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The map label for this gene is clpX [H]

Identifier: 239616657

GI number: 239616657

Start: 279446

End: 280657

Strand: Direct

Name: clpX [H]

Synonym: Kole_0250

Alternate gene names: 239616657

Gene position: 279446-280657 (Clockwise)

Preceding gene: 239616653

Following gene: 239616658

Centisome position: 12.14

GC content: 44.55

Gene sequence:

>1212_bases
TTGCCATTCGAAAGAAAATGTTCATTTTGTGGAAGACCTGCTTCTCAGGTAAAAAAGTTAATATCCGGAGCAGAAGGTTA
CATCTGTGACGAGTGTGTTGAACTATTCCACGATATTCTAAAAGAAGATACAAAGGTGAGGCGGGAACCCGGGAAAAAGC
TGCCGAAACCTGCCGAAATAAAGGCAATACTGGATCAGTACGTTATCGGTCAGGAAAAGGCAAAGAAAACAATCTCTGTC
GCTGTTTATAACCATTACAAACGTGTTTTCATTGGAAGCGATGACATCGAAGTGGAAAAGTCCAACATTATGTTAATCGG
TCCCACAGGCTCCGGAAAAACGCTGATTGCCCGAACTCTGGCAAAGATTCTCGATGTCCCTTTTGCCATAGCTGACGCTA
CACCGTTGACTGAAGCCGGTTATGTTGGCGAAGATGTGGAGAATGTTATCCTGAGGCTTTTACAAGCTGCAAATTTTGAT
GTAGAACGCGCGCAATACGGAATCATATATATTGACGAGATAGATAAAATAACGCGCAAAACCTCCAATCCGTCCATAAC
CAGAGACGTTTCCGGCGAGGGCGTCCAACAGGCACTTTTGAAGATAGTGGAGGGTACAATTGCAAATGTTCCGCCTCAGG
GAGGAAGAAAACATCCCTATCAGGAGTTCATAAAGATCGACACCACCAATATCCTTTTCATCGTTGGTGGAGCCTTTGAC
GGCCTGGATGAGATTATAAAAGAGAGGATCTTGACCTCTACCATGGGGTTCGGGGCAGAGGTCAAAGGAAAAGATTCCTA
TCGCCTTGGCGAAATTCTTGCTCAGGTTGGTCCGGATGACTTGATTCACTACGGTATGATTCCAGAGTTTGTCGGCAGAT
TTCCCGTGGTCGCCACACTGGATGACTTGAGTGTAGAAGATTTGAAAAGAATAATGCTGGAACCAAAGAATGCCGTCATA
AAACAGTACCAGAAACTCCTGGAGATCGAAGGTATAACACTTCAATTTACCGAAGACGCATTGACTGCTATCGCCAAAGA
AGCCTTGAAGCGGGGTACCGGCGCGAGGGCAATAAAGAGCGTTATAGAATCTGTTATGCTCGATATTATGTTTGAAGCTC
CAAGTATGGAGAATGTTGAAAAGATCATCATGACCAAAGATGTTATAGAGGGACGCGCAAAACCTGAAATAATAACGAGG
GAATCAGCCTGA

Upstream 100 bases:

>100_bases
TTTTCATCCTCCATTCTCGGGATTTTTCATACATCCCCTCATTAAGAGTGTATAATATATTGAAGAAATTTGGACCAAAT
AGATTTGGGAGGTAATATCT

Downstream 100 bases:

>100_bases
TGAGAGTACTGGCAATAGAAAGTTCCTGCGATGAAACAGCCGTTGCTATAGTTGAAGACGGCAAGCTCCTATCCAGTGTT
CTTTCTTCACAGGTAAATAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPFERKCSFCGRPASQVKKLISGAEGYICDECVELFHDILKEDTKVRREPGKKLPKPAEIKAILDQYVIGQEKAKKTISV
AVYNHYKRVFIGSDDIEVEKSNIMLIGPTGSGKTLIARTLAKILDVPFAIADATPLTEAGYVGEDVENVILRLLQAANFD
VERAQYGIIYIDEIDKITRKTSNPSITRDVSGEGVQQALLKIVEGTIANVPPQGGRKHPYQEFIKIDTTNILFIVGGAFD
GLDEIIKERILTSTMGFGAEVKGKDSYRLGEILAQVGPDDLIHYGMIPEFVGRFPVVATLDDLSVEDLKRIMLEPKNAVI
KQYQKLLEIEGITLQFTEDALTAIAKEALKRGTGARAIKSVIESVMLDIMFEAPSMENVEKIIMTKDVIEGRAKPEIITR
ESA

Sequences:

>Translated_403_residues
MPFERKCSFCGRPASQVKKLISGAEGYICDECVELFHDILKEDTKVRREPGKKLPKPAEIKAILDQYVIGQEKAKKTISV
AVYNHYKRVFIGSDDIEVEKSNIMLIGPTGSGKTLIARTLAKILDVPFAIADATPLTEAGYVGEDVENVILRLLQAANFD
VERAQYGIIYIDEIDKITRKTSNPSITRDVSGEGVQQALLKIVEGTIANVPPQGGRKHPYQEFIKIDTTNILFIVGGAFD
GLDEIIKERILTSTMGFGAEVKGKDSYRLGEILAQVGPDDLIHYGMIPEFVGRFPVVATLDDLSVEDLKRIMLEPKNAVI
KQYQKLLEIEGITLQFTEDALTAIAKEALKRGTGARAIKSVIESVMLDIMFEAPSMENVEKIIMTKDVIEGRAKPEIITR
ESA
>Mature_402_residues
PFERKCSFCGRPASQVKKLISGAEGYICDECVELFHDILKEDTKVRREPGKKLPKPAEIKAILDQYVIGQEKAKKTISVA
VYNHYKRVFIGSDDIEVEKSNIMLIGPTGSGKTLIARTLAKILDVPFAIADATPLTEAGYVGEDVENVILRLLQAANFDV
ERAQYGIIYIDEIDKITRKTSNPSITRDVSGEGVQQALLKIVEGTIANVPPQGGRKHPYQEFIKIDTTNILFIVGGAFDG
LDEIIKERILTSTMGFGAEVKGKDSYRLGEILAQVGPDDLIHYGMIPEFVGRFPVVATLDDLSVEDLKRIMLEPKNAVIK
QYQKLLEIEGITLQFTEDALTAIAKEALKRGTGARAIKSVIESVMLDIMFEAPSMENVEKIIMTKDVIEGRAKPEIITRE
SA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=337, Percent_Identity=51.3353115727003, Blast_Score=304, Evalue=1e-82,
Organism=Escherichia coli, GI1786642, Length=398, Percent_Identity=61.3065326633166, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1790366, Length=219, Percent_Identity=31.9634703196347, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=320, Percent_Identity=43.4375, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71982908, Length=320, Percent_Identity=43.4375, Blast_Score=264, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=306, Percent_Identity=41.1764705882353, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI71988660, Length=161, Percent_Identity=48.4472049689441, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319704, Length=409, Percent_Identity=38.1418092909535, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=47.9750778816199, Blast_Score=300, Evalue=9e-82,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=47.9750778816199, Blast_Score=300, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 44572; Mature: 44441

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFERKCSFCGRPASQVKKLISGAEGYICDECVELFHDILKEDTKVRREPGKKLPKPAEI
CCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KAILDQYVIGQEKAKKTISVAVYNHYKRVFIGSDDIEVEKSNIMLIGPTGSGKTLIARTL
HHHHHHHHHCHHHHHHHEEHEEECCCEEEEECCCCCEEEECCEEEEECCCCCHHHHHHHH
AKILDVPFAIADATPLTEAGYVGEDVENVILRLLQAANFDVERAQYGIIYIDEIDKITRK
HHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEECHHHHHHC
TSNPSITRDVSGEGVQQALLKIVEGTIANVPPQGGRKHPYQEFIKIDTTNILFIVGGAFD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCEEEEEECCCCC
GLDEIIKERILTSTMGFGAEVKGKDSYRLGEILAQVGPDDLIHYGMIPEFVGRFPVVATL
CHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCHHHHHHCCCHHHHCCCCEEEEE
DDLSVEDLKRIMLEPKNAVIKQYQKLLEIEGITLQFTEDALTAIAKEALKRGTGARAIKS
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCHHHHHH
VIESVMLDIMFEAPSMENVEKIIMTKDVIEGRAKPEIITRESA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEECCCC
>Mature Secondary Structure 
PFERKCSFCGRPASQVKKLISGAEGYICDECVELFHDILKEDTKVRREPGKKLPKPAEI
CCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KAILDQYVIGQEKAKKTISVAVYNHYKRVFIGSDDIEVEKSNIMLIGPTGSGKTLIARTL
HHHHHHHHHCHHHHHHHEEHEEECCCEEEEECCCCCEEEECCEEEEECCCCCHHHHHHHH
AKILDVPFAIADATPLTEAGYVGEDVENVILRLLQAANFDVERAQYGIIYIDEIDKITRK
HHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEECHHHHHHC
TSNPSITRDVSGEGVQQALLKIVEGTIANVPPQGGRKHPYQEFIKIDTTNILFIVGGAFD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCEEEEEECCCCC
GLDEIIKERILTSTMGFGAEVKGKDSYRLGEILAQVGPDDLIHYGMIPEFVGRFPVVATL
CHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCHHHHHHCCCHHHHCCCCEEEEE
DDLSVEDLKRIMLEPKNAVIKQYQKLLEIEGITLQFTEDALTAIAKEALKRGTGARAIKS
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCHHHHHH
VIESVMLDIMFEAPSMENVEKIIMTKDVIEGRAKPEIITRESA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]