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The map label for this gene is aroB

Identifier: 238921471

GI number: 238921471

Start: 3509697

End: 3510782

Strand: Reverse

Name: aroB

Synonym: NT01EI_3623

Alternate gene names: 238921471

Gene position: 3510782-3509697 (Counterclockwise)

Preceding gene: 238921472

Following gene: 238921470

Centisome position: 92.09

GC content: 64.18

Gene sequence:

>1086_bases
GTGGAAAGGATAACCGTAACGCTCGGGGAGCGCAGCTACCCGATCAGCATCGCCAGTGGGCTTTTTTCACAGGAGGCGGC
TTTCTGGCCGCTGCGCTCCGGCGAGCAGGCCATGCTGGTCACCAACGAAACCCTGGCCAAACTGTATCTGGCGCCGGTTC
AGCGCACGCTGGAGCGGGCAGGCGTACGCGTCGGGCAGGTGATCCTGCCCGACGGTGAGCAGTTTAAGTCACTGAGCGTA
CTGGAGCGGGTATTCAGCGCGCTGCTGGAGAACAACCACGGGCGGGATACCACGCTGGTGGCGTTGGGGGGCGGCGTGAT
CGGCGATCTGATCGGTTTTGCCGCCGCGTGCTATCAGCGCGGTGTGCGCTTCATTCAGGTGCCGACAACGCTGTTGGCGC
AGGTGGACTCCTCGGTGGGCGGGAAGACTGCGGTCAATCATCCGCTGGGTAAGAATATGATCGGCGCGTTTTATCAGCCG
GCCAGCGTGACGATCGACATCGACTGTCTGCAGACCCTGCCACTGCGCGAGCTCGCCTCCGGGCTGGCGGAGGTCATTAA
ATACGGCATCATCATGGATGCCGATTTTTTCCGTTGGCTTGAGACGCAGATGGATGCGCTGCTGCGTCTGGAGCCGTCCG
CGCTGGTCTACTGTATCCGCCGCTGCTGCGAGCTGAAGGCGCAGGTGGTGGCGGAGGATGAGCGTGAGCAGGGCCGCCGG
GCGCTGTTGAATCTCGGCCATACGTTTGGTCATGCCATCGAGGCTGAGATGGGCTATGGCAACTGGCTGCACGGCGAGGC
AGTGGCCGCGGGGACGATGATGGCGGCCCGCGTGGCCTGCCGTCTGGGCTATCTGCAGCCGCAGCAGGCCGAGCGTATGT
CGGCGCTACTGACGCGCGCCGGGCTGCCGGTGCAGGGGCCGGCTGGTATGATCCCTGACGCCTATCTGCCGCATATGCTG
CGTGATAAGAAGGTGCTGGGCGGAACCCTGCGGCTGGTGTTGCCGACCGCTATCGGTAGCGCGGAGGTGTTCGCAGGGGT
AAGCCATGATGTCGTGCGGGACGCGATTGCGGACTGCCTGGCCTGA

Upstream 100 bases:

>100_bases
CAGAGCGCCAAAGTGGTGGCCAACCAGATTATCCATTTGCTGGAAAACAACTGAACGGTTGGCTGAGGAACTAGCGTTGT
AACAGGGGGGCTGGCAGGCC

Downstream 100 bases:

>100_bases
GCGGTTAATTGGCGAGTCTCCGGCGCGGTACGGTCGGCTTTGCCCCTAAGTGGAGGGTGAGATGGATCAAGAAGAGTTTA
AAGCAGATGATGAGTTAAAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MERITVTLGERSYPISIASGLFSQEAAFWPLRSGEQAMLVTNETLAKLYLAPVQRTLERAGVRVGQVILPDGEQFKSLSV
LERVFSALLENNHGRDTTLVALGGGVIGDLIGFAAACYQRGVRFIQVPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVTIDIDCLQTLPLRELASGLAEVIKYGIIMDADFFRWLETQMDALLRLEPSALVYCIRRCCELKAQVVAEDEREQGRR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTMMAARVACRLGYLQPQQAERMSALLTRAGLPVQGPAGMIPDAYLPHML
RDKKVLGGTLRLVLPTAIGSAEVFAGVSHDVVRDAIADCLA

Sequences:

>Translated_361_residues
MERITVTLGERSYPISIASGLFSQEAAFWPLRSGEQAMLVTNETLAKLYLAPVQRTLERAGVRVGQVILPDGEQFKSLSV
LERVFSALLENNHGRDTTLVALGGGVIGDLIGFAAACYQRGVRFIQVPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVTIDIDCLQTLPLRELASGLAEVIKYGIIMDADFFRWLETQMDALLRLEPSALVYCIRRCCELKAQVVAEDEREQGRR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTMMAARVACRLGYLQPQQAERMSALLTRAGLPVQGPAGMIPDAYLPHML
RDKKVLGGTLRLVLPTAIGSAEVFAGVSHDVVRDAIADCLA
>Mature_361_residues
MERITVTLGERSYPISIASGLFSQEAAFWPLRSGEQAMLVTNETLAKLYLAPVQRTLERAGVRVGQVILPDGEQFKSLSV
LERVFSALLENNHGRDTTLVALGGGVIGDLIGFAAACYQRGVRFIQVPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVTIDIDCLQTLPLRELASGLAEVIKYGIIMDADFFRWLETQMDALLRLEPSALVYCIRRCCELKAQVVAEDEREQGRR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTMMAARVACRLGYLQPQQAERMSALLTRAGLPVQGPAGMIPDAYLPHML
RDKKVLGGTLRLVLPTAIGSAEVFAGVSHDVVRDAIADCLA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=359, Percent_Identity=75.4874651810585, Blast_Score=540, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6320332, Length=316, Percent_Identity=39.2405063291139, Blast_Score=200, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_EDWI9 (C5BGQ4)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934986.1
- GeneID:   7961444
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3623
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39047; Mature: 39047

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERITVTLGERSYPISIASGLFSQEAAFWPLRSGEQAMLVTNETLAKLYLAPVQRTLERA
CCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHC
GVRVGQVILPDGEQFKSLSVLERVFSALLENNHGRDTTLVALGGGVIGDLIGFAAACYQR
CCEECEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHC
GVRFIQVPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPASVTIDIDCLQTLPLRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHCCCHHHHHH
GLAEVIKYGIIMDADFFRWLETQMDALLRLEPSALVYCIRRCCELKAQVVAEDEREQGRR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTMMAARVACRLGYLQPQQAERMSALLTRA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GLPVQGPAGMIPDAYLPHMLRDKKVLGGTLRLVLPTAIGSAEVFAGVSHDVVRDAIADCL
CCCCCCCCCCCCCHHHHHHHHCCHHHCCCEEEEEHHHCCCHHHHHCCHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MERITVTLGERSYPISIASGLFSQEAAFWPLRSGEQAMLVTNETLAKLYLAPVQRTLERA
CCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHC
GVRVGQVILPDGEQFKSLSVLERVFSALLENNHGRDTTLVALGGGVIGDLIGFAAACYQR
CCEECEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHC
GVRFIQVPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPASVTIDIDCLQTLPLRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHCCCHHHHHH
GLAEVIKYGIIMDADFFRWLETQMDALLRLEPSALVYCIRRCCELKAQVVAEDEREQGRR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTMMAARVACRLGYLQPQQAERMSALLTRA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GLPVQGPAGMIPDAYLPHMLRDKKVLGGTLRLVLPTAIGSAEVFAGVSHDVVRDAIADCL
CCCCCCCCCCCCCHHHHHHHHCCHHHCCCEEEEEHHHCCCHHHHHCCHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA