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The map label for this gene is cvrA [H]

Identifier: 238924562

GI number: 238924562

Start: 2057605

End: 2059203

Strand: Direct

Name: cvrA [H]

Synonym: EUBREC_2204

Alternate gene names: 238924562

Gene position: 2057605-2059203 (Clockwise)

Preceding gene: 238924560

Following gene: 238924580

Centisome position: 59.65

GC content: 43.71

Gene sequence:

>1599_bases
ATGAATACATACCTGCTCATCACATCTATAGTAATCTTCTTATGTATCCTGCTAAATCGTGTCTCCAACCGCATAGGCAT
TCCGGCACTTTTAGCCTTTATCGTGCTCGGCATGCTTTTTGGCTCTGACGGAATAATGAAGATAGATTTCGACAATTACG
CGTTCGCTGAACAGATATGCTCTACCGCGCTGATTTTTATCATGTTCTATGGCGGCTTTGGCACCAACTGGCAGCGTGCA
AAGGCTGTTGCCGTTAAGTCTGTACTTTTGTCCACCATCGGTGTTATTATCACATGCTTTCTCACAGGGCTGTTCTGTCA
CTTTGCCCTTAATATGATCTGGGAAATAAGCTTTCTCCTCGGTGCGCTGATTTCATCAACTGATGCGGCGAGCGTTTTCT
CCATACTGCGTTCGAAAAAGCTGAATCTGAAATACAATACCGCCTCTCTTCTTGAAGTGGAAAGCGGTAGTAATGACCCA
TGTGCCTATATGCTCACAGTTGCTTTTATAGCCATATCCCAGGGCAGCGCAAGCCCTGGAAATATTGCCATACTCATAGT
AAAGCAGCTTGCCTTCGGCATAATCTTCGGCGTCCTGATTGCAAAGCTTTCCATCATGCTCCTTCGATATATACGCTTCA
AAAGCGCGGGGTTTGATGCGATTTTCATGGTGGGAATAGCTATAATATCATATGCCCTGCCTGCTTACTTTGACGGAAAC
GGCTTCTTAAGCGCCTATATAGTCGGCATTATACTCGGCAACACAGAAATAGAAAATAAAAAGAATCTGGTGAATTTCTT
TGATGGCATAACAGGACTCATGCAGATGCTTATTTTCTTTCTGCTTGGTCTGCTTTCTTTCCCATCAAAGCTGCCACACG
TCATAGTACCGGCACTTTTAATATTTATGTGGCTGACCTTTGTGGCAAGACCTCTTTCTGTCGCACTTGTGCTCACACCA
TTTCGCAGCAAAATAAAACAGCAGCTGCTTGTCTCATGGTCCGGCTTAAGAGGAGCCGCATCCATAGTGTTTTCCATCAT
GGCATATACCGCCACCAATGATGACCTCGACACCTTCCACATAATATTTATGATAGTACTCTTTTCAATACTGCTTCAGG
GCTCAATGCTCCCATGGATATCGCGAAAGCTTGATATGCTCGATAAAACAGCCGATGTAATGAAGACCTTCAATGATTAC
TCCGAGGAAGCAGACATCCAGTTCATACAGCTTACCATACCGGAAAATCATCTGTGGTGTGGCCACAAGCTAAAGGACCT
GACGCTGCCTCCTGAGACACTGATTGTGCTTATACGAAGAGGTGAGCAGAATATAATACCGGACGGTGAAACAATAATTC
TGCAAAATGATGTGCTCGTGCTTAGTGCCATCACACCTGATGAGGTGCATGGTATAAAACTGGTGGAAAAAATAATAGAA
AAAGACAGCAGATATAACAATAAACTGCTGTCTGAAATATCAAAAAAACACAATGAGATTATAATAATGATCCAAAGAAA
TGGGCAGGTAATCATCCCAAACGGAAACGTACGGCTGACCACCGGTGATATACTGGTAATCAACCGCGCCGTAAACTGA

Upstream 100 bases:

>100_bases
TATTATAAATTTCACATATAATTCCCACGTTGTCCGTTACAAATAAATACTGTAATAGCTTTATAATTCTTAAATCACCA
TTTAATAAAGGAGGGATTCC

Downstream 100 bases:

>100_bases
TAATGTCAGATTTTTTTCTCCATGGCAAGTGCTTTCATCTCGCGTGCGCTCTCCATCACGGTATCTGTGATTTTTGCACC
GCCGAGCATTCTGGCAAGTT

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MNTYLLITSIVIFLCILLNRVSNRIGIPALLAFIVLGMLFGSDGIMKIDFDNYAFAEQICSTALIFIMFYGGFGTNWQRA
KAVAVKSVLLSTIGVIITCFLTGLFCHFALNMIWEISFLLGALISSTDAASVFSILRSKKLNLKYNTASLLEVESGSNDP
CAYMLTVAFIAISQGSASPGNIAILIVKQLAFGIIFGVLIAKLSIMLLRYIRFKSAGFDAIFMVGIAIISYALPAYFDGN
GFLSAYIVGIILGNTEIENKKNLVNFFDGITGLMQMLIFFLLGLLSFPSKLPHVIVPALLIFMWLTFVARPLSVALVLTP
FRSKIKQQLLVSWSGLRGAASIVFSIMAYTATNDDLDTFHIIFMIVLFSILLQGSMLPWISRKLDMLDKTADVMKTFNDY
SEEADIQFIQLTIPENHLWCGHKLKDLTLPPETLIVLIRRGEQNIIPDGETIILQNDVLVLSAITPDEVHGIKLVEKIIE
KDSRYNNKLLSEISKKHNEIIIMIQRNGQVIIPNGNVRLTTGDILVINRAVN

Sequences:

>Translated_532_residues
MNTYLLITSIVIFLCILLNRVSNRIGIPALLAFIVLGMLFGSDGIMKIDFDNYAFAEQICSTALIFIMFYGGFGTNWQRA
KAVAVKSVLLSTIGVIITCFLTGLFCHFALNMIWEISFLLGALISSTDAASVFSILRSKKLNLKYNTASLLEVESGSNDP
CAYMLTVAFIAISQGSASPGNIAILIVKQLAFGIIFGVLIAKLSIMLLRYIRFKSAGFDAIFMVGIAIISYALPAYFDGN
GFLSAYIVGIILGNTEIENKKNLVNFFDGITGLMQMLIFFLLGLLSFPSKLPHVIVPALLIFMWLTFVARPLSVALVLTP
FRSKIKQQLLVSWSGLRGAASIVFSIMAYTATNDDLDTFHIIFMIVLFSILLQGSMLPWISRKLDMLDKTADVMKTFNDY
SEEADIQFIQLTIPENHLWCGHKLKDLTLPPETLIVLIRRGEQNIIPDGETIILQNDVLVLSAITPDEVHGIKLVEKIIE
KDSRYNNKLLSEISKKHNEIIIMIQRNGQVIIPNGNVRLTTGDILVINRAVN
>Mature_532_residues
MNTYLLITSIVIFLCILLNRVSNRIGIPALLAFIVLGMLFGSDGIMKIDFDNYAFAEQICSTALIFIMFYGGFGTNWQRA
KAVAVKSVLLSTIGVIITCFLTGLFCHFALNMIWEISFLLGALISSTDAASVFSILRSKKLNLKYNTASLLEVESGSNDP
CAYMLTVAFIAISQGSASPGNIAILIVKQLAFGIIFGVLIAKLSIMLLRYIRFKSAGFDAIFMVGIAIISYALPAYFDGN
GFLSAYIVGIILGNTEIENKKNLVNFFDGITGLMQMLIFFLLGLLSFPSKLPHVIVPALLIFMWLTFVARPLSVALVLTP
FRSKIKQQLLVSWSGLRGAASIVFSIMAYTATNDDLDTFHIIFMIVLFSILLQGSMLPWISRKLDMLDKTADVMKTFNDY
SEEADIQFIQLTIPENHLWCGHKLKDLTLPPETLIVLIRRGEQNIIPDGETIILQNDVLVLSAITPDEVHGIKLVEKIIE
KDSRYNNKLLSEISKKHNEIIIMIQRNGQVIIPNGNVRLTTGDILVINRAVN

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=491, Percent_Identity=34.4195519348269, Blast_Score=240, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 58988; Mature: 58988

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTYLLITSIVIFLCILLNRVSNRIGIPALLAFIVLGMLFGSDGIMKIDFDNYAFAEQIC
CCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
STALIFIMFYGGFGTNWQRAKAVAVKSVLLSTIGVIITCFLTGLFCHFALNMIWEISFLL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALISSTDAASVFSILRSKKLNLKYNTASLLEVESGSNDPCAYMLTVAFIAISQGSASPG
HHHHCCCCHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
NIAILIVKQLAFGIIFGVLIAKLSIMLLRYIRFKSAGFDAIFMVGIAIISYALPAYFDGN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEECCC
GFLSAYIVGIILGNTEIENKKNLVNFFDGITGLMQMLIFFLLGLLSFPSKLPHVIVPALL
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IFMWLTFVARPLSVALVLTPFRSKIKQQLLVSWSGLRGAASIVFSIMAYTATNDDLDTFH
HHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHH
IIFMIVLFSILLQGSMLPWISRKLDMLDKTADVMKTFNDYSEEADIQFIQLTIPENHLWC
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEC
GHKLKDLTLPPETLIVLIRRGEQNIIPDGETIILQNDVLVLSAITPDEVHGIKLVEKIIE
CCCCCCCCCCHHHHEEEEECCCCCCCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHH
KDSRYNNKLLSEISKKHNEIIIMIQRNGQVIIPNGNVRLTTGDILVINRAVN
HCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEECCEEEEEECCC
>Mature Secondary Structure
MNTYLLITSIVIFLCILLNRVSNRIGIPALLAFIVLGMLFGSDGIMKIDFDNYAFAEQIC
CCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
STALIFIMFYGGFGTNWQRAKAVAVKSVLLSTIGVIITCFLTGLFCHFALNMIWEISFLL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALISSTDAASVFSILRSKKLNLKYNTASLLEVESGSNDPCAYMLTVAFIAISQGSASPG
HHHHCCCCHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
NIAILIVKQLAFGIIFGVLIAKLSIMLLRYIRFKSAGFDAIFMVGIAIISYALPAYFDGN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEECCC
GFLSAYIVGIILGNTEIENKKNLVNFFDGITGLMQMLIFFLLGLLSFPSKLPHVIVPALL
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IFMWLTFVARPLSVALVLTPFRSKIKQQLLVSWSGLRGAASIVFSIMAYTATNDDLDTFH
HHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHH
IIFMIVLFSILLQGSMLPWISRKLDMLDKTADVMKTFNDYSEEADIQFIQLTIPENHLWC
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEC
GHKLKDLTLPPETLIVLIRRGEQNIIPDGETIILQNDVLVLSAITPDEVHGIKLVEKIIE
CCCCCCCCCCHHHHEEEEECCCCCCCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHH
KDSRYNNKLLSEISKKHNEIIIMIQRNGQVIIPNGNVRLTTGDILVINRAVN
HCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA