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The map label for this gene is ttcA [H]

Identifier: 238922390

GI number: 238922390

Start: 594231

End: 594959

Strand: Reverse

Name: ttcA [H]

Synonym: EUBELI_20626

Alternate gene names: 238922390

Gene position: 594959-594231 (Counterclockwise)

Preceding gene: 238922391

Following gene: 238922389

Centisome position: 94.93

GC content: 40.33

Gene sequence:

>729_bases
ATGCAACAACAGAAATTATTAAGCCTTATAAGACAGGCAATAGAAGATTACAACATGATAGAGGAAGGCGATAAGATTGC
CGTTGGAGTATCAGGTGGCAAGGATTCGCTTGCGTTGCTGCATGCAATGAAGATACTTAACAGATTTTATCCGAAGAAGT
TTGAACTGTATGCAATTACCTGTAATGTTGGATTTGAGGGAATGGATTTTACAGGAGTGAGGAAGTTCTGTGAGAGTATA
AATGTGCCATATGAACAGGTTGATACAGAGATTGCGAAGATTGTCTTTGAGGATAATAAAGACGAAAGACCATGTTCACT
GTGTGCGAAGCTTAGAAAAGGCGCAATGTATAAGAGGCTTGGAGAGCTTGGAATCAATAAGATTGCATATGCACATAATA
AGGACGATTTTATAGAAACAGCATTAATGTCTCTTATATATGAAGGGCGGTTTTACGCATTTCCACCAGTTACATATCTG
CCAGAGGCAGGGGTTACGGTTATACGGCCAATGATGTATGCACCGGAAAAGGGTGTGGCTAATTTTGTGATTAATCAGGG
AATCAAGGTTGTTAAGAACACCTGTCCGGTTGATGGTTCAACTAAGAGGGAATATGCCAAGCAGCTTATGGAGCAGATTA
ATAGAGAAAATCCGGGAACTAAGGACAGAATTATGCATGCAGTTGTGAACGGAAGATTTGAGGACTGGCCAGAAGTGCAT
AGAAATTGA

Upstream 100 bases:

>100_bases
CAATTTAATATATGATAGTGTAACCGGGGGAGGGAGAATGGATTTTAGTTGATACTGAAGATGAGATGGTGGCTATTTTT
TACAACAGAGGATATATTTT

Downstream 100 bases:

>100_bases
AAATAACTGTTGATACAACACCAATGAGATAATAGAATAATATTAAATCTATTTATAAGGAGATACGAACATGAGAAGAT
TTTATGAAGGCAATGATAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MQQQKLLSLIRQAIEDYNMIEEGDKIAVGVSGGKDSLALLHAMKILNRFYPKKFELYAITCNVGFEGMDFTGVRKFCESI
NVPYEQVDTEIAKIVFEDNKDERPCSLCAKLRKGAMYKRLGELGINKIAYAHNKDDFIETALMSLIYEGRFYAFPPVTYL
PEAGVTVIRPMMYAPEKGVANFVINQGIKVVKNTCPVDGSTKREYAKQLMEQINRENPGTKDRIMHAVVNGRFEDWPEVH
RN

Sequences:

>Translated_242_residues
MQQQKLLSLIRQAIEDYNMIEEGDKIAVGVSGGKDSLALLHAMKILNRFYPKKFELYAITCNVGFEGMDFTGVRKFCESI
NVPYEQVDTEIAKIVFEDNKDERPCSLCAKLRKGAMYKRLGELGINKIAYAHNKDDFIETALMSLIYEGRFYAFPPVTYL
PEAGVTVIRPMMYAPEKGVANFVINQGIKVVKNTCPVDGSTKREYAKQLMEQINRENPGTKDRIMHAVVNGRFEDWPEVH
RN
>Mature_242_residues
MQQQKLLSLIRQAIEDYNMIEEGDKIAVGVSGGKDSLALLHAMKILNRFYPKKFELYAITCNVGFEGMDFTGVRKFCESI
NVPYEQVDTEIAKIVFEDNKDERPCSLCAKLRKGAMYKRLGELGINKIAYAHNKDDFIETALMSLIYEGRFYAFPPVTYL
PEAGVTVIRPMMYAPEKGVANFVINQGIKVVKNTCPVDGSTKREYAKQLMEQINRENPGTKDRIMHAVVNGRFEDWPEVH
RN

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=230, Percent_Identity=30.8695652173913, Blast_Score=127, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI193211090, Length=205, Percent_Identity=27.8048780487805, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24651972, Length=243, Percent_Identity=25.1028806584362, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 27572; Mature: 27572

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQKLLSLIRQAIEDYNMIEEGDKIAVGVSGGKDSLALLHAMKILNRFYPKKFELYAIT
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
CNVGFEGMDFTGVRKFCESINVPYEQVDTEIAKIVFEDNKDERPCSLCAKLRKGAMYKRL
EECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
GELGINKIAYAHNKDDFIETALMSLIYEGRFYAFPPVTYLPEAGVTVIRPMMYAPEKGVA
HHHCHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHCCCCHHH
NFVINQGIKVVKNTCPVDGSTKREYAKQLMEQINRENPGTKDRIMHAVVNGRFEDWPEVH
HHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHC
RN
CC
>Mature Secondary Structure
MQQQKLLSLIRQAIEDYNMIEEGDKIAVGVSGGKDSLALLHAMKILNRFYPKKFELYAIT
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
CNVGFEGMDFTGVRKFCESINVPYEQVDTEIAKIVFEDNKDERPCSLCAKLRKGAMYKRL
EECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
GELGINKIAYAHNKDDFIETALMSLIYEGRFYAFPPVTYLPEAGVTVIRPMMYAPEKGVA
HHHCHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHCCCCHHH
NFVINQGIKVVKNTCPVDGSTKREYAKQLMEQINRENPGTKDRIMHAVVNGRFEDWPEVH
HHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHC
RN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA