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The map label for this gene is bceS [H]

Identifier: 238925430

GI number: 238925430

Start: 2949851

End: 2950999

Strand: Reverse

Name: bceS [H]

Synonym: EUBREC_3085

Alternate gene names: 238925430

Gene position: 2950999-2949851 (Counterclockwise)

Preceding gene: 238925431

Following gene: 238925429

Centisome position: 85.54

GC content: 42.3

Gene sequence:

>1149_bases
ATGGCAAAAATACAAAACAAACCGCATCTGACAAATTTTATAAAACAAAACTATATATGGATTTTGATGATAGTCACAAT
GACCTGTATCCATTTGCTTTACATGTACCTGATTGGTGCGCGCAAACAGGATCTGGTGTATGCGGCAGTGCTTGATGCAA
TACTTCTTCTGATAACAGTTTTGGTTGGATTTTTCAGATATAGCAGCAAGGTAAAAGCTCTAAGCAATGCTTTAAAGCGT
CCGGTTGAGGAACAGGCACAGCTTCCGGAAGCAACAGATGATGTGGAGATGCTTTATCATCGGCTGCTGGAAAATCAAAG
TATTGCAAGAAGTGAGTCAGAAAGCAGTGCTGCAATCAGACAATCACAGATGAGAGATTATTACTCTATGTGGGTGCACC
AGATAAAGACCCCGATATCGGCTATGAAACTACTGCTTGAGGCAGAGCGGGAGGAGCTTGGGCAGCTTATATGTGATGAT
GAACAGAGTCAGTGCCATATAGGCGATATGACCGGTGGGAATATCGGTGCTGCAGGATTAAATGCTGCTTTGAAACAACA
GGCTGTACTCACAGAGCTGTCAGATAATGTGGCTTCATTTGAGGACGAATTGTTCCGCATAGAGGAATATGTCAGTATGG
CTTTGCAGTATCAGCGTGTGAGCAGCACCGAAAATGATTTTGTGCTTGAAAAAGTCAGTGTGGATGGTGTCATACGTGAT
ACCATTAAAAAATATGCAAAAATTATGATACGAAGGCATATTGGGATAAATTATTCAGGAACCGGGCAGGAGATATATAC
TGACGGAAAATGGCTTGCATTTATGCTGGAACAGATACTTTCAAATGCCATAAAATATACACCGCATGGGGTTGTTACAA
TAGAAACTGCAGAGGAAAAAGACCGGTTTTTTATTACAATAAAGGATACCGGAATAGGAATCAAAGCCGAGGATCTGCCA
CGTGTTTTTGAAAAGGGCTACACAGGCTACAATGGTCATGCCGATAAGAAGGCTACAGGAATTGGGCTTTATCTGTGCAG
GCAGATGGCAGATAAGCTGGGGCATACAATCCGCATGGAGTCAGAGATTGGAAAAGGAACTAAGGTGTGGATAGGGTTTG
ATCTGGATTATGCGGATGTGAGAGATTAG

Upstream 100 bases:

>100_bases
GGTGAATGTCAACAGGCTGCGTAAAAAGCTGGATTCTATAGGGCTTGAGAGCTTTATTGTCACAAAAAAGGGGCTTGGGT
ACAGGCTGGGGTGAGAGGTC

Downstream 100 bases:

>100_bases
GATAAATCGGTGTAATAAGTTTGACTGGAAATTGTATCCAAAATCAGATATAATATATATTATGAGAAATAAAAGAGTAT
GTGATTATATAGCGGAAGCT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAKIQNKPHLTNFIKQNYIWILMIVTMTCIHLLYMYLIGARKQDLVYAAVLDAILLLITVLVGFFRYSSKVKALSNALKR
PVEEQAQLPEATDDVEMLYHRLLENQSIARSESESSAAIRQSQMRDYYSMWVHQIKTPISAMKLLLEAEREELGQLICDD
EQSQCHIGDMTGGNIGAAGLNAALKQQAVLTELSDNVASFEDELFRIEEYVSMALQYQRVSSTENDFVLEKVSVDGVIRD
TIKKYAKIMIRRHIGINYSGTGQEIYTDGKWLAFMLEQILSNAIKYTPHGVVTIETAEEKDRFFITIKDTGIGIKAEDLP
RVFEKGYTGYNGHADKKATGIGLYLCRQMADKLGHTIRMESEIGKGTKVWIGFDLDYADVRD

