Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 238921466

GI number: 238921466

Start: 3505280

End: 3506284

Strand: Reverse

Name: trpS [H]

Synonym: NT01EI_3618

Alternate gene names: 238921466

Gene position: 3506284-3505280 (Counterclockwise)

Preceding gene: 238921467

Following gene: 238921464

Centisome position: 91.97

GC content: 57.61

Gene sequence:

>1005_bases
ATGAGTAAGCCCATTGTTTTCAGCGGTGCGCAGCCGTCTGGTGAACTCACCATCGGTAACTATATGGGCGCGCTGCGCCA
GTGGGTACAGATGCAGGATGAGTATGACTGCATTTACTGTATCGTCGATCAGCACGCCATCACCGTGCGTCAGGACGCAG
AGAAACTGCGCAGCGCGACGCTGGATACGCTGGCCCTGTACCTAGCCTGCGGTATCGATCCGCAGAAGAGCACGATTTTT
GTGCAGTCTCATGTTCCAGAGCATGCCCAGCTGGGCTGGGTACTTAATTGTTACACCTATTTCGGCGAACTGAGCCGCAT
GACCCAGTTCAAGGATAAATCGGCTCGCTACGCAGAGAACATTAATGCCGGCCTGTTTGATTACCCGGTGCTGATGGCAG
CGGATATCCTGCTGTACCAGACTCACCAGGTCCCGGTAGGGGAAGATCAGAAACAGCACCTGGAGCTGAGCCGTGATGTC
GCGGCGCGCTTCAACGCGCTGTATGGCGATATCTTTAAGGTGCCGGAGCCGTTTATTCCCAAGTCAGGTGCGCGCGTCAT
GTCGCTGCTGGAGCCGACCAAAAAGATGTCTAAGTCGGATGAGAACCGCAACAACGTGATCGGTCTGCTGGAAGATCCCA
AGGCGGTGACCAAGAAGATCAAACGCGCGGTGACCGACTCCGATGAGCCGCCGGTCGTGCGTTACGACGTGGTCAATAAG
GCCGGCGTCTCCAATCTGCTGGATATTCTTTCCGGAGTGACCGGTAAACGTATCGGGGATCTGGAGGCTGAGTTTGCGGG
CAAGATGTACGGCCACCTGAAGGGCGCCGTTGCCGATGCGGTCTCCGGGATGCTGTCTGAGCTGCAGGAGCGGTATCACC
GTTTCCGCAATGATGAGGCCTACCTGCAGGAAGTGATGCGCGATGGCGCCGCCAAAGCGCGCGCGCGCGCCGCACAGACC
CTGGACAAGGTTTACGATGCGATCGGGTTTGTCGCGCGGCCGTAA

Upstream 100 bases:

>100_bases
TGCCAGCGAGCCCTGCTGCGTGCTGGATGACTTTGCCGGCCTGCTGCCCTTGGTAGGGTTGGCGCCGCTGAACTGAATTG
ATAAGGACAGGAATGTGACC

Downstream 100 bases:

>100_bases
GCAGCGCGGCGATCTGAACGTGAAGGGGAGGGCGATGGCCCTCCTTTTTTTGTGCTGTGGCGCTGTGTTATGCGCTTGCC
GCTTCGCAGCGGAACCAGTT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSKPIVFSGAQPSGELTIGNYMGALRQWVQMQDEYDCIYCIVDQHAITVRQDAEKLRSATLDTLALYLACGIDPQKSTIF
VQSHVPEHAQLGWVLNCYTYFGELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTHQVPVGEDQKQHLELSRDV
AARFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDENRNNVIGLLEDPKAVTKKIKRAVTDSDEPPVVRYDVVNK
AGVSNLLDILSGVTGKRIGDLEAEFAGKMYGHLKGAVADAVSGMLSELQERYHRFRNDEAYLQEVMRDGAAKARARAAQT
LDKVYDAIGFVARP

Sequences:

>Translated_334_residues
MSKPIVFSGAQPSGELTIGNYMGALRQWVQMQDEYDCIYCIVDQHAITVRQDAEKLRSATLDTLALYLACGIDPQKSTIF
VQSHVPEHAQLGWVLNCYTYFGELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTHQVPVGEDQKQHLELSRDV
AARFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDENRNNVIGLLEDPKAVTKKIKRAVTDSDEPPVVRYDVVNK
AGVSNLLDILSGVTGKRIGDLEAEFAGKMYGHLKGAVADAVSGMLSELQERYHRFRNDEAYLQEVMRDGAAKARARAAQT
LDKVYDAIGFVARP
>Mature_333_residues
SKPIVFSGAQPSGELTIGNYMGALRQWVQMQDEYDCIYCIVDQHAITVRQDAEKLRSATLDTLALYLACGIDPQKSTIFV
QSHVPEHAQLGWVLNCYTYFGELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTHQVPVGEDQKQHLELSRDVA
ARFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDENRNNVIGLLEDPKAVTKKIKRAVTDSDEPPVVRYDVVNKA
GVSNLLDILSGVTGKRIGDLEAEFAGKMYGHLKGAVADAVSGMLSELQERYHRFRNDEAYLQEVMRDGAAKARARAAQTL
DKVYDAIGFVARP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=42.9003021148036, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=52.5139664804469, Blast_Score=197, Evalue=8e-51,
Organism=Escherichia coli, GI1789786, Length=334, Percent_Identity=88.3233532934132, Blast_Score=626, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=35.9281437125749, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=35.9281437125749, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320474, Length=349, Percent_Identity=39.8280802292264, Blast_Score=239, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24666151, Length=332, Percent_Identity=44.8795180722892, Blast_Score=258, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37245; Mature: 37114

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIVFSGAQPSGELTIGNYMGALRQWVQMQDEYDCIYCIVDQHAITVRQDAEKLRSAT
CCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LDTLALYLACGIDPQKSTIFVQSHVPEHAQLGWVLNCYTYFGELSRMTQFKDKSARYAEN
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INAGLFDYPVLMAADILLYQTHQVPVGEDQKQHLELSRDVAARFNALYGDIFKVPEPFIP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KSGARVMSLLEPTKKMSKSDENRNNVIGLLEDPKAVTKKIKRAVTDSDEPPVVRYDVVNK
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCC
AGVSNLLDILSGVTGKRIGDLEAEFAGKMYGHLKGAVADAVSGMLSELQERYHRFRNDEA
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YLQEVMRDGAAKARARAAQTLDKVYDAIGFVARP
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKPIVFSGAQPSGELTIGNYMGALRQWVQMQDEYDCIYCIVDQHAITVRQDAEKLRSAT
CCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LDTLALYLACGIDPQKSTIFVQSHVPEHAQLGWVLNCYTYFGELSRMTQFKDKSARYAEN
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INAGLFDYPVLMAADILLYQTHQVPVGEDQKQHLELSRDVAARFNALYGDIFKVPEPFIP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KSGARVMSLLEPTKKMSKSDENRNNVIGLLEDPKAVTKKIKRAVTDSDEPPVVRYDVVNK
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCC
AGVSNLLDILSGVTGKRIGDLEAEFAGKMYGHLKGAVADAVSGMLSELQERYHRFRNDEA
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YLQEVMRDGAAKARARAAQTLDKVYDAIGFVARP
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]