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The map label for this gene is ygcA [C]

Identifier: 238925258

GI number: 238925258

Start: 2789680

End: 2791161

Strand: Reverse

Name: ygcA [C]

Synonym: EUBREC_2912

Alternate gene names: 238925258

Gene position: 2791161-2789680 (Counterclockwise)

Preceding gene: 238925259

Following gene: 238925257

Centisome position: 80.91

GC content: 45.68

Gene sequence:

>1482_bases
ATGAAAAAAAATGACATATTTGAACTTGAAATAACAGATATGGGAACAGATGGCGAGGGTATCGGACATTATGATGGCAT
GACCTTTTTCGTAAAGGATGCACTGATTGGTGACGTCATAACAGCCCGCGCAACAAAATTAAAGAAAAACTATGGCTACG
CAAGAGTGGAAGAGATTAAGACCCCTTCCACTTTTCGCGTTGAGCCGCAATGTGAGCTGCACAAGAGGTGTGGCGGCTGC
CAGATACAGGCGCTCTCTTATGAAAAGCAGCTTGAATTTAAAAATAATAAGGTGCGCAACAATCTCATGCGTATAGGTGG
ATTTTCCGAGGCAAAGCTGGACAGTAAAATGCAGCCGCCTGTTGGCACAGACAATCCATATCGCTACCGCAACAAGGCAC
AGTTTCCGGTGGGATATGACAGGGATGGCAATATAGTGACAGGCTTTTATGCATCGCGAAGCCACAATATCATCCCAGTT
GAGGACTGCAGGCTTGGGGTGCCGCAAAACAAAGAGATACTGGATATCATAAAGGAATGGATGAATGAGTGTGGCATCAC
GCCGTATGACGAGAACACACACAAAGGGCTCGTGCGCCATGTGCTTATCAGATATGGATTTACATCAAAGCAGATTATGG
TGTGTCTTGTGATAAATGGGGACAGTCTTGAAGCAAAACGCCGAGCCGGGAATGCAGCAGATATACTGTGCGAAAGACTC
TCAAAAATCGATGGAATGACTTCGATTTCTTACAATATCAACAAGGAAAACACAAATGTCATCCTCGGCAAAAAGACAGT
CTGCATATGGGGCAGACCATATATTGAGGACACCATCCATCTGCTTTCTTACCCTGATTTCACACCACAGGGGACAGGCA
TCACATATCAGATTTCGCCACAGTCGTTCTATCAGGTAAACCCGAAGCAGACAGAAAAGCTTTACAGCACGGCACTTGCA
TTTGCAGGGCTCACAGGAAATGAAAATGTCTGGGATCTCTACTGTGGTATCGGTACCATATCGCTCTTTTTGTCACAGAA
GGCAAAGCAGGTGTACGGAGTGGAAATAGTGCCTCAGGCAATCGAGGATGCCAAAAACAATGCGAAGCTCAATGGCATCA
CAAATGCACAGTTTTTCGTAGGAAAGGCTGAGGATGTGCTGCCACAGTTTTATGAGAATGCAAAGAAAAAAGAGAATATC
ACTGATGATACAGCATCCACCGGACATACAGATATGCTTCGCCCGGATGTGATAGTCGTTGACCCGCCAAGAAAGGGCTG
TGATGAGAAGTGCCTGGACACAATGCTTGCGATGTCACCGGAGAGGATTGTATATGTGAGCTGCGATTCGGCAACATTGG
CAAGGGATTTGAAGATACTCTGTGAAGAGAAGTATGAACTCATGAAGTGGCAGGCATTTGATCAGTTTTCTCATACGACG
CATGTAGAAAGTATTTGCCTCCTCGAGCGGGTGAGCAACTGA

Upstream 100 bases:

>100_bases
TATTAAATATAGCTATGGTGTGATTTTTGGTGTGAAAGCTTGCGCCGGATACAAACATTATAAAGAGTAATTATATATAT
AAAATAAAGAAGAGAAAAGC

Downstream 100 bases:

>100_bases
AAAATATTGATATGAACTAAGTAAATTTATAGACATTTTCTTATCGTAAAGCTATAATATTAAAATCATATAGAACAGAT
AGACATTGATTTTAGAAAGT

Product: hypothetical RNA methyltransferase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MKKNDIFELEITDMGTDGEGIGHYDGMTFFVKDALIGDVITARATKLKKNYGYARVEEIKTPSTFRVEPQCELHKRCGGC
QIQALSYEKQLEFKNNKVRNNLMRIGGFSEAKLDSKMQPPVGTDNPYRYRNKAQFPVGYDRDGNIVTGFYASRSHNIIPV
EDCRLGVPQNKEILDIIKEWMNECGITPYDENTHKGLVRHVLIRYGFTSKQIMVCLVINGDSLEAKRRAGNAADILCERL
SKIDGMTSISYNINKENTNVILGKKTVCIWGRPYIEDTIHLLSYPDFTPQGTGITYQISPQSFYQVNPKQTEKLYSTALA
FAGLTGNENVWDLYCGIGTISLFLSQKAKQVYGVEIVPQAIEDAKNNAKLNGITNAQFFVGKAEDVLPQFYENAKKKENI
TDDTASTGHTDMLRPDVIVVDPPRKGCDEKCLDTMLAMSPERIVYVSCDSATLARDLKILCEEKYELMKWQAFDQFSHTT
HVESICLLERVSN

Sequences:

