Click here to switch to the map view.

The map label for this gene is ftsZ [H]

Identifier: 239616761

GI number: 239616761

Start: 372276

End: 373331

Strand: Direct

Name: ftsZ [H]

Synonym: Kole_0354

Alternate gene names: 239616761

Gene position: 372276-373331 (Clockwise)

Preceding gene: 239616760

Following gene: 239616762

Centisome position: 16.17

GC content: 45.17

Gene sequence:

>1056_bases
ATGAGCTTTGAGATGAGCTACGAAGGAAAAGAAACTGATGTGAGACTTCCTGCGATAAAGGTTATTGGTGTTGGTGGTGC
TGGCGGTAATGCAGTAAATAGAATGATCTCTGAAGGAATACATGGGGTCACTTTTATCGCAGCAAATACCGATGTTCAGG
TACTCGAAGGCAATAAAGCAGAAATTAAAATTCAGCTTGGTAACCATCTCACACGCGGTTTGGGAGCCGGTGGAAATCCG
GAAATCGGTGAAAGGGCTGCAGAAGAAAGTATAGAAGAGGTAAGAAAAGTTCTTGAAGATACAGATCTTCTTTTCATAAC
GGCAGGAATGGGTGGTGGAACAGGAACTGGAGCCGCTCCAATCGTTGCATCCGTCGCCAAAGAGATGGGAATTTTAACGG
TAGCTGTTGTAACCACTCCGTTCTTCTTTGAGGGAAACACCAGATTGAGAGTAGCCAGCGAAGGCTTAAGAAAGCTCAGT
AAATCTGTTGACACTTTAATCAGAATTTCAAATAACAAACTGTTGCAAGAACTTCCACCTGACACCTCCATTGTTGAAGC
TTTCGCCAAAGCCGATGAAACCCTGCATCATGGAATTAAAGGTATATCGGAATTGATCACGAAACGTGGTTATATAAACC
TTGATTTCGCAGACGTTGAATCCGTGCTGCGCGACGCCGGAACGGCGATGCTTGGAATAGGTATAGGTAGAGGTGAAAAG
CGCGCCGAGGAGGCTGCAAAGGCCGCACTCGAAAGCAGGCTCCTTGAAAGACCAATTGACAATGCTATGGGAATCATTCT
CAATGTCTCTGCCAAGAATATTACCCTGAGAGAAATGAACATCGCCGCTGCAATCGTCAGACAGAACTGCAGTGAAGATG
CCGATGTTAAACTGGGTTTAATTGTCGATCAGGAAATGCCAGACGATGAACTGCACGTAACCCTCATAGCAGCCGGTCTT
GAAATGGAAGAAAGCGAACTGTTTGGTGAAGCTTCCGATATACCTGCTATTTATAGATTCGGTCTGGATACCCATGAAGA
AGAGGAAGGTACATGA

Upstream 100 bases:

>100_bases
CAGGACGCTGTGGAAACCGGAATAGAAGAAGCTATCGGAAAGCAAAAAAGAAGAGGCTTCGCTGATTTCATAAGGTCTTT
GTTCTTTGGAGGTGTTGAGG

Downstream 100 bases:

>100_bases
GGGTTTACAAACGCCTGGGTGAGCTTTTAACAGAGCGGGGCTTGATTACTCCTGAGGTTCTTCAGCAGGCCGTAACAATA
CAAAAAAAGGTTGGCAAACC

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSFEMSYEGKETDVRLPAIKVIGVGGAGGNAVNRMISEGIHGVTFIAANTDVQVLEGNKAEIKIQLGNHLTRGLGAGGNP
EIGERAAEESIEEVRKVLEDTDLLFITAGMGGGTGTGAAPIVASVAKEMGILTVAVVTTPFFFEGNTRLRVASEGLRKLS
KSVDTLIRISNNKLLQELPPDTSIVEAFAKADETLHHGIKGISELITKRGYINLDFADVESVLRDAGTAMLGIGIGRGEK
RAEEAAKAALESRLLERPIDNAMGIILNVSAKNITLREMNIAAAIVRQNCSEDADVKLGLIVDQEMPDDELHVTLIAAGL
EMEESELFGEASDIPAIYRFGLDTHEEEEGT

