Click here to switch to the map view.

The map label for this gene is yfiN [H]

Identifier: 238896048

GI number: 238896048

Start: 4017240

End: 4018463

Strand: Direct

Name: yfiN [H]

Synonym: KP1_4180

Alternate gene names: 238896048

Gene position: 4017240-4018463 (Clockwise)

Preceding gene: 238896047

Following gene: 238896049

Centisome position: 76.54

GC content: 58.09

Gene sequence:

>1224_bases
ATGAATAAGGACTTTTCACAGACTCCGCGCCCGACTTTCAAACGCGCGCTCCGTCGCATTAGCGTGATAAGCGTGGTGAT
CTCCATGACGCTGGTCTGGCTGCTGCTGAGTACAGCCTCAATCTTCACGCTCAAGCAGTACGCGCAGAAAAATCTTGAGC
TCACTGCCGCGACCATGGGGCGCAGCCTCGAAGCCGCCCTGGTGTTTGGCGACAGCGCGGCGGCAGAGGAGACCCTCGCG
TCGTTGGGCAAGCAAGGGCAGATCTCCCAGGCAATCGTGCTAAACGGCCAGATGCAGCACTTCGCCGCGTGGCGCCATGA
ACCGCTGGCCAATAAAGAGCAAGTGAGCGGGCTTATCAGTAAATGGCTGTTTCCGGAGCCCACGGTGCAGCCCATCTGGC
ACCAGGGCAAACAAATCGGCGAGCTGAGATTGACCGCGCTTGATGAACTGATTAGCCACTTTCTCGGTATCTCGATTCTG
GTGCTGACCGGCAGCATTCTGCTCGCCTCGTTCATCGCCCTGCTGCTGACCCACTCCCTACACCGGGGGATCGTCGCCGC
CCTGCAGAGCATCACTGAGGTCGTGCATGATATACGTGAAAACCGCCACTTCTCCCGGCGGGTGCCGGAGGAGCGTATCG
AGGAGTTCCATCTTTTCGCCCAGGACTTTAACAGCCTGCTGGGGGAAATGGAGGACTGGCAGCGCCAGCTGCAGGCCAAA
AACGCGCAGCTGTTGCGCAGTTCGTTACACGATCCGTTGACCGGCCTGGCTAACCGCGCCGCCTTTCGTAACGCGCTCGC
CGAGCTGATGCAGAATGAAGTCGATCATCAAACCTCGGCATTGCTGTTTCTTGATGGCGATAATTTCAAACTGATTAACG
ACAACTGGGGGCATGCGGCGGGCGATAAAGTGCTGATGGAGGTCGCCAGCCGCCTGATGACTTTTGCCGGTAAACGCCAT
CTGGCGTGGCGTCTTGGCGGCGATGAGTTTGCCGTTCTGCTGCGCGAGGTGCGCTCGGAAGCAGAAGTGCAGGCCCTGTG
CCAGGCGCTAACGGAACAATTTCTTCCGCCATTCAACCTGCACAACGGTCATAGCGCCACGCTCTCGCTGAGCGTCGGTT
ATGCCCTGGCGTGGGAGCACGCCACCGCGGAATCACTGCAAGAACTTGCCGATCAGAATATGTATCGGATGAAAAACCAA
CGTATCCAGCAGACGCTGAAATAA

Upstream 100 bases:

>100_bases
AATGACGACCGGGTCCGCTTCTCCGTTAATCTGGACGTTCTGACGCACAGCGGGGTTCGGGTTAACCCGGACGTCCTGAT
GCTTGCCCGGAAGAAACCAC

Downstream 100 bases:

>100_bases
TAAAGGACTCATTATGATCAGAAAATATTTCGTCCCCGCCCTGATGGCGGCGGCGCTTTTGACAGGTTGCCAGGCTCCTC
AGGGAAAATTTACCCCCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNKDFSQTPRPTFKRALRRISVISVVISMTLVWLLLSTASIFTLKQYAQKNLELTAATMGRSLEAALVFGDSAAAEETLA
SLGKQGQISQAIVLNGQMQHFAAWRHEPLANKEQVSGLISKWLFPEPTVQPIWHQGKQIGELRLTALDELISHFLGISIL
VLTGSILLASFIALLLTHSLHRGIVAALQSITEVVHDIRENRHFSRRVPEERIEEFHLFAQDFNSLLGEMEDWQRQLQAK
NAQLLRSSLHDPLTGLANRAAFRNALAELMQNEVDHQTSALLFLDGDNFKLINDNWGHAAGDKVLMEVASRLMTFAGKRH
LAWRLGGDEFAVLLREVRSEAEVQALCQALTEQFLPPFNLHNGHSATLSLSVGYALAWEHATAESLQELADQNMYRMKNQ
RIQQTLK

Sequences:

>Translated_407_residues
MNKDFSQTPRPTFKRALRRISVISVVISMTLVWLLLSTASIFTLKQYAQKNLELTAATMGRSLEAALVFGDSAAAEETLA
SLGKQGQISQAIVLNGQMQHFAAWRHEPLANKEQVSGLISKWLFPEPTVQPIWHQGKQIGELRLTALDELISHFLGISIL
VLTGSILLASFIALLLTHSLHRGIVAALQSITEVVHDIRENRHFSRRVPEERIEEFHLFAQDFNSLLGEMEDWQRQLQAK
NAQLLRSSLHDPLTGLANRAAFRNALAELMQNEVDHQTSALLFLDGDNFKLINDNWGHAAGDKVLMEVASRLMTFAGKRH
LAWRLGGDEFAVLLREVRSEAEVQALCQALTEQFLPPFNLHNGHSATLSLSVGYALAWEHATAESLQELADQNMYRMKNQ
RIQQTLK
>Mature_407_residues
MNKDFSQTPRPTFKRALRRISVISVVISMTLVWLLLSTASIFTLKQYAQKNLELTAATMGRSLEAALVFGDSAAAEETLA
SLGKQGQISQAIVLNGQMQHFAAWRHEPLANKEQVSGLISKWLFPEPTVQPIWHQGKQIGELRLTALDELISHFLGISIL
VLTGSILLASFIALLLTHSLHRGIVAALQSITEVVHDIRENRHFSRRVPEERIEEFHLFAQDFNSLLGEMEDWQRQLQAK
NAQLLRSSLHDPLTGLANRAAFRNALAELMQNEVDHQTSALLFLDGDNFKLINDNWGHAAGDKVLMEVASRLMTFAGKRH
LAWRLGGDEFAVLLREVRSEAEVQALCQALTEQFLPPFNLHNGHSATLSLSVGYALAWEHATAESLQELADQNMYRMKNQ
RIQQTLK

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Escherichia coli, GI1788956, Length=407, Percent_Identity=62.6535626535627, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1788381, Length=100, Percent_Identity=47, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=34.3195266272189, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=30.3225806451613, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787541, Length=149, Percent_Identity=32.8859060402685, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=35.3293413173653, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787262, Length=152, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786584, Length=130, Percent_Identity=35.3846153846154, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787056, Length=165, Percent_Identity=34.5454545454545, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787802, Length=158, Percent_Identity=34.1772151898734, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=27.3885350318471, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=35.0574712643678, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 45693; Mature: 45693

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKDFSQTPRPTFKRALRRISVISVVISMTLVWLLLSTASIFTLKQYAQKNLELTAATMG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHC
RSLEAALVFGDSAAAEETLASLGKQGQISQAIVLNGQMQHFAAWRHEPLANKEQVSGLIS
CCHHHHEEECCHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHH
KWLFPEPTVQPIWHQGKQIGELRLTALDELISHFLGISILVLTGSILLASFIALLLTHSL
HHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRGIVAALQSITEVVHDIRENRHFSRRVPEERIEEFHLFAQDFNSLLGEMEDWQRQLQAK
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAQLLRSSLHDPLTGLANRAAFRNALAELMQNEVDHQTSALLFLDGDNFKLINDNWGHAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEEEEECCCEEEECCCCCCCH
GDKVLMEVASRLMTFAGKRHLAWRLGGDEFAVLLREVRSEAEVQALCQALTEQFLPPFNL
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HNGHSATLSLSVGYALAWEHATAESLQELADQNMYRMKNQRIQQTLK
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKDFSQTPRPTFKRALRRISVISVVISMTLVWLLLSTASIFTLKQYAQKNLELTAATMG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHC
RSLEAALVFGDSAAAEETLASLGKQGQISQAIVLNGQMQHFAAWRHEPLANKEQVSGLIS
CCHHHHEEECCHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHH
KWLFPEPTVQPIWHQGKQIGELRLTALDELISHFLGISILVLTGSILLASFIALLLTHSL
HHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRGIVAALQSITEVVHDIRENRHFSRRVPEERIEEFHLFAQDFNSLLGEMEDWQRQLQAK
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAQLLRSSLHDPLTGLANRAAFRNALAELMQNEVDHQTSALLFLDGDNFKLINDNWGHAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEEEEECCCEEEECCCCCCCH
GDKVLMEVASRLMTFAGKRHLAWRLGGDEFAVLLREVRSEAEVQALCQALTEQFLPPFNL
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HNGHSATLSLSVGYALAWEHATAESLQELADQNMYRMKNQRIQQTLK
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 6357787; 7567469 [H]