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The map label for this gene is yegE [H]

Identifier: 238925257

GI number: 238925257

Start: 2787794

End: 2789572

Strand: Reverse

Name: yegE [H]

Synonym: EUBREC_2911

Alternate gene names: 238925257

Gene position: 2789572-2787794 (Counterclockwise)

Preceding gene: 238925258

Following gene: 238925254

Centisome position: 80.86

GC content: 42.95

Gene sequence:

>1779_bases
ATGAAAAAGCTAAAAAAGAGATTCATTATTCCGGCAGTGGTATTTATATTGGGCATGTGTGCGTTAATCGGCGCTATATA
TGTAGTCGGCAAGAGTCAGGAACAGCAGAACAGGACAAATGCAAAGCTCAATGCGATGACATATACGGAGCGTATATATG
GCGAGCTTATGGAGGGAATAGGAGTTACCGATAGCTTAAAGCAGGTTGTCATAAGTGGTGATGGAAATATAAATAGGTTT
TATGATATTGCAGCAAATATGATGGACGATTCGATTCAGAGTATACAGATAGCACCGAATGGAGTTGTGACTGAAATATA
TCCGGAGGAGAGTAATGAATCCAGTAAGATTGATCTGATAAATGATAGTGACAGGGGAGAGATTTCGCGCTATGCGAGGG
ATAATGACACTGTAATTATGCAGGGACCATTGGAGCTGAAGCAGGGCGGATATGGTATAGCAGTGCGCAATCCGGTTTAT
TTGGAGAATGAAAATGGTCAGAAGAGCTTTTGGGGCTTCACAATTGTTATACTGAAAGTTCCGGAAATTTTTTCTGAATC
TGTAGAGGCTCTTTCCAGTTTTGGATATAAGTACAGTCTGCAGAAGTTTGCTTCGCCGTGGGATGATACGTATGAGTGGG
TTTACGGTTCAAAGGAAGAGTTGAACAATCCGGTGATATATGACTTTAACGTGTATGGATACAAGTGGAGGCTTGAGATT
TTACCCAAGAGTGGGTTTTACAATAACAGATATCTGCTATATCTGTTCATCGGAGGTGGAGTTATTGTCCTGCTTTTGGC
AGGGCTTACAGCAGCGTTGATTTCAATCAATGAGAACAGGAAGAATTTCAAGAGACTGGCTGTGACCGATGCACTGACCG
GTATCTACAACAGGCACGGTTTTGATGAGCAGGTTGAGCAATATATGAGACAGAATCCGCAAAAGCATTGTGTTGTGGCA
ATGCTTGATATTGACGATTTCAAGCTGGTCAACGATGTGTATGGACATGCGGCAGGTGATGGTGCACTGCAGAAGCTTGC
AGAGAGCATGAAGCAATATTTTTCAAAGGATGTTATACTAGGCAGAAACGGAGGCGATGAGTTTAGCATTTTTATGCCGG
ATTGCACGGTAGAGGAGGTTAAGCCTTTTCTTAAGAAGTTTACAGGAGAAACCAAGAAATTTTATTGTAAAGGTGAAGAA
CATACATTTACCATTTCACTGGGCTTTGCGGAGTATCCTGTTTTGGCTGATGACCGTTCACAGCTCATGCGGTGTGCGGA
TATGGCACTTTATGAGGTGAAAATGCGTGGGAAGAACGGCTGCATGGCATACCGTGAGGGGGAGCGTATAAAGAGCCGTG
CGAAGCTTGGATTTGCCGTGAAAGATATTATTGACAATATGCCGGGTGCTTTCATTGTTTACAGGGCAGATAAAGAAAAT
GATGAGATTCTGCTTGCAAACAGCGAGCTGCTTCGGCTTACAGGCTGTAAAAACATGGATGAGCTGCTTGCATATACAGG
TAAGAGCTTCTGCAATCTGATACGCCCGGATGAACAGGAAAGCTGTCAAAAAAGCATATGGTCGCAGATTAACGGAGGAC
ACTCAAATGATTATATTTTCTTTCATATGCGAAAAGCAGACGGCACATATATTTCAGTGCTCAATCACGGCAGGATAGTG
GATTCAGTGCATAATGGCAGAGTATTTTATGTGATGATTATGGACTTAAAGTCACTGCAGAGGCACTATGGAGACTGCCT
GGAGCTGGTGGAGAAGTAG

Upstream 100 bases:

>100_bases
TGATATGAACTAAGTAAATTTATAGACATTTTCTTATCGTAAAGCTATAATATTAAAATCATATAGAACAGATAGACATT
GATTTTAGAAAGTGATACAA

Downstream 100 bases:

