Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 238921200

GI number: 238921200

Start: 3227351

End: 3228250

Strand: Reverse

Name: xerD [H]

Synonym: NT01EI_3342

Alternate gene names: 238921200

Gene position: 3228250-3227351 (Counterclockwise)

Preceding gene: 238921202

Following gene: 238921199

Centisome position: 84.68

GC content: 60.22

Gene sequence:

>900_bases
GTGCACGAGCAGGATCAGGCGTTGATCGAACAATTTTTGGATGCGCTGTGGCTGGAGAAGAATCTGGCGGAGAATACCCT
GGCCTCCTATCGTCAGGATCTGCGCACGCTGGCCGAATGGCTGGCCTGTCACGATCTTACTCTGCTGACGGCGGCGCACG
GCGATCTGCAGGACTTCTTTGCCCAACGTATGGATGGGGGCTATAAGGCGTCCAGCTCGGCCCGTCTGCTCAGCGCGCTG
CGCCGCTGTTACCAGTATCTGTACCGGGAGACGCTGCGCGGAGACGATCCGAGCGCGTTGCTGGCCTCGCCCAAACTGCC
GCAACGGTTGCCGAAAGATCTTTCTGAAGCCCAGGTGGATGCCCTGCTGCAGGCGCCCTCCATTGATACGCCGCTGGAGC
TGCGTGATAAGGCGATGCTGGAGCTGCTGTACGCCACCGGCCTGCGGGTGTCCGAACTGGTGGGGCTGGCGCAGGAGGAT
ATCAGCCTGCGTCAGGGCGTGGTACGGGTGATCGGCAAAGGCAATAAAGAGCGCCTGGTTCCCCTTGGGGAGGAGGCTAT
CTACTGGATTGAGTACTATCTGGAGTATGGCCGTCCGTGGCTGGTGAACGGCCAGACGGTAGCGGCGCTGTTTCCCAGCA
ATCGCGCCCGCCAGATGACGCGCCAGACTTTCTGGCATCGGATTAAGCACTATGCTGTCCTGGCGGGGATCGATGGGGAT
CGCCTGTCACCGCACGTGCTGCGCCATGCGTTTGCCACCCATCTGTTGAACCATGGCGCGGATTTACGTGTCGTACAGAT
GCTTTTGGGGCACAGCGATCTTTCTACTACCCAGATTTATACCCATGTAGCGACAGAGCGTCTGCGACAGCTACATCAAC
AGCATCATCCCCGCGCCTGA

Upstream 100 bases:

>100_bases
CTGACCGCATCCTGTAGGCTGGCCGTCGATAAGGCGCCGCACGCAACATGCTGCGTGCAGGCGGAATACCATACAGCGAT
ACCATGGGTAAGGAGCAGGG

Downstream 100 bases:

>100_bases
GCGGAGGGCAATTCAAAGGAATTCATTATGAAGAAAAGCGTGATTTGGTTGGCATTACTGGCGGCGTCCGTCAGCGGCCT
GGCCCGGGCAGATGATGCCG

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MHEQDQALIEQFLDALWLEKNLAENTLASYRQDLRTLAEWLACHDLTLLTAAHGDLQDFFAQRMDGGYKASSSARLLSAL
RRCYQYLYRETLRGDDPSALLASPKLPQRLPKDLSEAQVDALLQAPSIDTPLELRDKAMLELLYATGLRVSELVGLAQED
ISLRQGVVRVIGKGNKERLVPLGEEAIYWIEYYLEYGRPWLVNGQTVAALFPSNRARQMTRQTFWHRIKHYAVLAGIDGD
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA

Sequences:

>Translated_299_residues
MHEQDQALIEQFLDALWLEKNLAENTLASYRQDLRTLAEWLACHDLTLLTAAHGDLQDFFAQRMDGGYKASSSARLLSAL
RRCYQYLYRETLRGDDPSALLASPKLPQRLPKDLSEAQVDALLQAPSIDTPLELRDKAMLELLYATGLRVSELVGLAQED
ISLRQGVVRVIGKGNKERLVPLGEEAIYWIEYYLEYGRPWLVNGQTVAALFPSNRARQMTRQTFWHRIKHYAVLAGIDGD
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA
>Mature_299_residues
MHEQDQALIEQFLDALWLEKNLAENTLASYRQDLRTLAEWLACHDLTLLTAAHGDLQDFFAQRMDGGYKASSSARLLSAL
RRCYQYLYRETLRGDDPSALLASPKLPQRLPKDLSEAQVDALLQAPSIDTPLELRDKAMLELLYATGLRVSELVGLAQED
ISLRQGVVRVIGKGNKERLVPLGEEAIYWIEYYLEYGRPWLVNGQTVAALFPSNRARQMTRQTFWHRIKHYAVLAGIDGD
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region, forming

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=81.4814814814815, Blast_Score=493, Evalue=1e-141,
Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=36.6666666666667, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34088; Mature: 34088

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEQDQALIEQFLDALWLEKNLAENTLASYRQDLRTLAEWLACHDLTLLTAAHGDLQDFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AQRMDGGYKASSSARLLSALRRCYQYLYRETLRGDDPSALLASPKLPQRLPKDLSEAQVD
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHH
ALLQAPSIDTPLELRDKAMLELLYATGLRVSELVGLAQEDISLRQGVVRVIGKGNKERLV
HHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PLGEEAIYWIEYYLEYGRPWLVNGQTVAALFPSNRARQMTRQTFWHRIKHYAVLAGIDGD
CCCHHHHHHHHHHHHHCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCC
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHEQDQALIEQFLDALWLEKNLAENTLASYRQDLRTLAEWLACHDLTLLTAAHGDLQDFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AQRMDGGYKASSSARLLSALRRCYQYLYRETLRGDDPSALLASPKLPQRLPKDLSEAQVD
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHH
ALLQAPSIDTPLELRDKAMLELLYATGLRVSELVGLAQEDISLRQGVVRVIGKGNKERLV
HHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PLGEEAIYWIEYYLEYGRPWLVNGQTVAALFPSNRARQMTRQTFWHRIKHYAVLAGIDGD
CCCHHHHHHHHHHHHHCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCC
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]