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The map label for this gene is gufA [H]

Identifier: 238925250

GI number: 238925250

Start: 2781564

End: 2782343

Strand: Reverse

Name: gufA [H]

Synonym: EUBREC_2904

Alternate gene names: 238925250

Gene position: 2782343-2781564 (Counterclockwise)

Preceding gene: 238925251

Following gene: 238925249

Centisome position: 80.65

GC content: 46.92

Gene sequence:

>780_bases
ATGATTACATCAACCATATTAGGTTTATTAATACCATTTATAGGCACGTCGCTCGGTGCGGCATGTGTACTTTTTATGAA
AAATGAGCTTTCCGTAAAGACCACAAAAATGCTCAGTGGCTTTGCAGCAGGCGTAATGATTGCGGCATCAGTCTGGAGTC
TTCTGATTCCGGCACTTGAGCAGTCACAGAGCCTTGGAAAAATGCAGTTCGTCCCGGCAGTAGCAGGCTTTATGCTTGGA
ATGTTTTTCCTATTGATACTGGATACAATCACACCACATATGCATCTCGATAATTCAGTTGAGGGTCCAAAGAGCAATTT
AAGCAGACAGACAATGATGGTGCTTGCAGTTACATTACATAATATACCGGAGGGCATGGCAGTCGGAGTGCTCTACGCAA
GCTGGATATCAGGAAACACCACCATCACGAGGGCAGCAGCTCTTTCACTGGCAATCGGAATAGCTATACAGAATTTCCCG
GAGGGCGCAATCATATCCATGCCATTACATAGCACAGGAAGCTCAAAGCTAAGAGCCTTTGTATACGGAGTACTGTCGGG
AATAGTCGAGCCGATAGCGGGAATACTTACGATACTTGCCATCGGAATAATAGAGCCGGTGATGCCGTACCTGCTAAGCT
TCGCCGCCGGAGCCATGATATATGTAGTCATAGAAGAACTCGTGCCGGAAATGTCAGAAGGAGGTCACTCAAACCGCGCC
ACCATAGCATTTATGGTGGGCTTTTGCCTCATGATGACGCTCGATGTGATGCTGGGCTAG

Upstream 100 bases:

>100_bases
TTCTTCGGAACAACTGTATACTCTCCGGTAAATATAGTTTTATATATGGGAAGTTTGTGTAAAATAGAAAAACCGCAGAA
CAGCAGAATAGGAGGCAACC

Downstream 100 bases:

>100_bases
GCCAGAGCAAACCCTCGCAAAGAGCAAGAAAATCCAAGCGATCCCGCGGCAACAGCCGAGGGGAAAGCGTAAAAGAATAA
CAAACACGCACAGAGCGAGC

Product: zinc transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MITSTILGLLIPFIGTSLGAACVLFMKNELSVKTTKMLSGFAAGVMIAASVWSLLIPALEQSQSLGKMQFVPAVAGFMLG
MFFLLILDTITPHMHLDNSVEGPKSNLSRQTMMVLAVTLHNIPEGMAVGVLYASWISGNTTITRAAALSLAIGIAIQNFP
EGAIISMPLHSTGSSKLRAFVYGVLSGIVEPIAGILTILAIGIIEPVMPYLLSFAAGAMIYVVIEELVPEMSEGGHSNRA
TIAFMVGFCLMMTLDVMLG

Sequences:

>Translated_259_residues
MITSTILGLLIPFIGTSLGAACVLFMKNELSVKTTKMLSGFAAGVMIAASVWSLLIPALEQSQSLGKMQFVPAVAGFMLG
MFFLLILDTITPHMHLDNSVEGPKSNLSRQTMMVLAVTLHNIPEGMAVGVLYASWISGNTTITRAAALSLAIGIAIQNFP
EGAIISMPLHSTGSSKLRAFVYGVLSGIVEPIAGILTILAIGIIEPVMPYLLSFAAGAMIYVVIEELVPEMSEGGHSNRA
TIAFMVGFCLMMTLDVMLG
>Mature_259_residues
MITSTILGLLIPFIGTSLGAACVLFMKNELSVKTTKMLSGFAAGVMIAASVWSLLIPALEQSQSLGKMQFVPAVAGFMLG
MFFLLILDTITPHMHLDNSVEGPKSNLSRQTMMVLAVTLHNIPEGMAVGVLYASWISGNTTITRAAALSLAIGIAIQNFP
EGAIISMPLHSTGSSKLRAFVYGVLSGIVEPIAGILTILAIGIIEPVMPYLLSFAAGAMIYVVIEELVPEMSEGGHSNRA
TIAFMVGFCLMMTLDVMLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=155, Percent_Identity=49.0322580645161, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI229577422, Length=155, Percent_Identity=49.0322580645161, Blast_Score=155, Evalue=3e-38,
Organism=Escherichia coli, GI1789419, Length=258, Percent_Identity=29.8449612403101, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17507805, Length=303, Percent_Identity=39.6039603960396, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24652846, Length=168, Percent_Identity=47.0238095238095, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 27368; Mature: 27368

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
7.3 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSTILGLLIPFIGTSLGAACVLFMKNELSVKTTKMLSGFAAGVMIAASVWSLLIPALE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSQSLGKMQFVPAVAGFMLGMFFLLILDTITPHMHLDNSVEGPKSNLSRQTMMVLAVTLH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
NIPEGMAVGVLYASWISGNTTITRAAALSLAIGIAIQNFPEGAIISMPLHSTGSSKLRAF
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHH
VYGVLSGIVEPIAGILTILAIGIIEPVMPYLLSFAAGAMIYVVIEELVPEMSEGGHSNRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
TIAFMVGFCLMMTLDVMLG
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITSTILGLLIPFIGTSLGAACVLFMKNELSVKTTKMLSGFAAGVMIAASVWSLLIPALE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSQSLGKMQFVPAVAGFMLGMFFLLILDTITPHMHLDNSVEGPKSNLSRQTMMVLAVTLH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
NIPEGMAVGVLYASWISGNTTITRAAALSLAIGIAIQNFPEGAIISMPLHSTGSSKLRAF
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHH
VYGVLSGIVEPIAGILTILAIGIIEPVMPYLLSFAAGAMIYVVIEELVPEMSEGGHSNRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
TIAFMVGFCLMMTLDVMLG
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]