTAGAGATGGATTTTATCGAAGAAAAATCCATAGTCATGACAAAATCATTCACCTCCATGGCTTTTCTTATTTCTGCG
CTGGCAAAAGATCTCTTTTCAAGTGAAAACTTAGAGAGTTATTTGAAAGAGATCCCGGAACTATCTAAAAAGGTGCTTGA
TGATGCGGAAGCTCTTTTTGATAAGTTGAATCCCGGAAAATTTGAGCACTTTGTTTTTCTTGGTTATGATGAGTATTTCA
GTGCGGCAATGGAAGGGGTTATAAAGGTTACCGAGACATCTCTTTCAGATGTTGACTGCTACCAGACATTGGAGTACAGA
CACGGTCCGAAATCGAAGATCAAAGCGAATTCACTGGCGGTCATCCTTGCAAATTCAAAATTGTATGAGGAAGAAGAAAA
AATGGCGCACGAAATCGTGGAACTCGGCGGAACGGTCATCAGTATCGCTTATAGAAAATTTCAAGGAACAAACGGAATCG
AGATTTCATATGAGAAAGATGATTTTGGTGATTGGTTCCTGAGAGTGATTCCTCTGCAATTGATAGGTATTAGGCGCGCA
GTTGCTAAGGGGCTTGATCCTGATAAACCAACACATCTAACGAAGGTTGTGAAATTCTGA

Upstream 100 bases:

>100_bases
TAATGGCATTTGCGGCTGAAGAATCGAGACTGAATAATAAGGTTATAAACATGGAAGAATATCGAAAAGAAAAGCTCTAT
GGATCGGGGAGGTAATAGAC

Downstream 100 bases:

>100_bases
TGAAATCTTATGACTTCTTTCTTGGTGTTGACGGTGGTGGCACAAAAACATTCGCGGTAGTTTATTCTGGCACGGGTGAA
TGTTTGGGGACGGGCCGGGC

Product: Glutamine--fructose-6-phosphate transaminase (isomerizing)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQTLDEIRQQPEKHRLLSEKYPEVIQKLKDLILDKKPKEINFVGCGSSYYLAMGLSRHFNRLSDGEIRSNYYSGSEIMFG
LSKLPADSLLIGLSRSGESSETIGALEKARDYGAYIAAVTCEPGSTMTRVADVTVEMDFIEEKSIVMTKSFTSMAFLISA
LAKDLFSSENLESYLKEIPELSKKVLDDAEALFDKLNPGKFEHFVFLGYDEYFSAAMEGVIKVTETSLSDVDCYQTLEYR
HGPKSKIKANSLAVILANSKLYEEEEKMAHEIVELGGTVISIAYRKFQGTNGIEISYEKDDFGDWFLRVIPLQLIGIRRA
VAKGLDPDKPTHLTKVVKF

Sequences:

>Translated_339_residues
MQTLDEIRQQPEKHRLLSEKYPEVIQKLKDLILDKKPKEINFVGCGSSYYLAMGLSRHFNRLSDGEIRSNYYSGSEIMFG
LSKLPADSLLIGLSRSGESSETIGALEKARDYGAYIAAVTCEPGSTMTRVADVTVEMDFIEEKSIVMTKSFTSMAFLISA
LAKDLFSSENLESYLKEIPELSKKVLDDAEALFDKLNPGKFEHFVFLGYDEYFSAAMEGVIKVTETSLSDVDCYQTLEYR
HGPKSKIKANSLAVILANSKLYEEEEKMAHEIVELGGTVISIAYRKFQGTNGIEISYEKDDFGDWFLRVIPLQLIGIRRA
VAKGLDPDKPTHLTKVVKF
>Mature_339_residues
MQTLDEIRQQPEKHRLLSEKYPEVIQKLKDLILDKKPKEINFVGCGSSYYLAMGLSRHFNRLSDGEIRSNYYSGSEIMFG
LSKLPADSLLIGLSRSGESSETIGALEKARDYGAYIAAVTCEPGSTMTRVADVTVEMDFIEEKSIVMTKSFTSMAFLISA
LAKDLFSSENLESYLKEIPELSKKVLDDAEALFDKLNPGKFEHFVFLGYDEYFSAAMEGVIKVTETSLSDVDCYQTLEYR
HGPKSKIKANSLAVILANSKLYEEEEKMAHEIVELGGTVISIAYRKFQGTNGIEISYEKDDFGDWFLRVIPLQLIGIRRA
VAKGLDPDKPTHLTKVVKF

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=361, Percent_Identity=25.7617728531856, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI205277386, Length=360, Percent_Identity=24.1666666666667, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1790167, Length=324, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17532897, Length=340, Percent_Identity=25, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17532899, Length=340, Percent_Identity=25, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17539970, Length=328, Percent_Identity=23.780487804878, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322745, Length=362, Percent_Identity=25.6906077348066, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323731, Length=267, Percent_Identity=27.7153558052434, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357745, Length=366, Percent_Identity=23.224043715847, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 38087; Mature: 38087

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLDEIRQQPEKHRLLSEKYPEVIQKLKDLILDKKPKEINFVGCGSSYYLAMGLSRHFN
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHC
RLSDGEIRSNYYSGSEIMFGLSKLPADSLLIGLSRSGESSETIGALEKARDYGAYIAAVT
CCCCCCHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEE
CEPGSTMTRVADVTVEMDFIEEKSIVMTKSFTSMAFLISALAKDLFSSENLESYLKEIPE
ECCCCCHHHHHHEEEEEEHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LSKKVLDDAEALFDKLNPGKFEHFVFLGYDEYFSAAMEGVIKVTETSLSDVDCYQTLEYR
HHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
HGPKSKIKANSLAVILANSKLYEEEEKMAHEIVELGGTVISIAYRKFQGTNGIEISYEKD
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEHHHHHHCCCCCEEEEECCC
DFGDWFLRVIPLQLIGIRRAVAKGLDPDKPTHLTKVVKF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MQTLDEIRQQPEKHRLLSEKYPEVIQKLKDLILDKKPKEINFVGCGSSYYLAMGLSRHFN
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHC
RLSDGEIRSNYYSGSEIMFGLSKLPADSLLIGLSRSGESSETIGALEKARDYGAYIAAVT
CCCCCCHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEE
CEPGSTMTRVADVTVEMDFIEEKSIVMTKSFTSMAFLISALAKDLFSSENLESYLKEIPE
ECCCCCHHHHHHEEEEEEHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LSKKVLDDAEALFDKLNPGKFEHFVFLGYDEYFSAAMEGVIKVTETSLSDVDCYQTLEYR
HHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
HGPKSKIKANSLAVILANSKLYEEEEKMAHEIVELGGTVISIAYRKFQGTNGIEISYEKD
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEHHHHHHCCCCCEEEEECCC
DFGDWFLRVIPLQLIGIRRAVAKGLDPDKPTHLTKVVKF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]