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The map label for this gene is yycF [H]

Identifier: 238922349

GI number: 238922349

Start: 555926

End: 556597

Strand: Reverse

Name: yycF [H]

Synonym: EUBELI_20585

Alternate gene names: 238922349

Gene position: 556597-555926 (Counterclockwise)

Preceding gene: 238922350

Following gene: 238922348

Centisome position: 88.81

GC content: 37.2

Gene sequence:

>672_bases
ATGATAGCTGTTGTTGAAGATGAGAAGGAATTATGTGAAAGCCTTAAGCTTTTATTGATTGATAAGGGGTATGAGATAGT
TACTGCCGGAAGCTGCGGTGAGGCAGATAAATTTATTGGCAATCCGCAGATAGATATGTTTCTGTTGGATGTCAAACTGC
CTGATGGAAGCGGGTTTGATATATGCAGGAAGATAAGAAAATCAAGCGAAGTGCCGGTTATATTCTTAACCTCATGTGAT
AATGAGGAAGAGATAGTTACAGGGCTTGATATAGGTGCAGATGATTATATAACAAAGCCGTTTTATACGAAGGAGCTGCT
TTCAAGAATAAGTGCCAACTTAAGAAGAAGCAAGTTCAATGCAGGATATATCTATAAGAAAGGTGATATTGTCGTTGATT
TTGACAGATATAAGATAAGCCGTCAGGGTGATGAACTAAATATATCGACTAATGAATTCGATATTGTAAAAATGCTTATA
GAGAATAAAGGCAGAGTCGTAAGGCGTGATGCTATATATGAGAAAATATGGGATATTCACGGTAATTTCGTTGAATATAA
CACACTTACCGTTGCGATGAGCAGAATAAAAGCAAAGCTTGGAACATATGGTGAGAAGCATCAGCAATACATTGAGACTA
TAAGAAATGTGGGCTACAGGTGGATTGACTAA

Upstream 100 bases:

>100_bases
TTCTGCTTGTGCCATACATAAAGCATTATTATCTGCTTGAAAACGAGGTGCAGAAAATGTATAAGCAGTATGACAGGATA
TGTGAAAAGGAACGGAAATT

Downstream 100 bases:

>100_bases
TAACTTTCAGGGGGATTTATGGATAATATGGTCAAGAAGAAACTGTCTGCATTCAGGAAAAGACAGACTGTTTTCGTTAT
TATATATGGATTGATTAATG

Product: two-component system, OmpR family, response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MIAVVEDEKELCESLKLLLIDKGYEIVTAGSCGEADKFIGNPQIDMFLLDVKLPDGSGFDICRKIRKSSEVPVIFLTSCD
NEEEIVTGLDIGADDYITKPFYTKELLSRISANLRRSKFNAGYIYKKGDIVVDFDRYKISRQGDELNISTNEFDIVKMLI
ENKGRVVRRDAIYEKIWDIHGNFVEYNTLTVAMSRIKAKLGTYGEKHQQYIETIRNVGYRWID

Sequences:

>Translated_223_residues
MIAVVEDEKELCESLKLLLIDKGYEIVTAGSCGEADKFIGNPQIDMFLLDVKLPDGSGFDICRKIRKSSEVPVIFLTSCD
NEEEIVTGLDIGADDYITKPFYTKELLSRISANLRRSKFNAGYIYKKGDIVVDFDRYKISRQGDELNISTNEFDIVKMLI
ENKGRVVRRDAIYEKIWDIHGNFVEYNTLTVAMSRIKAKLGTYGEKHQQYIETIRNVGYRWID
>Mature_223_residues
MIAVVEDEKELCESLKLLLIDKGYEIVTAGSCGEADKFIGNPQIDMFLLDVKLPDGSGFDICRKIRKSSEVPVIFLTSCD
NEEEIVTGLDIGADDYITKPFYTKELLSRISANLRRSKFNAGYIYKKGDIVVDFDRYKISRQGDELNISTNEFDIVKMLI
ENKGRVVRRDAIYEKIWDIHGNFVEYNTLTVAMSRIKAKLGTYGEKHQQYIETIRNVGYRWID

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=32.5892857142857, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=32.1428571428571, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=30.1369863013699, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=27.9475982532751, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=29.2792792792793, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=29.9107142857143, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=30.8035714285714, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=31.390134529148, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=31.6964285714286, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=30.8370044052863, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=30.9417040358744, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=29.7413793103448, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1787229, Length=208, Percent_Identity=25, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=25.1082251082251, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25589; Mature: 25589

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVVEDEKELCESLKLLLIDKGYEIVTAGSCGEADKFIGNPQIDMFLLDVKLPDGSGFD
CEEEECCHHHHHHHHEEEEEECCCEEEECCCCCCHHHHCCCCCEEEEEEEEECCCCCCHH
ICRKIRKSSEVPVIFLTSCDNEEEIVTGLDIGADDYITKPFYTKELLSRISANLRRSKFN
HHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
AGYIYKKGDIVVDFDRYKISRQGDELNISTNEFDIVKMLIENKGRVVRRDAIYEKIWDIH
CCEEEECCCEEEEEHHEEEECCCCEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHC
GNFVEYNTLTVAMSRIKAKLGTYGEKHQQYIETIRNVGYRWID
CCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MIAVVEDEKELCESLKLLLIDKGYEIVTAGSCGEADKFIGNPQIDMFLLDVKLPDGSGFD
CEEEECCHHHHHHHHEEEEEECCCEEEECCCCCCHHHHCCCCCEEEEEEEEECCCCCCHH
ICRKIRKSSEVPVIFLTSCDNEEEIVTGLDIGADDYITKPFYTKELLSRISANLRRSKFN
HHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
AGYIYKKGDIVVDFDRYKISRQGDELNISTNEFDIVKMLIENKGRVVRRDAIYEKIWDIH
CCEEEECCCEEEEEHHEEEECCCCEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHC
GNFVEYNTLTVAMSRIKAKLGTYGEKHQQYIETIRNVGYRWID
CCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]