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The map label for this gene is dnaG [H]

Identifier: 238925053

GI number: 238925053

Start: 2575572

End: 2576216

Strand: Direct

Name: dnaG [H]

Synonym: EUBREC_2705

Alternate gene names: 238925053

Gene position: 2575572-2576216 (Clockwise)

Preceding gene: 238925052

Following gene: 238925054

Centisome position: 74.66

GC content: 53.8

Gene sequence:

>645_bases
TTGAATGTATTTGAAGCTGTGAAGCAGTCCGTCACAACAAGACAGGCTGCGGAGCATTATGGAATCCATGCAGGGCGGAA
CGGGATGGCTTGCTGCCCGTTCCATCACGATAAAACCCCAAGCATGAAGCTGGATCAGCGTTACCACTGCTTCGGCTGCG
GTGCGGATGGGGATGTGATTGATTTTGCCGCCGCCCTGTATGGGCTGGGAAAGAAAGAAGCCGCCGTACAACTGGCACAG
GACTTCGGGCTTTCCTATGAGGACTGGAAGCCGCCGGGAAAGGCAAAAAAGCCCAAGCCCCGGCAGAAATCCCCGGAGGA
ACAGTTTCAGGAAGCAAAGAGCCGCTGCTTCCGTATCCTTGCCGATTATCTCCATCTGCTTCGGGCATGGAGAAAGGAAT
ATGCCCCGCACTCCCCGGAGGAAGCCTTTCATCCCCGGTTTGTGGAAGCCTTACAGAAGCAAGACCATGTGGAATATCTG
CTGGATGTGCTGCTCTTTGGGGAGACAGAGGAAAAAGCAGCTTTGATTACGGACTACGGAAAGGATGTGATACAGCTTGA
AAAGCGAATGGCAGAGCTTGCCGCCGCAAACGCAGCAAGAACTAAAAAACACCATGAACGCCATGCAGCCGCCCCAGAGC
ATTGA

Upstream 100 bases:

>100_bases
GCAGACGAAACACAGACAACAGGATATGGAACTTTAACAGACACTTGCCATTTTCAATCAGAGAATGTCAGGTGCTTTTT
CTTTTTAAGGAGGGATAGAT

Downstream 100 bases:

>100_bases
GGAAATCAAGGCGGGGCTGGAAACTACCGAGAAAGGCGGTGTCCGTCAGAGCATACGGAACTGCCTGACCGTATTCCAGC
GTGACCCGCTGCTTTCCGGG

Product: DNA primase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNVFEAVKQSVTTRQAAEHYGIHAGRNGMACCPFHHDKTPSMKLDQRYHCFGCGADGDVIDFAAALYGLGKKEAAVQLAQ
DFGLSYEDWKPPGKAKKPKPRQKSPEEQFQEAKSRCFRILADYLHLLRAWRKEYAPHSPEEAFHPRFVEALQKQDHVEYL
LDVLLFGETEEKAALITDYGKDVIQLEKRMAELAAANAARTKKHHERHAAAPEH

Sequences:

>Translated_214_residues
MNVFEAVKQSVTTRQAAEHYGIHAGRNGMACCPFHHDKTPSMKLDQRYHCFGCGADGDVIDFAAALYGLGKKEAAVQLAQ
DFGLSYEDWKPPGKAKKPKPRQKSPEEQFQEAKSRCFRILADYLHLLRAWRKEYAPHSPEEAFHPRFVEALQKQDHVEYL
LDVLLFGETEEKAALITDYGKDVIQLEKRMAELAAANAARTKKHHERHAAAPEH
>Mature_214_residues
MNVFEAVKQSVTTRQAAEHYGIHAGRNGMACCPFHHDKTPSMKLDQRYHCFGCGADGDVIDFAAALYGLGKKEAAVQLAQ
DFGLSYEDWKPPGKAKKPKPRQKSPEEQFQEAKSRCFRILADYLHLLRAWRKEYAPHSPEEAFHPRFVEALQKQDHVEYL
LDVLLFGETEEKAALITDYGKDVIQLEKRMAELAAANAARTKKHHERHAAAPEH

Specific function: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis [H]

COG id: COG0358

COG function: function code L; DNA primase (bacterial type)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013264
- InterPro:   IPR006295
- InterPro:   IPR006171
- InterPro:   IPR002694 [H]

Pfam domain/function: PF01751 Toprim; PF08275 Toprim_N; PF01807 zf-CHC2 [H]

EC number: 2.7.7.-

Molecular weight: Translated: 24283; Mature: 24283

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFEAVKQSVTTRQAAEHYGIHAGRNGMACCPFHHDKTPSMKLDQRYHCFGCGADGDVI
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCHHH
DFAAALYGLGKKEAAVQLAQDFGLSYEDWKPPGKAKKPKPRQKSPEEQFQEAKSRCFRIL
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ADYLHLLRAWRKEYAPHSPEEAFHPRFVEALQKQDHVEYLLDVLLFGETEEKAALITDYG
HHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KDVIQLEKRMAELAAANAARTKKHHERHAAAPEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNVFEAVKQSVTTRQAAEHYGIHAGRNGMACCPFHHDKTPSMKLDQRYHCFGCGADGDVI
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCHHH
DFAAALYGLGKKEAAVQLAQDFGLSYEDWKPPGKAKKPKPRQKSPEEQFQEAKSRCFRIL
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ADYLHLLRAWRKEYAPHSPEEAFHPRFVEALQKQDHVEYLLDVLLFGETEEKAALITDYG
HHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KDVIQLEKRMAELAAANAARTKKHHERHAAAPEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Nucleotidyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422995; 9823893 [H]