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The map label for this gene is aroH [H]

Identifier: 238924580

GI number: 238924580

Start: 2076282

End: 2077313

Strand: Direct

Name: aroH [H]

Synonym: EUBREC_2223

Alternate gene names: 238924580

Gene position: 2076282-2077313 (Clockwise)

Preceding gene: 238924562

Following gene: 238924597

Centisome position: 60.19

GC content: 46.51

Gene sequence:

>1032_bases
ATGAGTTTCACATTTTTAAACCAGCTTCCAACTCCTGCACAGATTAAGGAGGAATATCCTCTGTCAAAGGAGCTTACCGA
GCTTAAAGCGAAGCGCGATGCAATGATTTCAGATGTTATCTGCGGAAAAGATGATAGATTTCTCGTCATTATCGGACCTT
GTTCAGCCGACAACGAGGATTCAGTCTGTGACTATGTCAGCCGTCTGACAAAGATTCAGGAGGATGTAAAGGACCGCGTA
ATCATCATCCCTCGTGTATATACAAACAAGCCAAGAACAACCGGCGAGGGCTACAAGGGAATTGCCTCACAGCCTGACCC
TGAGAAGGCTCCTGACATGGTTGAGGGTCTTATCGCCATGAGAAAAATGCACATCCGTGCCATCGCAGAGAGTGGACTCA
CCTGTGCAGATGAGATGCTTTACCCTGAGAACTGGGGCTATGTTGAGGATCTTCTCTCATATGTGGCAATCGGTGCTCGT
TCTGTTGAGGATCAACAGCATCGTCTCACCGTCAGCGGCTTCGATGTGGCCAGCGGCATGAAAAACCCTACAAGCGGTGA
TTTTTCCGTCATGCTCAATTCTGTTTACGCAGCACAGCACCCACATCATTTTGTTTACAGAGGCTATGAGGTTGAGACAT
CAGGAAATCCTCTGACTCACGTTGTTTTAAGAGGTGCTGTCAGCAAGCATGGCAACACTACAACAAACTACCATTACGAG
GACTTAATCCGTCTGCACGAAATGTACGACAAGATGGACGTTGTCAACCAGGCGGCTATCATCGATACTAACCATTCCAA
CTCCGGAAAGAAGTTCAAGGAGCAGATTCGTATCGCCAAGGAAGTTATGCACAACAGACAGCTTTCCTCTGATATCAAAT
CACTTGTCAAGGGTCTTATGATTGAGAGCTATATCGAGGAGGGCAGCCAGAAGATTGGTGAGCATGTCTACGGAAAATCC
ATCACCGATCCATGTCTAGGATGGGAGGATTCAAAGAAGCTTATCTACGACATTGCAGAAATGAATTCTTAA

Upstream 100 bases:

>100_bases
TTAACTGTTTGGGCATTATATATTGGAAATTTTTTCCGATATGCCATAAAAATATACCATTTTAATTAATACAATTACTA
TTTATATAAGGAGCAGTATT

Downstream 100 bases:

>100_bases
ACCACAAATTATACATACATTTTTTTACAAAACACAAGCCACAGGAGTATATATCCTGTGGCTTGCATTATTTTGTCGGT
TTATTATTTAATCATATTAC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSFTFLNQLPTPAQIKEEYPLSKELTELKAKRDAMISDVICGKDDRFLVIIGPCSADNEDSVCDYVSRLTKIQEDVKDRV
IIIPRVYTNKPRTTGEGYKGIASQPDPEKAPDMVEGLIAMRKMHIRAIAESGLTCADEMLYPENWGYVEDLLSYVAIGAR
SVEDQQHRLTVSGFDVASGMKNPTSGDFSVMLNSVYAAQHPHHFVYRGYEVETSGNPLTHVVLRGAVSKHGNTTTNYHYE
DLIRLHEMYDKMDVVNQAAIIDTNHSNSGKKFKEQIRIAKEVMHNRQLSSDIKSLVKGLMIESYIEEGSQKIGEHVYGKS
ITDPCLGWEDSKKLIYDIAEMNS

Sequences:

>Translated_343_residues
MSFTFLNQLPTPAQIKEEYPLSKELTELKAKRDAMISDVICGKDDRFLVIIGPCSADNEDSVCDYVSRLTKIQEDVKDRV
IIIPRVYTNKPRTTGEGYKGIASQPDPEKAPDMVEGLIAMRKMHIRAIAESGLTCADEMLYPENWGYVEDLLSYVAIGAR
SVEDQQHRLTVSGFDVASGMKNPTSGDFSVMLNSVYAAQHPHHFVYRGYEVETSGNPLTHVVLRGAVSKHGNTTTNYHYE
DLIRLHEMYDKMDVVNQAAIIDTNHSNSGKKFKEQIRIAKEVMHNRQLSSDIKSLVKGLMIESYIEEGSQKIGEHVYGKS
ITDPCLGWEDSKKLIYDIAEMNS
>Mature_342_residues
SFTFLNQLPTPAQIKEEYPLSKELTELKAKRDAMISDVICGKDDRFLVIIGPCSADNEDSVCDYVSRLTKIQEDVKDRVI
IIPRVYTNKPRTTGEGYKGIASQPDPEKAPDMVEGLIAMRKMHIRAIAESGLTCADEMLYPENWGYVEDLLSYVAIGARS
VEDQQHRLTVSGFDVASGMKNPTSGDFSVMLNSVYAAQHPHHFVYRGYEVETSGNPLTHVVLRGAVSKHGNTTTNYHYED
LIRLHEMYDKMDVVNQAAIIDTNHSNSGKKFKEQIRIAKEVMHNRQLSSDIKSLVKGLMIESYIEEGSQKIGEHVYGKSI
TDPCLGWEDSKKLIYDIAEMNS

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=342, Percent_Identity=35.9649122807018, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1788953, Length=339, Percent_Identity=35.1032448377581, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1787996, Length=342, Percent_Identity=32.1637426900585, Blast_Score=186, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320240, Length=346, Percent_Identity=35.2601156069364, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6319726, Length=343, Percent_Identity=34.9854227405248, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38573; Mature: 38442

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTFLNQLPTPAQIKEEYPLSKELTELKAKRDAMISDVICGKDDRFLVIIGPCSADNED
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
SVCDYVSRLTKIQEDVKDRVIIIPRVYTNKPRTTGEGYKGIASQPDPEKAPDMVEGLIAM
HHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RKMHIRAIAESGLTCADEMLYPENWGYVEDLLSYVAIGARSVEDQQHRLTVSGFDVASGM
HHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHEEEECCCHHHCCC
KNPTSGDFSVMLNSVYAAQHPHHFVYRGYEVETSGNPLTHVVLRGAVSKHGNTTTNYHYE
CCCCCCHHHHHHHHHHHHCCCCEEEEECEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHH
DLIRLHEMYDKMDVVNQAAIIDTNHSNSGKKFKEQIRIAKEVMHNRQLSSDIKSLVKGLM
HHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESYIEEGSQKIGEHVYGKSITDPCLGWEDSKKLIYDIAEMNS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SFTFLNQLPTPAQIKEEYPLSKELTELKAKRDAMISDVICGKDDRFLVIIGPCSADNED
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
SVCDYVSRLTKIQEDVKDRVIIIPRVYTNKPRTTGEGYKGIASQPDPEKAPDMVEGLIAM
HHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RKMHIRAIAESGLTCADEMLYPENWGYVEDLLSYVAIGARSVEDQQHRLTVSGFDVASGM
HHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHEEEECCCHHHCCC
KNPTSGDFSVMLNSVYAAQHPHHFVYRGYEVETSGNPLTHVVLRGAVSKHGNTTTNYHYE
CCCCCCHHHHHHHHHHHHCCCCEEEEECEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHH
DLIRLHEMYDKMDVVNQAAIIDTNHSNSGKKFKEQIRIAKEVMHNRQLSSDIKSLVKGLM
HHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESYIEEGSQKIGEHVYGKSITDPCLGWEDSKKLIYDIAEMNS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9422601 [H]