Sequences:

>Translated_382_residues
MAKIQNKPHLTNFIKQNYIWILMIVTMTCIHLLYMYLIGARKQDLVYAAVLDAILLLITVLVGFFRYSSKVKALSNALKR
PVEEQAQLPEATDDVEMLYHRLLENQSIARSESESSAAIRQSQMRDYYSMWVHQIKTPISAMKLLLEAEREELGQLICDD
EQSQCHIGDMTGGNIGAAGLNAALKQQAVLTELSDNVASFEDELFRIEEYVSMALQYQRVSSTENDFVLEKVSVDGVIRD
TIKKYAKIMIRRHIGINYSGTGQEIYTDGKWLAFMLEQILSNAIKYTPHGVVTIETAEEKDRFFITIKDTGIGIKAEDLP
RVFEKGYTGYNGHADKKATGIGLYLCRQMADKLGHTIRMESEIGKGTKVWIGFDLDYADVRD
>Mature_381_residues
AKIQNKPHLTNFIKQNYIWILMIVTMTCIHLLYMYLIGARKQDLVYAAVLDAILLLITVLVGFFRYSSKVKALSNALKRP
VEEQAQLPEATDDVEMLYHRLLENQSIARSESESSAAIRQSQMRDYYSMWVHQIKTPISAMKLLLEAEREELGQLICDDE
QSQCHIGDMTGGNIGAAGLNAALKQQAVLTELSDNVASFEDELFRIEEYVSMALQYQRVSSTENDFVLEKVSVDGVIRDT
IKKYAKIMIRRHIGINYSGTGQEIYTDGKWLAFMLEQILSNAIKYTPHGVVTIETAEEKDRFFITIKDTGIGIKAEDLPR
VFEKGYTGYNGHADKKATGIGLYLCRQMADKLGHTIRMESEIGKGTKVWIGFDLDYADVRD

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=107, Percent_Identity=37.3831775700935, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI145693157, Length=170, Percent_Identity=24.1176470588235, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43306; Mature: 43175

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIQNKPHLTNFIKQNYIWILMIVTMTCIHLLYMYLIGARKQDLVYAAVLDAILLLITV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVGFFRYSSKVKALSNALKRPVEEQAQLPEATDDVEMLYHRLLENQSIARSESESSAAIR
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHH
QSQMRDYYSMWVHQIKTPISAMKLLLEAEREELGQLICDDEQSQCHIGDMTGGNIGAAGL
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHH
NAALKQQAVLTELSDNVASFEDELFRIEEYVSMALQYQRVSSTENDFVLEKVSVDGVIRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
TIKKYAKIMIRRHIGINYSGTGQEIYTDGKWLAFMLEQILSNAIKYTPHGVVTIETAEEK
HHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
DRFFITIKDTGIGIKAEDLPRVFEKGYTGYNGHADKKATGIGLYLCRQMADKLGHTIRME
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEH
SEIGKGTKVWIGFDLDYADVRD
HHCCCCCEEEEEECCCHHCCCC
>Mature Secondary Structure 
AKIQNKPHLTNFIKQNYIWILMIVTMTCIHLLYMYLIGARKQDLVYAAVLDAILLLITV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVGFFRYSSKVKALSNALKRPVEEQAQLPEATDDVEMLYHRLLENQSIARSESESSAAIR
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHH
QSQMRDYYSMWVHQIKTPISAMKLLLEAEREELGQLICDDEQSQCHIGDMTGGNIGAAGL
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHH
NAALKQQAVLTELSDNVASFEDELFRIEEYVSMALQYQRVSSTENDFVLEKVSVDGVIRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
TIKKYAKIMIRRHIGINYSGTGQEIYTDGKWLAFMLEQILSNAIKYTPHGVVTIETAEEK
HHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
DRFFITIKDTGIGIKAEDLPRVFEKGYTGYNGHADKKATGIGLYLCRQMADKLGHTIRME
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEH
SEIGKGTKVWIGFDLDYADVRD
HHCCCCCEEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132; 10086842 [H]