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The map label for this gene is yrbE [H]

Identifier: 238896701

GI number: 238896701

Start: 4678403

End: 4679185

Strand: Reverse

Name: yrbE [H]

Synonym: KP1_4916

Alternate gene names: 238896701

Gene position: 4679185-4678403 (Counterclockwise)

Preceding gene: 238896702

Following gene: 238896700

Centisome position: 89.15

GC content: 58.37

Gene sequence:

>783_bases
ATGCTGTTTAATGCGCTGGCCGCGCTAGGTCATCGCGGTATTAAAACCACCGCGACGTTTGGACGCGCCGGATTAATGCT
TTTCAACGCCGTTGTCGGCAAACCAGAGTTTCGCAAGCACGCGCCGCTGCTGGTTCGTCAACTCTATAACGTCGGCGTCC
TGTCGATGCTGATTATCATTGTATCGGGCTTGTTTATCGGTATGGTGCTCGGGCTGCAGGGGTATCTGGTGTTAACCACC
TACAGCGCAGAGACCAGTCTTGGCATGCTGGTGGCGCTGTCGCTGCTGCGTGAGCTGGGGCCGGTGGTCGCCGCGCTGCT
GTTTGCCGGCCGCGCCGGGTCGGCGCTGACCGCCGAGATTGGCCTGATGCGGGCCACGGAACAGCTCTCCAGTATGGAGA
TGATGGCGGTGGATCCGCTGCGTCGCGTCATTTCCCCACGCTTCTGGGCCGGTGTCATTTCGCTGCCGCTGCTGACGATT
ATCTTCGTCGCGGTAGGGATCTGGGGCGGTGCGCTGGTGGGTGTGAGCTGGAAAGGCATTGACGGTGGTTTTTTCTGGAC
CGCGATGCAAAATGCCGTCGACTGGCGAATGGATCTGGTGAACTGCCTGATTAAGAGTCTGGTGTTCGCTATTACGGTAA
CCTGGATTGCGTTATTTAATGGTTATGACGCTATCCCCACTTCCGCCGGGATTAGCCGGGCGACAACGCGTACCGTGGTG
CATGCGTCGCTGGCGGTTCTGGGGCTGGATTTTGTGCTGACTGCGCTGATGTTTGGGAATTGA

Upstream 100 bases:

>100_bases
CGTCAGTTCATTGATGGTATTGCCGACGGTCCGGTGCCGTTCCGTTATCCTGCTGGCGACTATCACCATGATTTATTAGG
CATAGGGAGTTGAGCGACTC

Downstream 100 bases:

>100_bases
GTTCATGCAAACGAAAAAAACTGAAATCTGGGTAGGGGTGTTCTTACTGGTGGCGCTGCTGGCGGCGCTGTTTGTCTGCC
TGAAGGCGGCGAACGTCACC

Product: putative ABC transport system permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLFNALAALGHRGIKTTATFGRAGLMLFNAVVGKPEFRKHAPLLVRQLYNVGVLSMLIIIVSGLFIGMVLGLQGYLVLTT
YSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTI
IFVAVGIWGGALVGVSWKGIDGGFFWTAMQNAVDWRMDLVNCLIKSLVFAITVTWIALFNGYDAIPTSAGISRATTRTVV
HASLAVLGLDFVLTALMFGN

Sequences:

>Translated_260_residues
MLFNALAALGHRGIKTTATFGRAGLMLFNAVVGKPEFRKHAPLLVRQLYNVGVLSMLIIIVSGLFIGMVLGLQGYLVLTT
YSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTI
IFVAVGIWGGALVGVSWKGIDGGFFWTAMQNAVDWRMDLVNCLIKSLVFAITVTWIALFNGYDAIPTSAGISRATTRTVV
HASLAVLGLDFVLTALMFGN
>Mature_260_residues
MLFNALAALGHRGIKTTATFGRAGLMLFNAVVGKPEFRKHAPLLVRQLYNVGVLSMLIIIVSGLFIGMVLGLQGYLVLTT
YSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTI
IFVAVGIWGGALVGVSWKGIDGGFFWTAMQNAVDWRMDLVNCLIKSLVFAITVTWIALFNGYDAIPTSAGISRATTRTVV
HASLAVLGLDFVLTALMFGN

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG0767

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaE permease family [H]

Homologues:

Organism=Escherichia coli, GI1789585, Length=260, Percent_Identity=94.2307692307692, Blast_Score=491, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003453 [H]

Pfam domain/function: PF02405 DUF140 [H]

EC number: NA

Molecular weight: Translated: 27791; Mature: 27791

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNALAALGHRGIKTTATFGRAGLMLFNAVVGKPEFRKHAPLLVRQLYNVGVLSMLIII
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSGLFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEI
HHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTIIFVAVGIWGGALVGVSWKGI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEECC
DGGFFWTAMQNAVDWRMDLVNCLIKSLVFAITVTWIALFNGYDAIPTSAGISRATTRTVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
HASLAVLGLDFVLTALMFGN
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFNALAALGHRGIKTTATFGRAGLMLFNAVVGKPEFRKHAPLLVRQLYNVGVLSMLIII
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSGLFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEI
HHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTIIFVAVGIWGGALVGVSWKGI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEECC
DGGFFWTAMQNAVDWRMDLVNCLIKSLVFAITVTWIALFNGYDAIPTSAGISRATTRTVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
HASLAVLGLDFVLTALMFGN
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]