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The map label for this gene is hgdC [H]

Identifier: 238917564

GI number: 238917564

Start: 1703522

End: 1704352

Strand: Reverse

Name: hgdC [H]

Synonym: EUBELI_01643

Alternate gene names: 238917564

Gene position: 1704352-1703522 (Counterclockwise)

Preceding gene: 238917565

Following gene: 238917563

Centisome position: 79.49

GC content: 43.92

Gene sequence:

>831_bases
GTGTATGCTGCATACGTGGCAGGAAAGGATAGCAGAATGAAATATTTCGGTGGTTGTGACGCAGGAAGTACATATACCAA
ATGCGTAATTATAGATGAGAATGGAAAAATCGCAGCTGCGGTTACTAAGAGAAGCAGGATTAATCCTGTACTTAGTGCGA
AGGATGCACTTGACGAGGCTGTAAGCCAGGTTGACGGTTTAAACAGCGCAGAGGAGCTTACATATCTGATTGGTACGGGT
TACGGAAGAAACAAAGTACCGTTTGCAGATGAGAATATATCAGAGATAAGCTGTCATGCTATGGGAGTTCATGTGACTGA
CCCATCGGTTAAGGCGATTATTGATATCGGCGGTCAGGATGTTAAGGGAATTGCGATTGACACAGATGGAACTGTGCTTA
ATTTTGCGATGAATGACAAATGTGCAGCAGGAACGGGAAGATTTTTTGAATCTATGGCAAGAGCATTTGAGATGTCTTTA
GATGAATTTTCTAATCTGTCACTTACGGCGAAGAACGTGATTCCAATAACAGCACAGTGCGCGGTATTTGCAGAGAGTGA
GGTTATCTCGTTAGTAGGTGAGGGTAAGCCTATGGAGGAGATAGCGGCAGGAATACAGTTATCGGTTGCTAAGAGATGCT
TTGTCATGGCTAAGAAAGCAGGTGCGGCTGACAGCGTTACACTTACAGGTGGATGTGCCAAGAATGAAGGCTTGAAGAAA
GCAATAGAGAAGGTTCTTAAGATAAATGTAGTGGATCTGCCGACAGACCCACAGCTTATGGGAGCATTAGGTGCTGCAGA
ATATGCAAGACAGAAGGGAAGTAATGTATGA

Upstream 100 bases:

>100_bases
TGAGAACGGAGATTAACAGATATATGAGAACTGTTTTCAGGGAAGAACCGCTTGACCCATCACTTGAGGATTTTGACGAT
TCTAAGAGCTGGTAAGAAGT

Downstream 100 bases:

>100_bases
TAGTATTAAAAGTGCTGGCAATTATAGCAATCGTGCTTGTTGTGCTTTTTTTTCTCACTCTTGTTATATATTTCTTTAAT
CTTGATATGAAGTTTGCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MYAAYVAGKDSRMKYFGGCDAGSTYTKCVIIDENGKIAAAVTKRSRINPVLSAKDALDEAVSQVDGLNSAEELTYLIGTG
YGRNKVPFADENISEISCHAMGVHVTDPSVKAIIDIGGQDVKGIAIDTDGTVLNFAMNDKCAAGTGRFFESMARAFEMSL
DEFSNLSLTAKNVIPITAQCAVFAESEVISLVGEGKPMEEIAAGIQLSVAKRCFVMAKKAGAADSVTLTGGCAKNEGLKK
AIEKVLKINVVDLPTDPQLMGALGAAEYARQKGSNV

Sequences:

>Translated_276_residues
MYAAYVAGKDSRMKYFGGCDAGSTYTKCVIIDENGKIAAAVTKRSRINPVLSAKDALDEAVSQVDGLNSAEELTYLIGTG
YGRNKVPFADENISEISCHAMGVHVTDPSVKAIIDIGGQDVKGIAIDTDGTVLNFAMNDKCAAGTGRFFESMARAFEMSL
DEFSNLSLTAKNVIPITAQCAVFAESEVISLVGEGKPMEEIAAGIQLSVAKRCFVMAKKAGAADSVTLTGGCAKNEGLKK
AIEKVLKINVVDLPTDPQLMGALGAAEYARQKGSNV
>Mature_276_residues
MYAAYVAGKDSRMKYFGGCDAGSTYTKCVIIDENGKIAAAVTKRSRINPVLSAKDALDEAVSQVDGLNSAEELTYLIGTG
YGRNKVPFADENISEISCHAMGVHVTDPSVKAIIDIGGQDVKGIAIDTDGTVLNFAMNDKCAAGTGRFFESMARAFEMSL
DEFSNLSLTAKNVIPITAQCAVFAESEVISLVGEGKPMEEIAAGIQLSVAKRCFVMAKKAGAADSVTLTGGCAKNEGLKK
AIEKVLKINVVDLPTDPQLMGALGAAEYARQKGSNV

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=257, Percent_Identity=38.5214007782101, Blast_Score=165, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 29022; Mature: 29022

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAAYVAGKDSRMKYFGGCDAGSTYTKCVIIDENGKIAAAVTKRSRINPVLSAKDALDEA
CEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCEEEEEECCHHCCCHHHHHHHHHHH
VSQVDGLNSAEELTYLIGTGYGRNKVPFADENISEISCHAMGVHVTDPSVKAIIDIGGQD
HHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEECCCC
VKGIAIDTDGTVLNFAMNDKCAAGTGRFFESMARAFEMSLDEFSNLSLTAKNVIPITAQC
CEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEEEE
AVFAESEVISLVGEGKPMEEIAAGIQLSVAKRCFVMAKKAGAADSVTLTGGCAKNEGLKK
EEEECCHHHEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
AIEKVLKINVVDLPTDPQLMGALGAAEYARQKGSNV
HHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYAAYVAGKDSRMKYFGGCDAGSTYTKCVIIDENGKIAAAVTKRSRINPVLSAKDALDEA
CEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCEEEEEECCHHCCCHHHHHHHHHHH
VSQVDGLNSAEELTYLIGTGYGRNKVPFADENISEISCHAMGVHVTDPSVKAIIDIGGQD
HHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEECCCC
VKGIAIDTDGTVLNFAMNDKCAAGTGRFFESMARAFEMSLDEFSNLSLTAKNVIPITAQC
CEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEEEE
AVFAESEVISLVGEGKPMEEIAAGIQLSVAKRCFVMAKKAGAADSVTLTGGCAKNEGLKK
EEEECCHHHEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
AIEKVLKINVVDLPTDPQLMGALGAAEYARQKGSNV
HHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]