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The map label for this gene is dhaR [H]

Identifier: 238896588

GI number: 238896588

Start: 4567967

End: 4569892

Strand: Reverse

Name: dhaR [H]

Synonym: KP1_4789

Alternate gene names: 238896588

Gene position: 4569892-4567967 (Counterclockwise)

Preceding gene: 238896589

Following gene: 238896583

Centisome position: 87.07

GC content: 60.96

Gene sequence:

>1926_bases
ATGACTGTTCAGACTCAGGATACCGGGAAGGCGGTCTCTTCCGTCATTGCCCAGTCATGGCACCGCTGCAGCAAGTTTAT
GCAGCGCGAAACCTGGCAAACGCCGCACCAGGCCCAGGGCCTGACCTTCGACTCCATCTGTCGGCGTAAAACCGCGCTGC
TGACCATCGGCCAGGCGGCGCTGGAAGACGCCTGGGAGTTTATGGACGGCCGCCCCTGCGCGCTGTTTATTCTTGATGAG
TCCGCCTGCATCCTGAGCCGTTGCGGCGAGCCGCAAACCCTGGCCCAGCTGGCTGCCCTGGGATTTCGCGACGGCAGCTA
TTGTGCGGAGAGCATTATCGGCACCTGCGCGCTGTCGCTGGCCGCGATGCAGGGCCAGCCGATCAACACCGCCGGCGATC
GGCATTTTAAGCAGGCGCTACAGCCATGGAGTTTTTGCTCGACGCCGGTGTTTGATAACCACGGGCGGCTGTTCGGCTCT
ATCTCGCTTTGCTGTCTGGTCGAGCACCAGTCCAGCGCCGACCTCTCCCTGACGCTGGCCATCGCCCGCGAGGTGGGTAA
CTCCCTGCTCACCGACAGCCTGCTGGCGGAATCCAACCGCCACCTCAATCAGATGTACGGCCTGCTGGAGAGCATGGACG
ATGGGGTGATGGCGTGGAACGAACAGGGCGTGCTGCAGTTTCTCAATGTTCAGGCGGCGAGACTGCTGCATCTTGATGCT
CAGGCCAGCCAGGGGAAAAATATCGCCGATCTGGTGACCCTCCCGGCGCTGCTGCGCCGCGCCATCAAACACGCCCGCGG
CCTGAATCACGTCGAAGTCACCTTTGAAAGTCAGCATCAGTTTGTCGACGCGGTGATCACCTTAAAACCGATTGTCGAGG
CGCAAGGCAACAGTTTTATTCTGCTGCTGCACCCGGTGGAGCAGATGCGGCAGTTGATGACCAGCCAGCTCGGTAAAGTC
AGCCACACCTTTGAGCAGATGTCTGCCGACGATCCGGAAACCCGACGCCTGATCCACTTTGGCCGCCAGGCGGCGCGCGG
CGGCTTCCCGGTGCTACTGTGCGGCGAAGAGGGGGTCGGGAAAGAGCTGCTGAGCCAGGCTATTCACAATGAAAGCGAAC
GGGCGGGCGGCCCCTACATCGCCGTCAACTGCCAGCTATATGCCGACAGCGTGCTGGGCCAGGACTTTATGGGCAGCGCC
CCTACCGACGATGAAAATGGTCGCCTGAGCCGCCTTGAGCTGGCCAACGGCGGCACCCTGTTTCTGGAAAAGATCGAGTA
TCTGGCGCCGGAGCTGCAGTCGGCTCTGCTGCAGGTGATTAAGCAGGGCGTGCTCACCCGCCTCGACGCCCGGCGCCTGA
TCCCGGTGGATGTGAAGGTGATTGCCACCACCACCGTCGATCTGGCCAATCTGGTGGAACAGAACCGCTTTAGCCGCCAG
CTGTACTATGCGCTGCACTCCTTTGAGATCGTCATCCCGCCGCTGCGCGCCCGACGCAACAGTATTCCGTCGCTGGTGCA
TAACCGGTTGAAGAGCCTGGAGAAGCGTTTCTCTTCGCGACTGAAAGTGGACGATGACGCGCTGGCGCAGCTGGTGGCCT
ACTCGTGGCCGGGGAATGATTTTGAGCTCAATAGCGTCATTGAGAATATCGCCATCAGCAGCGACAACGGCCACATTCGC
CTGAGTAATCTGCCGGAATATCTCTTTTCCGAGCGGCCGGGCGGGGATAGCGCGTCATCGCTGCTGCCGGCCAGCCTGAC
TTTTAGCGCCATCGAAAAGGAAGCTATTATTCACGCCGCCCGGGTGACCAGCGGGCGGGTGCAGGAGATGTCGCAGCTGC
TCAATATCGGCCGCACCACCCTGTGGCGCAAAATGAAGCAGTACGATATTGACGCCAGCCAGTTCAAGCGCAAGCATCAG
GCCTAG

Upstream 100 bases:

>100_bases
TCGCGGTGGCTAAACCGCTGGCCCAGGTCAGCGGTTTTTCTTTCTCCCCTCCGGCAGTCGCTGCCGGAGGGGTTCTCTAT
GGTACAACGCGGAAAAGGAT

Downstream 100 bases:

>100_bases
TCTCTTCGATTCGCGCCATGGAGAACAGGGCATCCGACAGGCGATTGCTGTAGCGTTTGAGCGCGTCGCGCAGCGGATGC
GCGCGGTCCATGGCCGTCAG

Product: DNA-binding transcriptional regulator DhaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MTVQTQDTGKAVSSVIAQSWHRCSKFMQRETWQTPHQAQGLTFDSICRRKTALLTIGQAALEDAWEFMDGRPCALFILDE
SACILSRCGEPQTLAQLAALGFRDGSYCAESIIGTCALSLAAMQGQPINTAGDRHFKQALQPWSFCSTPVFDNHGRLFGS
ISLCCLVEHQSSADLSLTLAIAREVGNSLLTDSLLAESNRHLNQMYGLLESMDDGVMAWNEQGVLQFLNVQAARLLHLDA
QASQGKNIADLVTLPALLRRAIKHARGLNHVEVTFESQHQFVDAVITLKPIVEAQGNSFILLLHPVEQMRQLMTSQLGKV
SHTFEQMSADDPETRRLIHFGRQAARGGFPVLLCGEEGVGKELLSQAIHNESERAGGPYIAVNCQLYADSVLGQDFMGSA
PTDDENGRLSRLELANGGTLFLEKIEYLAPELQSALLQVIKQGVLTRLDARRLIPVDVKVIATTTVDLANLVEQNRFSRQ
LYYALHSFEIVIPPLRARRNSIPSLVHNRLKSLEKRFSSRLKVDDDALAQLVAYSWPGNDFELNSVIENIAISSDNGHIR
LSNLPEYLFSERPGGDSASSLLPASLTFSAIEKEAIIHAARVTSGRVQEMSQLLNIGRTTLWRKMKQYDIDASQFKRKHQ
A

Sequences:

>Translated_641_residues
MTVQTQDTGKAVSSVIAQSWHRCSKFMQRETWQTPHQAQGLTFDSICRRKTALLTIGQAALEDAWEFMDGRPCALFILDE
SACILSRCGEPQTLAQLAALGFRDGSYCAESIIGTCALSLAAMQGQPINTAGDRHFKQALQPWSFCSTPVFDNHGRLFGS
ISLCCLVEHQSSADLSLTLAIAREVGNSLLTDSLLAESNRHLNQMYGLLESMDDGVMAWNEQGVLQFLNVQAARLLHLDA
QASQGKNIADLVTLPALLRRAIKHARGLNHVEVTFESQHQFVDAVITLKPIVEAQGNSFILLLHPVEQMRQLMTSQLGKV
SHTFEQMSADDPETRRLIHFGRQAARGGFPVLLCGEEGVGKELLSQAIHNESERAGGPYIAVNCQLYADSVLGQDFMGSA
PTDDENGRLSRLELANGGTLFLEKIEYLAPELQSALLQVIKQGVLTRLDARRLIPVDVKVIATTTVDLANLVEQNRFSRQ
LYYALHSFEIVIPPLRARRNSIPSLVHNRLKSLEKRFSSRLKVDDDALAQLVAYSWPGNDFELNSVIENIAISSDNGHIR
LSNLPEYLFSERPGGDSASSLLPASLTFSAIEKEAIIHAARVTSGRVQEMSQLLNIGRTTLWRKMKQYDIDASQFKRKHQ
A
>Mature_640_residues
TVQTQDTGKAVSSVIAQSWHRCSKFMQRETWQTPHQAQGLTFDSICRRKTALLTIGQAALEDAWEFMDGRPCALFILDES
ACILSRCGEPQTLAQLAALGFRDGSYCAESIIGTCALSLAAMQGQPINTAGDRHFKQALQPWSFCSTPVFDNHGRLFGSI
SLCCLVEHQSSADLSLTLAIAREVGNSLLTDSLLAESNRHLNQMYGLLESMDDGVMAWNEQGVLQFLNVQAARLLHLDAQ
ASQGKNIADLVTLPALLRRAIKHARGLNHVEVTFESQHQFVDAVITLKPIVEAQGNSFILLLHPVEQMRQLMTSQLGKVS
HTFEQMSADDPETRRLIHFGRQAARGGFPVLLCGEEGVGKELLSQAIHNESERAGGPYIAVNCQLYADSVLGQDFMGSAP
TDDENGRLSRLELANGGTLFLEKIEYLAPELQSALLQVIKQGVLTRLDARRLIPVDVKVIATTTVDLANLVEQNRFSRQL
YYALHSFEIVIPPLRARRNSIPSLVHNRLKSLEKRFSSRLKVDDDALAQLVAYSWPGNDFELNSVIENIAISSDNGHIRL
SNLPEYLFSERPGGDSASSLLPASLTFSAIEKEAIIHAARVTSGRVQEMSQLLNIGRTTLWRKMKQYDIDASQFKRKHQA

Specific function: Transcriptional activator of the glycerol utilization dha operon [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87081858, Length=638, Percent_Identity=73.6677115987461, Blast_Score=988, Evalue=0.0,
Organism=Escherichia coli, GI87082117, Length=305, Percent_Identity=34.7540983606557, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1788550, Length=298, Percent_Identity=32.5503355704698, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1789087, Length=332, Percent_Identity=31.6265060240964, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1790437, Length=281, Percent_Identity=33.8078291814947, Blast_Score=142, Evalue=9e-35,
Organism=Escherichia coli, GI1790299, Length=313, Percent_Identity=29.7124600638978, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789233, Length=530, Percent_Identity=26.2264150943396, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786524, Length=302, Percent_Identity=34.4370860927152, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788905, Length=321, Percent_Identity=29.595015576324, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1787583, Length=340, Percent_Identity=27.3529411764706, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87082152, Length=206, Percent_Identity=35.9223300970874, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=31.1965811965812, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1789828, Length=248, Percent_Identity=28.6290322580645, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70944; Mature: 70813

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQTQDTGKAVSSVIAQSWHRCSKFMQRETWQTPHQAQGLTFDSICRRKTALLTIGQAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LEDAWEFMDGRPCALFILDESACILSRCGEPQTLAQLAALGFRDGSYCAESIIGTCALSL
HHHHHHHHCCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAMQGQPINTAGDRHFKQALQPWSFCSTPVFDNHGRLFGSISLCCLVEHQSSADLSLTLA
HHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEECEEEEEEEECCCCCCCEEHHH
IAREVGNSLLTDSLLAESNRHLNQMYGLLESMDDGVMAWNEQGVLQFLNVQAARLLHLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHEECC
QASQGKNIADLVTLPALLRRAIKHARGLNHVEVTFESQHQFVDAVITLKPIVEAQGNSFI
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEE
LLLHPVEQMRQLMTSQLGKVSHTFEQMSADDPETRRLIHFGRQAARGGFPVLLCGEEGVG
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KELLSQAIHNESERAGGPYIAVNCQLYADSVLGQDFMGSAPTDDENGRLSRLELANGGTL
HHHHHHHHCCCCHHCCCCEEEEEEEEEHHHHHCCHHCCCCCCCCCCCCEEEEEECCCCHH
FLEKIEYLAPELQSALLQVIKQGVLTRLDARRLIPVDVKVIATTTVDLANLVEQNRFSRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
LYYALHSFEIVIPPLRARRNSIPSLVHNRLKSLEKRFSSRLKVDDDALAQLVAYSWPGND
HHHHHHHCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
FELNSVIENIAISSDNGHIRLSNLPEYLFSERPGGDSASSLLPASLTFSAIEKEAIIHAA
EEHHHHHHHHEEECCCCEEEECCCHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHH
RVTSGRVQEMSQLLNIGRTTLWRKMKQYDIDASQFKRKHQA
HHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure 
TVQTQDTGKAVSSVIAQSWHRCSKFMQRETWQTPHQAQGLTFDSICRRKTALLTIGQAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LEDAWEFMDGRPCALFILDESACILSRCGEPQTLAQLAALGFRDGSYCAESIIGTCALSL
HHHHHHHHCCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAMQGQPINTAGDRHFKQALQPWSFCSTPVFDNHGRLFGSISLCCLVEHQSSADLSLTLA
HHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEECEEEEEEEECCCCCCCEEHHH
IAREVGNSLLTDSLLAESNRHLNQMYGLLESMDDGVMAWNEQGVLQFLNVQAARLLHLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHEECC
QASQGKNIADLVTLPALLRRAIKHARGLNHVEVTFESQHQFVDAVITLKPIVEAQGNSFI
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEE
LLLHPVEQMRQLMTSQLGKVSHTFEQMSADDPETRRLIHFGRQAARGGFPVLLCGEEGVG
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KELLSQAIHNESERAGGPYIAVNCQLYADSVLGQDFMGSAPTDDENGRLSRLELANGGTL
HHHHHHHHCCCCHHCCCCEEEEEEEEEHHHHHCCHHCCCCCCCCCCCCEEEEEECCCCHH
FLEKIEYLAPELQSALLQVIKQGVLTRLDARRLIPVDVKVIATTTVDLANLVEQNRFSRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
LYYALHSFEIVIPPLRARRNSIPSLVHNRLKSLEKRFSSRLKVDDDALAQLVAYSWPGND
HHHHHHHCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
FELNSVIENIAISSDNGHIRLSNLPEYLFSERPGGDSASSLLPASLTFSAIEKEAIIHAA
EEHHHHHHHHEEECCCCEEEECCCHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHH
RVTSGRVQEMSQLLNIGRTTLWRKMKQYDIDASQFKRKHQA
HHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA