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The map label for this gene is hemN [C]

Identifier: 238925354

GI number: 238925354

Start: 2887070

End: 2888965

Strand: Reverse

Name: hemN [C]

Synonym: EUBREC_3009

Alternate gene names: 238925354

Gene position: 2888965-2887070 (Counterclockwise)

Preceding gene: 238925355

Following gene: 238925353

Centisome position: 83.75

GC content: 44.46

Gene sequence:

>1896_bases
ATGAACATTTTACTGACAGCAATAAATGCAAAATACATACATTCAAACCTTGCAGTTTACTCACTGCGCGCCTGTGCCGG
GGAGTACAGGGATGCTGTGGAGCTTGCGGAATACACGATAAACAATCAGAAGGATTACATTCTTGAGGAGCTTTATAAGA
GGAAGCCCGACGTACTTTGTTTTTCGTGCTATATATGGAATATTGATTATGTGACTGATATTGCACGCGAGTATAAAAAG
CTTTGTCCGTCAGTGCCGATATGGGTTGGAGGCCCTGAGGTGTCTTACGAGGTGGAGGCATTTCTGCGGGAAAATCCATA
CATAGACGGTGTGATGATAGGCGAGGGTGAGGATACCTTTAGAGAGCTGTGTGGTTACTATGCGCATAAAAGAAAGCTGA
GTGATATTGCAGGCATTGCTTTCAGAAAAAACAGCACAGGTAATAGTACAAGTAATAGAACAAGTGTGAACAACGCAGGC
TGCAAAGCGGATGAAATAGTATTTACAAGTCCACGCCCAATCAAAAACATGAGTGAAATCCCATTCTGCTATGATACGCT
TGATGATTTTTCAAACCGCATCATCTACTACGAGAGCAGCAGGGGATGCCCGTTTTCGTGCAGCTATTGCCTGTCATCGG
TGGATAAGACACTGCGTTTCAGGGATACTGAGATTGTCAAAAGGGAGCTTAAGTTTTTCATAGACCAGAAGGTGCCTCAG
ATTAAGTTTGTGGACAGAACCTTCAACTGCAATCATGCTCATGCCATGGAGCTGTGGCGCTTTATAAAGGCGAATGACAA
TGGTGTGACAAACTTTCACTTTGAGATATCGGCGGATCTGCTGAATCAGGAGGAGATTGAGCTGATTTCTGATATGAGGC
CGGGGCTGATACAGCTTGAAATCGGTGTGCAGTCCACTAATGAGGTCACGATTAAGGAGATTCACAGGACTATGAAGCTT
GAGAGGCTTAAGGAGGTTGTGAGGCTCATTCAAAGCGGCAACAATATCCACGAGCATCTGGATCTGATTGCAGGGCTGCC
ATACGAGGACTATGATAGCTTTGGGCGTTCTTTTGATGAGATTTATGAGCTTAAGCCAAACCAGCTGCAGCTGGGATTTT
TAAAGGTGCTCAAGGGCTCGTATATGTTTGAGCATGCCGCGGAATATGGTATTGTCTACCATGACAAGCCACCGTATGAG
GTTATGTCCACAAAATGGCTTTCGTTTGATGATGTGATAAAGATTAAGCGCGTCGAGGATATGCTTGAGGTGTATTACAA
CAGCGGACAGTTTGAGATTACGATGAAGCTCATGGAGTGTATCTTTGACAGTGCGTTTGAGTTTTTTCAGGAGCTTGGAG
ATTTTTATGAGGCAAACGGCTATTTTGGAATGAGCCATTCGCGCATCAGAAGGTGTGAGATACTGCTTGAGTTTCTGGCT
TTATACCTGCATGGCTGTGACCGCGATGCTATAACTTCTGTGGTATTATCAGAAAATGCCGGAGATAGAGATAATACTGA
TTTTGACGAAAATGCCATAGATAGAGATAGTACTGATTTTGATGAAAATGCGCAGATTTACAACATGATTCAGGAGTCAC
TCATCTTTGATTTGTACTATCGTGAAAACTGCAAGAGCCGCCCGAGGTGGGCCACAGATATAGGCAAATTCAAGCATATG
ACACATGCATACTGTAAGAATGGAAAGCTATCGCATGTGGAGCCGTTCCACTATATTTTTCCTGACAAGCACATGCGCAA
GCTGGATGAACTGCCAAAGTATCATAAGGAGCCGGTGTGGGCGCTTTTCCACTACGACATGAGAGACCCGCTTGACCACC
AGGCGCTGGTGGAGTATGTAGATAACAGTAAAAAGCCGGGAAGGTTTACGGACTAA

Upstream 100 bases:

>100_bases
GTTAAAAAAATAAAATTGAACGGATGCTGCAATAATACGAAGCAGACCTTTGAATGTGGTATAAAGTCTACATTCAAGGG
TCATTTTTTAAGGAGAAACC

Downstream 100 bases:

>100_bases
GAAAAATGAGCAACATAGACAATATAAAAAATTACACGGTGATTGACCTTGAAATGACAGGTCTTTCAGCTAAAAACGAC
AAGATAATAGAGATAGGTGC

Product: magnesium-protoporphyrin IX monomethyl ester oxidative cyclase

Products: Protoporphyrinogen-IX; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MNILLTAINAKYIHSNLAVYSLRACAGEYRDAVELAEYTINNQKDYILEELYKRKPDVLCFSCYIWNIDYVTDIAREYKK
LCPSVPIWVGGPEVSYEVEAFLRENPYIDGVMIGEGEDTFRELCGYYAHKRKLSDIAGIAFRKNSTGNSTSNRTSVNNAG
CKADEIVFTSPRPIKNMSEIPFCYDTLDDFSNRIIYYESSRGCPFSCSYCLSSVDKTLRFRDTEIVKRELKFFIDQKVPQ
IKFVDRTFNCNHAHAMELWRFIKANDNGVTNFHFEISADLLNQEEIELISDMRPGLIQLEIGVQSTNEVTIKEIHRTMKL
ERLKEVVRLIQSGNNIHEHLDLIAGLPYEDYDSFGRSFDEIYELKPNQLQLGFLKVLKGSYMFEHAAEYGIVYHDKPPYE
VMSTKWLSFDDVIKIKRVEDMLEVYYNSGQFEITMKLMECIFDSAFEFFQELGDFYEANGYFGMSHSRIRRCEILLEFLA
LYLHGCDRDAITSVVLSENAGDRDNTDFDENAIDRDSTDFDENAQIYNMIQESLIFDLYYRENCKSRPRWATDIGKFKHM
THAYCKNGKLSHVEPFHYIFPDKHMRKLDELPKYHKEPVWALFHYDMRDPLDHQALVEYVDNSKKPGRFTD

Sequences:

>Translated_631_residues
MNILLTAINAKYIHSNLAVYSLRACAGEYRDAVELAEYTINNQKDYILEELYKRKPDVLCFSCYIWNIDYVTDIAREYKK
LCPSVPIWVGGPEVSYEVEAFLRENPYIDGVMIGEGEDTFRELCGYYAHKRKLSDIAGIAFRKNSTGNSTSNRTSVNNAG
CKADEIVFTSPRPIKNMSEIPFCYDTLDDFSNRIIYYESSRGCPFSCSYCLSSVDKTLRFRDTEIVKRELKFFIDQKVPQ
IKFVDRTFNCNHAHAMELWRFIKANDNGVTNFHFEISADLLNQEEIELISDMRPGLIQLEIGVQSTNEVTIKEIHRTMKL
ERLKEVVRLIQSGNNIHEHLDLIAGLPYEDYDSFGRSFDEIYELKPNQLQLGFLKVLKGSYMFEHAAEYGIVYHDKPPYE
VMSTKWLSFDDVIKIKRVEDMLEVYYNSGQFEITMKLMECIFDSAFEFFQELGDFYEANGYFGMSHSRIRRCEILLEFLA
LYLHGCDRDAITSVVLSENAGDRDNTDFDENAIDRDSTDFDENAQIYNMIQESLIFDLYYRENCKSRPRWATDIGKFKHM
THAYCKNGKLSHVEPFHYIFPDKHMRKLDELPKYHKEPVWALFHYDMRDPLDHQALVEYVDNSKKPGRFTD
>Mature_631_residues
MNILLTAINAKYIHSNLAVYSLRACAGEYRDAVELAEYTINNQKDYILEELYKRKPDVLCFSCYIWNIDYVTDIAREYKK
LCPSVPIWVGGPEVSYEVEAFLRENPYIDGVMIGEGEDTFRELCGYYAHKRKLSDIAGIAFRKNSTGNSTSNRTSVNNAG
CKADEIVFTSPRPIKNMSEIPFCYDTLDDFSNRIIYYESSRGCPFSCSYCLSSVDKTLRFRDTEIVKRELKFFIDQKVPQ
IKFVDRTFNCNHAHAMELWRFIKANDNGVTNFHFEISADLLNQEEIELISDMRPGLIQLEIGVQSTNEVTIKEIHRTMKL
ERLKEVVRLIQSGNNIHEHLDLIAGLPYEDYDSFGRSFDEIYELKPNQLQLGFLKVLKGSYMFEHAAEYGIVYHDKPPYE
VMSTKWLSFDDVIKIKRVEDMLEVYYNSGQFEITMKLMECIFDSAFEFFQELGDFYEANGYFGMSHSRIRRCEILLEFLA
LYLHGCDRDAITSVVLSENAGDRDNTDFDENAIDRDSTDFDENAQIYNMIQESLIFDLYYRENCKSRPRWATDIGKFKHM
THAYCKNGKLSHVEPFHYIFPDKHMRKLDELPKYHKEPVWALFHYDMRDPLDHQALVEYVDNSKKPGRFTD

