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The map label for this gene is uxaC [H]

Identifier: 238896617

GI number: 238896617

Start: 4599946

End: 4601358

Strand: Reverse

Name: uxaC [H]

Synonym: KP1_4818

Alternate gene names: 238896617

Gene position: 4601358-4599946 (Counterclockwise)

Preceding gene: 238896629

Following gene: 238896616

Centisome position: 87.67

GC content: 55.63

Gene sequence:

>1413_bases
ATGACATCGTTTATGACTGAAGATTTTCTACTTGATACCGAGTTTGCCCGCCGTCTGTACCATGATTACGCCAAAGATCA
GCCGATTTTCGACTACCACTGCCACCTTCCGCCGCAGCAGGTTGCCGAAAACTATCGCTTTAAAAACCTGTATGACATCT
GGCTGAAAGGCGATCACTATAAATGGCGCGCAATGCGCACTAACGGCGTGCCGGAGCGTCTGTGTACCGGTGATGCGTCC
GATCGCGAGAAATTTGACGCCTGGGCGGCCACGGTTCCGCACACTATTGGCAACCCGTTATACCACTGGACCCATTTAGA
GCTGCGTCGACCTTTTGGTATTACAGGTAAGCTGTTGTCGCCATCCACCGCCGATGAGATCTGGGACCAGTGTAATGATT
TGCTGGCTCAGGATGCCTTCTCCGCCCGCGGAATCATGAAACAGATGAATGTGAAGATGGTCGGTACCACCGACGATCCG
ATTGATTCTCTTGAGCACCACGCGGCTGTCGCCAAAGACAACTCCTTTGACATCAAAGTGCTGCCGAGCTGGCGCCCGGA
TAAAGCCTTCAACATCGAGTTGGCGACCTTCAATGATTATATGGCTAAGCTGGGCGAGGTATCCGATACCGATATTCGCC
GCTTCGCTGACCTGCAAAGCGCCCTGACCAAACGTCTGGATCATTTTGCCGCACACGGCTGCAAAGTCTCCGATCATGCG
CTGGACGTGGTGCTGTTTGCCGAAGCGACCGACGCCGAGCTGGATGACATTCTGGCGCGCCGCCTGGCTGGCGAGACCCT
TAGCGAACACGAAGTGGCGCAGTTCAAAACCGCGGTGCTGGTATTCCTCGGCGCAGAGTATGCCCGTCGCGGCTGGGTCC
AGCAGTACCACATTGGCGCGCTGCGTAACAACAACCTCCGTCAGTTCAAACTGTTAGGGCCAGACGTCGGCTTCGACTCG
ATCAACGATCGTCCGATGGCGGAAGAGCTGTCTAAGCTGCTGAGCAAGCAGAACGAAGAAAACCTGCTGCCGAAAACGAT
TCTCTACTGCCTGAACCCGCGTGATAACGAAGTGCTGGGCACCATGATCGGTAACTTCCAGGGTGAAGGCATGCCAGGCA
AGATGCAGTTCGGCTCCGGCTGGTGGTTCAACGATCAGAAAGACGGTATGGAGCGGCAGATGACCCAGCTGGCGCAGCTC
GGGCTGCTGAGCCGCTTCGTCGGGATGTTGACCGACAGTCGCAGCTTCCTCTCCTACACGCGCCACGAATACTTCCGCCG
CATTCTGTGCCAGATGATCGGCCGTTGGGTGGCTGCCGGCGAAGCGCCTGCGGATATCGCGCTGCTGGGCGAGATGGTGA
AAAACATTTGCTTTAACAATGCGCGTGACTATTTCGCCATTGAACTGAACTAA

Upstream 100 bases:

>100_bases
CGAAAAACAGTTCGGTCTGTAGAAATTGGTGTGATAACTTTGTCAGCATTGTAGTCAATCATCTGAAAGGCTCCCGCACT
GGAGCGAAGAGGACACGCGA

Downstream 100 bases:

>100_bases
GGCCAGAGGTCGGTTGATATGCAATACATCAAAATCCATTCGCAGGATAACGTCGCGGTCGCGCTGACGGATATCGCTGC
CGGTAGCGTGGTGACGATTG

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTSFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQVAENYRFKNLYDIWLKGDHYKWRAMRTNGVPERLCTGDAS
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWDQCNDLLAQDAFSARGIMKQMNVKMVGTTDDP
IDSLEHHAAVAKDNSFDIKVLPSWRPDKAFNIELATFNDYMAKLGEVSDTDIRRFADLQSALTKRLDHFAAHGCKVSDHA
LDVVLFAEATDAELDDILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDS
INDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVAAGEAPADIALLGEMVKNICFNNARDYFAIELN

Sequences:

>Translated_470_residues
MTSFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQVAENYRFKNLYDIWLKGDHYKWRAMRTNGVPERLCTGDAS
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWDQCNDLLAQDAFSARGIMKQMNVKMVGTTDDP
IDSLEHHAAVAKDNSFDIKVLPSWRPDKAFNIELATFNDYMAKLGEVSDTDIRRFADLQSALTKRLDHFAAHGCKVSDHA
LDVVLFAEATDAELDDILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDS
INDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVAAGEAPADIALLGEMVKNICFNNARDYFAIELN
>Mature_469_residues
TSFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQVAENYRFKNLYDIWLKGDHYKWRAMRTNGVPERLCTGDASD
REKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWDQCNDLLAQDAFSARGIMKQMNVKMVGTTDDPI
DSLEHHAAVAKDNSFDIKVLPSWRPDKAFNIELATFNDYMAKLGEVSDTDIRRFADLQSALTKRLDHFAAHGCKVSDHAL
DVVLFAEATDAELDDILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSI
NDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLG
LLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVAAGEAPADIALLGEMVKNICFNNARDYFAIELN

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=470, Percent_Identity=95.531914893617, Blast_Score=948, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53784; Mature: 53652

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQVAENYRFKNLYDIWLKGDHY
CCCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCEEEEEEECCCE
KWRAMRTNGVPERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLS
EEEEEECCCCCHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PSTADEIWDQCNDLLAQDAFSARGIMKQMNVKMVGTTDDPIDSLEHHAAVAKDNSFDIKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEE
LPSWRPDKAFNIELATFNDYMAKLGEVSDTDIRRFADLQSALTKRLDHFAAHGCKVSDHA
CCCCCCCCEEEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LDVVLFAEATDAELDDILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGA
EEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLG
HCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCHHHH
TMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYT
HHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGRWVAAGEAPADIALLGEMVKNICFNNARDYFAIELN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure 
TSFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQVAENYRFKNLYDIWLKGDHY
CCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCEEEEEEECCCE
KWRAMRTNGVPERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLS
EEEEEECCCCCHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PSTADEIWDQCNDLLAQDAFSARGIMKQMNVKMVGTTDDPIDSLEHHAAVAKDNSFDIKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEE
LPSWRPDKAFNIELATFNDYMAKLGEVSDTDIRRFADLQSALTKRLDHFAAHGCKVSDHA
CCCCCCCCEEEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LDVVLFAEATDAELDDILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGA
EEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLG
HCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCHHHH
TMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYT
HHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGRWVAAGEAPADIALLGEMVKNICFNNARDYFAIELN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA