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The map label for this gene is gcp

Identifier: 239616658

GI number: 239616658

Start: 280657

End: 281649

Strand: Direct

Name: gcp

Synonym: Kole_0251

Alternate gene names: 239616658

Gene position: 280657-281649 (Clockwise)

Preceding gene: 239616657

Following gene: 239616666

Centisome position: 12.19

GC content: 43.91

Gene sequence:

>993_bases
ATGAGAGTACTGGCAATAGAAAGTTCCTGCGATGAAACAGCCGTTGCTATAGTTGAAGACGGCAAGCTCCTATCCAGTGT
TCTTTCTTCACAGGTAAATATTCACCGCAAATATGGCGGTGTAGTTCCCGAAATAGCAGCAAGAAAACACCTTGAAAATA
TTCTGTTCCTTCTGGATGAAGCCCTGGATAGAGCAAGCTTAAAGATCGACGATATCGATGTATTCGCGGCTACTCAGGGA
CCGGGATTGGTGGGTTCACTTCTTGTAGGTTTATCGCTGGCTAAGGGGCTTTCCATCTCGCTCAACAAACCATTCGTTGC
AGTCAACCATCTCATCGGGCATATTTATGCCAATTTTTTGAGTTTTCCAGATCTAGAATATCCTTTTCTGGTTTTGCTCG
TTTCCGGCGGACACACAGAAATTCTACTTGCCGAGGATTGGAATAATTTTAAGCGTATAGGAAAAACACGTGATGATGCG
GCCGGTGAGGCTTTTGACAAGGTTGCCCGACTCCTTGGATTGGGTTATCCAGGAGGGCCAGAGGTCGAACTAGCTGCCAG
AAACGGAAATCCAATTTATCGTTTTCCCCGTGCTCTCAACGAGAAGGGAAATTTTGATTTTAGCTTCAGCGGGTTGAAAA
CTTCTGTCCTTTACTTTCTAAAGAACAATCCTGAGGCTCGAATCGAGGATGTAGCTGCCGCTTTTCAGGAAGCGGTGATT
GATTCTTTGCTTACCAAAACCTTTGCTGCGGCTAAAACATATGGCATTAACAAAATTGTTTTTGCCGGTGGCGTAGCTGC
TAACACCAGATTAAGAGAGCGTGCGAATGAGATTGCAAAAGAGAAAGATATAAATATTTACTTTCCACCAATAGAATTTT
GCACCGACAACGCCGCGATGATAGCTATGGTAGCTTACGAAAAAGCAAAAAGGGGGATTTTCTCCCCCATAGATACCAAT
GCTATACCTTATCTCTCAATCGTTAGTCTTTGA

Upstream 100 bases:

>100_bases
TTGAAGCTCCAAGTATGGAGAATGTTGAAAAGATCATCATGACCAAAGATGTTATAGAGGGACGCGCAAAACCTGAAATA
ATAACGAGGGAATCAGCCTG

Downstream 100 bases:

>100_bases
AGTGTTGTTAGTGGTTTCTTTGGAACTGCTGGAATCATTCGATGTTTTTTTTGAGTCTGTGGAGTAGAAGCCGCTTCCTT
TGAATACAACACCAATGTTG

Product: metalloendopeptidase, glycoprotease family

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MRVLAIESSCDETAVAIVEDGKLLSSVLSSQVNIHRKYGGVVPEIAARKHLENILFLLDEALDRASLKIDDIDVFAATQG
PGLVGSLLVGLSLAKGLSISLNKPFVAVNHLIGHIYANFLSFPDLEYPFLVLLVSGGHTEILLAEDWNNFKRIGKTRDDA
AGEAFDKVARLLGLGYPGGPEVELAARNGNPIYRFPRALNEKGNFDFSFSGLKTSVLYFLKNNPEARIEDVAAAFQEAVI
DSLLTKTFAAAKTYGINKIVFAGGVAANTRLRERANEIAKEKDINIYFPPIEFCTDNAAMIAMVAYEKAKRGIFSPIDTN
AIPYLSIVSL

Sequences:

>Translated_330_residues
MRVLAIESSCDETAVAIVEDGKLLSSVLSSQVNIHRKYGGVVPEIAARKHLENILFLLDEALDRASLKIDDIDVFAATQG
PGLVGSLLVGLSLAKGLSISLNKPFVAVNHLIGHIYANFLSFPDLEYPFLVLLVSGGHTEILLAEDWNNFKRIGKTRDDA
AGEAFDKVARLLGLGYPGGPEVELAARNGNPIYRFPRALNEKGNFDFSFSGLKTSVLYFLKNNPEARIEDVAAAFQEAVI
DSLLTKTFAAAKTYGINKIVFAGGVAANTRLRERANEIAKEKDINIYFPPIEFCTDNAAMIAMVAYEKAKRGIFSPIDTN
AIPYLSIVSL
>Mature_330_residues
MRVLAIESSCDETAVAIVEDGKLLSSVLSSQVNIHRKYGGVVPEIAARKHLENILFLLDEALDRASLKIDDIDVFAATQG
PGLVGSLLVGLSLAKGLSISLNKPFVAVNHLIGHIYANFLSFPDLEYPFLVLLVSGGHTEILLAEDWNNFKRIGKTRDDA
AGEAFDKVARLLGLGYPGGPEVELAARNGNPIYRFPRALNEKGNFDFSFSGLKTSVLYFLKNNPEARIEDVAAAFQEAVI
DSLLTKTFAAAKTYGINKIVFAGGVAANTRLRERANEIAKEKDINIYFPPIEFCTDNAAMIAMVAYEKAKRGIFSPIDTN
AIPYLSIVSL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=349, Percent_Identity=34.3839541547278, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI8923380, Length=330, Percent_Identity=32.1212121212121, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=42.5149700598802, Blast_Score=268, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=323, Percent_Identity=33.1269349845201, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=314, Percent_Identity=31.5286624203822, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320099, Length=347, Percent_Identity=29.971181556196, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322891, Length=298, Percent_Identity=28.5234899328859, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI20129063, Length=337, Percent_Identity=33.2344213649852, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI21357207, Length=340, Percent_Identity=30.5882352941176, Blast_Score=141, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_KOSOT (C5CD32)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002939980.1
- GeneID:   7969003
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_0251
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35909; Mature: 35909

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLAIESSCDETAVAIVEDGKLLSSVLSSQVNIHRKYGGVVPEIAARKHLENILFLLDE
CEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALDRASLKIDDIDVFAATQGPGLVGSLLVGLSLAKGLSISLNKPFVAVNHLIGHIYANFL
HHHHHCCEEECEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHH
SFPDLEYPFLVLLVSGGHTEILLAEDWNNFKRIGKTRDDAAGEAFDKVARLLGLGYPGGP
CCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
EVELAARNGNPIYRFPRALNEKGNFDFSFSGLKTSVLYFLKNNPEARIEDVAAAFQEAVI
CEEEEECCCCCCEECHHHHCCCCCCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
DSLLTKTFAAAKTYGINKIVFAGGVAANTRLRERANEIAKEKDINIYFPPIEFCTDNAAM
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHCCCCCE
IAMVAYEKAKRGIFSPIDTNAIPYLSIVSL
EHHHHHHHHHCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MRVLAIESSCDETAVAIVEDGKLLSSVLSSQVNIHRKYGGVVPEIAARKHLENILFLLDE
CEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALDRASLKIDDIDVFAATQGPGLVGSLLVGLSLAKGLSISLNKPFVAVNHLIGHIYANFL
HHHHHCCEEECEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHH
SFPDLEYPFLVLLVSGGHTEILLAEDWNNFKRIGKTRDDAAGEAFDKVARLLGLGYPGGP
CCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
EVELAARNGNPIYRFPRALNEKGNFDFSFSGLKTSVLYFLKNNPEARIEDVAAAFQEAVI
CEEEEECCCCCCEECHHHHCCCCCCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
DSLLTKTFAAAKTYGINKIVFAGGVAANTRLRERANEIAKEKDINIYFPPIEFCTDNAAM
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHCCCCCE
IAMVAYEKAKRGIFSPIDTNAIPYLSIVSL
EHHHHHHHHHCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA