Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 239616933

GI number: 239616933

Start: 583172

End: 583714

Strand: Reverse

Name: dnaQ [H]

Synonym: Kole_0531

Alternate gene names: 239616933

Gene position: 583714-583172 (Counterclockwise)

Preceding gene: 239616934

Following gene: 239616932

Centisome position: 25.36

GC content: 44.57

Gene sequence:

>543_bases
TTGGAATTTGTTGTCATAGATACCGAAACCACCGGTTCCAGCCCTCATAAAGGGGCAGAGTTGATAGAAATCGCGGGCGT
GGTTGTCAGGGACTGGGAAATAATCTACGAAGAATCCTTCAACGAACTTATAAAACCAAAGAGGCACGTGCCGATCTCCA
TAACCATGATTACAGGCATAAACAACCTGATGCTCGAAGATAAGCTTCCGATAGAAATTGTTCTACCGAGGTTTTATGAT
TTCGTGAGAGATCGCGTTCTTGTGATACAAAATGCTCCCTTTGATCTTTCCTTTCTCGATTATTTCGGGAAGAAAATTGG
AATCGGCGAACTTCCGAATCCTTTTGTGGATACCATCAGCCTTTCGCGCAGCCTTTTTCGTGGCAGACACAATCTTGACA
TTATTCTGGCGCGCCTGGGTATCTTTTGTGAGGATCGGCATCGTGCGCTGGGAGATGCTGTCGCCACTGCAAAAGCGTTC
ATAAAGATGGTGAAGATGATAGGTGTCGAAGAAATTGAGAAGTTTGTTGTGAAAAGGATTTGA

Upstream 100 bases:

>100_bases
GGATTACACACATCAAAGTTTTTACCGGAGGACAGATGCATTGATTTTGGCGTGAAGGTATTTTATTCTCTACTCAAGGA
AGTGAGTAAGGAGGATTGAA

Downstream 100 bases:

>100_bases
TACCGCAATTTTTTTCCACTTCTTCAAAATTGAACACTAATCGGGAATAATTACTCTAAGTTTCTTATTATAGTAAAAAT
ATAGATGCGTTATTTTTTCT

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MEFVVIDTETTGSSPHKGAELIEIAGVVVRDWEIIYEESFNELIKPKRHVPISITMITGINNLMLEDKLPIEIVLPRFYD
FVRDRVLVIQNAPFDLSFLDYFGKKIGIGELPNPFVDTISLSRSLFRGRHNLDIILARLGIFCEDRHRALGDAVATAKAF
IKMVKMIGVEEIEKFVVKRI

Sequences:

>Translated_180_residues
MEFVVIDTETTGSSPHKGAELIEIAGVVVRDWEIIYEESFNELIKPKRHVPISITMITGINNLMLEDKLPIEIVLPRFYD
FVRDRVLVIQNAPFDLSFLDYFGKKIGIGELPNPFVDTISLSRSLFRGRHNLDIILARLGIFCEDRHRALGDAVATAKAF
IKMVKMIGVEEIEKFVVKRI
>Mature_180_residues
MEFVVIDTETTGSSPHKGAELIEIAGVVVRDWEIIYEESFNELIKPKRHVPISITMITGINNLMLEDKLPIEIVLPRFYD
FVRDRVLVIQNAPFDLSFLDYFGKKIGIGELPNPFVDTISLSRSLFRGRHNLDIILARLGIFCEDRHRALGDAVATAKAF
IKMVKMIGVEEIEKFVVKRI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=172, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR000014
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 20515; Mature: 20515

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFVVIDTETTGSSPHKGAELIEIAGVVVRDWEIIYEESFNELIKPKRHVPISITMITGI
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
NNLMLEDKLPIEIVLPRFYDFVRDRVLVIQNAPFDLSFLDYFGKKIGIGELPNPFVDTIS
CHHEECCCCCCEEECHHHHHHHHCEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHH
LSRSLFRGRHNLDIILARLGIFCEDRHRALGDAVATAKAFIKMVKMIGVEEIEKFVVKRI
HHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MEFVVIDTETTGSSPHKGAELIEIAGVVVRDWEIIYEESFNELIKPKRHVPISITMITGI
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
NNLMLEDKLPIEIVLPRFYDFVRDRVLVIQNAPFDLSFLDYFGKKIGIGELPNPFVDTIS
CHHEECCCCCCEEECHHHHHHHHCEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHH
LSRSLFRGRHNLDIILARLGIFCEDRHRALGDAVATAKAFIKMVKMIGVEEIEKFVVKRI
HHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]