Specific function: Anaerobic Transformation Of Coproporphyrinogen-III Into Protoporphyrinogen-IX. [C]

COG id: COG1032

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR007197 [H]

Pfam domain/function: PF02310 B12-binding; PF04055 Radical_SAM [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 73767; Mature: 73767

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLTAINAKYIHSNLAVYSLRACAGEYRDAVELAEYTINNQKDYILEELYKRKPDVLC
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
FSCYIWNIDYVTDIAREYKKLCPSVPIWVGGPEVSYEVEAFLRENPYIDGVMIGEGEDTF
EEEEEECHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCEEEECCCHHHH
RELCGYYAHKRKLSDIAGIAFRKNSTGNSTSNRTSVNNAGCKADEIVFTSPRPIKNMSEI
HHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
PFCYDTLDDFSNRIIYYESSRGCPFSCSYCLSSVDKTLRFRDTEIVKRELKFFIDQKVPQ
CHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
IKFVDRTFNCNHAHAMELWRFIKANDNGVTNFHFEISADLLNQEEIELISDMRPGLIQLE
EEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEHHHCCHHHHHHHHHCCCCEEEEE
IGVQSTNEVTIKEIHRTMKLERLKEVVRLIQSGNNIHEHLDLIAGLPYEDYDSFGRSFDE
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCHHH
IYELKPNQLQLGFLKVLKGSYMFEHAAEYGIVYHDKPPYEVMSTKWLSFDDVIKIKRVED
HHHCCCCCCHHHHHHHHHCCHHHHHHHHCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHH
MLEVYYNSGQFEITMKLMECIFDSAFEFFQELGDFYEANGYFGMSHSRIRRCEILLEFLA
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHH
LYLHGCDRDAITSVVLSENAGDRDNTDFDENAIDRDSTDFDENAQIYNMIQESLIFDLYY
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RENCKSRPRWATDIGKFKHMTHAYCKNGKLSHVEPFHYIFPDKHMRKLDELPKYHKEPVW
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCEE
ALFHYDMRDPLDHQALVEYVDNSKKPGRFTD
EEEECCCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNILLTAINAKYIHSNLAVYSLRACAGEYRDAVELAEYTINNQKDYILEELYKRKPDVLC
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
FSCYIWNIDYVTDIAREYKKLCPSVPIWVGGPEVSYEVEAFLRENPYIDGVMIGEGEDTF
EEEEEECHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCEEEECCCHHHH
RELCGYYAHKRKLSDIAGIAFRKNSTGNSTSNRTSVNNAGCKADEIVFTSPRPIKNMSEI
HHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
PFCYDTLDDFSNRIIYYESSRGCPFSCSYCLSSVDKTLRFRDTEIVKRELKFFIDQKVPQ
CHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
IKFVDRTFNCNHAHAMELWRFIKANDNGVTNFHFEISADLLNQEEIELISDMRPGLIQLE
EEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEHHHCCHHHHHHHHHCCCCEEEEE
IGVQSTNEVTIKEIHRTMKLERLKEVVRLIQSGNNIHEHLDLIAGLPYEDYDSFGRSFDE
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCHHH
IYELKPNQLQLGFLKVLKGSYMFEHAAEYGIVYHDKPPYEVMSTKWLSFDDVIKIKRVED
HHHCCCCCCHHHHHHHHHCCHHHHHHHHCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHH
MLEVYYNSGQFEITMKLMECIFDSAFEFFQELGDFYEANGYFGMSHSRIRRCEILLEFLA
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHH
LYLHGCDRDAITSVVLSENAGDRDNTDFDENAIDRDSTDFDENAQIYNMIQESLIFDLYY
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RENCKSRPRWATDIGKFKHMTHAYCKNGKLSHVEPFHYIFPDKHMRKLDELPKYHKEPVW
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCEE
ALFHYDMRDPLDHQALVEYVDNSKKPGRFTD
EEEECCCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen-III; O2 [C]

Specific reaction: coproporphyrinogen-III + O2 = protoporphyrinogen-IX + 2 CO2 [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]