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The map label for this gene is murB [H]

Identifier: 239616668

GI number: 239616668

Start: 287413

End: 288312

Strand: Direct

Name: murB [H]

Synonym: Kole_0261

Alternate gene names: 239616668

Gene position: 287413-288312 (Clockwise)

Preceding gene: 239616667

Following gene: 239616669

Centisome position: 12.48

GC content: 44.11

Gene sequence:

>900_bases
GTGAGTCTAAATAATAAGCTTTTCCGGAAATTGTACCTTTCAGGTTGCGAAATAAAGCTCGACGAATCTCTCGCAAACTA
TACCACAATAAGAATTGGTGGAAGAGTCGATGCGGTCGTTTTTCCGATGACCATTCAGGCTTTCTCGAAATGCCTGGAGG
TTTTAAAAGCTCATTCGGTCCCTTTCAAAATCCTCGGCGGAGGGTCTAACGTTGTTCCTCCAAAAAGCTTCAATGGCATT
GCCGTCCATACTCGATATTTAGCGAACGTTAGAATCTCTGGAAACAAGATAACAGCTGAATGTGGTGTGCCTCTTAGAAG
GGTTCTGGATATAGCCGCTGAGGGGGGGCTCTCCGGCCTGGAGTTCGCTTCCGGAATACCAGGAACTCTTGGTGGTGCTC
TTTACATGAACGCAGGCGCTTTCGGCGGAGAGATGTCTCAGGTCGTTGAGTCAGTGAGCGTTTTAGACGATAATTTGAAG
CCAAAAAAACTATCCGTAGAGGAAATAGGTTATGGTTACAGACAGAGTTTGTTTAAAAAGAACGGTCTAACTATTCTCAG
CGCGACTCTTTCATTACACGAAGGTAAGCCAGAAAAGATTCGTGAGAAGATGCAAGAGATATTATCGAAGAGACTGGAAA
AACAACCGATACACCTTCCAAGTGCTGGTAGTGTGTTCTTGCGTCCCAAACCGGATTTTTATGTTGGCTCTACCATTGAC
AAACTCGGATTAAAAGGACTAAGAGTTGGTGGCGTTGAAGTGTCCAGGAAACATGCGGGATTTATTGTAAACGTAGGAGG
AGGTACACAGAGAGATTTGGTAGAACTAATTGAAAAAATAAAAGCGCGGGTTTATGAAAAAACGGGAGTTATCCTACAAA
CCGAGATCGACATCTGGTAA

Upstream 100 bases:

>100_bases
CAGATGTTGCTTGTGAATCGGCCGGAATTCATAGAAGTAGTTAAGAATTTGAAGAGTGGGAAAGAAATCATCGACAAAAT
CTACTTCTGGGGCGAAAATT

Downstream 100 bases:

>100_bases
AGGAAAGGAGTGATCCTATGACAGAAATAGGTGAATTACCTGAAAGAAGACCCTCTTTTAAGTTCATGAGTGGTTTTGTT
ATTGTGTTTGTAATAATCGC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSLNNKLFRKLYLSGCEIKLDESLANYTTIRIGGRVDAVVFPMTIQAFSKCLEVLKAHSVPFKILGGGSNVVPPKSFNGI
AVHTRYLANVRISGNKITAECGVPLRRVLDIAAEGGLSGLEFASGIPGTLGGALYMNAGAFGGEMSQVVESVSVLDDNLK
PKKLSVEEIGYGYRQSLFKKNGLTILSATLSLHEGKPEKIREKMQEILSKRLEKQPIHLPSAGSVFLRPKPDFYVGSTID
KLGLKGLRVGGVEVSRKHAGFIVNVGGGTQRDLVELIEKIKARVYEKTGVILQTEIDIW

Sequences:

>Translated_299_residues
MSLNNKLFRKLYLSGCEIKLDESLANYTTIRIGGRVDAVVFPMTIQAFSKCLEVLKAHSVPFKILGGGSNVVPPKSFNGI
AVHTRYLANVRISGNKITAECGVPLRRVLDIAAEGGLSGLEFASGIPGTLGGALYMNAGAFGGEMSQVVESVSVLDDNLK
PKKLSVEEIGYGYRQSLFKKNGLTILSATLSLHEGKPEKIREKMQEILSKRLEKQPIHLPSAGSVFLRPKPDFYVGSTID
KLGLKGLRVGGVEVSRKHAGFIVNVGGGTQRDLVELIEKIKARVYEKTGVILQTEIDIW
>Mature_298_residues
SLNNKLFRKLYLSGCEIKLDESLANYTTIRIGGRVDAVVFPMTIQAFSKCLEVLKAHSVPFKILGGGSNVVPPKSFNGIA
VHTRYLANVRISGNKITAECGVPLRRVLDIAAEGGLSGLEFASGIPGTLGGALYMNAGAFGGEMSQVVESVSVLDDNLKP
KKLSVEEIGYGYRQSLFKKNGLTILSATLSLHEGKPEKIREKMQEILSKRLEKQPIHLPSAGSVFLRPKPDFYVGSTIDK
LGLKGLRVGGVEVSRKHAGFIVNVGGGTQRDLVELIEKIKARVYEKTGVILQTEIDIW

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32454; Mature: 32323

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNNKLFRKLYLSGCEIKLDESLANYTTIRIGGRVDAVVFPMTIQAFSKCLEVLKAHSV
CCCCHHHHHHHHHCCCCEEECCCCCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCC
PFKILGGGSNVVPPKSFNGIAVHTRYLANVRISGNKITAECGVPLRRVLDIAAEGGLSGL
CEEEECCCCCCCCCCCCCCEEEEEEEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCH
EFASGIPGTLGGALYMNAGAFGGEMSQVVESVSVLDDNLKPKKLSVEEIGYGYRQSLFKK
HHHCCCCCHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCEECHHHHCCHHHHHHHHC
NGLTILSATLSLHEGKPEKIREKMQEILSKRLEKQPIHLPSAGSVFLRPKPDFYVGSTID
CCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEECCCHH
KLGLKGLRVGGVEVSRKHAGFIVNVGGGTQRDLVELIEKIKARVYEKTGVILQTEIDIW
HHCCCCEEECCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
>Mature Secondary Structure 
SLNNKLFRKLYLSGCEIKLDESLANYTTIRIGGRVDAVVFPMTIQAFSKCLEVLKAHSV
CCCHHHHHHHHHCCCCEEECCCCCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCC
PFKILGGGSNVVPPKSFNGIAVHTRYLANVRISGNKITAECGVPLRRVLDIAAEGGLSGL
CEEEECCCCCCCCCCCCCCEEEEEEEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCH
EFASGIPGTLGGALYMNAGAFGGEMSQVVESVSVLDDNLKPKKLSVEEIGYGYRQSLFKK
HHHCCCCCHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCEECHHHHCCHHHHHHHHC
NGLTILSATLSLHEGKPEKIREKMQEILSKRLEKQPIHLPSAGSVFLRPKPDFYVGSTID
CCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEECCCHH
KLGLKGLRVGGVEVSRKHAGFIVNVGGGTQRDLVELIEKIKARVYEKTGVILQTEIDIW
HHCCCCEEECCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA