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The map label for this gene is uxuA [H]

Identifier: 238922359

GI number: 238922359

Start: 568858

End: 569979

Strand: Reverse

Name: uxuA [H]

Synonym: EUBELI_20595

Alternate gene names: 238922359

Gene position: 569979-568858 (Counterclockwise)

Preceding gene: 238922360

Following gene: 238922358

Centisome position: 90.94

GC content: 38.32

Gene sequence:

>1122_bases
ATGCAAATATGGTACAGAATAATAATGTTGTTATGTAAAAGGAGGATTTTTGTTATGGATATGACATTGAGATGGTATGG
ACCAGGATACGACAGCGTAACACTTAAGCAGATCAGACAGATTCCAGGCGTAAAGAATGTTATTACAACGCTTTTTGGTA
AGCAGGCTGGGGAGCGGTGGCTTCCAGAGGAAATAGCGGAGCTTAAAAGGATTGTTGAAGATGCCGGGTTGGGAATCGCT
GGTATTGAATCTGTTAATGTGTCAGATGATATTAAGATTGGCACAGCTAAGGCAGATGAGCACATTGACAATTATATAAA
GACTTTGCAGGCTCTTGGAGAAGCGGATATTCATGTGGTATGTTACAATTTTATGCCTGTATTTGACTGGACACGATCAG
AACTTGCAAGAGAAAGAGCTGATGGTTCAACGGTGCTTGCATATAATCAGGATACAGTTGATATGATTGATCCGGAGCAT
ATGAAGGAATCAGTTGCAAAGATGTCTAATGGATTCGTAATGCCAGGATGGGAACCAGAGCGTCTTGACAGATTAAAAGA
ACTTTTTGAAATGTATAAAGATGTTGACGCAGAGAAACTGTTTAATAATCTGGTATATTTTCTGGAAGCAATTGGTCCGG
TATGTGAGAAGTATGATATAAAGATGGGTATTCATCCGGATGATCCTGCGTGGCCTATATTTGGACTTCCAAGAATTATG
ACAGGTAAGGATTCTGTTACAAAACTTCTTGATGCTGTAAATAAACCATATAACGGAATAACACTTTGTACGGGTTCATT
TGGCTCTAACCAGAATAATGATATTTGTGAGATTATCAAGGCGTGCAGAGGAAGAATACCATTTGCACATGTGAGAAACC
TTAAATATAATTCACCTAGGGATTTTGAAGAAGCAGCACATTTATCATCTGATGGTTCTATGGATATGTATAAGATTATG
AAAACATTATATGATACAGGTTTTGACGGCATTATAAGACCTGACCATGGAAGAATGATATGGGATGAGGTGGCTATGCC
AGGTTATGGTTTATATGACAGGGCTTTAGGTGCAACATACCTTAATGGCTTATGGGAAGCTATTGATAAATCATCAAAGT
AA

Upstream 100 bases:

>100_bases
GAAAAGATATCAAAATAAATTGAAAAACATAACAAAATAAACTCAAAAAATACATTGACATGTTAGAACTGACATGTTAG
TATACACATAGCAAATAATT

Downstream 100 bases:

>100_bases
TTATTAACATTGGGTTTTTATGACATAATGGAGGATATTATGAAACTTTCAATAAATGGTATTAAGAATACGACAGATTG
GGAAAAGGCTGGCATAAAGC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MQIWYRIIMLLCKRRIFVMDMTLRWYGPGYDSVTLKQIRQIPGVKNVITTLFGKQAGERWLPEEIAELKRIVEDAGLGIA
GIESVNVSDDIKIGTAKADEHIDNYIKTLQALGEADIHVVCYNFMPVFDWTRSELARERADGSTVLAYNQDTVDMIDPEH
MKESVAKMSNGFVMPGWEPERLDRLKELFEMYKDVDAEKLFNNLVYFLEAIGPVCEKYDIKMGIHPDDPAWPIFGLPRIM
TGKDSVTKLLDAVNKPYNGITLCTGSFGSNQNNDICEIIKACRGRIPFAHVRNLKYNSPRDFEEAAHLSSDGSMDMYKIM
KTLYDTGFDGIIRPDHGRMIWDEVAMPGYGLYDRALGATYLNGLWEAIDKSSK

Sequences:

>Translated_373_residues
MQIWYRIIMLLCKRRIFVMDMTLRWYGPGYDSVTLKQIRQIPGVKNVITTLFGKQAGERWLPEEIAELKRIVEDAGLGIA
GIESVNVSDDIKIGTAKADEHIDNYIKTLQALGEADIHVVCYNFMPVFDWTRSELARERADGSTVLAYNQDTVDMIDPEH
MKESVAKMSNGFVMPGWEPERLDRLKELFEMYKDVDAEKLFNNLVYFLEAIGPVCEKYDIKMGIHPDDPAWPIFGLPRIM
TGKDSVTKLLDAVNKPYNGITLCTGSFGSNQNNDICEIIKACRGRIPFAHVRNLKYNSPRDFEEAAHLSSDGSMDMYKIM
KTLYDTGFDGIIRPDHGRMIWDEVAMPGYGLYDRALGATYLNGLWEAIDKSSK
>Mature_373_residues
MQIWYRIIMLLCKRRIFVMDMTLRWYGPGYDSVTLKQIRQIPGVKNVITTLFGKQAGERWLPEEIAELKRIVEDAGLGIA
GIESVNVSDDIKIGTAKADEHIDNYIKTLQALGEADIHVVCYNFMPVFDWTRSELARERADGSTVLAYNQDTVDMIDPEH
MKESVAKMSNGFVMPGWEPERLDRLKELFEMYKDVDAEKLFNNLVYFLEAIGPVCEKYDIKMGIHPDDPAWPIFGLPRIM
TGKDSVTKLLDAVNKPYNGITLCTGSFGSNQNNDICEIIKACRGRIPFAHVRNLKYNSPRDFEEAAHLSSDGSMDMYKIM
KTLYDTGFDGIIRPDHGRMIWDEVAMPGYGLYDRALGATYLNGLWEAIDKSSK

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=394, Percent_Identity=36.8020304568528, Blast_Score=242, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 42437; Mature: 42437

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIWYRIIMLLCKRRIFVMDMTLRWYGPGYDSVTLKQIRQIPGVKNVITTLFGKQAGERW
CHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LPEEIAELKRIVEDAGLGIAGIESVNVSDDIKIGTAKADEHIDNYIKTLQALGEADIHVV
CHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCEEEE
CYNFMPVFDWTRSELARERADGSTVLAYNQDTVDMIDPEHMKESVAKMSNGFVMPGWEPE
EEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCEECCCCCHH
RLDRLKELFEMYKDVDAEKLFNNLVYFLEAIGPVCEKYDIKMGIHPDDPAWPIFGLPRIM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCC
TGKDSVTKLLDAVNKPYNGITLCTGSFGSNQNNDICEIIKACRGRIPFAHVRNLKYNSPR
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCC
DFEEAAHLSSDGSMDMYKIMKTLYDTGFDGIIRPDHGRMIWDEVAMPGYGLYDRALGATY
CHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEHHHHCCCCCCHHHHHHHHHH
LNGLWEAIDKSSK
HHHHHHHHHCCCC
>Mature Secondary Structure
MQIWYRIIMLLCKRRIFVMDMTLRWYGPGYDSVTLKQIRQIPGVKNVITTLFGKQAGERW
CHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LPEEIAELKRIVEDAGLGIAGIESVNVSDDIKIGTAKADEHIDNYIKTLQALGEADIHVV
CHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCEEEE
CYNFMPVFDWTRSELARERADGSTVLAYNQDTVDMIDPEHMKESVAKMSNGFVMPGWEPE
EEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCEECCCCCHH
RLDRLKELFEMYKDVDAEKLFNNLVYFLEAIGPVCEKYDIKMGIHPDDPAWPIFGLPRIM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCC
TGKDSVTKLLDAVNKPYNGITLCTGSFGSNQNNDICEIIKACRGRIPFAHVRNLKYNSPR
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCC
DFEEAAHLSSDGSMDMYKIMKTLYDTGFDGIIRPDHGRMIWDEVAMPGYGLYDRALGATY
CHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEHHHHCCCCCCHHHHHHHHHH
LNGLWEAIDKSSK
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA