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The map label for this gene is cpg2 [H]

Identifier: 238920893

GI number: 238920893

Start: 2906160

End: 2907275

Strand: Direct

Name: cpg2 [H]

Synonym: NT01EI_3020

Alternate gene names: 238920893

Gene position: 2906160-2907275 (Clockwise)

Preceding gene: 238920892

Following gene: 238920894

Centisome position: 76.23

GC content: 66.4

Gene sequence:

>1116_bases
ATGATACAACTGGAACAGTATCTGGACGAACTGCGCAGCGTAGTCAACGTCGACTGCGGTACCCAGACCCGCGACGGGGT
CGCCCGGGTCGCTGATGTCTTTACCGGCCTGTACCGCGACGCTGGCTGGCACGCGGAGCAGGTCGATCTGGGCGACCAGG
TCGGGCCGGGGGTCTTTGTCACCAATCAGCCGCAAGCCGATCGCTACGATGTGCTGCTGGTCGGCCATCTGGACACCGTC
TTCCCACCGGGCACCGCCGCCGAGCGTCCGCTGAGCGTACGTGATGGCCGCGCCTACGGGCCGGGCGTCTCGGATATGAA
GAGCGGTCTGCTCAATATACTGTGGGCACTACGTGGTCTGGAAGAGAGCGATCGTCAGCGCCTGCGCATCGCCGTCGCCA
TGAACCCGGATGAAGAGACCGGTTCCGTCCACTCCCACGCCTGGATTGGCGAGCTGGCCAAGCGCAGCGGCTGTGTTCTG
GTGTGTGAATCAGCGCGTGCCGATGGATCCCTGGTCAAGGCCCGGAAAGGCATGGCCCGCTATCGCCTCAGCTTGCAGGG
CGTCGCCGCCCACGCCGGCAACGATCCGGAGAGGGGACGCTCGGCGATCACCGCCCTGGCCCACGCCATCATCGCCGTCA
ACCAACTGGCGGACAGCGACAAGGGCACCACACTCAACGTCGGGGTGATCAGCGGCGGCGACGCGGCGAACATCGTGCCC
GACCACGCTCAGGCAGTGGTCGATCTGCGCTTCTGGTGCAACGATGAGTATCAGCGCGTCAATCAGGCGCTGCAGGCCCG
CTGTCAGCAGCCGTTCCTGGACGGCGTCAGCTGCACGCTGCAGCAGGATGCCCACACCCCGGCCATGGCGCCGTCAAGCG
ATACCGAAGCCCTGATGGCCCGCGTCGAACAGGCCGGGCGGGAAGAGGGGATCGCCATCACCTGGCAGGCGGTGGGCGGC
GGCTCTGATGCCAACCACACCGCGGCGCTGGGGATCCCGTCACTGGATGGCTTTGGCCCTATCGGTGCCGGTTTCCACAG
CCCGGCCGAATACCTGGAGCTGGAGAGCGTCGCCCCGCGCATTCGTCTGCTACGCCGGGTGATCGCCGGGCTGTAA

Upstream 100 bases:

>100_bases
GCCGCCAAACGTATTCCGGTGATGATCGGCATCTCCGTCATCAACGCCTTCATCGCCATGCTGCTCATGCGCGTAATTCT
GTAACTCAGGGAGAGATAGG

Downstream 100 bases:

>100_bases
CGCTCTACTGTGTCATACCCCAAGGGGCCGCACTCTGCGGCCCCTTATTTTTATCATCTTAATGCCCGGTAAACTTCACC
GGCAACCTGAGACACTGGTT

Product: carboxypeptidase family

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MIQLEQYLDELRSVVNVDCGTQTRDGVARVADVFTGLYRDAGWHAEQVDLGDQVGPGVFVTNQPQADRYDVLLVGHLDTV
FPPGTAAERPLSVRDGRAYGPGVSDMKSGLLNILWALRGLEESDRQRLRIAVAMNPDEETGSVHSHAWIGELAKRSGCVL
VCESARADGSLVKARKGMARYRLSLQGVAAHAGNDPERGRSAITALAHAIIAVNQLADSDKGTTLNVGVISGGDAANIVP
DHAQAVVDLRFWCNDEYQRVNQALQARCQQPFLDGVSCTLQQDAHTPAMAPSSDTEALMARVEQAGREEGIAITWQAVGG
GSDANHTAALGIPSLDGFGPIGAGFHSPAEYLELESVAPRIRLLRRVIAGL

Sequences:

>Translated_371_residues
MIQLEQYLDELRSVVNVDCGTQTRDGVARVADVFTGLYRDAGWHAEQVDLGDQVGPGVFVTNQPQADRYDVLLVGHLDTV
FPPGTAAERPLSVRDGRAYGPGVSDMKSGLLNILWALRGLEESDRQRLRIAVAMNPDEETGSVHSHAWIGELAKRSGCVL
VCESARADGSLVKARKGMARYRLSLQGVAAHAGNDPERGRSAITALAHAIIAVNQLADSDKGTTLNVGVISGGDAANIVP
DHAQAVVDLRFWCNDEYQRVNQALQARCQQPFLDGVSCTLQQDAHTPAMAPSSDTEALMARVEQAGREEGIAITWQAVGG
GSDANHTAALGIPSLDGFGPIGAGFHSPAEYLELESVAPRIRLLRRVIAGL
>Mature_371_residues
MIQLEQYLDELRSVVNVDCGTQTRDGVARVADVFTGLYRDAGWHAEQVDLGDQVGPGVFVTNQPQADRYDVLLVGHLDTV
FPPGTAAERPLSVRDGRAYGPGVSDMKSGLLNILWALRGLEESDRQRLRIAVAMNPDEETGSVHSHAWIGELAKRSGCVL
VCESARADGSLVKARKGMARYRLSLQGVAAHAGNDPERGRSAITALAHAIIAVNQLADSDKGTTLNVGVISGGDAANIVP
DHAQAVVDLRFWCNDEYQRVNQALQARCQQPFLDGVSCTLQQDAHTPAMAPSSDTEALMARVEQAGREEGIAITWQAVGG
GSDANHTAALGIPSLDGFGPIGAGFHSPAEYLELESVAPRIRLLRRVIAGL

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=316, Percent_Identity=28.4810126582279, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 39629; Mature: 39629

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLEQYLDELRSVVNVDCGTQTRDGVARVADVFTGLYRDAGWHAEQVDLGDQVGPGVFV
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEE
TNQPQADRYDVLLVGHLDTVFPPGTAAERPLSVRDGRAYGPGVSDMKSGLLNILWALRGL
ECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
EESDRQRLRIAVAMNPDEETGSVHSHAWIGELAKRSGCVLVCESARADGSLVKARKGMAR
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHH
YRLSLQGVAAHAGNDPERGRSAITALAHAIIAVNQLADSDKGTTLNVGVISGGDAANIVP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCC
DHAQAVVDLRFWCNDEYQRVNQALQARCQQPFLDGVSCTLQQDAHTPAMAPSSDTEALMA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
RVEQAGREEGIAITWQAVGGGSDANHTAALGIPSLDGFGPIGAGFHSPAEYLELESVAPR
HHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IRLLRRVIAGL
HHHHHHHHHCC
>Mature Secondary Structure
MIQLEQYLDELRSVVNVDCGTQTRDGVARVADVFTGLYRDAGWHAEQVDLGDQVGPGVFV
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEE
TNQPQADRYDVLLVGHLDTVFPPGTAAERPLSVRDGRAYGPGVSDMKSGLLNILWALRGL
ECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
EESDRQRLRIAVAMNPDEETGSVHSHAWIGELAKRSGCVLVCESARADGSLVKARKGMAR
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHH
YRLSLQGVAAHAGNDPERGRSAITALAHAIIAVNQLADSDKGTTLNVGVISGGDAANIVP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCC
DHAQAVVDLRFWCNDEYQRVNQALQARCQQPFLDGVSCTLQQDAHTPAMAPSSDTEALMA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
RVEQAGREEGIAITWQAVGGGSDANHTAALGIPSLDGFGPIGAGFHSPAEYLELESVAPR
HHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IRLLRRVIAGL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]