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The map label for this gene is atoD [H]

Identifier: 239616997

GI number: 239616997

Start: 645243

End: 645896

Strand: Reverse

Name: atoD [H]

Synonym: Kole_0597

Alternate gene names: 239616997

Gene position: 645896-645243 (Counterclockwise)

Preceding gene: 239616998

Following gene: 239616996

Centisome position: 28.06

GC content: 45.87

Gene sequence:

>654_bases
GTGAAGGTCATCAAAAGTAAGGAAGTGGTTGATTTAATTCCAGAGGGTGCGACTGTGATGATAGGGGGATTTCTTGGTTG
CGGCAGTCCGGAGACTTTGATAGATGAAATAATCAAAGCGAAAAAGGGTGGTCTTACCGTTATAGCCAACGATACAGCGT
TTCCAGACAAAGGAATCGGAAAACTCATCGTTAACAAGCTTGTGAAAAAGGTTATTGCTTCGCATATCGGCACAAACCCT
GAAACCCAGCGGCAAATGATAGAAAAGGAATTGGAAGTAGAACTCATCCCACAGGGGACGCTTGCAGAAAGAGTTCGCGC
CGGTGGAGTTGGACTGGGGGGCATTTTAACTCCAACCGGTGTCGGAACGGTTGTGGAAGAAGGCAAACAGACCATCGAAC
TCGATGGCAAAAAGTATCTGATCGAGCTTCCACTTAGGGCGGATGTTGCGCTTATAAAGGCAAAAAAAGCTGATTATTTT
GGCAATCTCGTTTTCTCTCTCACGGCTAAAAATTTCAATCCTCTCATGGTAATGGCAGGGGATGTTGTCATAGTGGAAGT
GGAGGAAGTTGTTCCTGTAGGTGCTATTCCGCCTGATGAAGTGCACATCCCTGGGGTACTTGTAGATTATATTGTCGTTG
GGGGGTGTAAATGA

Upstream 100 bases:

>100_bases
AACAGCCATTATTATAAAGAGAATCTGAGTTAGTCCGTTGTTCCTGATAAGGATCTAAGTAGTCCTAACCATGACTTGGA
ATCCGAAGGGAGGATCTAAG

Downstream 100 bases:

>100_bases
TGAATCCTAAGGAATTAATAGCAAGGCGTGTGGCACTTGAATTGAAAGATGGAAATCTCGCTAATCTTGGTATAGGCATT
CCAACACTGGTTGCGAATTA

Product: 3-oxoacid CoA-transferase, A subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKVIKSKEVVDLIPEGATVMIGGFLGCGSPETLIDEIIKAKKGGLTVIANDTAFPDKGIGKLIVNKLVKKVIASHIGTNP
ETQRQMIEKELEVELIPQGTLAERVRAGGVGLGGILTPTGVGTVVEEGKQTIELDGKKYLIELPLRADVALIKAKKADYF
GNLVFSLTAKNFNPLMVMAGDVVIVEVEEVVPVGAIPPDEVHIPGVLVDYIVVGGCK

Sequences:

>Translated_217_residues
MKVIKSKEVVDLIPEGATVMIGGFLGCGSPETLIDEIIKAKKGGLTVIANDTAFPDKGIGKLIVNKLVKKVIASHIGTNP
ETQRQMIEKELEVELIPQGTLAERVRAGGVGLGGILTPTGVGTVVEEGKQTIELDGKKYLIELPLRADVALIKAKKADYF
GNLVFSLTAKNFNPLMVMAGDVVIVEVEEVVPVGAIPPDEVHIPGVLVDYIVVGGCK
>Mature_217_residues
MKVIKSKEVVDLIPEGATVMIGGFLGCGSPETLIDEIIKAKKGGLTVIANDTAFPDKGIGKLIVNKLVKKVIASHIGTNP
ETQRQMIEKELEVELIPQGTLAERVRAGGVGLGGILTPTGVGTVVEEGKQTIELDGKKYLIELPLRADVALIKAKKADYF
GNLVFSLTAKNFNPLMVMAGDVVIVEVEEVVPVGAIPPDEVHIPGVLVDYIVVGGCK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=225, Percent_Identity=42.6666666666667, Blast_Score=194, Evalue=7e-50,
Organism=Homo sapiens, GI11545841, Length=225, Percent_Identity=43.1111111111111, Blast_Score=177, Evalue=7e-45,
Organism=Escherichia coli, GI1788551, Length=212, Percent_Identity=55.188679245283, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1787985, Length=240, Percent_Identity=27.5, Blast_Score=81, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17531517, Length=234, Percent_Identity=41.4529914529915, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21358325, Length=225, Percent_Identity=42.6666666666667, Blast_Score=183, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24655794, Length=225, Percent_Identity=42.6666666666667, Blast_Score=183, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 22960; Mature: 22960

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIKSKEVVDLIPEGATVMIGGFLGCGSPETLIDEIIKAKKGGLTVIANDTAFPDKGIG
CCCCCCCCHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHH
KLIVNKLVKKVIASHIGTNPETQRQMIEKELEVELIPQGTLAERVRAGGVGLGGILTPTG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCHHHHHHHCCCCCCCCEECCCC
VGTVVEEGKQTIELDGKKYLIELPLRADVALIKAKKADYFGNLVFSLTAKNFNPLMVMAG
CHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEECCCCHHCCEEEEEECCCCCEEEEEEC
DVVIVEVEEVVPVGAIPPDEVHIPGVLVDYIVVGGCK
CEEEEEEHHCCCCCCCCCCCEECCHHHHHHHHHCCCC
>Mature Secondary Structure
MKVIKSKEVVDLIPEGATVMIGGFLGCGSPETLIDEIIKAKKGGLTVIANDTAFPDKGIG
CCCCCCCCHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHH
KLIVNKLVKKVIASHIGTNPETQRQMIEKELEVELIPQGTLAERVRAGGVGLGGILTPTG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCHHHHHHHCCCCCCCCEECCCC
VGTVVEEGKQTIELDGKKYLIELPLRADVALIKAKKADYFGNLVFSLTAKNFNPLMVMAG
CHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEECCCCHHCCEEEEEECCCCCEEEEEEC
DVVIVEVEEVVPVGAIPPDEVHIPGVLVDYIVVGGCK
CEEEEEEHHCCCCCCCCCCCEECCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]