| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is hflB [H]
Identifier: 238896685
GI number: 238896685
Start: 4665169
End: 4667103
Strand: Reverse
Name: hflB [H]
Synonym: KP1_4897
Alternate gene names: 238896685
Gene position: 4667103-4665169 (Counterclockwise)
Preceding gene: 238896686
Following gene: 238896684
Centisome position: 88.92
GC content: 56.49
Gene sequence:
>1935_bases ATGGCGAAAAACCTAATACTCTGGCTGGTCATTGCCGTTGTGCTGATGTCAGTATTCCAGAGCTTTGGGCCCAGCGAGTC GAATGGCCGCAAGGTGGATTATTCTACCTTCCTGCAAGAGGTCAATCAGGACCAGGTTCGCGAAGCGCGTATCAACGGAC GTGAGATCAACGTTACCAAGAAAGATAGTAACCGTTACACGACTTACATTCCGGTTAACGATCCGAAGCTGCTCGATAAC CTGTTGACTAAAAACGTCAAAGTTGTTGGCGAACCACCAGAAGAGCCGAGCCTGCTGGCTTCCATCTTCATCTCCTGGTT CCCAATGCTGCTGCTGATCGGCGTCTGGATCTTCTTTATGCGGCAAATGCAGGGCGGCGGCGGGAAGGGCGCGATGTCCT TCGGCAAAAGCAAAGCCCGTATGTTGACGGAAGACCAGATCAAAACCACTTTTGCAGACGTTGCCGGGTGTGACGAAGCG AAAGAGGAAGTCGGCGAGCTGGTAGAATACCTGCGTGAGCCGAGCCGCTTCCAGAAACTGGGCGGTAAAATCCCGAAAGG CGTCCTGATGGTCGGCCCTCCGGGTACCGGTAAAACGCTGCTGGCGAAAGCGATCGCTGGTGAAGCGAAGGTACCGTTCT TTACCATTTCCGGTTCTGACTTCGTCGAAATGTTCGTCGGTGTGGGCGCTTCTCGTGTGCGTGACATGTTCGAACAGGCT AAGAAAGCCGCGCCTTGCATCATCTTCATCGATGAAATCGACGCCGTCGGCCGCCAGCGTGGCGCAGGCCTGGGCGGTGG TCACGATGAACGTGAGCAGACCCTGAACCAGATGCTGGTTGAGATGGACGGCTTCGAAGGTAACGAAGGTATCATCGTTA TCGCGGCGACTAACCGTCCGGACGTTCTTGACCCCGCGCTGTTGCGTCCGGGCCGTTTTGACCGCCAGGTGGTGGTTGGC CTGCCGGATGTTCGCGGTCGTGAGCAGATCCTGAAAGTGCATATGCGTCGCGTTCCGCTGGCGCCGGATATCGATGCGGC AATCATTGCGCGCGGTACCCCGGGCTTCTCCGGTGCGGATCTGGCCAACCTGGTCAACGAAGCGGCGCTGTTTGCTGCCC GCGGTAACAAACGCGTTGTGTCGATGGTTGAGTTCGAGAAAGCGAAAGACAAAATCATGATGGGTGCGGAACGTCGCTCC ATGGTGATGACGGAAGCGCAGAAAGAGTCTACTGCTTATCATGAAGCGGGCCACGCGATTATTGGTCGCCTGGTGCCGGA GCACGATCCGGTGCACAAAGTGACGATTATCCCGCGCGGTCGTGCGCTGGGTGTGACCTTCTTCCTGCCGGAAGGCGATG CAATCAGCGCCAGCCGTCAGAAACTGGAAAGCCAGATCTCCACCCTGTACGGCGGTCGTCTGGCGGAAGAGATTATCTAC GGTCCGGAACATGTTTCTACTGGTGCGTCCAACGATATTAAAGTGGCGACGAACCTGGCGCGTAACATGGTGACCCAGTG GGGCTTCTCCGACAAACTCGGTCCGCTGCTGTATGCGGAAGAAGAGGGTGAAGTCTTCCTCGGCCGTAGCGTCGCGAAAG CGAAGCATATGTCCGATGAAACCGCGCGTATCATCGACCAGGAAGTTAAATCGCTGATTGAGCGTAACTACGGTCGTGCT CGCCAGCTGCTGAACGACAACATGGACATTCTGCACGCGATGAAAGATGCGCTCATGAAGTATGAGACCATCGATGCGCC GCAGATTGACGACCTGATGGCTCGTCGCGAAGTTCGTCCGCCAGCGGGTTGGGAAGAACCTGGTTCTTCTAACAACTCTG ACAACAATGGCACGCCTCGTGCGCCGCGTCCGGTTGATGAACCGCGTACGCCGAACCCGGGCAACACCATGTCAGAGCAG CTGGGCGACAAGTAA
Upstream 100 bases:
>100_bases ACCGGCAGATTTCAAACGAAAGTTTGAAAGAAACTGGATATAGAGTATCCTGACGCTGTTTTTAACACAGTTGTAATAAG AGGTTAATCCCTTGAGTGAC
Downstream 100 bases:
>100_bases GCTACCGCTGTTGATGCTTGTTTAACCTTAAAACCCCGGGCGTCCGCTCCGGGGTTTTTCTTTTTTAACCTCTTCAGTCT CAGGGATTTTGTGATGAAAC
Product: ATP-dependent metalloprotease
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 644; Mature: 643
Protein sequence:
>644_residues MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQDQVREARINGREINVTKKDSNRYTTYIPVNDPKLLDN LLTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA KEEVGELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQA KKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVG LPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRS MVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIY GPEHVSTGASNDIKVATNLARNMVTQWGFSDKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKSLIERNYGRA RQLLNDNMDILHAMKDALMKYETIDAPQIDDLMARREVRPPAGWEEPGSSNNSDNNGTPRAPRPVDEPRTPNPGNTMSEQ LGDK
Sequences:
>Translated_644_residues MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQDQVREARINGREINVTKKDSNRYTTYIPVNDPKLLDN LLTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA KEEVGELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQA KKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVG LPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRS MVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIY GPEHVSTGASNDIKVATNLARNMVTQWGFSDKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKSLIERNYGRA RQLLNDNMDILHAMKDALMKYETIDAPQIDDLMARREVRPPAGWEEPGSSNNSDNNGTPRAPRPVDEPRTPNPGNTMSEQ LGDK >Mature_643_residues AKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQDQVREARINGREINVTKKDSNRYTTYIPVNDPKLLDNL LTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEAK EEVGELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAK KAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGL PDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRSM VMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIYG PEHVSTGASNDIKVATNLARNMVTQWGFSDKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKSLIERNYGRAR QLLNDNMDILHAMKDALMKYETIDAPQIDDLMARREVRPPAGWEEPGSSNNSDNNGTPRAPRPVDEPRTPNPGNTMSEQL GDK
Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]
COG id: COG0465
COG function: function code O; ATP-dependent Zn proteases
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]
Homologues:
Organism=Homo sapiens, GI300192933, Length=518, Percent_Identity=44.980694980695, Blast_Score=443, Evalue=1e-124, Organism=Homo sapiens, GI7657689, Length=452, Percent_Identity=49.7787610619469, Blast_Score=441, Evalue=1e-124, Organism=Homo sapiens, GI21327685, Length=452, Percent_Identity=49.7787610619469, Blast_Score=441, Evalue=1e-124, Organism=Homo sapiens, GI4507173, Length=460, Percent_Identity=41.7391304347826, Blast_Score=364, Evalue=1e-100, Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=42.5196850393701, Blast_Score=219, Evalue=8e-57, Organism=Homo sapiens, GI24497435, Length=269, Percent_Identity=41.2639405204461, Blast_Score=208, Evalue=1e-53, Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=43.8053097345133, Blast_Score=207, Evalue=2e-53, Organism=Homo sapiens, GI24430151, Length=254, Percent_Identity=39.7637795275591, Blast_Score=202, Evalue=1e-51, Organism=Homo sapiens, GI195539395, Length=253, Percent_Identity=41.501976284585, Blast_Score=201, Evalue=1e-51, Organism=Homo sapiens, GI21361144, Length=228, Percent_Identity=44.2982456140351, Blast_Score=200, Evalue=3e-51, Organism=Homo sapiens, GI89064750, Length=264, Percent_Identity=41.2878787878788, Blast_Score=196, Evalue=4e-50, Organism=Homo sapiens, GI5729991, Length=264, Percent_Identity=41.2878787878788, Blast_Score=196, Evalue=6e-50, Organism=Homo sapiens, GI24430155, Length=264, Percent_Identity=41.2878787878788, Blast_Score=196, Evalue=6e-50, Organism=Homo sapiens, GI45643123, Length=280, Percent_Identity=38.5714285714286, Blast_Score=191, Evalue=2e-48, Organism=Homo sapiens, GI45643125, Length=280, Percent_Identity=38.5714285714286, Blast_Score=190, Evalue=3e-48, Organism=Homo sapiens, GI157671927, Length=237, Percent_Identity=39.2405063291139, Blast_Score=181, Evalue=2e-45, Organism=Homo sapiens, GI4505725, Length=213, Percent_Identity=41.3145539906103, Blast_Score=175, Evalue=1e-43, Organism=Homo sapiens, GI40806173, Length=137, Percent_Identity=59.1240875912409, Blast_Score=172, Evalue=7e-43, Organism=Homo sapiens, GI229577436, Length=256, Percent_Identity=38.28125, Blast_Score=167, Evalue=3e-41, Organism=Homo sapiens, GI5901990, Length=233, Percent_Identity=40.7725321888412, Blast_Score=161, Evalue=2e-39, Organism=Homo sapiens, GI194018488, Length=255, Percent_Identity=38.4313725490196, Blast_Score=157, Evalue=2e-38, Organism=Homo sapiens, GI153792536, Length=231, Percent_Identity=39.3939393939394, Blast_Score=157, Evalue=4e-38, Organism=Homo sapiens, GI24497618, Length=231, Percent_Identity=39.3939393939394, Blast_Score=156, Evalue=5e-38, Organism=Homo sapiens, GI14149767, Length=273, Percent_Identity=36.996336996337, Blast_Score=155, Evalue=1e-37, Organism=Homo sapiens, GI62177112, Length=273, Percent_Identity=36.996336996337, Blast_Score=155, Evalue=1e-37, Organism=Homo sapiens, GI226371754, Length=234, Percent_Identity=38.034188034188, Blast_Score=150, Evalue=3e-36, Organism=Homo sapiens, GI156564401, Length=235, Percent_Identity=39.1489361702128, Blast_Score=143, Evalue=5e-34, Organism=Homo sapiens, GI310125282, Length=235, Percent_Identity=38.7234042553192, Blast_Score=139, Evalue=7e-33, Organism=Homo sapiens, GI310125280, Length=235, Percent_Identity=38.7234042553192, Blast_Score=139, Evalue=7e-33, Organism=Homo sapiens, GI7019569, Length=248, Percent_Identity=36.6935483870968, Blast_Score=138, Evalue=2e-32, Organism=Homo sapiens, GI11875211, Length=227, Percent_Identity=40.9691629955947, Blast_Score=137, Evalue=3e-32, Organism=Homo sapiens, GI40806170, Length=227, Percent_Identity=40.9691629955947, Blast_Score=137, Evalue=4e-32, Organism=Homo sapiens, GI31742536, Length=254, Percent_Identity=34.6456692913386, Blast_Score=135, Evalue=9e-32, Organism=Homo sapiens, GI112789543, Length=254, Percent_Identity=34.6456692913386, Blast_Score=135, Evalue=9e-32, Organism=Homo sapiens, GI17865802, Length=250, Percent_Identity=37.2, Blast_Score=134, Evalue=2e-31, Organism=Homo sapiens, GI31377644, Length=238, Percent_Identity=34.8739495798319, Blast_Score=127, Evalue=2e-29, Organism=Homo sapiens, GI64084766, Length=318, Percent_Identity=27.9874213836478, Blast_Score=101, Evalue=2e-21, Organism=Homo sapiens, GI116292174, Length=248, Percent_Identity=30.6451612903226, Blast_Score=82, Evalue=1e-15, Organism=Homo sapiens, GI75677353, Length=196, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=4e-12, Organism=Homo sapiens, GI283436222, Length=207, Percent_Identity=28.9855072463768, Blast_Score=70, Evalue=6e-12, Organism=Homo sapiens, GI283436220, Length=207, Percent_Identity=28.9855072463768, Blast_Score=70, Evalue=6e-12, Organism=Homo sapiens, GI283436224, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=7e-12, Organism=Escherichia coli, GI1789568, Length=644, Percent_Identity=97.9813664596273, Blast_Score=1293, Evalue=0.0, Organism=Caenorhabditis elegans, GI71994521, Length=478, Percent_Identity=47.489539748954, Blast_Score=420, Evalue=1e-117, Organism=Caenorhabditis elegans, GI17554264, Length=484, Percent_Identity=44.4214876033058, Blast_Score=410, Evalue=1e-114, Organism=Caenorhabditis elegans, GI115534323, Length=459, Percent_Identity=43.7908496732026, Blast_Score=363, Evalue=1e-100, Organism=Caenorhabditis elegans, GI17554786, Length=262, Percent_Identity=43.8931297709924, Blast_Score=222, Evalue=4e-58, Organism=Caenorhabditis elegans, GI17563248, Length=261, Percent_Identity=42.5287356321839, Blast_Score=219, Evalue=4e-57, Organism=Caenorhabditis elegans, GI17532375, Length=335, Percent_Identity=37.3134328358209, Blast_Score=218, Evalue=7e-57, Organism=Caenorhabditis elegans, GI25144278, Length=262, Percent_Identity=43.5114503816794, Blast_Score=215, Evalue=6e-56, Organism=Caenorhabditis elegans, GI25144281, Length=262, Percent_Identity=43.5114503816794, Blast_Score=215, Evalue=7e-56, Organism=Caenorhabditis elegans, GI17531535, Length=245, Percent_Identity=43.6734693877551, Blast_Score=206, Evalue=4e-53, Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=41.7322834645669, Blast_Score=204, Evalue=9e-53, Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=41.7322834645669, Blast_Score=204, Evalue=1e-52, Organism=Caenorhabditis elegans, GI17508701, Length=228, Percent_Identity=44.2982456140351, Blast_Score=197, Evalue=1e-50, Organism=Caenorhabditis elegans, GI17563250, Length=254, Percent_Identity=39.3700787401575, Blast_Score=197, Evalue=1e-50, Organism=Caenorhabditis elegans, GI17505546, Length=248, Percent_Identity=40.3225806451613, Blast_Score=192, Evalue=6e-49, Organism=Caenorhabditis elegans, GI17554784, Length=259, Percent_Identity=40.9266409266409, Blast_Score=180, Evalue=2e-45, Organism=Caenorhabditis elegans, GI17508053, Length=243, Percent_Identity=39.5061728395062, Blast_Score=179, Evalue=3e-45, Organism=Caenorhabditis elegans, GI17537217, Length=257, Percent_Identity=37.7431906614786, Blast_Score=164, Evalue=1e-40, Organism=Caenorhabditis elegans, GI25153574, Length=249, Percent_Identity=36.9477911646586, Blast_Score=162, Evalue=5e-40, Organism=Caenorhabditis elegans, GI133931034, Length=243, Percent_Identity=39.5061728395062, Blast_Score=159, Evalue=3e-39, Organism=Caenorhabditis elegans, GI193206114, Length=243, Percent_Identity=39.5061728395062, Blast_Score=159, Evalue=3e-39, Organism=Caenorhabditis elegans, GI193206116, Length=243, Percent_Identity=39.5061728395062, Blast_Score=159, Evalue=4e-39, Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=38.6666666666667, Blast_Score=156, Evalue=4e-38, Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=46.0606060606061, Blast_Score=152, Evalue=6e-37, Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=46.0606060606061, Blast_Score=152, Evalue=6e-37, Organism=Caenorhabditis elegans, GI25146157, Length=259, Percent_Identity=38.2239382239382, Blast_Score=144, Evalue=2e-34, Organism=Caenorhabditis elegans, GI133901658, Length=212, Percent_Identity=40.5660377358491, Blast_Score=142, Evalue=6e-34, Organism=Caenorhabditis elegans, GI133901662, Length=212, Percent_Identity=40.5660377358491, Blast_Score=142, Evalue=6e-34, Organism=Caenorhabditis elegans, GI17562804, Length=230, Percent_Identity=36.9565217391304, Blast_Score=140, Evalue=2e-33, Organism=Caenorhabditis elegans, GI86561515, Length=242, Percent_Identity=34.7107438016529, Blast_Score=132, Evalue=6e-31, Organism=Caenorhabditis elegans, GI17508421, Length=241, Percent_Identity=37.7593360995851, Blast_Score=130, Evalue=2e-30, Organism=Caenorhabditis elegans, GI32563584, Length=241, Percent_Identity=37.7593360995851, Blast_Score=130, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17541226, Length=261, Percent_Identity=34.0996168582375, Blast_Score=121, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17541224, Length=261, Percent_Identity=34.0996168582375, Blast_Score=121, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17560432, Length=226, Percent_Identity=36.7256637168142, Blast_Score=119, Evalue=6e-27, Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=29.7979797979798, Blast_Score=76, Evalue=7e-14, Organism=Saccharomyces cerevisiae, GI6325281, Length=495, Percent_Identity=46.8686868686869, Blast_Score=462, Evalue=1e-131, Organism=Saccharomyces cerevisiae, GI6323736, Length=505, Percent_Identity=46.3366336633663, Blast_Score=442, Evalue=1e-125, Organism=Saccharomyces cerevisiae, GI6320854, Length=519, Percent_Identity=45.0867052023121, Blast_Score=438, Evalue=1e-123, Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=42.911877394636, Blast_Score=220, Evalue=6e-58, Organism=Saccharomyces cerevisiae, GI6320077, Length=260, Percent_Identity=42.6923076923077, Blast_Score=218, Evalue=2e-57, Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=41.3385826771654, Blast_Score=206, Evalue=6e-54, Organism=Saccharomyces cerevisiae, GI6324691, Length=237, Percent_Identity=43.0379746835443, Blast_Score=198, Evalue=2e-51, Organism=Saccharomyces cerevisiae, GI6324833, Length=253, Percent_Identity=41.897233201581, Blast_Score=196, Evalue=1e-50, Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=37.9591836734694, Blast_Score=190, Evalue=7e-49, Organism=Saccharomyces cerevisiae, GI6320602, Length=243, Percent_Identity=42.798353909465, Blast_Score=188, Evalue=2e-48, Organism=Saccharomyces cerevisiae, GI6322994, Length=230, Percent_Identity=38.695652173913, Blast_Score=173, Evalue=6e-44, Organism=Saccharomyces cerevisiae, GI6324000, Length=240, Percent_Identity=40.8333333333333, Blast_Score=172, Evalue=2e-43, Organism=Saccharomyces cerevisiae, GI6323429, Length=252, Percent_Identity=40.0793650793651, Blast_Score=171, Evalue=3e-43, Organism=Saccharomyces cerevisiae, GI6321709, Length=257, Percent_Identity=38.9105058365759, Blast_Score=167, Evalue=3e-42, Organism=Saccharomyces cerevisiae, GI6322651, Length=245, Percent_Identity=35.1020408163265, Blast_Score=162, Evalue=1e-40, Organism=Saccharomyces cerevisiae, GI6321465, Length=239, Percent_Identity=38.0753138075314, Blast_Score=142, Evalue=2e-34, Organism=Saccharomyces cerevisiae, GI6319554, Length=213, Percent_Identity=38.9671361502347, Blast_Score=139, Evalue=1e-33, Organism=Saccharomyces cerevisiae, GI6325431, Length=226, Percent_Identity=37.6106194690265, Blast_Score=134, Evalue=3e-32, Organism=Saccharomyces cerevisiae, GI6325183, Length=237, Percent_Identity=34.1772151898734, Blast_Score=129, Evalue=2e-30, Organism=Saccharomyces cerevisiae, GI6320887, Length=249, Percent_Identity=32.5301204819277, Blast_Score=118, Evalue=3e-27, Organism=Saccharomyces cerevisiae, GI6320583, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24658770, Length=449, Percent_Identity=47.8841870824053, Blast_Score=433, Evalue=1e-121, Organism=Drosophila melanogaster, GI28574878, Length=519, Percent_Identity=42.9672447013487, Blast_Score=424, Evalue=1e-118, Organism=Drosophila melanogaster, GI24665814, Length=517, Percent_Identity=42.9400386847195, Blast_Score=424, Evalue=1e-118, Organism=Drosophila melanogaster, GI24639391, Length=450, Percent_Identity=44, Blast_Score=387, Evalue=1e-107, Organism=Drosophila melanogaster, GI161076486, Length=310, Percent_Identity=37.741935483871, Blast_Score=223, Evalue=4e-58, Organism=Drosophila melanogaster, GI17137560, Length=310, Percent_Identity=37.741935483871, Blast_Score=223, Evalue=5e-58, Organism=Drosophila melanogaster, GI161076488, Length=310, Percent_Identity=37.741935483871, Blast_Score=222, Evalue=7e-58, Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=43.7007874015748, Blast_Score=220, Evalue=3e-57, Organism=Drosophila melanogaster, GI19920408, Length=262, Percent_Identity=41.9847328244275, Blast_Score=209, Evalue=5e-54, Organism=Drosophila melanogaster, GI24651451, Length=262, Percent_Identity=42.7480916030534, Blast_Score=208, Evalue=1e-53, Organism=Drosophila melanogaster, GI45554047, Length=163, Percent_Identity=58.2822085889571, Blast_Score=207, Evalue=2e-53, Organism=Drosophila melanogaster, GI24649446, Length=254, Percent_Identity=40.1574803149606, Blast_Score=202, Evalue=5e-52, Organism=Drosophila melanogaster, GI24660075, Length=230, Percent_Identity=43.4782608695652, Blast_Score=199, Evalue=7e-51, Organism=Drosophila melanogaster, GI281365776, Length=230, Percent_Identity=43.4782608695652, Blast_Score=199, Evalue=7e-51, Organism=Drosophila melanogaster, GI45552965, Length=230, Percent_Identity=43.4782608695652, Blast_Score=198, Evalue=9e-51, Organism=Drosophila melanogaster, GI24652279, Length=272, Percent_Identity=37.8676470588235, Blast_Score=198, Evalue=1e-50, Organism=Drosophila melanogaster, GI24640100, Length=253, Percent_Identity=41.1067193675889, Blast_Score=197, Evalue=1e-50, Organism=Drosophila melanogaster, GI19921202, Length=243, Percent_Identity=41.1522633744856, Blast_Score=196, Evalue=5e-50, Organism=Drosophila melanogaster, GI24663015, Length=253, Percent_Identity=41.501976284585, Blast_Score=192, Evalue=5e-49, Organism=Drosophila melanogaster, GI17738151, Length=242, Percent_Identity=41.3223140495868, Blast_Score=191, Evalue=1e-48, Organism=Drosophila melanogaster, GI18860063, Length=240, Percent_Identity=41.6666666666667, Blast_Score=191, Evalue=1e-48, Organism=Drosophila melanogaster, GI281361487, Length=253, Percent_Identity=40.3162055335968, Blast_Score=189, Evalue=6e-48, Organism=Drosophila melanogaster, GI24656825, Length=227, Percent_Identity=41.4096916299559, Blast_Score=171, Evalue=1e-42, Organism=Drosophila melanogaster, GI24656820, Length=227, Percent_Identity=41.4096916299559, Blast_Score=171, Evalue=1e-42, Organism=Drosophila melanogaster, GI281363136, Length=235, Percent_Identity=39.1489361702128, Blast_Score=160, Evalue=2e-39, Organism=Drosophila melanogaster, GI78707192, Length=235, Percent_Identity=39.1489361702128, Blast_Score=160, Evalue=2e-39, Organism=Drosophila melanogaster, GI21355121, Length=235, Percent_Identity=36.5957446808511, Blast_Score=154, Evalue=3e-37, Organism=Drosophila melanogaster, GI24644145, Length=233, Percent_Identity=38.6266094420601, Blast_Score=150, Evalue=2e-36, Organism=Drosophila melanogaster, GI281360136, Length=228, Percent_Identity=38.1578947368421, Blast_Score=149, Evalue=7e-36, Organism=Drosophila melanogaster, GI24644411, Length=228, Percent_Identity=38.1578947368421, Blast_Score=149, Evalue=7e-36, Organism=Drosophila melanogaster, GI281360144, Length=228, Percent_Identity=38.1578947368421, Blast_Score=149, Evalue=7e-36, Organism=Drosophila melanogaster, GI281360140, Length=228, Percent_Identity=38.1578947368421, Blast_Score=149, Evalue=7e-36, Organism=Drosophila melanogaster, GI281360142, Length=230, Percent_Identity=38.695652173913, Blast_Score=148, Evalue=1e-35, Organism=Drosophila melanogaster, GI21357333, Length=230, Percent_Identity=38.695652173913, Blast_Score=148, Evalue=1e-35, Organism=Drosophila melanogaster, GI281360146, Length=230, Percent_Identity=38.695652173913, Blast_Score=148, Evalue=1e-35, Organism=Drosophila melanogaster, GI281360138, Length=230, Percent_Identity=38.695652173913, Blast_Score=148, Evalue=1e-35, Organism=Drosophila melanogaster, GI20129529, Length=274, Percent_Identity=35.036496350365, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI18859657, Length=251, Percent_Identity=38.2470119521912, Blast_Score=142, Evalue=9e-34, Organism=Drosophila melanogaster, GI24581396, Length=232, Percent_Identity=39.2241379310345, Blast_Score=139, Evalue=7e-33, Organism=Drosophila melanogaster, GI17864540, Length=214, Percent_Identity=41.1214953271028, Blast_Score=139, Evalue=9e-33, Organism=Drosophila melanogaster, GI28573010, Length=214, Percent_Identity=41.1214953271028, Blast_Score=139, Evalue=9e-33, Organism=Drosophila melanogaster, GI28571849, Length=236, Percent_Identity=39.4067796610169, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI28571847, Length=236, Percent_Identity=39.4067796610169, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI20129423, Length=233, Percent_Identity=35.1931330472103, Blast_Score=132, Evalue=6e-31, Organism=Drosophila melanogaster, GI24639486, Length=196, Percent_Identity=35.2040816326531, Blast_Score=106, Evalue=6e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR005936 - InterPro: IPR011546 - InterPro: IPR000642 [H]
Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]
EC number: 3.4.24.-
Molecular weight: Translated: 70782; Mature: 70651
Theoretical pI: Translated: 6.13; Mature: 6.13
Prosite motif: PS00674 AAA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQDQVREARINGREINVTK CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHCHHHHHHHHCCCCEEEEEE KDSNRYTTYIPVNDPKLLDNLLTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFM CCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH RQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEAKEEVGELVEYLREPSRFQKL HHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHH GGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQA CCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHH KKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRP HHCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC DVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGAD CCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHH LANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRSMVMTEAQKESTAYHEAGHAI HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH IGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIY HHHHCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC GPEHVSTGASNDIKVATNLARNMVTQWGFSDKLGPLLYAEEEGEVFLGRSVAKAKHMSDE CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEECHHHHHHHHCCHH TARIIDQEVKSLIERNYGRARQLLNDNMDILHAMKDALMKYETIDAPQIDDLMARREVRP HHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC PAGWEEPGSSNNSDNNGTPRAPRPVDEPRTPNPGNTMSEQLGDK CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC >Mature Secondary Structure AKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQDQVREARINGREINVTK CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHCHHHHHHHHCCCCEEEEEE KDSNRYTTYIPVNDPKLLDNLLTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFM CCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH RQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEAKEEVGELVEYLREPSRFQKL HHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHH GGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQA CCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHH KKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRP HHCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC DVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGAD CCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHH LANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRSMVMTEAQKESTAYHEAGHAI HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH IGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIY HHHHCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC GPEHVSTGASNDIKVATNLARNMVTQWGFSDKLGPLLYAEEEGEVFLGRSVAKAKHMSDE CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEECHHHHHHHHCCHH TARIIDQEVKSLIERNYGRARQLLNDNMDILHAMKDALMKYETIDAPQIDDLMARREVRP HHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC PAGWEEPGSSNNSDNNGTPRAPRPVDEPRTPNPGNTMSEQLGDK CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]