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The map label for this gene is hflK [H]

Identifier: 239616669

GI number: 239616669

Start: 288330

End: 289295

Strand: Direct

Name: hflK [H]

Synonym: Kole_0262

Alternate gene names: 239616669

Gene position: 288330-289295 (Clockwise)

Preceding gene: 239616668

Following gene: 239616670

Centisome position: 12.52

GC content: 43.89

Gene sequence:

>966_bases
ATGACAGAAATAGGTGAATTACCTGAAAGAAGACCCTCTTTTAAGTTCATGAGTGGTTTTGTTATTGTGTTTGTAATAAT
CGCAATTGTCGTTGTTTATTTCCTGTCAGGTTTTTTCTTCGTTGGACCGGCAGAGGTTGGGTTAGTCAAACGATTCGGTG
CCCACATAAAAACCGTTGGTCCTGGCTTACACTATCATCTCCCATACCCTATCGAAAGCGTTGTTAAGGTCAATGTTTCC
GCACTCAGAAAACAGGAGATAGGATTCAGAACAGTTTCGCCAGGAAGATACACCTCAGTAAAGAATGAATCGTTGATGTT
GACAGGCGATGGAAATATCGTCTCTGTGGAAGCAGTTGTTCAGTACTATGTGAAAGATCCTGAGCAGTTTGCTTTTAACC
TGATTAATGACGAGCAGGTGGTCCGTTTCGTCTCTGAAGCCATCCTCAGGGAAGAGGTTGCCGCCGCGAGTATAGATGAA
GTCCTCACATTCGAGAGGGATGTAATCGCAGCAAAAACGGCTGAGCGAGTCCAGGATGTTTTAGACCAGCTCAATGTTGG
CATCGAGGTAAAGAACGTTTATCTCCAGGAGGTCAGTCCACCTGAACAGGTTGTTGCCGCATTCGACGACGTCAACAACG
CGAAGCAAGATAAAGAAAAGCTGAGAAATGAAGCAGAAAGATACAAGAACGATTTAATTCCACGTGCTGAAGGTGAAGCC
GTCCAGATAGTAAGAGAGGCGGAAGCCTATGCTGAAGAATTGATCCTCAAAGCAAAGGGTGAAGCAGAGAGATTCACAAA
GGTTTTTGGAGAATACAAAAAGGCGCCGAAAATAACCCGTACAAGGCTTTATCTCGAAATGCTGAACAGAATCCTTAAAG
ATTCTGAAAAATTCGTTCTCCTTAGTAAAGATGGAGTATTGAAGTTCCTGGACCTCTCCAAAATGGAAGAAGGTGGTAGC
CGATGA

Upstream 100 bases:

>100_bases
TGGTAGAACTAATTGAAAAAATAAAAGCGCGGGTTTATGAAAAAACGGGAGTTATCCTACAAACCGAGATCGACATCTGG
TAAAGGAAAGGAGTGATCCT

Downstream 100 bases:

>100_bases
AAGCCATAATAACAATTGTGATTCTGGCGATTATTGCTCTGATACTTGTACCTGAATTCTTCTACATTGTAGATCAAACC
AAACAGGCGGTCGTTCTCCG

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTEIGELPERRPSFKFMSGFVIVFVIIAIVVVYFLSGFFFVGPAEVGLVKRFGAHIKTVGPGLHYHLPYPIESVVKVNVS
ALRKQEIGFRTVSPGRYTSVKNESLMLTGDGNIVSVEAVVQYYVKDPEQFAFNLINDEQVVRFVSEAILREEVAAASIDE
VLTFERDVIAAKTAERVQDVLDQLNVGIEVKNVYLQEVSPPEQVVAAFDDVNNAKQDKEKLRNEAERYKNDLIPRAEGEA
VQIVREAEAYAEELILKAKGEAERFTKVFGEYKKAPKITRTRLYLEMLNRILKDSEKFVLLSKDGVLKFLDLSKMEEGGS
R

Sequences:

>Translated_321_residues
MTEIGELPERRPSFKFMSGFVIVFVIIAIVVVYFLSGFFFVGPAEVGLVKRFGAHIKTVGPGLHYHLPYPIESVVKVNVS
ALRKQEIGFRTVSPGRYTSVKNESLMLTGDGNIVSVEAVVQYYVKDPEQFAFNLINDEQVVRFVSEAILREEVAAASIDE
VLTFERDVIAAKTAERVQDVLDQLNVGIEVKNVYLQEVSPPEQVVAAFDDVNNAKQDKEKLRNEAERYKNDLIPRAEGEA
VQIVREAEAYAEELILKAKGEAERFTKVFGEYKKAPKITRTRLYLEMLNRILKDSEKFVLLSKDGVLKFLDLSKMEEGGS
R
>Mature_320_residues
TEIGELPERRPSFKFMSGFVIVFVIIAIVVVYFLSGFFFVGPAEVGLVKRFGAHIKTVGPGLHYHLPYPIESVVKVNVSA
LRKQEIGFRTVSPGRYTSVKNESLMLTGDGNIVSVEAVVQYYVKDPEQFAFNLINDEQVVRFVSEAILREEVAAASIDEV
LTFERDVIAAKTAERVQDVLDQLNVGIEVKNVYLQEVSPPEQVVAAFDDVNNAKQDKEKLRNEAERYKNDLIPRAEGEAV
QIVREAEAYAEELILKAKGEAERFTKVFGEYKKAPKITRTRLYLEMLNRILKDSEKFVLLSKDGVLKFLDLSKMEEGGSR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=285, Percent_Identity=36.8421052631579, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 36202; Mature: 36071

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIGELPERRPSFKFMSGFVIVFVIIAIVVVYFLSGFFFVGPAEVGLVKRFGAHIKTVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCHHEECC
PGLHYHLPYPIESVVKVNVSALRKQEIGFRTVSPGRYTSVKNESLMLTGDGNIVSVEAVV
CCCEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEEECCCCEEEHHHHH
QYYVKDPEQFAFNLINDEQVVRFVSEAILREEVAAASIDEVLTFERDVIAAKTAERVQDV
HHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDQLNVGIEVKNVYLQEVSPPEQVVAAFDDVNNAKQDKEKLRNEAERYKNDLIPRAEGEA
HHHHCCCEEEEEEHEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
VQIVREAEAYAEELILKAKGEAERFTKVFGEYKKAPKITRTRLYLEMLNRILKDSEKFVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEE
LSKDGVLKFLDLSKMEEGGSR
EECCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEIGELPERRPSFKFMSGFVIVFVIIAIVVVYFLSGFFFVGPAEVGLVKRFGAHIKTVG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCHHEECC
PGLHYHLPYPIESVVKVNVSALRKQEIGFRTVSPGRYTSVKNESLMLTGDGNIVSVEAVV
CCCEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEEECCCCEEEHHHHH
QYYVKDPEQFAFNLINDEQVVRFVSEAILREEVAAASIDEVLTFERDVIAAKTAERVQDV
HHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDQLNVGIEVKNVYLQEVSPPEQVVAAFDDVNNAKQDKEKLRNEAERYKNDLIPRAEGEA
HHHHCCCEEEEEEHEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
VQIVREAEAYAEELILKAKGEAERFTKVFGEYKKAPKITRTRLYLEMLNRILKDSEKFVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEE
LSKDGVLKFLDLSKMEEGGSR
EECCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]