Sequences:

>Translated_351_residues
MSFEMSYEGKETDVRLPAIKVIGVGGAGGNAVNRMISEGIHGVTFIAANTDVQVLEGNKAEIKIQLGNHLTRGLGAGGNP
EIGERAAEESIEEVRKVLEDTDLLFITAGMGGGTGTGAAPIVASVAKEMGILTVAVVTTPFFFEGNTRLRVASEGLRKLS
KSVDTLIRISNNKLLQELPPDTSIVEAFAKADETLHHGIKGISELITKRGYINLDFADVESVLRDAGTAMLGIGIGRGEK
RAEEAAKAALESRLLERPIDNAMGIILNVSAKNITLREMNIAAAIVRQNCSEDADVKLGLIVDQEMPDDELHVTLIAAGL
EMEESELFGEASDIPAIYRFGLDTHEEEEGT
>Mature_350_residues
SFEMSYEGKETDVRLPAIKVIGVGGAGGNAVNRMISEGIHGVTFIAANTDVQVLEGNKAEIKIQLGNHLTRGLGAGGNPE
IGERAAEESIEEVRKVLEDTDLLFITAGMGGGTGTGAAPIVASVAKEMGILTVAVVTTPFFFEGNTRLRVASEGLRKLSK
SVDTLIRISNNKLLQELPPDTSIVEAFAKADETLHHGIKGISELITKRGYINLDFADVESVLRDAGTAMLGIGIGRGEKR
AEEAAKAALESRLLERPIDNAMGIILNVSAKNITLREMNIAAAIVRQNCSEDADVKLGLIVDQEMPDDELHVTLIAAGLE
MEESELFGEASDIPAIYRFGLDTHEEEEGT

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=297, Percent_Identity=48.1481481481481, Blast_Score=234, Evalue=7e-63,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: 3.4.24.-

Molecular weight: Translated: 37436; Mature: 37305

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEMSYEGKETDVRLPAIKVIGVGGAGGNAVNRMISEGIHGVTFIAANTDVQVLEGNKA
CCCCCCCCCCCCCEECCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCEEEEECCCE
EIKIQLGNHLTRGLGAGGNPEIGERAAEESIEEVRKVLEDTDLLFITAGMGGGTGTGAAP
EEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHH
IVASVAKEMGILTVAVVTTPFFFEGNTRLRVASEGLRKLSKSVDTLIRISNNKLLQELPP
HHHHHHHHHCCEEEEEECCCEEECCCCEEEEHHHHHHHHHHHHHHHEEECCCHHHHHCCC
DTSIVEAFAKADETLHHGIKGISELITKRGYINLDFADVESVLRDAGTAMLGIGIGRGEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCEEEEEECCCCHH
RAEEAAKAALESRLLERPIDNAMGIILNVSAKNITLREMNIAAAIVRQNCSEDADVKLGL
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCCCCEEEEE
IVDQEMPDDELHVTLIAAGLEMEESELFGEASDIPAIYRFGLDTHEEEEGT
EECCCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCHHEECCCCCCCCCCCC
>Mature Secondary Structure 
SFEMSYEGKETDVRLPAIKVIGVGGAGGNAVNRMISEGIHGVTFIAANTDVQVLEGNKA
CCCCCCCCCCCCEECCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCEEEEECCCE
EIKIQLGNHLTRGLGAGGNPEIGERAAEESIEEVRKVLEDTDLLFITAGMGGGTGTGAAP
EEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHH
IVASVAKEMGILTVAVVTTPFFFEGNTRLRVASEGLRKLSKSVDTLIRISNNKLLQELPP
HHHHHHHHHCCEEEEEECCCEEECCCCEEEEHHHHHHHHHHHHHHHEEECCCHHHHHCCC
DTSIVEAFAKADETLHHGIKGISELITKRGYINLDFADVESVLRDAGTAMLGIGIGRGEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCEEEEEECCCCHH
RAEEAAKAALESRLLERPIDNAMGIILNVSAKNITLREMNIAAAIVRQNCSEDADVKLGL
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCCCCEEEEE
IVDQEMPDDELHVTLIAAGLEMEESELFGEASDIPAIYRFGLDTHEEEEGT
EECCCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9605973; 10360571 [H]