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The map label for this gene is ilvE [H]

Identifier: 239616756

GI number: 239616756

Start: 367287

End: 368144

Strand: Direct

Name: ilvE [H]

Synonym: Kole_0349

Alternate gene names: 239616756

Gene position: 367287-368144 (Clockwise)

Preceding gene: 239616755

Following gene: 239616757

Centisome position: 15.95

GC content: 39.28

Gene sequence:

>858_bases
ATGTTGAATTATCTTGCAGGTCAGTGGCTGTCCGATGAGGAAGCCACCATAAATGTCAAAAATACTGGTATTTTAACAGG
AATCTCCGTATACGAGGTTCTAAGAACCTACAACGGTCTTCCTTTTGCTGCAAAAAAACATTTTGAAAGGTTGAAAAAAT
CTGCCGATTATATGGGGATACCCCTTCCGATAAATTTCGATGAATTTCTTGAGTTGCTCTTAGAAGGTGTGAAGAAAAAC
CACAATAGCAGCGGTGAAGAACTTAGAATTAAGGTAATTCTTGTACAGAGCACAAATAATTTCTCCGAGATAATAGTCCT
TTATGAAGAATTACCAAAGGTTTCTTCTGATGTTTATGAACTAGGAGTAAAAGTCGGGATATCGAAATTCATCCGTCCAT
CGGCAGCACTGGTTCCTTCAATAATCAAAATCCCGGGAGCACCATGGAAGGTTTTAACCCGCAAAGCCATGGGCGTCTAT
TACGATATGCTTCTTTTAAACGAAAAAGGAGACCTTTGTGAGGGAACTATATCCAACGTTTTCCTTATAAAAGATGAAAA
ACTCATCACTCCAAACATCGAATCAGGCATTCTACCTGGCATTACAAGAGAAAACGTGATAGGTCTTGCTAAGGCAATGG
AAATTCCGGTTGAGGAAAGAACAGTTAAAGGCTGGGAATTATTCACCGCTCAGGAAGTTTTTTTGACTCATACCAGTGCT
GGCATTGTCCCTATCAGAAAGATTGAGGACAGGGTTTATATAGAAGATTTCGCTGATGGAATAACGCGAATTCTACTTGA
CAACTTTGAGGGATTTATAATGACGAATGAATCCAACTGGGAAGGTCTATCAAAATGA

Upstream 100 bases:

>100_bases
TACGACGAATTCTATATCCCTCACAGGGTTACCGGAAGCATAGAAAATGGTTTTGTCAAGGTACAAATTGGTGGCATAGA
AGAACTGGAGGCTTTTTCGG

Downstream 100 bases:

>100_bases
AATGGAATCACCAATCACTTGACAAAATTTTTGAATCACTTTCCGGGAGTAATCCCTTTTTTAAAAAGTTGAAAGTACTT
TTACTGCAAAATAACTGGGA

Product: aminotransferase class IV

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLNYLAGQWLSDEEATINVKNTGILTGISVYEVLRTYNGLPFAAKKHFERLKKSADYMGIPLPINFDEFLELLLEGVKKN
HNSSGEELRIKVILVQSTNNFSEIIVLYEELPKVSSDVYELGVKVGISKFIRPSAALVPSIIKIPGAPWKVLTRKAMGVY
YDMLLLNEKGDLCEGTISNVFLIKDEKLITPNIESGILPGITRENVIGLAKAMEIPVEERTVKGWELFTAQEVFLTHTSA
GIVPIRKIEDRVYIEDFADGITRILLDNFEGFIMTNESNWEGLSK

Sequences:

>Translated_285_residues
MLNYLAGQWLSDEEATINVKNTGILTGISVYEVLRTYNGLPFAAKKHFERLKKSADYMGIPLPINFDEFLELLLEGVKKN
HNSSGEELRIKVILVQSTNNFSEIIVLYEELPKVSSDVYELGVKVGISKFIRPSAALVPSIIKIPGAPWKVLTRKAMGVY
YDMLLLNEKGDLCEGTISNVFLIKDEKLITPNIESGILPGITRENVIGLAKAMEIPVEERTVKGWELFTAQEVFLTHTSA
GIVPIRKIEDRVYIEDFADGITRILLDNFEGFIMTNESNWEGLSK
>Mature_285_residues
MLNYLAGQWLSDEEATINVKNTGILTGISVYEVLRTYNGLPFAAKKHFERLKKSADYMGIPLPINFDEFLELLLEGVKKN
HNSSGEELRIKVILVQSTNNFSEIIVLYEELPKVSSDVYELGVKVGISKFIRPSAALVPSIIKIPGAPWKVLTRKAMGVY
YDMLLLNEKGDLCEGTISNVFLIKDEKLITPNIESGILPGITRENVIGLAKAMEIPVEERTVKGWELFTAQEVFLTHTSA
GIVPIRKIEDRVYIEDFADGITRILLDNFEGFIMTNESNWEGLSK

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=298, Percent_Identity=26.8456375838926, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 31985; Mature: 31985

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYLAGQWLSDEEATINVKNTGILTGISVYEVLRTYNGLPFAAKKHFERLKKSADYMGI
CCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
PLPINFDEFLELLLEGVKKNHNSSGEELRIKVILVQSTNNFSEIIVLYEELPKVSSDVYE
CCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHH
LGVKVGISKFIRPSAALVPSIIKIPGAPWKVLTRKAMGVYYDMLLLNEKGDLCEGTISNV
HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEE
FLIKDEKLITPNIESGILPGITRENVIGLAKAMEIPVEERTVKGWELFTAQEVFLTHTSA
EEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCEEEEEHHEEEEEECCC
GIVPIRKIEDRVYIEDFADGITRILLDNFEGFIMTNESNWEGLSK
CCEEHHHHCCEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MLNYLAGQWLSDEEATINVKNTGILTGISVYEVLRTYNGLPFAAKKHFERLKKSADYMGI
CCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
PLPINFDEFLELLLEGVKKNHNSSGEELRIKVILVQSTNNFSEIIVLYEELPKVSSDVYE
CCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHH
LGVKVGISKFIRPSAALVPSIIKIPGAPWKVLTRKAMGVYYDMLLLNEKGDLCEGTISNV
HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEE
FLIKDEKLITPNIESGILPGITRENVIGLAKAMEIPVEERTVKGWELFTAQEVFLTHTSA
EEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCEEEEEHHEEEEEECCC
GIVPIRKIEDRVYIEDFADGITRILLDNFEGFIMTNESNWEGLSK
CCEEHHHHCCEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 8863738 [H]