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The map label for this gene is guaA [H]

Identifier: 238925280

GI number: 238925280

Start: 2817786

End: 2818736

Strand: Reverse

Name: guaA [H]

Synonym: EUBREC_2934

Alternate gene names: 238925280

Gene position: 2818736-2817786 (Counterclockwise)

Preceding gene: 238925281

Following gene: 238925279

Centisome position: 81.71

GC content: 45.95

Gene sequence:

>951_bases
ATGATAATAATTATTGATGAGGCAAGCGCAAAACTTGCCTCTTTTTACTATCATGACGAGATATTCAAGCCACAGTGGAA
GTGCGCAGCCGATATGTCATCTGCGTCAGACGAGTTGCATGATGAATTTCAGGAAAAACTGCAAGAAAAACTGCCTGATG
AGCTGCGGGAAAAACTGTATGTTGTGCTACCGGCAGATGAATCAATTAATGACTTCCAAAAAACAACGATACAAGAATCT
GCAGATAACACAGCGAAAGCTAATACGGGAAATCTAAGAATACCGAAAGCTCCCACCGACTGCATCTGGATAGTATCCGA
CAGGCAGCAGAAGCAAATAGCTGACTCACTCGGCATAGCATCGGTAGGAGAACCGCAGTGTGGCACGCGCTATGCAGTGG
AAAGCCTTGCAGAGCTTGATATTGAGTATCTTGAGCGGGTGCGCAGGCGGTATAATCATATCCCATGGGATATTGGCGAG
ACAGACAGATGCCTGATACGTGAGCTTTCACTGGCAGACCTTCCGGCGCTCTATGAGCTTTATGACAAGCCCGGCATGAC
AGACTTTGTGGAACCGCTTTACGACTACGAGACAGAGCTTGAATACCAGAAAGCATACATAGAGAACATGTATGACTTTT
ACGAGTATGGTATGTGGCTTGTGTTTTCAAAGGAAACAGGGAAGCTGATAGGACGGGCGGGACTTGAGCACAATGAAATG
GGTTATATGATAGCACCGGAATTTCAGAACCTGGGCTATGCCACGGAGGTGTGCCGCTTTATCGTAGACTATGCGCGGAA
AAACACAGACTTTGAGGAGCTCTACTGCCGGATAGATGAGAAAAATGTGGCATCGGTGCGTCTTGCAAAAAGACTTGGAT
TTGTCAGAAACGGACAAATCGGGAATGAGAGAAATACCGGTGGATTAGATAGGTATGTTCTTTCAATCTGA

Upstream 100 bases:

>100_bases
TGCGCACAGACTACATGGACAAACCACTTGAGGCTCAGGTCATGAAGACAGTTACAGTTGAGACCTTCGGAGTGGACTAT
CCGGAGCCGGAGACAGTTTA

Downstream 100 bases:

>100_bases
CAGTTCATTATATATTTTATATGTTCAGCAGGAACAGCTCGGCAGGATTCATTCAGATATAAGAACTGAATAATTGCCTG
ATAGAAAGGAATGTGCATAA

Product: guanosine monophosphate synthetase GuaA

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIIIIDEASAKLASFYYHDEIFKPQWKCAADMSSASDELHDEFQEKLQEKLPDELREKLYVVLPADESINDFQKTTIQES
ADNTAKANTGNLRIPKAPTDCIWIVSDRQQKQIADSLGIASVGEPQCGTRYAVESLAELDIEYLERVRRRYNHIPWDIGE
TDRCLIRELSLADLPALYELYDKPGMTDFVEPLYDYETELEYQKAYIENMYDFYEYGMWLVFSKETGKLIGRAGLEHNEM
GYMIAPEFQNLGYATEVCRFIVDYARKNTDFEELYCRIDEKNVASVRLAKRLGFVRNGQIGNERNTGGLDRYVLSI

Sequences:

>Translated_316_residues
MIIIIDEASAKLASFYYHDEIFKPQWKCAADMSSASDELHDEFQEKLQEKLPDELREKLYVVLPADESINDFQKTTIQES
ADNTAKANTGNLRIPKAPTDCIWIVSDRQQKQIADSLGIASVGEPQCGTRYAVESLAELDIEYLERVRRRYNHIPWDIGE
TDRCLIRELSLADLPALYELYDKPGMTDFVEPLYDYETELEYQKAYIENMYDFYEYGMWLVFSKETGKLIGRAGLEHNEM
GYMIAPEFQNLGYATEVCRFIVDYARKNTDFEELYCRIDEKNVASVRLAKRLGFVRNGQIGNERNTGGLDRYVLSI
>Mature_316_residues
MIIIIDEASAKLASFYYHDEIFKPQWKCAADMSSASDELHDEFQEKLQEKLPDELREKLYVVLPADESINDFQKTTIQES
ADNTAKANTGNLRIPKAPTDCIWIVSDRQQKQIADSLGIASVGEPQCGTRYAVESLAELDIEYLERVRRRYNHIPWDIGE
TDRCLIRELSLADLPALYELYDKPGMTDFVEPLYDYETELEYQKAYIENMYDFYEYGMWLVFSKETGKLIGRAGLEHNEM
GYMIAPEFQNLGYATEVCRFIVDYARKNTDFEELYCRIDEKNVASVRLAKRLGFVRNGQIGNERNTGGLDRYVLSI

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 36559; Mature: 36559

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIIDEASAKLASFYYHDEIFKPQWKCAADMSSASDELHDEFQEKLQEKLPDELREKLY
CEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCEE
VVLPADESINDFQKTTIQESADNTAKANTGNLRIPKAPTDCIWIVSDRQQKQIADSLGIA
EEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHCCCC
SVGEPQCGTRYAVESLAELDIEYLERVRRRYNHIPWDIGETDRCLIRELSLADLPALYEL
CCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YDKPGMTDFVEPLYDYETELEYQKAYIENMYDFYEYGMWLVFSKETGKLIGRAGLEHNEM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHCCCCCCCC
GYMIAPEFQNLGYATEVCRFIVDYARKNTDFEELYCRIDEKNVASVRLAKRLGFVRNGQI
CEEECCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
GNERNTGGLDRYVLSI
CCCCCCCCHHHHEECC
>Mature Secondary Structure
MIIIIDEASAKLASFYYHDEIFKPQWKCAADMSSASDELHDEFQEKLQEKLPDELREKLY
CEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCEE
VVLPADESINDFQKTTIQESADNTAKANTGNLRIPKAPTDCIWIVSDRQQKQIADSLGIA
EEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHCCCC
SVGEPQCGTRYAVESLAELDIEYLERVRRRYNHIPWDIGETDRCLIRELSLADLPALYEL
CCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YDKPGMTDFVEPLYDYETELEYQKAYIENMYDFYEYGMWLVFSKETGKLIGRAGLEHNEM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHCCCCCCCC
GYMIAPEFQNLGYATEVCRFIVDYARKNTDFEELYCRIDEKNVASVRLAKRLGFVRNGQI
CEEECCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
GNERNTGGLDRYVLSI
CCCCCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]