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The map label for this gene is yeiQ [H]

Identifier: 238922358

GI number: 238922358

Start: 567211

End: 568830

Strand: Reverse

Name: yeiQ [H]

Synonym: EUBELI_20594

Alternate gene names: 238922358

Gene position: 568830-567211 (Counterclockwise)

Preceding gene: 238922359

Following gene: 238922357

Centisome position: 90.76

GC content: 36.36

Gene sequence:

>1620_bases
ATGGAGGATATTATGAAACTTTCAATAAATGGTATTAAGAATACGACAGATTGGGAAAAGGCTGGCATAAAGCTGCCTTC
ATATGATGTTGAAAAGGTTGCAGAGGATACAAAAAAGTCACCTGTATGGGTACATTTTGGTATTGGCAATATTTTCAGGA
TATTCATTGGTGGAATTGCAGATTCATTATTAGAACAAGGAGTTTCAGATAAAGGCATTACATGTGTTGAAACATTTGAC
TTCGATGTAGTAGATAAAATATATAAGCCATTTGATAATCTTGTTATGGCTGTTACATTGAAGGAGGATGGAAATACAGA
AAAAAAGGTACTTGGTTCACTTACAGAAGCTATTAAGGCACAATCATATTCGCAGAAGGAATGGGAAAGATTAAAGGAGA
TATTTGCTGACCCTGGGCTTCAGATGGTGTCATTTACTATTACAGAAAAAGGTTATGCGTTGAAGGATTCTAAAGGAGAG
TTTTTTTCTTTTATCAGGGAAGACATTGATAATGGACCAGAAAAAGCAACATCAGCAATGGCAGTAACAGCAGCACTTTT
GTATGAACGTTTTAAAGCCTGTAAGGCACCGATTGCAGTTGTATCAATGGATAACTGCTCACATAACGGAGAGAAACTTA
GAAATTCGATAACCGAGATGGTAAGTGAGTGGAATAAAAAAGGATTTGTTGGTAATGATTTTGTTGATTATGTGAATAAT
GAAGAGCTTGTATCATTTCCATGGTCTATGATTGATAAAATTACACCAAGACCAGCAGATAGTGTTGCTAAAGCATTAGA
GGAAGCAGGTGTTGAGGATATGAGTCCGGTGATAACATCTAAGAAGACATATATTGCACCATTTGTAAATGCTGAAGGAC
CACAGTATCTTGTAATAGAAGACAGGTTCCCTAATGGCAGACCTCAGCTTGAAAAAGCAGGTGTGTTTATGACTGATAGA
CAGACAGTTAATAAGGTTGAGCGTATGAAAGTAACAACCTGCCTTAATCCGTTACACACAGCCTTAGCAGTATATGGCTG
CTTATTAGGATATAATCTGATTGCTGATGAAATGAAAGACAAGGAACTTTCAGAGCTTGTGAGACGAATTGGGTTATCTG
AGGGAATGCCTGTGGTAATTAATCCGGAGATAATTTCACCACAGAAGTTTGTGGATGAAGTTCTTAATGTAAGAATACCT
AATCCTTTTATGCCTGATACACCGCAAAGAATAGCGACAGATACTTCACAGAAGGTAGGAATACGGTATGGTGAAACAAT
TAAGTCATATGTTGCAAAGGACGGAAGTGCCAAAGAATTAATAGCGATTCCATTGGCAATTGCAGGATGGTGCAGATATC
TTCTTGGAATTGATGATAATGGCGAAAGCTTCGAATTGTCTCCAGATCCGATGGCAGATGAATTAAAGAAGCATTTATCA
GGTATAAAAATAGGTGACATATCATCTTATACAGGACAGCTTAAGAATTTATTGTCAAATGCTAATATATTTGGTATAAA
TTTATATGAAGCAGGAATTGGCGATAAAATAGAAGAGATGTTTGTTGAAGAGATAGCAGGAAAGGGTGCTATAAGAAATA
CACTTAAAAAATACCTTTAA

Upstream 100 bases:

>100_bases
TTTATATGACAGGGCTTTAGGTGCAACATACCTTAATGGCTTATGGGAAGCTATTGATAAATCATCAAAGTAATTATTAA
CATTGGGTTTTTATGACATA

Downstream 100 bases:

>100_bases
TATATATAACAAGCAGGCTCATAGTATAAGAAAGGCCGCAGGGTTATGGAAAAATCATTAAACGAAGACACATACGAAAA
ATTAAAATACGATATCATGA

Product: fructuronate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MEDIMKLSINGIKNTTDWEKAGIKLPSYDVEKVAEDTKKSPVWVHFGIGNIFRIFIGGIADSLLEQGVSDKGITCVETFD
FDVVDKIYKPFDNLVMAVTLKEDGNTEKKVLGSLTEAIKAQSYSQKEWERLKEIFADPGLQMVSFTITEKGYALKDSKGE
FFSFIREDIDNGPEKATSAMAVTAALLYERFKACKAPIAVVSMDNCSHNGEKLRNSITEMVSEWNKKGFVGNDFVDYVNN
EELVSFPWSMIDKITPRPADSVAKALEEAGVEDMSPVITSKKTYIAPFVNAEGPQYLVIEDRFPNGRPQLEKAGVFMTDR
QTVNKVERMKVTTCLNPLHTALAVYGCLLGYNLIADEMKDKELSELVRRIGLSEGMPVVINPEIISPQKFVDEVLNVRIP
NPFMPDTPQRIATDTSQKVGIRYGETIKSYVAKDGSAKELIAIPLAIAGWCRYLLGIDDNGESFELSPDPMADELKKHLS
GIKIGDISSYTGQLKNLLSNANIFGINLYEAGIGDKIEEMFVEEIAGKGAIRNTLKKYL

Sequences:

>Translated_539_residues
MEDIMKLSINGIKNTTDWEKAGIKLPSYDVEKVAEDTKKSPVWVHFGIGNIFRIFIGGIADSLLEQGVSDKGITCVETFD
FDVVDKIYKPFDNLVMAVTLKEDGNTEKKVLGSLTEAIKAQSYSQKEWERLKEIFADPGLQMVSFTITEKGYALKDSKGE
FFSFIREDIDNGPEKATSAMAVTAALLYERFKACKAPIAVVSMDNCSHNGEKLRNSITEMVSEWNKKGFVGNDFVDYVNN
EELVSFPWSMIDKITPRPADSVAKALEEAGVEDMSPVITSKKTYIAPFVNAEGPQYLVIEDRFPNGRPQLEKAGVFMTDR
QTVNKVERMKVTTCLNPLHTALAVYGCLLGYNLIADEMKDKELSELVRRIGLSEGMPVVINPEIISPQKFVDEVLNVRIP
NPFMPDTPQRIATDTSQKVGIRYGETIKSYVAKDGSAKELIAIPLAIAGWCRYLLGIDDNGESFELSPDPMADELKKHLS
GIKIGDISSYTGQLKNLLSNANIFGINLYEAGIGDKIEEMFVEEIAGKGAIRNTLKKYL
>Mature_539_residues
MEDIMKLSINGIKNTTDWEKAGIKLPSYDVEKVAEDTKKSPVWVHFGIGNIFRIFIGGIADSLLEQGVSDKGITCVETFD
FDVVDKIYKPFDNLVMAVTLKEDGNTEKKVLGSLTEAIKAQSYSQKEWERLKEIFADPGLQMVSFTITEKGYALKDSKGE
FFSFIREDIDNGPEKATSAMAVTAALLYERFKACKAPIAVVSMDNCSHNGEKLRNSITEMVSEWNKKGFVGNDFVDYVNN
EELVSFPWSMIDKITPRPADSVAKALEEAGVEDMSPVITSKKTYIAPFVNAEGPQYLVIEDRFPNGRPQLEKAGVFMTDR
QTVNKVERMKVTTCLNPLHTALAVYGCLLGYNLIADEMKDKELSELVRRIGLSEGMPVVINPEIISPQKFVDEVLNVRIP
NPFMPDTPQRIATDTSQKVGIRYGETIKSYVAKDGSAKELIAIPLAIAGWCRYLLGIDDNGESFELSPDPMADELKKHLS
GIKIGDISSYTGQLKNLLSNANIFGINLYEAGIGDKIEEMFVEEIAGKGAIRNTLKKYL

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=526, Percent_Identity=28.3269961977186, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787823, Length=523, Percent_Identity=28.8718929254302, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1790779, Length=495, Percent_Identity=28.2828282828283, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI48994885, Length=440, Percent_Identity=22.9545454545455, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324401, Length=464, Percent_Identity=28.2327586206897, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320765, Length=464, Percent_Identity=28.2327586206897, Blast_Score=141, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 59890; Mature: 59890

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIMKLSINGIKNTTDWEKAGIKLPSYDVEKVAEDTKKSPVWVHFGIGNIFRIFIGGIA
CCCCCEEECCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
DSLLEQGVSDKGITCVETFDFDVVDKIYKPFDNLVMAVTLKEDGNTEKKVLGSLTEAIKA
HHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
QSYSQKEWERLKEIFADPGLQMVSFTITEKGYALKDSKGEFFSFIREDIDNGPEKATSAM
CCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEECCCHHHHHHHHHHHCCCHHHHHHHH
AVTAALLYERFKACKAPIAVVSMDNCSHNGEKLRNSITEMVSEWNKKGFVGNDFVDYVNN
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
EELVSFPWSMIDKITPRPADSVAKALEEAGVEDMSPVITSKKTYIAPFVNAEGPQYLVIE
CCCEECCHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCCEEEEEE
DRFPNGRPQLEKAGVFMTDRQTVNKVERMKVTTCLNPLHTALAVYGCLLGYNLIADEMKD
CCCCCCCCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
KELSELVRRIGLSEGMPVVINPEIISPQKFVDEVLNVRIPNPFMPDTPQRIATDTSQKVG
HHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHCC
IRYGETIKSYVAKDGSAKELIAIPLAIAGWCRYLLGIDDNGESFELSPDPMADELKKHLS
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHC
GIKIGDISSYTGQLKNLLSNANIFGINLYEAGIGDKIEEMFVEEIAGKGAIRNTLKKYL
CCEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHC
>Mature Secondary Structure
MEDIMKLSINGIKNTTDWEKAGIKLPSYDVEKVAEDTKKSPVWVHFGIGNIFRIFIGGIA
CCCCCEEECCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
DSLLEQGVSDKGITCVETFDFDVVDKIYKPFDNLVMAVTLKEDGNTEKKVLGSLTEAIKA
HHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
QSYSQKEWERLKEIFADPGLQMVSFTITEKGYALKDSKGEFFSFIREDIDNGPEKATSAM
CCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEECCCHHHHHHHHHHHCCCHHHHHHHH
AVTAALLYERFKACKAPIAVVSMDNCSHNGEKLRNSITEMVSEWNKKGFVGNDFVDYVNN
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
EELVSFPWSMIDKITPRPADSVAKALEEAGVEDMSPVITSKKTYIAPFVNAEGPQYLVIE
CCCEECCHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCCEEEEEE
DRFPNGRPQLEKAGVFMTDRQTVNKVERMKVTTCLNPLHTALAVYGCLLGYNLIADEMKD
CCCCCCCCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
KELSELVRRIGLSEGMPVVINPEIISPQKFVDEVLNVRIPNPFMPDTPQRIATDTSQKVG
HHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHCC
IRYGETIKSYVAKDGSAKELIAIPLAIAGWCRYLLGIDDNGESFELSPDPMADELKKHLS
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHC
GIKIGDISSYTGQLKNLLSNANIFGINLYEAGIGDKIEEMFVEEIAGKGAIRNTLKKYL
CCEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]