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The map label for this gene is glcK [H]

Identifier: 238925278

GI number: 238925278

Start: 2815345

End: 2816289

Strand: Reverse

Name: glcK [H]

Synonym: EUBREC_2932

Alternate gene names: 238925278

Gene position: 2816289-2815345 (Counterclockwise)

Preceding gene: 238925279

Following gene: 238925277

Centisome position: 81.64

GC content: 51.75

Gene sequence:

>945_bases
ATGAAGAAATATGCATACGGAGTAGATATAGGTGGAACAACTGTAAAGATAGGCTTTTTCGAGACCACAGGAAAGCTTGT
CGATACATGGGAGATTCCTACACGCACAGAGAATTCAGGCGAGCTCATCCTGCCTGATATCGCAGCATCCATCAAGGAGA
ATAACGAGAAGCATGGCATAGAGATGGGTGACATCGAGGGCGTAGGCATGGGAGTGCCGGGACCTATAAAGGATGACGGA
ACAGTATTGAAGTGTGTCAACCTCGGCTGGGGCGTGTTCAACGTGGCACAGTCACTCTCAGTACTGTGCGGCGGCATCAA
GGTAAAGGCCGGAAACGATGCCAACGTAGCTGCACTCGGTGAGATGTGGCAGGGTGGCGGAAAGGGTCATCAGGATGTAG
TCATGATCACACTCGGCACAGGCGTAGGCGGAGGAATCATCCGCGAGGGCAGAATCGTAGCCGGAGTAAACGGAGCAGGC
GGAGAGATAGGACATATGCCTATGGTAGATGATGAGTCAGAGTGCTGTGGCTGCGGCAAGAAGGGCTGCTTAGAGCAGTA
TGCATCAGCAAACGGTCTTGTAAGAGTGGCAGAGAGATACATTGCAGCACACAGGGATGTGGCAACAAAGCTTGATTTAA
ATGCAGGCTTCACAGCCAAGGATGTATGCGATGCGGCAAAGGCAGGAGATGCAGCGGGCATTGCAGCAGTAGAGCAGTCT
ATGAAGCTTCTCGGCAAGGCAATGGCAGCAGTAGCATGCGTCATGGACCCTGAGGTATTTGTTGTAGGCGGAGGCCTCTC
AAAGGCAGGAAGCATCATCATCGATACAGCAGCAAAGTACTATAAAGAGTATGCTTTCCATGCAAGCCGTGAGACAGAGA
TCAAGCTCGCCACACTCGGCAACTCAGCCGGCATGTATGGCGGAGTAAAGATGGTTATCGGCTAA

Upstream 100 bases:

>100_bases
GGCAAAATTACGGATTTTAAAAAAATAGTAAAAAACATTGAAAAATATACAATTAGGCAATAAAATATAAACATAGTTTA
ACGATTTGGAGGACGAAAAA

Downstream 100 bases:

>100_bases
CAACATAAGATTGCAATTTTTAAAGAAATAAAATATAATGGCTACTAAAGATACACTACAATCGAGGTGAGACTATTGGC
AGATTACTCAACAGAAGAAT

Product: transcriptional regulator/sugar kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKKYAYGVDIGGTTVKIGFFETTGKLVDTWEIPTRTENSGELILPDIAASIKENNEKHGIEMGDIEGVGMGVPGPIKDDG
TVLKCVNLGWGVFNVAQSLSVLCGGIKVKAGNDANVAALGEMWQGGGKGHQDVVMITLGTGVGGGIIREGRIVAGVNGAG
GEIGHMPMVDDESECCGCGKKGCLEQYASANGLVRVAERYIAAHRDVATKLDLNAGFTAKDVCDAAKAGDAAGIAAVEQS
MKLLGKAMAAVACVMDPEVFVVGGGLSKAGSIIIDTAAKYYKEYAFHASRETEIKLATLGNSAGMYGGVKMVIG

Sequences:

>Translated_314_residues
MKKYAYGVDIGGTTVKIGFFETTGKLVDTWEIPTRTENSGELILPDIAASIKENNEKHGIEMGDIEGVGMGVPGPIKDDG
TVLKCVNLGWGVFNVAQSLSVLCGGIKVKAGNDANVAALGEMWQGGGKGHQDVVMITLGTGVGGGIIREGRIVAGVNGAG
GEIGHMPMVDDESECCGCGKKGCLEQYASANGLVRVAERYIAAHRDVATKLDLNAGFTAKDVCDAAKAGDAAGIAAVEQS
MKLLGKAMAAVACVMDPEVFVVGGGLSKAGSIIIDTAAKYYKEYAFHASRETEIKLATLGNSAGMYGGVKMVIG
>Mature_314_residues
MKKYAYGVDIGGTTVKIGFFETTGKLVDTWEIPTRTENSGELILPDIAASIKENNEKHGIEMGDIEGVGMGVPGPIKDDG
TVLKCVNLGWGVFNVAQSLSVLCGGIKVKAGNDANVAALGEMWQGGGKGHQDVVMITLGTGVGGGIIREGRIVAGVNGAG
GEIGHMPMVDDESECCGCGKKGCLEQYASANGLVRVAERYIAAHRDVATKLDLNAGFTAKDVCDAAKAGDAAGIAAVEQS
MKLLGKAMAAVACVMDPEVFVVGGGLSKAGSIIIDTAAKYYKEYAFHASRETEIKLATLGNSAGMYGGVKMVIG

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=274, Percent_Identity=28.4671532846715, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI298566325, Length=274, Percent_Identity=28.4671532846715, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4885285, Length=271, Percent_Identity=28.0442804428044, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI190014632, Length=271, Percent_Identity=28.0442804428044, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787363, Length=314, Percent_Identity=29.2993630573248, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081733, Length=311, Percent_Identity=28.6173633440514, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786891, Length=293, Percent_Identity=26.2798634812287, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787878, Length=282, Percent_Identity=23.0496453900709, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082230, Length=284, Percent_Identity=28.8732394366197, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082127, Length=152, Percent_Identity=28.2894736842105, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790522, Length=287, Percent_Identity=24.7386759581882, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 32353; Mature: 32353

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYAYGVDIGGTTVKIGFFETTGKLVDTWEIPTRTENSGELILPDIAASIKENNEKHGI
CCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCCCC
EMGDIEGVGMGVPGPIKDDGTVLKCVNLGWGVFNVAQSLSVLCGGIKVKAGNDANVAALG
EECCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCHHHHH
EMWQGGGKGHQDVVMITLGTGVGGGIIREGRIVAGVNGAGGEIGHMPMVDDESECCGCGK
HHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCHHHHCCCC
KGCLEQYASANGLVRVAERYIAAHRDVATKLDLNAGFTAKDVCDAAKAGDAAGIAAVEQS
HHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHH
MKLLGKAMAAVACVMDPEVFVVGGGLSKAGSIIIDTAAKYYKEYAFHASRETEIKLATLG
HHHHHHHHHHHHHEECCCEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEEEEEEC
NSAGMYGGVKMVIG
CCCCCCCCEEEEEC
>Mature Secondary Structure
MKKYAYGVDIGGTTVKIGFFETTGKLVDTWEIPTRTENSGELILPDIAASIKENNEKHGI
CCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCCCC
EMGDIEGVGMGVPGPIKDDGTVLKCVNLGWGVFNVAQSLSVLCGGIKVKAGNDANVAALG
EECCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCHHHHH
EMWQGGGKGHQDVVMITLGTGVGGGIIREGRIVAGVNGAGGEIGHMPMVDDESECCGCGK
HHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCHHHHCCCC
KGCLEQYASANGLVRVAERYIAAHRDVATKLDLNAGFTAKDVCDAAKAGDAAGIAAVEQS
HHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHH
MKLLGKAMAAVACVMDPEVFVVGGGLSKAGSIIIDTAAKYYKEYAFHASRETEIKLATLG
HHHHHHHHHHHHHEECCCEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEEEEEEC
NSAGMYGGVKMVIG
CCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]