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The map label for this gene is prmA [H]

Identifier: 239616734

GI number: 239616734

Start: 347887

End: 348708

Strand: Direct

Name: prmA [H]

Synonym: Kole_0327

Alternate gene names: 239616734

Gene position: 347887-348708 (Clockwise)

Preceding gene: 239616712

Following gene: 239616735

Centisome position: 15.11

GC content: 40.63

Gene sequence:

>822_bases
ATGTTTGAAAGATACAAACACTTTGTGGCGATTGTAAACAATGAAACGCGTGAAGAACTCGAAGACTTATCCGTTAAAAA
CGGTTTCTTTAACATCTATTTCGAAAACGTGTCTGATGGAGAATGGATTGCCCATCTTTATCTGGTGGCAGATGAAGAAG
TTCCCGATTTTTTGAAGGATTTCCCATTCAAATATCTGGAAGATGAAAGCAGCGATAATTGGCATAAAAAATTTAGAGAG
AGCTTAAAACCTTTCGAACTCTGTGACGGTATAACTGTTGTCCCGCTTGAAAAACCAGCACCGATTTATCAAAATGATCA
GATTGGTATAATTCCTGGATTAGCATTTGGAACTGGGCTGCATGAGAGCACCAGATTAGCAGCCGAATTATTGAAAAAGT
TCCTTAAGCCCGGAGACAGTCTGCTGGATGTGGGGTGCGGCACCGGAATCCTTTCGGTGCTAGCGGCAAAGCTCAGGGCA
GGGCACGTTGTTGGAATCGATAACGATCCAAATGCCATAGAAAAGACACGTGAGACGTCTAAAATCAACGGGGTATCGTT
GAACATACTAGAATCTAATTTCCTTCAGGCTCTGGCTTCAGATGAAAAATTTCATATCATAGTATCTAATATGATCGTCG
AGCTTCTCAGCAAGTTCTACGAAGACGCAAAAAACTTCCTTTATGACGATGGAATACTGATACTTTCAGGAATCATCAGT
AACAAAGAAGAAAAGTTCACAGAAGAACTAAAGCGTCATTATTTGCTTCTGGAACGAAAGGCGGAAGGAGAATGGGTGGC
TTTAGCAATGAAAAAGAAATAA

Upstream 100 bases:

>100_bases
CTCCCATTTTTACAAAAGTATTGTAGCATCATATATTGAAAAGCTTGTAAAAGCTATCGGGTAATTTTACTCTGAATCAT
AACCTAACAGGAGTGATGGA

Downstream 100 bases:

>100_bases
TAAAGCTTCAGCTTGGTAGAGATATAGAAAATGATTTTACCGTTGTTAGAAGGTGTAGCTGGGGATATCCGCAGTGTATA
AAATCTTCATTGATTACAAA

Product: ribosomal L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MFERYKHFVAIVNNETREELEDLSVKNGFFNIYFENVSDGEWIAHLYLVADEEVPDFLKDFPFKYLEDESSDNWHKKFRE
SLKPFELCDGITVVPLEKPAPIYQNDQIGIIPGLAFGTGLHESTRLAAELLKKFLKPGDSLLDVGCGTGILSVLAAKLRA
GHVVGIDNDPNAIEKTRETSKINGVSLNILESNFLQALASDEKFHIIVSNMIVELLSKFYEDAKNFLYDDGILILSGIIS
NKEEKFTEELKRHYLLLERKAEGEWVALAMKKK

Sequences:

>Translated_273_residues
MFERYKHFVAIVNNETREELEDLSVKNGFFNIYFENVSDGEWIAHLYLVADEEVPDFLKDFPFKYLEDESSDNWHKKFRE
SLKPFELCDGITVVPLEKPAPIYQNDQIGIIPGLAFGTGLHESTRLAAELLKKFLKPGDSLLDVGCGTGILSVLAAKLRA
GHVVGIDNDPNAIEKTRETSKINGVSLNILESNFLQALASDEKFHIIVSNMIVELLSKFYEDAKNFLYDDGILILSGIIS
NKEEKFTEELKRHYLLLERKAEGEWVALAMKKK
>Mature_273_residues
MFERYKHFVAIVNNETREELEDLSVKNGFFNIYFENVSDGEWIAHLYLVADEEVPDFLKDFPFKYLEDESSDNWHKKFRE
SLKPFELCDGITVVPLEKPAPIYQNDQIGIIPGLAFGTGLHESTRLAAELLKKFLKPGDSLLDVGCGTGILSVLAAKLRA
GHVVGIDNDPNAIEKTRETSKINGVSLNILESNFLQALASDEKFHIIVSNMIVELLSKFYEDAKNFLYDDGILILSGIIS
NKEEKFTEELKRHYLLLERKAEGEWVALAMKKK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=157, Percent_Identity=31.2101910828025, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31018; Mature: 31018

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERYKHFVAIVNNETREELEDLSVKNGFFNIYFENVSDGEWIAHLYLVADEEVPDFLKD
CCCHHEEHEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEEECCCHHHHHHH
FPFKYLEDESSDNWHKKFRESLKPFELCDGITVVPLEKPAPIYQNDQIGIIPGLAFGTGL
CCHHHHCCCCCCHHHHHHHHCCCCHHHHCCCEEEECCCCCCCCCCCCEEEECCHHHCCCC
HESTRLAAELLKKFLKPGDSLLDVGCGTGILSVLAAKLRAGHVVGIDNDPNAIEKTRETS
CHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHH
KINGVSLNILESNFLQALASDEKFHIIVSNMIVELLSKFYEDAKNFLYDDGILILSGIIS
HCCCEEEEHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
NKEEKFTEELKRHYLLLERKAEGEWVALAMKKK
CHHHHHHHHHHHHHHHHEECCCCCEEEEEEECC
>Mature Secondary Structure
MFERYKHFVAIVNNETREELEDLSVKNGFFNIYFENVSDGEWIAHLYLVADEEVPDFLKD
CCCHHEEHEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEEECCCHHHHHHH
FPFKYLEDESSDNWHKKFRESLKPFELCDGITVVPLEKPAPIYQNDQIGIIPGLAFGTGL
CCHHHHCCCCCCHHHHHHHHCCCCHHHHCCCEEEECCCCCCCCCCCCEEEECCHHHCCCC
HESTRLAAELLKKFLKPGDSLLDVGCGTGILSVLAAKLRAGHVVGIDNDPNAIEKTRETS
CHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHH
KINGVSLNILESNFLQALASDEKFHIIVSNMIVELLSKFYEDAKNFLYDDGILILSGIIS
HCCCEEEEHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
NKEEKFTEELKRHYLLLERKAEGEWVALAMKKK
CHHHHHHHHHHHHHHHHEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]