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The map label for this gene is bceR [H]

Identifier: 238925431

GI number: 238925431

Start: 2951006

End: 2951677

Strand: Reverse

Name: bceR [H]

Synonym: EUBREC_3086

Alternate gene names: 238925431

Gene position: 2951677-2951006 (Counterclockwise)

Preceding gene: 238925432

Following gene: 238925430

Centisome position: 85.56

GC content: 43.01

Gene sequence:

>672_bases
ATGTATAGAATATTTTTGGTTGAGGATGACGAGACCATAGCAAAGCTTGTCAGAAGACATTTGGAAAAATGGGATTATGA
TGTGCATGTGGTGCAGAAATTTGATGCTGTAATGTCAGAATTTGCATCATTTGATCCGCAGCTTGTGCTTATGGATATCG
GTCTGCCGTTTTACAATGGGTATCACTGGTGTACGGAAATCAGAAGGGTATCAAAGGTTCCTGTGGTTTTCCTGTCATCC
GCTGCTGATAATATGAATATAGTGATGGCAGTCAGTATGGGGGCAGACGACTTTATAGCAAAGCCGTTTGACCTCGATGT
GCTGACCGTAAAGATACAGGCTATCATCAGGCGCTGCTATGATTTTGGCGCAAATAACAGTGTTTTGGAGCATAATGGCG
CCATGCTCAATATATCTGATGCCACCATAACCTATGACGACAAAAGGCTCGAGCTTACAAAGAATGAGCTCAAAATATTG
CAGACACTTTTTGACAATAAAGAAAGGATTGTATCACGCAGCCTTCTAATGGAAAAGCTGTGGGAGAGTGATGCGTATGT
GGACGAGAATACACTTTCGGTGAATGTCAACAGGCTGCGTAAAAAGCTGGATTCTATAGGGCTTGAGAGCTTTATTGTCA
CAAAAAAGGGGCTTGGGTACAGGCTGGGGTGA

Upstream 100 bases:

>100_bases
TGATTCCAAAGGCACAGCTCAAGCCGGATTTACTTCGTATGAAGGCATCACAGCTCATCATCGATGCGGCTGAGATTATC
ATGGAAGAAAGCGAAAAATA

Downstream 100 bases:

>100_bases
GAGGTCATGGCAAAAATACAAAACAAACCGCATCTGACAAATTTTATAAAACAAAACTATATATGGATTTTGATGATAGT
CACAATGACCTGTATCCATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MYRIFLVEDDETIAKLVRRHLEKWDYDVHVVQKFDAVMSEFASFDPQLVLMDIGLPFYNGYHWCTEIRRVSKVPVVFLSS
AADNMNIVMAVSMGADDFIAKPFDLDVLTVKIQAIIRRCYDFGANNSVLEHNGAMLNISDATITYDDKRLELTKNELKIL
QTLFDNKERIVSRSLLMEKLWESDAYVDENTLSVNVNRLRKKLDSIGLESFIVTKKGLGYRLG

Sequences:

>Translated_223_residues
MYRIFLVEDDETIAKLVRRHLEKWDYDVHVVQKFDAVMSEFASFDPQLVLMDIGLPFYNGYHWCTEIRRVSKVPVVFLSS
AADNMNIVMAVSMGADDFIAKPFDLDVLTVKIQAIIRRCYDFGANNSVLEHNGAMLNISDATITYDDKRLELTKNELKIL
QTLFDNKERIVSRSLLMEKLWESDAYVDENTLSVNVNRLRKKLDSIGLESFIVTKKGLGYRLG
>Mature_223_residues
MYRIFLVEDDETIAKLVRRHLEKWDYDVHVVQKFDAVMSEFASFDPQLVLMDIGLPFYNGYHWCTEIRRVSKVPVVFLSS
AADNMNIVMAVSMGADDFIAKPFDLDVLTVKIQAIIRRCYDFGANNSVLEHNGAMLNISDATITYDDKRLELTKNELKIL
QTLFDNKERIVSRSLLMEKLWESDAYVDENTLSVNVNRLRKKLDSIGLESFIVTKKGLGYRLG

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=30.4932735426009, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=28.6363636363636, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=25.6756756756757, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=32.7433628318584, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=27.0642201834862, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=28.1938325991189, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=26.6375545851528, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=26.4957264957265, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=27.8026905829596, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=25.4464285714286, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=27.3127753303965, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=27.1493212669683, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=29.4642857142857, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25684; Mature: 25684

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIFLVEDDETIAKLVRRHLEKWDYDVHVVQKFDAVMSEFASFDPQLVLMDIGLPFYNG
CEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
YHWCTEIRRVSKVPVVFLSSAADNMNIVMAVSMGADDFIAKPFDLDVLTVKIQAIIRRCY
HHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHH
DFGANNSVLEHNGAMLNISDATITYDDKRLELTKNELKILQTLFDNKERIVSRSLLMEKL
HCCCCCCEEECCCCEEEECCCEEEECCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHH
WESDAYVDENTLSVNVNRLRKKLDSIGLESFIVTKKGLGYRLG
HCCCCCCCCCEEEEEHHHHHHHHHHCCCHHEEEECCCCCCCCC
>Mature Secondary Structure
MYRIFLVEDDETIAKLVRRHLEKWDYDVHVVQKFDAVMSEFASFDPQLVLMDIGLPFYNG
CEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
YHWCTEIRRVSKVPVVFLSSAADNMNIVMAVSMGADDFIAKPFDLDVLTVKIQAIIRRCY
HHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHH
DFGANNSVLEHNGAMLNISDATITYDDKRLELTKNELKILQTLFDNKERIVSRSLLMEKL
HCCCCCCEEECCCCEEEECCCEEEECCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHH
WESDAYVDENTLSVNVNRLRKKLDSIGLESFIVTKKGLGYRLG
HCCCCCCCCCEEEEEHHHHHHHHHHCCCHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]