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The map label for this gene is yrbD [H]

Identifier: 238896700

GI number: 238896700

Start: 4677847

End: 4678398

Strand: Reverse

Name: yrbD [H]

Synonym: KP1_4915

Alternate gene names: 238896700

Gene position: 4678398-4677847 (Counterclockwise)

Preceding gene: 238896701

Following gene: 238896699

Centisome position: 89.14

GC content: 57.61

Gene sequence:

>552_bases
ATGCAAACGAAAAAAACTGAAATCTGGGTAGGGGTGTTCTTACTGGTGGCGCTGCTGGCGGCGCTGTTTGTCTGCCTGAA
GGCGGCGAACGTCACCTCGCTACGCACCGAGCCGACTTATCGCCTTTATGCGACTTTCGATAACATCGGCGGCCTGAAGG
CGCGCTCGCCGGTGCGCATCGGCGGCGTGGTAGTGGGGCGGGTAGCGGACATTACGCTCGATCCGAAAACCTATCTGCCA
CGCGTGGAGCTCGATATCGATGAGCGCTACAACCATATCCCGGATACCAGTTCGTTGGCGATCCGCACCTCTGGCCTGCT
GGGCGAGCAGTACCTGGCGCTGAACGTCGGTTTTGAAGACCCGGACCTCGGGACGACTATCCTTAAAGACGGCGGCACTA
TCCAGGACACTAAGTCCGCCATGGTGCTGGAAGATCTGATTGGTCAGTTCCTTTATAACAGTAAGGGCGGCGACAATCAG
AATTCTGGCAATGATAAGGCCGAGGCAGAAGGTCATACTGACGCGACGCCGGCAGCCGGCACGACGCATTAA

Upstream 100 bases:

>100_bases
GGGATTAGCCGGGCGACAACGCGTACCGTGGTGCATGCGTCGCTGGCGGTTCTGGGGCTGGATTTTGTGCTGACTGCGCT
GATGTTTGGGAATTGAGTTC

Downstream 100 bases:

>100_bases
TTTCAGGAGAAATACGATATGTTTAAACGCTTACTCATGGTCGCCATGCTGGTGATTGCCCCGCTGACCGCCGTCCAGGC
CGCAGATCAGTCCAATCCGT

Product: putative ABC transport system periplasmic binding component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MQTKKTEIWVGVFLLVALLAALFVCLKAANVTSLRTEPTYRLYATFDNIGGLKARSPVRIGGVVVGRVADITLDPKTYLP
RVELDIDERYNHIPDTSSLAIRTSGLLGEQYLALNVGFEDPDLGTTILKDGGTIQDTKSAMVLEDLIGQFLYNSKGGDNQ
NSGNDKAEAEGHTDATPAAGTTH

Sequences:

>Translated_183_residues
MQTKKTEIWVGVFLLVALLAALFVCLKAANVTSLRTEPTYRLYATFDNIGGLKARSPVRIGGVVVGRVADITLDPKTYLP
RVELDIDERYNHIPDTSSLAIRTSGLLGEQYLALNVGFEDPDLGTTILKDGGTIQDTKSAMVLEDLIGQFLYNSKGGDNQ
NSGNDKAEAEGHTDATPAAGTTH
>Mature_183_residues
MQTKKTEIWVGVFLLVALLAALFVCLKAANVTSLRTEPTYRLYATFDNIGGLKARSPVRIGGVVVGRVADITLDPKTYLP
RVELDIDERYNHIPDTSSLAIRTSGLLGEQYLALNVGFEDPDLGTTILKDGGTIQDTKSAMVLEDLIGQFLYNSKGGDNQ
NSGNDKAEAEGHTDATPAAGTTH

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG1463

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaD family [H]

Homologues:

Organism=Escherichia coli, GI1789584, Length=183, Percent_Identity=83.6065573770492, Blast_Score=295, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003399 [H]

Pfam domain/function: PF02470 MCE [H]

EC number: NA

Molecular weight: Translated: 19697; Mature: 19697

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKKTEIWVGVFLLVALLAALFVCLKAANVTSLRTEPTYRLYATFDNIGGLKARSPVRI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEECCCCCCCCCCCEEE
GGVVVGRVADITLDPKTYLPRVELDIDERYNHIPDTSSLAIRTSGLLGEQYLALNVGFED
CCEEEEEEEEEEECCHHHCCEEEEEHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCC
PDLGTTILKDGGTIQDTKSAMVLEDLIGQFLYNSKGGDNQNSGNDKAEAEGHTDATPAAG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TTH
CCC
>Mature Secondary Structure
MQTKKTEIWVGVFLLVALLAALFVCLKAANVTSLRTEPTYRLYATFDNIGGLKARSPVRI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEECCCCCCCCCCCEEE
GGVVVGRVADITLDPKTYLPRVELDIDERYNHIPDTSSLAIRTSGLLGEQYLALNVGFED
CCEEEEEEEEEEECCHHHCCEEEEEHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCC
PDLGTTILKDGGTIQDTKSAMVLEDLIGQFLYNSKGGDNQNSGNDKAEAEGHTDATPAAG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TTH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]