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The map label for this gene is argC

Identifier: 239616504

GI number: 239616504

Start: 108872

End: 109891

Strand: Direct

Name: argC

Synonym: Kole_0094

Alternate gene names: 239616504

Gene position: 108872-109891 (Clockwise)

Preceding gene: 239616503

Following gene: 239616505

Centisome position: 4.73

GC content: 41.57

Gene sequence:

>1020_bases
ATGATAAGGGTTGGAATAATAGGTGCAACTGGCTACACAGGATTGGAACTCGTGAGAATACTCACCAATCACCCTGATGT
TAAAATAACCTTTCTTTCTTCCAGGAGTTTTGCGGGGAAAAAATTGAATGACGTTTATCCCTTCTCGCTAAAAAATGAAA
CCCTCGAAGAGATAGACCCTGAAAAAATCTCGAAAAATTGTGATGTTGTATTCACGGCACTTCCAGCCGGTGTTTCCTAT
GAAATTGCCAGAAAATTGAAAGATGTTCGAATAATCGACCTTGGAGCTGATTTTAGATTCGATGACCCTGCCGTTTACGA
GGAATGGTATTCTAAAAAGCTACCTGATTATGATCCTACTGAAAGGGTTTACGGCTTAACAGAGCTGTACAGGGAAAAGA
TAAAGAATGCCAGATTCGTTGGAAATCCAGGCTGTTATCCTACGAGTGTTTTGCTTGCAACGGCTCCACTATTGAAGAAC
GGTTCACTGGATGAAGAAACAATCATTGTGGATTCAAAATCCGGGGTTTCAGGTGCCGGAAAAAAGGAATCGATAGATTA
CTCATTTTCTGAACTTAGCGGGAGTCTGAAGGCGTATAACGTGTCAAAGCACAGGCATGTCCCGGAAATGGAGCAGGAAA
TGTCTAAACTTTGCGGTAAAAGACTAAAACTTGTCTTCACTCCACACCTCGTCCCGATGGTTAGAGGAATCCTTTCGACG
ATATATGTGAAAACGGATCTATCTTTAGATGAGGTTTATGAATTATACCGGGAATACTATGGAAAAGAGAAATTCATCCA
CGTCCTTCAACCAGGCGTTTATCCTTCAACAAAATGGACTTACGGTTCAAATCACGCTTTCATATCTATGGCAAAAGACG
ATAGAACCGACACGCTCATCCTGATAAGTGTGATAGACAACCTCGTAAAAGGAGCGTCCGGACAGGCTGTTCAAAACATG
AACGTCATGTTTTCCTTAGCCGAAGATGCAGGGCTTTCTTTCAATCCAATTTATCCATAA

Upstream 100 bases:

>100_bases
AGGTCCTTGCGACTCAAAAGGTTTATGAAATGGTTAAAAAAGGTACCCCGTTTAGGGACGCTTACAGAAAAATAGCCCAA
AGTTACGGAGGCGAGAAGAA

Downstream 100 bases:

>100_bases
AAGGAGGTCGAAAAAATGAACATACCAAAAGGCTTTAAATTTGTAGGACTACATTGTGGGATAAAGAGAAAAAGAAAAGA
TTTAGGAATAATATACTCAG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIRVGIIGATGYTGLELVRILTNHPDVKITFLSSRSFAGKKLNDVYPFSLKNETLEEIDPEKISKNCDVVFTALPAGVSY
EIARKLKDVRIIDLGADFRFDDPAVYEEWYSKKLPDYDPTERVYGLTELYREKIKNARFVGNPGCYPTSVLLATAPLLKN
GSLDEETIIVDSKSGVSGAGKKESIDYSFSELSGSLKAYNVSKHRHVPEMEQEMSKLCGKRLKLVFTPHLVPMVRGILST
IYVKTDLSLDEVYELYREYYGKEKFIHVLQPGVYPSTKWTYGSNHAFISMAKDDRTDTLILISVIDNLVKGASGQAVQNM
NVMFSLAEDAGLSFNPIYP

Sequences:

>Translated_339_residues
MIRVGIIGATGYTGLELVRILTNHPDVKITFLSSRSFAGKKLNDVYPFSLKNETLEEIDPEKISKNCDVVFTALPAGVSY
EIARKLKDVRIIDLGADFRFDDPAVYEEWYSKKLPDYDPTERVYGLTELYREKIKNARFVGNPGCYPTSVLLATAPLLKN
GSLDEETIIVDSKSGVSGAGKKESIDYSFSELSGSLKAYNVSKHRHVPEMEQEMSKLCGKRLKLVFTPHLVPMVRGILST
IYVKTDLSLDEVYELYREYYGKEKFIHVLQPGVYPSTKWTYGSNHAFISMAKDDRTDTLILISVIDNLVKGASGQAVQNM
NVMFSLAEDAGLSFNPIYP
>Mature_339_residues
MIRVGIIGATGYTGLELVRILTNHPDVKITFLSSRSFAGKKLNDVYPFSLKNETLEEIDPEKISKNCDVVFTALPAGVSY
EIARKLKDVRIIDLGADFRFDDPAVYEEWYSKKLPDYDPTERVYGLTELYREKIKNARFVGNPGCYPTSVLLATAPLLKN
GSLDEETIIVDSKSGVSGAGKKESIDYSFSELSGSLKAYNVSKHRHVPEMEQEMSKLCGKRLKLVFTPHLVPMVRGILST
IYVKTDLSLDEVYELYREYYGKEKFIHVLQPGVYPSTKWTYGSNHAFISMAKDDRTDTLILISVIDNLVKGASGQAVQNM
NVMFSLAEDAGLSFNPIYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=346, Percent_Identity=34.393063583815, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320913, Length=348, Percent_Identity=35.3448275862069, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_KOSOT (C5CHW7)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002939826.1
- ProteinModelPortal:   C5CHW7
- GeneID:   7967512
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_0094
- ProtClustDB:   PRK00436
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37999; Mature: 37999

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVGIIGATGYTGLELVRILTNHPDVKITFLSSRSFAGKKLNDVYPFSLKNETLEEIDP
CEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCH
EKISKNCDVVFTALPAGVSYEIARKLKDVRIIDLGADFRFDDPAVYEEWYSKKLPDYDPT
HHHCCCCCEEEEECCCCCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCHH
ERVYGLTELYREKIKNARFVGNPGCYPTSVLLATAPLLKNGSLDEETIIVDSKSGVSGAG
HHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC
KKESIDYSFSELSGSLKAYNVSKHRHVPEMEQEMSKLCGKRLKLVFTPHLVPMVRGILST
CCCCCCCCHHHHCCCEEEEECHHHCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHH
IYVKTDLSLDEVYELYREYYGKEKFIHVLQPGVYPSTKWTYGSNHAFISMAKDDRTDTLI
EEEEECCCHHHHHHHHHHHCCHHHEEHHHCCCCCCCCCEECCCCCEEEEECCCCCCCCEE
LISVIDNLVKGASGQAVQNMNVMFSLAEDAGLSFNPIYP
HHHHHHHHHCCCCCCCEECCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MIRVGIIGATGYTGLELVRILTNHPDVKITFLSSRSFAGKKLNDVYPFSLKNETLEEIDP
CEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCH
EKISKNCDVVFTALPAGVSYEIARKLKDVRIIDLGADFRFDDPAVYEEWYSKKLPDYDPT
HHHCCCCCEEEEECCCCCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCHH
ERVYGLTELYREKIKNARFVGNPGCYPTSVLLATAPLLKNGSLDEETIIVDSKSGVSGAG
HHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC
KKESIDYSFSELSGSLKAYNVSKHRHVPEMEQEMSKLCGKRLKLVFTPHLVPMVRGILST
CCCCCCCCHHHHCCCEEEEECHHHCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHH
IYVKTDLSLDEVYELYREYYGKEKFIHVLQPGVYPSTKWTYGSNHAFISMAKDDRTDTLI
EEEEECCCHHHHHHHHHHHCCHHHEEHHHCCCCCCCCCEECCCCCEEEEECCCCCCCCEE
LISVIDNLVKGASGQAVQNMNVMFSLAEDAGLSFNPIYP
HHHHHHHHHCCCCCCCEECCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA