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The map label for this gene is nuoE [H]

Identifier: 239616591

GI number: 239616591

Start: 205002

End: 205505

Strand: Direct

Name: nuoE [H]

Synonym: Kole_0183

Alternate gene names: 239616591

Gene position: 205002-205505 (Clockwise)

Preceding gene: 239616590

Following gene: 239616592

Centisome position: 8.9

GC content: 43.45

Gene sequence:

>504_bases
ATGGCTGTTGAGGAAGTGAAAGAAACGGTCGCCAGTATATATGAAAAAGTAATGAGCGAAAGCCTTGAAAAGGGTGACAT
CCTGATAAATACGCTTCATGCCATTCAGGATTATTATGGAAATTACATACCATTGGAAGCTACCGAAGCTTTGAGAGACA
TTATGGGAATCCCTCTGTCAAAGATCTACGAGGTCCTCACCTTCTACACCATGTTCTCAACAGAGAAACGCGGTAAGTAC
ATTATACGCGTTTGCAAGAGCCTTCCATGCCACGTAACCGGTGGAGAGAAGGTTGTAGAAGCACTGAAAGATACCCTTGG
TATCGATTTCGGTAACACGACCGAAGACGGTTTGTTTACACTTGAAGAAAGCAGCTGTCTGGGGTTGTGCGGTGTGTCCC
CGGTAATGATGATCAATGATGAAGCTTACGGAAATCTGACTCCCGATAAAGTAGAAAAAATCATCAATGAAATACGCGAA
AAGGAAAGAAGTGATGCCAGATGA

Upstream 100 bases:

>100_bases
TCGACGCTATAAAGAAGGTTTCTCCATAAATTCTCCTGCAAAACCCCACCGGGGTTTTGCAGTTTTTAGTTATTAATAGT
GGGTGAAAGGAGGAGCATGA

Downstream 100 bases:

>100_bases
AACCGATTACTGTGCTGGTCTCGGTGGATTCAAACAGCGTTTTGCTCGGTGCGAGGCACTTCAAGAATCATCTTGTGGGT
CTGGTGAAGAAATATAACCT

Product: NADH dehydrogenase (ubiquinone) 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MAVEEVKETVASIYEKVMSESLEKGDILINTLHAIQDYYGNYIPLEATEALRDIMGIPLSKIYEVLTFYTMFSTEKRGKY
IIRVCKSLPCHVTGGEKVVEALKDTLGIDFGNTTEDGLFTLEESSCLGLCGVSPVMMINDEAYGNLTPDKVEKIINEIRE
KERSDAR

Sequences:

>Translated_167_residues
MAVEEVKETVASIYEKVMSESLEKGDILINTLHAIQDYYGNYIPLEATEALRDIMGIPLSKIYEVLTFYTMFSTEKRGKY
IIRVCKSLPCHVTGGEKVVEALKDTLGIDFGNTTEDGLFTLEESSCLGLCGVSPVMMINDEAYGNLTPDKVEKIINEIRE
KERSDAR
>Mature_166_residues
AVEEVKETVASIYEKVMSESLEKGDILINTLHAIQDYYGNYIPLEATEALRDIMGIPLSKIYEVLTFYTMFSTEKRGKYI
IRVCKSLPCHVTGGEKVVEALKDTLGIDFGNTTEDGLFTLEESSCLGLCGVSPVMMINDEAYGNLTPDKVEKIINEIREK
ERSDAR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=118, Percent_Identity=40.6779661016949, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788621, Length=127, Percent_Identity=37.007874015748, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561328, Length=144, Percent_Identity=38.8888888888889, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859877, Length=152, Percent_Identity=38.1578947368421, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355353, Length=139, Percent_Identity=35.2517985611511, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18700; Mature: 18568

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVEEVKETVASIYEKVMSESLEKGDILINTLHAIQDYYGNYIPLEATEALRDIMGIPLS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHH
KIYEVLTFYTMFSTEKRGKYIIRVCKSLPCHVTGGEKVVEALKDTLGIDFGNTTEDGLFT
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEE
LEESSCLGLCGVSPVMMINDEAYGNLTPDKVEKIINEIREKERSDAR
ECCCCEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVEEVKETVASIYEKVMSESLEKGDILINTLHAIQDYYGNYIPLEATEALRDIMGIPLS
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHH
KIYEVLTFYTMFSTEKRGKYIIRVCKSLPCHVTGGEKVVEALKDTLGIDFGNTTEDGLFT
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEE
LEESSCLGLCGVSPVMMINDEAYGNLTPDKVEKIINEIREKERSDAR
ECCCCEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]