>Translated_493_residues
MKKNDIFELEITDMGTDGEGIGHYDGMTFFVKDALIGDVITARATKLKKNYGYARVEEIKTPSTFRVEPQCELHKRCGGC
QIQALSYEKQLEFKNNKVRNNLMRIGGFSEAKLDSKMQPPVGTDNPYRYRNKAQFPVGYDRDGNIVTGFYASRSHNIIPV
EDCRLGVPQNKEILDIIKEWMNECGITPYDENTHKGLVRHVLIRYGFTSKQIMVCLVINGDSLEAKRRAGNAADILCERL
SKIDGMTSISYNINKENTNVILGKKTVCIWGRPYIEDTIHLLSYPDFTPQGTGITYQISPQSFYQVNPKQTEKLYSTALA
FAGLTGNENVWDLYCGIGTISLFLSQKAKQVYGVEIVPQAIEDAKNNAKLNGITNAQFFVGKAEDVLPQFYENAKKKENI
TDDTASTGHTDMLRPDVIVVDPPRKGCDEKCLDTMLAMSPERIVYVSCDSATLARDLKILCEEKYELMKWQAFDQFSHTT
HVESICLLERVSN
>Mature_493_residues
MKKNDIFELEITDMGTDGEGIGHYDGMTFFVKDALIGDVITARATKLKKNYGYARVEEIKTPSTFRVEPQCELHKRCGGC
QIQALSYEKQLEFKNNKVRNNLMRIGGFSEAKLDSKMQPPVGTDNPYRYRNKAQFPVGYDRDGNIVTGFYASRSHNIIPV
EDCRLGVPQNKEILDIIKEWMNECGITPYDENTHKGLVRHVLIRYGFTSKQIMVCLVINGDSLEAKRRAGNAADILCERL
SKIDGMTSISYNINKENTNVILGKKTVCIWGRPYIEDTIHLLSYPDFTPQGTGITYQISPQSFYQVNPKQTEKLYSTALA
FAGLTGNENVWDLYCGIGTISLFLSQKAKQVYGVEIVPQAIEDAKNNAKLNGITNAQFFVGKAEDVLPQFYENAKKKENI
TDDTASTGHTDMLRPDVIVVDPPRKGCDEKCLDTMLAMSPERIVYVSCDSATLARDLKILCEEKYELMKWQAFDQFSHTT
HVESICLLERVSN

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=385, Percent_Identity=27.5324675324675, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI51173878, Length=385, Percent_Identity=27.5324675324675, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI269784680, Length=440, Percent_Identity=25, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI269784676, Length=440, Percent_Identity=25, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI20149688, Length=440, Percent_Identity=25, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI269784678, Length=382, Percent_Identity=25.9162303664921, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1789148, Length=488, Percent_Identity=27.0491803278689, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787083, Length=423, Percent_Identity=25.531914893617, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790403, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71997438, Length=177, Percent_Identity=29.9435028248588, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322909, Length=473, Percent_Identity=24.9471458773784, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666579, Length=490, Percent_Identity=25.3061224489796, Blast_Score=139, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 55630; Mature: 55630

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNDIFELEITDMGTDGEGIGHYDGMTFFVKDALIGDVITARATKLKKNYGYARVEEIK
CCCCCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEHHHCC
TPSTFRVEPQCELHKRCGGCQIQALSYEKQLEFKNNKVRNNLMRIGGFSEAKLDSKMQPP
CCCEEEECCCHHHHHCCCCCEEEEECCHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCCC
VGTDNPYRYRNKAQFPVGYDRDGNIVTGFYASRSHNIIPVEDCRLGVPQNKEILDIIKEW
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHHHCCCCCCCCHHHHHHHHHH
MNECGITPYDENTHKGLVRHVLIRYGFTSKQIMVCLVINGDSLEAKRRAGNAADILCERL
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHH
SKIDGMTSISYNINKENTNVILGKKTVCIWGRPYIEDTIHLLSYPDFTPQGTGITYQISP
HHHCCCEEEEEEECCCCCEEEEECEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECC
QSFYQVNPKQTEKLYSTALAFAGLTGNENVWDLYCGIGTISLFLSQKAKQVYGVEIVPQA
CCEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCEEEEHHH
IEDAKNNAKLNGITNAQFFVGKAEDVLPQFYENAKKKENITDDTASTGHTDMLRPDVIVV
HHCCCCCCEECCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
DPPRKGCDEKCLDTMLAMSPERIVYVSCDSATLARDLKILCEEKYELMKWQAFDQFSHTT
CCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HVESICLLERVSN
HHHHHHHHHHHCC
>Mature Secondary Structure
MKKNDIFELEITDMGTDGEGIGHYDGMTFFVKDALIGDVITARATKLKKNYGYARVEEIK
CCCCCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEHHHCC
TPSTFRVEPQCELHKRCGGCQIQALSYEKQLEFKNNKVRNNLMRIGGFSEAKLDSKMQPP
CCCEEEECCCHHHHHCCCCCEEEEECCHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCCC
VGTDNPYRYRNKAQFPVGYDRDGNIVTGFYASRSHNIIPVEDCRLGVPQNKEILDIIKEW
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHHHCCCCCCCCHHHHHHHHHH
MNECGITPYDENTHKGLVRHVLIRYGFTSKQIMVCLVINGDSLEAKRRAGNAADILCERL
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHH
SKIDGMTSISYNINKENTNVILGKKTVCIWGRPYIEDTIHLLSYPDFTPQGTGITYQISP
HHHCCCEEEEEEECCCCCEEEEECEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECC
QSFYQVNPKQTEKLYSTALAFAGLTGNENVWDLYCGIGTISLFLSQKAKQVYGVEIVPQA
CCEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCEEEEHHH
IEDAKNNAKLNGITNAQFFVGKAEDVLPQFYENAKKKENITDDTASTGHTDMLRPDVIVV
HHCCCCCCEECCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
DPPRKGCDEKCLDTMLAMSPERIVYVSCDSATLARDLKILCEEKYELMKWQAFDQFSHTT
CCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HVESICLLERVSN
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]