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The map label for this gene is yesM [H]

Identifier: 238925234

GI number: 238925234

Start: 2767337

End: 2768488

Strand: Reverse

Name: yesM [H]

Synonym: EUBREC_2888

Alternate gene names: 238925234

Gene position: 2768488-2767337 (Counterclockwise)

Preceding gene: 238925235

Following gene: 238925233

Centisome position: 80.25

GC content: 38.8

Gene sequence:

>1152_bases
ATGGAGATGGATGAAAATGGCATTGTGCAGTACAGCAATAATCCGGTGATTGTCCGGGGCCAAAAGATTTTGTCGGAATT
ACCGAAAAAAGAAGGATATGCTGTAACAAATCAGGAAGGATATAAAATCATGGTGTATCGCAGTACCATTGGATATGCCA
ATGCCATTGCACTGCCGGAAAATATCTATCAGAAAGAAATGAATATGTGGAGATTGAAGCTGGTGGTTATCATTCTGTCA
GCATTCGGTATTTTTTCCTGTTCTGTTATTTACCTGTACAGGTTGATATGCAAACCACTTAATCAGTTACAAAAACAGAT
TATCCAGGTAGGAAATGGGGCATTACATGGAGAAAGGCAGGAATATGAGATCAAGGAATTTGATGACTTGATGCACGAAG
TGGAGCAGATGAAGGAACAAATCAGAAATCTGATTGATGATGTTGTGGAAAAAGAAAAAAATATTCAGCGGACGGAATAT
GAGAAGCTTCTGTATCAGATCAATCCTCATTTTCTGCTCAATACACTAAATTCTGTTCAGTGGATGGCCAGAATGAGCAA
ACAGAATAATATTATGGAATTTGTGCAGCGATTAAAAAGACTGTTGTCCTACAATCTGGGAAAAGAGGGAATGCAGACGA
CACTTCGAACAGAAATCGATATTGTGAAAGATTATATAGCATTGGAACAGATGCGTTACGATTTTGTGATTGAGATGAAT
GTGGAAGAGGGGCGTTATCTGGAACAGCCGACGGTAAGGATGCTGCTGCAGCCACTGGTAGAAAATGCCATACGATATGG
ACTTGGAAATGATGAAAAGATCACAATTCAGGTCTTTGAGGATAATATCAGGGGACTGGCGGGCATCACCATATTAGACA
GCGGTAATGGTCTGACCCAGGAGGAAATTTATCAGATCAATGAACCATTTGACTACGATGTAAAAAAAATGCAACATGGA
AACAGAGGAATCGGTCTGCGATATGTAAAAGCAATGTTGGACTCTTTTTATGAAGGAGAAACGACTCTGTTTGTAAATTG
CAAAAAAGGATATGGAACCAAAATTACAATTTTGATTCCGATTCAGGAAGAACTTCGGAACAAAATAAAAATTACAGGAG
TTGAGACAGAAAAAGAAGGTAAGGAGAAATGA

Upstream 100 bases:

>100_bases
TTCTTTTGGTAACCAAAAGATGCTGGATATTTATGCAGAAATTGAGCCTGATATGAGTGTTTCAGATCAGCTTAATAAAG
AAAAATGACCATATACCTAT

Downstream 100 bases:

>100_bases
AAGTATTAGTTGTTGACGATGATAAACTGGCAAGAAAAGGTTTGATCTCCATAATGGATTGGAAGAAATACGGATTTGAA
GTTGTGGGGGATGTTCAGAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MEMDENGIVQYSNNPVIVRGQKILSELPKKEGYAVTNQEGYKIMVYRSTIGYANAIALPENIYQKEMNMWRLKLVVIILS
AFGIFSCSVIYLYRLICKPLNQLQKQIIQVGNGALHGERQEYEIKEFDDLMHEVEQMKEQIRNLIDDVVEKEKNIQRTEY
EKLLYQINPHFLLNTLNSVQWMARMSKQNNIMEFVQRLKRLLSYNLGKEGMQTTLRTEIDIVKDYIALEQMRYDFVIEMN
VEEGRYLEQPTVRMLLQPLVENAIRYGLGNDEKITIQVFEDNIRGLAGITILDSGNGLTQEEIYQINEPFDYDVKKMQHG
NRGIGLRYVKAMLDSFYEGETTLFVNCKKGYGTKITILIPIQEELRNKIKITGVETEKEGKEK

Sequences:

>Translated_383_residues
MEMDENGIVQYSNNPVIVRGQKILSELPKKEGYAVTNQEGYKIMVYRSTIGYANAIALPENIYQKEMNMWRLKLVVIILS
AFGIFSCSVIYLYRLICKPLNQLQKQIIQVGNGALHGERQEYEIKEFDDLMHEVEQMKEQIRNLIDDVVEKEKNIQRTEY
EKLLYQINPHFLLNTLNSVQWMARMSKQNNIMEFVQRLKRLLSYNLGKEGMQTTLRTEIDIVKDYIALEQMRYDFVIEMN
VEEGRYLEQPTVRMLLQPLVENAIRYGLGNDEKITIQVFEDNIRGLAGITILDSGNGLTQEEIYQINEPFDYDVKKMQHG
NRGIGLRYVKAMLDSFYEGETTLFVNCKKGYGTKITILIPIQEELRNKIKITGVETEKEGKEK
>Mature_383_residues
MEMDENGIVQYSNNPVIVRGQKILSELPKKEGYAVTNQEGYKIMVYRSTIGYANAIALPENIYQKEMNMWRLKLVVIILS
AFGIFSCSVIYLYRLICKPLNQLQKQIIQVGNGALHGERQEYEIKEFDDLMHEVEQMKEQIRNLIDDVVEKEKNIQRTEY
EKLLYQINPHFLLNTLNSVQWMARMSKQNNIMEFVQRLKRLLSYNLGKEGMQTTLRTEIDIVKDYIALEQMRYDFVIEMN
VEEGRYLEQPTVRMLLQPLVENAIRYGLGNDEKITIQVFEDNIRGLAGITILDSGNGLTQEEIYQINEPFDYDVKKMQHG
NRGIGLRYVKAMLDSFYEGETTLFVNCKKGYGTKITILIPIQEELRNKIKITGVETEKEGKEK

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=156, Percent_Identity=32.0512820512821, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788446, Length=217, Percent_Identity=27.6497695852535, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44672; Mature: 44672

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMDENGIVQYSNNPVIVRGQKILSELPKKEGYAVTNQEGYKIMVYRSTIGYANAIALPE
CCCCCCCCEEECCCCEEEECHHHHHHCCCCCCCEEECCCCCEEEEEEECCCCCHHCCCCH
NIYQKEMNMWRLKLVVIILSAFGIFSCSVIYLYRLICKPLNQLQKQIIQVGNGALHGERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EYEIKEFDDLMHEVEQMKEQIRNLIDDVVEKEKNIQRTEYEKLLYQINPHFLLNTLNSVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
WMARMSKQNNIMEFVQRLKRLLSYNLGKEGMQTTLRTEIDIVKDYIALEQMRYDFVIEMN
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEE
VEEGRYLEQPTVRMLLQPLVENAIRYGLGNDEKITIQVFEDNIRGLAGITILDSGNGLTQ
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCH
EEIYQINEPFDYDVKKMQHGNRGIGLRYVKAMLDSFYEGETTLFVNCKKGYGTKITILIP
HHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEE
IQEELRNKIKITGVETEKEGKEK
CHHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MEMDENGIVQYSNNPVIVRGQKILSELPKKEGYAVTNQEGYKIMVYRSTIGYANAIALPE
CCCCCCCCEEECCCCEEEECHHHHHHCCCCCCCEEECCCCCEEEEEEECCCCCHHCCCCH
NIYQKEMNMWRLKLVVIILSAFGIFSCSVIYLYRLICKPLNQLQKQIIQVGNGALHGERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EYEIKEFDDLMHEVEQMKEQIRNLIDDVVEKEKNIQRTEYEKLLYQINPHFLLNTLNSVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
WMARMSKQNNIMEFVQRLKRLLSYNLGKEGMQTTLRTEIDIVKDYIALEQMRYDFVIEMN
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEE
VEEGRYLEQPTVRMLLQPLVENAIRYGLGNDEKITIQVFEDNIRGLAGITILDSGNGLTQ
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCH
EEIYQINEPFDYDVKKMQHGNRGIGLRYVKAMLDSFYEGETTLFVNCKKGYGTKITILIP
HHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEE
IQEELRNKIKITGVETEKEGKEK
CHHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]