>100_bases
AAATAAGCAGATTGTGGACATATGAGTTCACAATCTGCTTTTTTAATAGTGCATACACAATTTATTTATCCGAATAAATC
ACATTTCCACCGCATACGGT

Product: sensory transduction protein kinase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MKKLKKRFIIPAVVFILGMCALIGAIYVVGKSQEQQNRTNAKLNAMTYTERIYGELMEGIGVTDSLKQVVISGDGNINRF
YDIAANMMDDSIQSIQIAPNGVVTEIYPEESNESSKIDLINDSDRGEISRYARDNDTVIMQGPLELKQGGYGIAVRNPVY
LENENGQKSFWGFTIVILKVPEIFSESVEALSSFGYKYSLQKFASPWDDTYEWVYGSKEELNNPVIYDFNVYGYKWRLEI
LPKSGFYNNRYLLYLFIGGGVIVLLLAGLTAALISINENRKNFKRLAVTDALTGIYNRHGFDEQVEQYMRQNPQKHCVVA
MLDIDDFKLVNDVYGHAAGDGALQKLAESMKQYFSKDVILGRNGGDEFSIFMPDCTVEEVKPFLKKFTGETKKFYCKGEE
HTFTISLGFAEYPVLADDRSQLMRCADMALYEVKMRGKNGCMAYREGERIKSRAKLGFAVKDIIDNMPGAFIVYRADKEN
DEILLANSELLRLTGCKNMDELLAYTGKSFCNLIRPDEQESCQKSIWSQINGGHSNDYIFFHMRKADGTYISVLNHGRIV
DSVHNGRVFYVMIMDLKSLQRHYGDCLELVEK

Sequences:

>Translated_592_residues
MKKLKKRFIIPAVVFILGMCALIGAIYVVGKSQEQQNRTNAKLNAMTYTERIYGELMEGIGVTDSLKQVVISGDGNINRF
YDIAANMMDDSIQSIQIAPNGVVTEIYPEESNESSKIDLINDSDRGEISRYARDNDTVIMQGPLELKQGGYGIAVRNPVY
LENENGQKSFWGFTIVILKVPEIFSESVEALSSFGYKYSLQKFASPWDDTYEWVYGSKEELNNPVIYDFNVYGYKWRLEI
LPKSGFYNNRYLLYLFIGGGVIVLLLAGLTAALISINENRKNFKRLAVTDALTGIYNRHGFDEQVEQYMRQNPQKHCVVA
MLDIDDFKLVNDVYGHAAGDGALQKLAESMKQYFSKDVILGRNGGDEFSIFMPDCTVEEVKPFLKKFTGETKKFYCKGEE
HTFTISLGFAEYPVLADDRSQLMRCADMALYEVKMRGKNGCMAYREGERIKSRAKLGFAVKDIIDNMPGAFIVYRADKEN
DEILLANSELLRLTGCKNMDELLAYTGKSFCNLIRPDEQESCQKSIWSQINGGHSNDYIFFHMRKADGTYISVLNHGRIV
DSVHNGRVFYVMIMDLKSLQRHYGDCLELVEK
>Mature_592_residues
MKKLKKRFIIPAVVFILGMCALIGAIYVVGKSQEQQNRTNAKLNAMTYTERIYGELMEGIGVTDSLKQVVISGDGNINRF
YDIAANMMDDSIQSIQIAPNGVVTEIYPEESNESSKIDLINDSDRGEISRYARDNDTVIMQGPLELKQGGYGIAVRNPVY
LENENGQKSFWGFTIVILKVPEIFSESVEALSSFGYKYSLQKFASPWDDTYEWVYGSKEELNNPVIYDFNVYGYKWRLEI
LPKSGFYNNRYLLYLFIGGGVIVLLLAGLTAALISINENRKNFKRLAVTDALTGIYNRHGFDEQVEQYMRQNPQKHCVVA
MLDIDDFKLVNDVYGHAAGDGALQKLAESMKQYFSKDVILGRNGGDEFSIFMPDCTVEEVKPFLKKFTGETKKFYCKGEE
HTFTISLGFAEYPVLADDRSQLMRCADMALYEVKMRGKNGCMAYREGERIKSRAKLGFAVKDIIDNMPGAFIVYRADKEN
DEILLANSELLRLTGCKNMDELLAYTGKSFCNLIRPDEQESCQKSIWSQINGGHSNDYIFFHMRKADGTYISVLNHGRIV
DSVHNGRVFYVMIMDLKSLQRHYGDCLELVEK

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=224, Percent_Identity=30.3571428571429, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787802, Length=189, Percent_Identity=32.2751322751323, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=27.3809523809524, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=32.2981366459627, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787541, Length=167, Percent_Identity=28.7425149700599, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=30.0613496932515, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=32.0754716981132, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081974, Length=120, Percent_Identity=35.8333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788085, Length=170, Percent_Identity=30.5882352941176, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081881, Length=169, Percent_Identity=28.9940828402367, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788956, Length=154, Percent_Identity=30.5194805194805, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081977, Length=184, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=28.3132530120482, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 67244; Mature: 67244

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50839 CHASE ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKKRFIIPAVVFILGMCALIGAIYVVGKSQEQQNRTNAKLNAMTYTERIYGELMEGI
CCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCEEEEHHHHHHHHHHHHHCC
GVTDSLKQVVISGDGNINRFYDIAANMMDDSIQSIQIAPNGVVTEIYPEESNESSKIDLI
CCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCCCEEEEE
NDSDRGEISRYARDNDTVIMQGPLELKQGGYGIAVRNPVYLENENGQKSFWGFTIVILKV
CCCCCCHHHHHCCCCCEEEEECCHHHCCCCEEEEECCCEEEECCCCCCEECEEEEEEEEC
PEIFSESVEALSSFGYKYSLQKFASPWDDTYEWVYGSKEELNNPVIYDFNVYGYKWRLEI
CHHHHHHHHHHHHCCCEEEHHHHCCCCCCCHHHHCCCHHHCCCCEEEEEEEEEEEEEEEE
LPKSGFYNNRYLLYLFIGGGVIVLLLAGLTAALISINENRKNFKRLAVTDALTGIYNRHG
EECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCC
FDEQVEQYMRQNPQKHCVVAMLDIDDFKLVNDVYGHAAGDGALQKLAESMKQYFSKDVIL
CHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEE
GRNGGDEFSIFMPDCTVEEVKPFLKKFTGETKKFYCKGEEHTFTISLGFAEYPVLADDRS
ECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCEECCCHH
QLMRCADMALYEVKMRGKNGCMAYREGERIKSRAKLGFAVKDIIDNMPGAFIVYRADKEN
HHHHHHHHHHEEEEECCCCCCEEECCCHHHHHHHHCCHHHHHHHHCCCCEEEEEEECCCC
DEILLANSELLRLTGCKNMDELLAYTGKSFCNLIRPDEQESCQKSIWSQINGGHSNDYIF
CCEEEECCCEEEEECCCCHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEE
FHMRKADGTYISVLNHGRIVDSVHNGRVFYVMIMDLKSLQRHYGDCLELVEK
EEEEECCCCEEEEEECCCEEECCCCCEEEEEEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLKKRFIIPAVVFILGMCALIGAIYVVGKSQEQQNRTNAKLNAMTYTERIYGELMEGI
CCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCEEEEHHHHHHHHHHHHHCC
GVTDSLKQVVISGDGNINRFYDIAANMMDDSIQSIQIAPNGVVTEIYPEESNESSKIDLI
CCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCCCEEEEE
NDSDRGEISRYARDNDTVIMQGPLELKQGGYGIAVRNPVYLENENGQKSFWGFTIVILKV
CCCCCCHHHHHCCCCCEEEEECCHHHCCCCEEEEECCCEEEECCCCCCEECEEEEEEEEC
PEIFSESVEALSSFGYKYSLQKFASPWDDTYEWVYGSKEELNNPVIYDFNVYGYKWRLEI
CHHHHHHHHHHHHCCCEEEHHHHCCCCCCCHHHHCCCHHHCCCCEEEEEEEEEEEEEEEE
LPKSGFYNNRYLLYLFIGGGVIVLLLAGLTAALISINENRKNFKRLAVTDALTGIYNRHG
EECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCC
FDEQVEQYMRQNPQKHCVVAMLDIDDFKLVNDVYGHAAGDGALQKLAESMKQYFSKDVIL
CHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEE
GRNGGDEFSIFMPDCTVEEVKPFLKKFTGETKKFYCKGEEHTFTISLGFAEYPVLADDRS
ECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCEECCCHH
QLMRCADMALYEVKMRGKNGCMAYREGERIKSRAKLGFAVKDIIDNMPGAFIVYRADKEN
HHHHHHHHHHEEEEECCCCCCEEECCCHHHHHHHHCCHHHHHHHHCCCCEEEEEEECCCC
DEILLANSELLRLTGCKNMDELLAYTGKSFCNLIRPDEQESCQKSIWSQINGGHSNDYIF
CCEEEECCCEEEEECCCCHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEE
FHMRKADGTYISVLNHGRIVDSVHNGRVFYVMIMDLKSLQRHYGDCLELVEK
EEEEECCCCEEEEEECCCEEECCCCCEEEEEEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]