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The map label for this gene is accD

Identifier: 238925485

GI number: 238925485

Start: 2992267

End: 2994036

Strand: Reverse

Name: accD

Synonym: EUBREC_3141

Alternate gene names: 238925485

Gene position: 2994036-2992267 (Counterclockwise)

Preceding gene: 238925486

Following gene: 238925484

Centisome position: 86.79

GC content: 46.72

Gene sequence:

>1770_bases
ATGATGAAGTTATTCAAGAAGAAAGATAAAAATATAGAGGCTGAAGAGACTTTAGCAAAGAACGCTGAGAGCGAAAAAAC
AGCCGCAGATGGCAAAAATGCCGGTGTAGCACAGGAAACAAAAGAGGATGCCCCTGAGACAATCGTTTGTCCCAAGTGTG
GCAAGACTGTGCTCAAATCAGTTGTAAAACAGCACAAATACGTCTGCTATGAGTGTAATTATTATTTCCGTGTGCGTGCT
AAAAACAGAATCAGAATGGTTTCCGACAAGGAAGCATTTGAGCCATGGTTTACAGAGCTTACAACAGGAAATCCTCTCAA
TTTCCCTGAGTATGAGGAGAAAATTGCAAAGACTCAGGAGAAAACAGGACTTTCTGAGGGTATTGTCATCGGTAAGACAA
AGATTTACGGCGAGGAGACAGTGCTTGGTGTAATTGATTCAAGATTTATGATGGGAAGCATGGGCCATGTGGTTGGTGAG
AAAATCACAAGCGCATTTGAGCGTGCCACAGAGGAAAGACTTCCTGTTATATTATTCTGCTGTTCAGGCGGTGCCAGAAT
GCAGGAGGGTATCATTTCGCTGATGCAGATGGCAAAGACCTCAGCCGCAGCAAAACGTCATTCAGAGGCAGGACTTTTAT
ATGTGCCTGTACTCACAGATCCTACAACAGGTGGTGTGACAGCCAGCTTTGCAATGCTTGGAGACATCATTCTTGCAGAG
CCAAAGGCACTTATCGGCTTTGCGGGTCCTCGTGTTATCGAGCAGACCATCGGACAGAAGCTGCCTGAGGGCTTCCAGAG
GGCAGAGTTCCAGCTTGAGCACGGCTTTGTAGATATGATAGTTGAGCGTGAGGATTTAAAGAAGACTCTTTACAAGATTT
TACGTGCTCACAGACCTACCACAGGCTATGCCAATTTTGACCCGCTTCACTCAGACGACAATTACGAGCCGACAGAGCTT
ATGAAGGAGCGCGAGGCAAAGGCTAAGCCATTTAAGGTATGGGACAAGGTCAGCGCCGCAAGACAGATTAAGAGACTTGC
ATCGGTTGACTATATGGACTATATCTTTGATGAGTTTATGGAGCTGCACGGAGACAGATATTTCCGCGATGACCCGGCTA
TCGTAGGCGGAATCGCATATTTAGACGGCCAGCCGGTTACAGTTATCGGTGTCCACAAGGGAAAAGACCTTGAGGACTGC
GCAAAGAGAAACTATGGTATGCCATCACCGGAGGGCTACCGCAAGGCACTGCGCCTCATGAAGCAGGCAGAGAAATTCAA
CCGTCCGATCATAACCTTTGTCAATACATCAGGAGCTTATCCGGGAATGGAAGCAGAGGAAAACGGACAGGGTGAGGCAA
TCGCAAGAAACCTTTATGAGATGAGCGGCATCAAGGTGCCAATCCTTTGTCTCATGATAGGAGAAGGCGGAAGCGGCGGA
GCTTTAGCTCTTTCTGTAGGAAATGAAGTGTGGATGATGGAAAATGCCACATACTCAATCCTTTCGCCAGAAGGCTTTGC
ATCTATCCTCTGGAAGGACGGAAAGCGTGCAAAGGAAGCCGCAGAGGTAATGAAGATTACAGCACACGACTTAAAGGAGC
TTGATGTCGTGGATGATATAATACCTGAGTTTGGCGGAGCCGACGAGGATGCCCTTTCATCAATCGGAAACTACATGAAG
GGCAACATGAAGAAATTCTTGGAAAAAGAAAGCAAATTGACAAAGGACCAGCTCTTGGAGGAAAGATACAAGCGTTTCCG
CAAGTTCTAG

Upstream 100 bases:

>100_bases
AGGGTCCTATCGGTGTGGGCAAGGCTGTTGCCAGGGTAAATGGCAAGGTTGCCTGTATGGCGGAGCTTACATTTGCAATA
GGTTAATTGCATAAGGAGAC

Downstream 100 bases:

>100_bases
TCCCGGAAAGGAAATTCTATGAAGATAGTTGGAACAGGAAGCTGCCTGCCACAGAGAGTGGTCTCAAACGATGACCTGGC
AGCCATAATGGACACATCTG

Product: acetyl-coA carboxylase carboxyl transferase subunit beta/alpha

Products: NA

Alternate protein names: ACCase subunits beta/alpha; Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MMKLFKKKDKNIEAEETLAKNAESEKTAADGKNAGVAQETKEDAPETIVCPKCGKTVLKSVVKQHKYVCYECNYYFRVRA
KNRIRMVSDKEAFEPWFTELTTGNPLNFPEYEEKIAKTQEKTGLSEGIVIGKTKIYGEETVLGVIDSRFMMGSMGHVVGE
KITSAFERATEERLPVILFCCSGGARMQEGIISLMQMAKTSAAAKRHSEAGLLYVPVLTDPTTGGVTASFAMLGDIILAE
PKALIGFAGPRVIEQTIGQKLPEGFQRAEFQLEHGFVDMIVEREDLKKTLYKILRAHRPTTGYANFDPLHSDDNYEPTEL
MKEREAKAKPFKVWDKVSAARQIKRLASVDYMDYIFDEFMELHGDRYFRDDPAIVGGIAYLDGQPVTVIGVHKGKDLEDC
AKRNYGMPSPEGYRKALRLMKQAEKFNRPIITFVNTSGAYPGMEAEENGQGEAIARNLYEMSGIKVPILCLMIGEGGSGG
ALALSVGNEVWMMENATYSILSPEGFASILWKDGKRAKEAAEVMKITAHDLKELDVVDDIIPEFGGADEDALSSIGNYMK
GNMKKFLEKESKLTKDQLLEERYKRFRKF

Sequences:

>Translated_589_residues
MMKLFKKKDKNIEAEETLAKNAESEKTAADGKNAGVAQETKEDAPETIVCPKCGKTVLKSVVKQHKYVCYECNYYFRVRA
KNRIRMVSDKEAFEPWFTELTTGNPLNFPEYEEKIAKTQEKTGLSEGIVIGKTKIYGEETVLGVIDSRFMMGSMGHVVGE
KITSAFERATEERLPVILFCCSGGARMQEGIISLMQMAKTSAAAKRHSEAGLLYVPVLTDPTTGGVTASFAMLGDIILAE
PKALIGFAGPRVIEQTIGQKLPEGFQRAEFQLEHGFVDMIVEREDLKKTLYKILRAHRPTTGYANFDPLHSDDNYEPTEL
MKEREAKAKPFKVWDKVSAARQIKRLASVDYMDYIFDEFMELHGDRYFRDDPAIVGGIAYLDGQPVTVIGVHKGKDLEDC
AKRNYGMPSPEGYRKALRLMKQAEKFNRPIITFVNTSGAYPGMEAEENGQGEAIARNLYEMSGIKVPILCLMIGEGGSGG
ALALSVGNEVWMMENATYSILSPEGFASILWKDGKRAKEAAEVMKITAHDLKELDVVDDIIPEFGGADEDALSSIGNYMK
GNMKKFLEKESKLTKDQLLEERYKRFRKF
>Mature_589_residues
MMKLFKKKDKNIEAEETLAKNAESEKTAADGKNAGVAQETKEDAPETIVCPKCGKTVLKSVVKQHKYVCYECNYYFRVRA
KNRIRMVSDKEAFEPWFTELTTGNPLNFPEYEEKIAKTQEKTGLSEGIVIGKTKIYGEETVLGVIDSRFMMGSMGHVVGE
KITSAFERATEERLPVILFCCSGGARMQEGIISLMQMAKTSAAAKRHSEAGLLYVPVLTDPTTGGVTASFAMLGDIILAE
PKALIGFAGPRVIEQTIGQKLPEGFQRAEFQLEHGFVDMIVEREDLKKTLYKILRAHRPTTGYANFDPLHSDDNYEPTEL
MKEREAKAKPFKVWDKVSAARQIKRLASVDYMDYIFDEFMELHGDRYFRDDPAIVGGIAYLDGQPVTVIGVHKGKDLEDC
AKRNYGMPSPEGYRKALRLMKQAEKFNRPIITFVNTSGAYPGMEAEENGQGEAIARNLYEMSGIKVPILCLMIGEGGSGG
ALALSVGNEVWMMENATYSILSPEGFASILWKDGKRAKEAAEVMKITAHDLKELDVVDDIIPEFGGADEDALSSIGNYMK
GNMKKFLEKESKLTKDQLLEERYKRFRKF

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=257, Percent_Identity=52.5291828793774, Blast_Score=268, Evalue=9e-73,
Organism=Escherichia coli, GI1788655, Length=248, Percent_Identity=47.5806451612903, Blast_Score=237, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCDA_EUBR3 (C4Z8P1)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002939002.1
- GeneID:   7965159
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_3141
- ProtClustDB:   CLSK911920
- HAMAP:   MF_00823
- HAMAP:   MF_01395
- InterPro:   IPR001095
- InterPro:   IPR000438
- InterPro:   IPR011763
- InterPro:   IPR011762
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 65834; Mature: 65834

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50989 COA_CT_CTER; PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLFKKKDKNIEAEETLAKNAESEKTAADGKNAGVAQETKEDAPETIVCPKCGKTVLKS
CCCCHHHCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCHHHHHCCCCEEECCCCCHHHHHH
VVKQHKYVCYECNYYFRVRAKNRIRMVSDKEAFEPWFTELTTGNPLNFPEYEEKIAKTQE
HHHHCCEEEEECCEEEEEEECCCEEEECCHHHHCHHHHHCCCCCCCCCCHHHHHHHHHHH
KTGLSEGIVIGKTKIYGEETVLGVIDSRFMMGSMGHVVGEKITSAFERATEERLPVILFC
HCCCCCCEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
CSGGARMQEGIISLMQMAKTSAAAKRHSEAGLLYVPVLTDPTTGGVTASFAMLGDIILAE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCC
PKALIGFAGPRVIEQTIGQKLPEGFQRAEFQLEHGFVDMIVEREDLKKTLYKILRAHRPT
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
TGYANFDPLHSDDNYEPTELMKEREAKAKPFKVWDKVSAARQIKRLASVDYMDYIFDEFM
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELHGDRYFRDDPAIVGGIAYLDGQPVTVIGVHKGKDLEDCAKRNYGMPSPEGYRKALRLM
HHCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHH
KQAEKFNRPIITFVNTSGAYPGMEAEENGQGEAIARNLYEMSGIKVPILCLMIGEGGSGG
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
ALALSVGNEVWMMENATYSILSPEGFASILWKDGKRAKEAAEVMKITAHDLKELDVVDDI
EEEEEECCEEEEEECCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IPEFGGADEDALSSIGNYMKGNMKKFLEKESKLTKDQLLEERYKRFRKF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKLFKKKDKNIEAEETLAKNAESEKTAADGKNAGVAQETKEDAPETIVCPKCGKTVLKS
CCCCHHHCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCHHHHHCCCCEEECCCCCHHHHHH
VVKQHKYVCYECNYYFRVRAKNRIRMVSDKEAFEPWFTELTTGNPLNFPEYEEKIAKTQE
HHHHCCEEEEECCEEEEEEECCCEEEECCHHHHCHHHHHCCCCCCCCCCHHHHHHHHHHH
KTGLSEGIVIGKTKIYGEETVLGVIDSRFMMGSMGHVVGEKITSAFERATEERLPVILFC
HCCCCCCEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
CSGGARMQEGIISLMQMAKTSAAAKRHSEAGLLYVPVLTDPTTGGVTASFAMLGDIILAE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCC
PKALIGFAGPRVIEQTIGQKLPEGFQRAEFQLEHGFVDMIVEREDLKKTLYKILRAHRPT
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
TGYANFDPLHSDDNYEPTELMKEREAKAKPFKVWDKVSAARQIKRLASVDYMDYIFDEFM
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELHGDRYFRDDPAIVGGIAYLDGQPVTVIGVHKGKDLEDCAKRNYGMPSPEGYRKALRLM
HHCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHH
KQAEKFNRPIITFVNTSGAYPGMEAEENGQGEAIARNLYEMSGIKVPILCLMIGEGGSGG
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
ALALSVGNEVWMMENATYSILSPEGFASILWKDGKRAKEAAEVMKITAHDLKELDVVDDI
EEEEEECCEEEEEECCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IPEFGGADEDALSSIGNYMKGNMKKFLEKESKLTKDQLLEERYKRFRKF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA