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The map label for this gene is atpB [H]

Identifier: 238925249

GI number: 238925249

Start: 2780009

End: 2780695

Strand: Reverse

Name: atpB [H]

Synonym: EUBREC_2903

Alternate gene names: 238925249

Gene position: 2780695-2780009 (Counterclockwise)

Preceding gene: 238925250

Following gene: 238925248

Centisome position: 80.61

GC content: 42.5

Gene sequence:

>687_bases
ATGGATGCTCTGGTAGATGGACTGTTAGAGGAACTCAATTGTGACGTGGTATTCAAGATACCGATATTCGGAGGCATACC
CATATACGAGTCGGTAGTAGTCACATGGATAATAATGGCAGCGGTATTTTTACTGTGCTTTTTTCTCGGCAGAAATCTTT
CAGTTGAAAATCCCGGACGCAGACAGGTAGCCGTAGAGGCAGGAGTCAAATTCCTTAATGATTTCTTCAGTGAGACACTC
GGAGAAAAAGGAAAGGATTACATACCATATCTGGCAACAGTAATCATCTATATAGGAATAGCAAACCTGATAGGATTACT
TGGCTTCAAACCGCCGACAAAGGATATGAACGTCACCGCAGCACTCGCTGTAATGAGCATAGTTCTTATCGAGGTGGCAG
GAATCAGGGCAAAGGGCACCAAAAGGTGGCTTAAAAGCTTTGCAGAGCCAATGCCGGTAATACTACCTATCAATATCCTT
GAGATCTTTATCAAACCATTATCGCTGTGTATGCGATTATTTGGAAACGTCCTTGGTTCATTCGTAATCATGGAGCTTTT
AAAGATGGTCGTACCGGCAATCGTCCCGGCAGTATTCAGTTGTTATTTTGATATCTTTGATGGACTTATACAGGCATATG
TATTTGTATTCCTGACAGGACTTTTCATCAAGGAGGCAACCGAGTAA

Upstream 100 bases:

>100_bases
TCAAACAAACATCAAAGGTCAGACAAAACACATCTTGAGTTATTAAGAAACAATTTGCGTATCAAATTTCATATAGCAAA
AAAGAAAGGAGGTAACGCAG

Downstream 100 bases:

>100_bases
GAAGACCTGATGAGGCATGAAACACCACATCATTTAATTTCACATCGTAAGCATGGAAAATGTAACCTCGCTTACAAAAG
AAACAAAATAATTGCTAACC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MDALVDGLLEELNCDVVFKIPIFGGIPIYESVVVTWIIMAAVFLLCFFLGRNLSVENPGRRQVAVEAGVKFLNDFFSETL
GEKGKDYIPYLATVIIYIGIANLIGLLGFKPPTKDMNVTAALAVMSIVLIEVAGIRAKGTKRWLKSFAEPMPVILPINIL
EIFIKPLSLCMRLFGNVLGSFVIMELLKMVVPAIVPAVFSCYFDIFDGLIQAYVFVFLTGLFIKEATE

Sequences:

>Translated_228_residues
MDALVDGLLEELNCDVVFKIPIFGGIPIYESVVVTWIIMAAVFLLCFFLGRNLSVENPGRRQVAVEAGVKFLNDFFSETL
GEKGKDYIPYLATVIIYIGIANLIGLLGFKPPTKDMNVTAALAVMSIVLIEVAGIRAKGTKRWLKSFAEPMPVILPINIL
EIFIKPLSLCMRLFGNVLGSFVIMELLKMVVPAIVPAVFSCYFDIFDGLIQAYVFVFLTGLFIKEATE
>Mature_228_residues
MDALVDGLLEELNCDVVFKIPIFGGIPIYESVVVTWIIMAAVFLLCFFLGRNLSVENPGRRQVAVEAGVKFLNDFFSETL
GEKGKDYIPYLATVIIYIGIANLIGLLGFKPPTKDMNVTAALAVMSIVLIEVAGIRAKGTKRWLKSFAEPMPVILPINIL
EIFIKPLSLCMRLFGNVLGSFVIMELLKMVVPAIVPAVFSCYFDIFDGLIQAYVFVFLTGLFIKEATE

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=198, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 25197; Mature: 25197

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALVDGLLEELNCDVVFKIPIFGGIPIYESVVVTWIIMAAVFLLCFFLGRNLSVENPGR
CHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
RQVAVEAGVKFLNDFFSETLGEKGKDYIPYLATVIIYIGIANLIGLLGFKPPTKDMNVTA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
ALAVMSIVLIEVAGIRAKGTKRWLKSFAEPMPVILPINILEIFIKPLSLCMRLFGNVLGS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FVIMELLKMVVPAIVPAVFSCYFDIFDGLIQAYVFVFLTGLFIKEATE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDALVDGLLEELNCDVVFKIPIFGGIPIYESVVVTWIIMAAVFLLCFFLGRNLSVENPGR
CHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
RQVAVEAGVKFLNDFFSETLGEKGKDYIPYLATVIIYIGIANLIGLLGFKPPTKDMNVTA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
ALAVMSIVLIEVAGIRAKGTKRWLKSFAEPMPVILPINILEIFIKPLSLCMRLFGNVLGS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FVIMELLKMVVPAIVPAVFSCYFDIFDGLIQAYVFVFLTGLFIKEATE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10902917; 11466286 [H]