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The map label for this gene is clpX [H]

Identifier: 238893387

GI number: 238893387

Start: 1225848

End: 1227122

Strand: Direct

Name: clpX [H]

Synonym: KP1_1271

Alternate gene names: 238893387

Gene position: 1225848-1227122 (Clockwise)

Preceding gene: 238893386

Following gene: 238893388

Centisome position: 23.36

GC content: 56.16

Gene sequence:

>1275_bases
ATGACAGATAAACGCAAAGATGGATCGGGCAAATTGTTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGTAA
GCTGATCGCCGGGCCATCCGTGTATATCTGCGACGAATGCGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTGGCGCCGCACCGCGAGCGCAGCGCGCTGCCGACGCCGCACGAGATTCGCCACCACCTTGATGACTACGTCATCGGT
CAGGAACAGGCGAAGAAGGTGTTGGCGGTCGCGGTATACAACCACTACAAGCGTCTGCGCAATGGCGATACCAGCAATGG
CGTAGAGCTGGGTAAAAGCAACATCCTGCTGATCGGGCCGACCGGTTCCGGTAAAACGCTGCTGGCGGAAACGCTGGCGC
GCCTGCTGGATGTGCCGTTTACCATGGCGGACGCCACTACCCTGACCGAAGCCGGTTATGTGGGTGAGGACGTCGAAAAT
ATCATTCAGAAACTACTGCAGAAGTGCGATTACGACGTGCAGAAAGCGCAGCGCGGCATCGTTTATATCGACGAAATCGA
CAAAATTTCGCGTAAATCCGATAACCCGTCGATTACGCGCGACGTCTCAGGCGAAGGCGTGCAGCAGGCGCTGCTGAAGC
TTATCGAAGGGACCGTTGCCGCCGTTCCGCCGCAGGGCGGGCGTAAACATCCGCAGCAGGAGTTCCTGCAGGTTGATACC
TCCAAGATCCTGTTTATCTGCGGCGGCGCGTTCGCTGGCCTGGACAAAGTGATTTCCCACCGTGTGGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCGAGCGAAGGGGAACTGCTGGCTCAGGTCGAGCCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCGGAGTTCATCGGCCGTCTGCCGGTAGTGGCTACCCTGAACGAGCTGAGCGAAGAA
GCCCTGATCCAGATCCTGAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAGCCTTGAAGGCGCAGA
GCTCGAATTCCGCGACGAAGCGCTGGACGCTATCGCCAAGAAAGCGATGGCGCGTAAAACCGGCGCCCGTGGCCTGCGCT
CAATTGTGGAAGCGGCGCTGCTGGATACCATGTATGACCTGCCTTCGATGGAAGATGTCGAAAAAGTGGTCATTGATGAG
TCGGTTATCGCCGGTCAGAGCAAACCGCTGCTGATCTACGGCAAACCGGAAGCTCAGCAGGCATCTGGTGAATAA

Upstream 100 bases:

>100_bases
CTAATGAAGGGCGGCACAACGCTATATGGCGGCTTGCGCCTGAGAATGGCATTTGCGTCGTCGTGTGCGGCACAAAGAAC
TTAAAAAGAGGTTTGGACTC

Downstream 100 bases:

>100_bases
TTAACCATTTCACTCAAGCAGTTAACAAAAAGGGGGGATTTTATCTCCCCTTTTATTTTTCCTGCATTCCCGCCGTTGAA
TGTGTGGAATACATCCCCAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRHHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFSLEGAELEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIAGQSKPLLIYGKPEAQQASGE

Sequences:

>Translated_424_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRHHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFSLEGAELEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIAGQSKPLLIYGKPEAQQASGE
>Mature_423_residues
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRHHLDDYVIGQ
EQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENI
IQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTS
KILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEA
LIQILKEPKNALTKQYQALFSLEGAELEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDES
VIAGQSKPLLIYGKPEAQQASGE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=52.4390243902439, Blast_Score=311, Evalue=9e-85,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=98.8207547169811, Blast_Score=850, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=45, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=45.9807073954984, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=45.9807073954984, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=417, Percent_Identity=38.3693045563549, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=39.84375, Blast_Score=177, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=39.6713615023474, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=47.1875, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=47.1875, Blast_Score=288, Evalue=7e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46295; Mature: 46163

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRE
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC
RSALPTPHEIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGP
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCHHHHHHHCC
IPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFSLEGAELEFRDEALDAIAK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
ASGE
CCCC
>Mature Secondary Structure 
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRE
CCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC
RSALPTPHEIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGP
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCHHHHHHHCC
IPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFSLEGAELEFRDEALDAIAK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
ASGE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA