Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 238925484

GI number: 238925484

Start: 2991280

End: 2992248

Strand: Reverse

Name: fabH [H]

Synonym: EUBREC_3140

Alternate gene names: 238925484

Gene position: 2992248-2991280 (Counterclockwise)

Preceding gene: 238925485

Following gene: 238925483

Centisome position: 86.74

GC content: 48.5

Gene sequence:

>969_bases
ATGAAGATAGTTGGAACAGGAAGCTGCCTGCCACAGAGAGTGGTCTCAAACGATGACCTGGCAGCCATAATGGACACATC
TGACGAGTGGATCAGCTCGCGTACAGGAATAAGAAACAGACACATTGCAACGACTGAGACAACCACCTCACTTGCCTGTG
ATGCAGTAAAAAGTGCGCTGCAGGATGCGGGGATTGACGGAAGTGAGATAGACTTGATAATAGCGGCAAGCGTATCCACA
GACAAAATCGTTCCATCGCTCGCATGTCAGATTCAGGCTGAGATAGGTGCAGGCAGTGCAGTGGCATTTGACATAAATGC
CGCATGCTCAGGCTTTTTATTCGGGCTTGCCACAGCGGATGCATATTTTAAGACCGGCAGGTTTCACAAGGCAGTCGTAG
TGGGAGCAGAGGTTCTTTCAAAAATAATGGACTGGAATGACAGAAGCACCTGTGTACTTTTCGGAGACGGAGCAGGAGCA
GCCGTTGTGACAGACGAGGGCGATGCTTTTAAGGGCTTTGTACAGGGCTCGGACGGAAAAGGCGGTGAGGCGCTTGACGG
AGACAACCGTCCTGTAGTCAATCCGTTTACCGACAATGGAAAGCAGTCTGCACTCGGTGGCTATGTCACTATGGACGGTC
CTGCTGTATACAAGTTTGCGGTAAAGACAGTGCCAAAGGCTATAAATGAGCTGCTTGATGAAATCGGCTGGAGCGTAGAT
GATGTGGATGTCTATGTGTTGCATCAGGCCAATATACGTATTATTGAGTCGGTTGCCAAGAGGCTTAAGCAGCCTATGGA
CAAATTCCCGACCAATTTACAGCATTGTGGAAATATTTCTGCGGCAAGTGTGCCGATTTTGCTTGATAAAGTCCGCAAAG
ATGGTATGATAAAGCATGAGGAAAAAATAATTTTATCAGGCTTTGGAGCAGGACTTACATGGGGAGCCTGCGCCATAGAG
TGGCAATAG

Upstream 100 bases:

>100_bases
GAAGAAATTCTTGGAAAAAGAAAGCAAATTGACAAAGGACCAGCTCTTGGAGGAAAGATACAAGCGTTTCCGCAAGTTCT
AGTCCCGGAAAGGAAATTCT

Downstream 100 bases:

>100_bases
AAAGAGGTATTTATGACGGCAGATGAAACTTTAAATGAATTATTGGTGTGTCTGTTCAAGGATTTGACAGAGATAGAGGG
CAGATGTCTGATAACAGACG

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKIVGTGSCLPQRVVSNDDLAAIMDTSDEWISSRTGIRNRHIATTETTTSLACDAVKSALQDAGIDGSEIDLIIAASVST
DKIVPSLACQIQAEIGAGSAVAFDINAACSGFLFGLATADAYFKTGRFHKAVVVGAEVLSKIMDWNDRSTCVLFGDGAGA
AVVTDEGDAFKGFVQGSDGKGGEALDGDNRPVVNPFTDNGKQSALGGYVTMDGPAVYKFAVKTVPKAINELLDEIGWSVD
DVDVYVLHQANIRIIESVAKRLKQPMDKFPTNLQHCGNISAASVPILLDKVRKDGMIKHEEKIILSGFGAGLTWGACAIE
WQ

Sequences:

>Translated_322_residues
MKIVGTGSCLPQRVVSNDDLAAIMDTSDEWISSRTGIRNRHIATTETTTSLACDAVKSALQDAGIDGSEIDLIIAASVST
DKIVPSLACQIQAEIGAGSAVAFDINAACSGFLFGLATADAYFKTGRFHKAVVVGAEVLSKIMDWNDRSTCVLFGDGAGA
AVVTDEGDAFKGFVQGSDGKGGEALDGDNRPVVNPFTDNGKQSALGGYVTMDGPAVYKFAVKTVPKAINELLDEIGWSVD
DVDVYVLHQANIRIIESVAKRLKQPMDKFPTNLQHCGNISAASVPILLDKVRKDGMIKHEEKIILSGFGAGLTWGACAIE
WQ
>Mature_322_residues
MKIVGTGSCLPQRVVSNDDLAAIMDTSDEWISSRTGIRNRHIATTETTTSLACDAVKSALQDAGIDGSEIDLIIAASVST
DKIVPSLACQIQAEIGAGSAVAFDINAACSGFLFGLATADAYFKTGRFHKAVVVGAEVLSKIMDWNDRSTCVLFGDGAGA
AVVTDEGDAFKGFVQGSDGKGGEALDGDNRPVVNPFTDNGKQSALGGYVTMDGPAVYKFAVKTVPKAINELLDEIGWSVD
DVDVYVLHQANIRIIESVAKRLKQPMDKFPTNLQHCGNISAASVPILLDKVRKDGMIKHEEKIILSGFGAGLTWGACAIE
WQ

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=42.4148606811146, Blast_Score=239, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34044; Mature: 34044

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVGTGSCLPQRVVSNDDLAAIMDTSDEWISSRTGIRNRHIATTETTTSLACDAVKSAL
CEEEECCCCCHHHHCCCCCEEEEECCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHH
QDAGIDGSEIDLIIAASVSTDKIVPSLACQIQAEIGAGSAVAFDINAACSGFLFGLATAD
HHCCCCCCCEEEEEEECCCCCHHHHHHHEEEEEECCCCCEEEEECCHHHHHHHHHHHHHH
AYFKTGRFHKAVVVGAEVLSKIMDWNDRSTCVLFGDGAGAAVVTDEGDAFKGFVQGSDGK
HHHHCCCCHHHEEHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCEEEEEECCCCC
GGEALDGDNRPVVNPFTDNGKQSALGGYVTMDGPAVYKFAVKTVPKAINELLDEIGWSVD
CCCCCCCCCCCEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DVDVYVLHQANIRIIESVAKRLKQPMDKFPTNLQHCGNISAASVPILLDKVRKDGMIKHE
CEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCC
EKIILSGFGAGLTWGACAIEWQ
CEEEEEECCCCCCCCEEEEECC
>Mature Secondary Structure
MKIVGTGSCLPQRVVSNDDLAAIMDTSDEWISSRTGIRNRHIATTETTTSLACDAVKSAL
CEEEECCCCCHHHHCCCCCEEEEECCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHH
QDAGIDGSEIDLIIAASVSTDKIVPSLACQIQAEIGAGSAVAFDINAACSGFLFGLATAD
HHCCCCCCCEEEEEEECCCCCHHHHHHHEEEEEECCCCCEEEEECCHHHHHHHHHHHHHH
AYFKTGRFHKAVVVGAEVLSKIMDWNDRSTCVLFGDGAGAAVVTDEGDAFKGFVQGSDGK
HHHHCCCCHHHEEHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCEEEEEECCCCC
GGEALDGDNRPVVNPFTDNGKQSALGGYVTMDGPAVYKFAVKTVPKAINELLDEIGWSVD
CCCCCCCCCCCEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DVDVYVLHQANIRIIESVAKRLKQPMDKFPTNLQHCGNISAASVPILLDKVRKDGMIKHE
CEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCC
EKIILSGFGAGLTWGACAIEWQ
CEEEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]