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The map label for this gene is secD [H]

Identifier: 238893344

GI number: 238893344

Start: 1185096

End: 1186943

Strand: Direct

Name: secD [H]

Synonym: KP1_1225

Alternate gene names: 238893344

Gene position: 1185096-1186943 (Clockwise)

Preceding gene: 238893343

Following gene: 238893345

Centisome position: 22.58

GC content: 57.63

Gene sequence:

>1848_bases
GTGTTAAACCGTTATCCTTTGTGGAAGTACGTCATGCTGGTCGTCGTCATTGTCGTCGGCCTGATCTATGCGCTTCCCAA
CCTGTATGGTGAGGATCCGGCTGTTCAAATCACTGGCGCGCGCGGCGTCGCCGCCAGTGAGCAAACGCTGATCCAGGTCC
AGAAAACTTTACAAGAAGAAAAAATAACCGCGAAGTCTGTGGCACTGGAAGAGGGCGCTATTCTTGCGCGCTTCGACACC
ACTGATACCCAGCTGCGCGCGCGCGAAGCGCTGCTTAACGTGCTGGGTGACAAATACGTCGTGGCGCTGAACCTTGCTCC
GGCAACCCCACGCTGGCTGGCGGCGCTCTATGCCGAGCCGATGAAGCTGGGTCTTGATCTGCGCGGCGGCGTGCACTTCC
TGATGGAAGTCGACATGGACACCGCGTTAGGCAAACTGCAGGAACAGAACATCGATAGCCTGCGCAGCGAGCTGCGCGAC
AAAGGCATTCCTTACGCGACCGTGCGTAAAGAAGACAACTACGGTCTGAGCATCGTCTTCCGCGACAGCGCGGCGCGCGA
CCAGGCTATCTCTTATCTCAGCCCTCGCCATCGCGATCTGGTTATTTCCTCTCAGGGTGACAATAGACTGAAAGCGGTGA
TGACCGATGAGCGCCTGAAAGAAGCCCGTGAGTACGCGGTTCAGCAGAACATTAATATCCTGCGTAACCGTGTGAACCAG
CTGGGCGTCGCCGAGCCGCTGGTTCAGCGTCAGGGCGCTGACCGCATCGTGGTTGAGCTGCCGGGTATCCAGGATACCGC
GCGTGCGAAGGAAATCCTTGGCGCGACCGCGACCCTCGAGTTCCGTCTGGTCAATACTAATGTGGACCAGTCCGCCGCCG
CCTCTGGCCGCGTGCCGGGCGACTCGGAAGTGAAGCAGACGCGTGAAGGCCAGCCGGTAGTGCTGTACAAGCGGGTGATC
CTGACCGGGGACCATATCACCGACTCGACCTCCAGCATGGATGAGTACAACCAGCCGCAGGTTAACATCTCGCTGGACAG
CGCGGGCGGTAACATCATGTCTAACTTCACTAAGGACAACATCGGCAAGCCGATGGCGACCCTGTTCGTGGAGTATAAAG
ACAGCGGTAAGAAAGACGCTAACGGTCGCGCTATCCTGGCGAAAGAGGAAGAGGTGATTAACATCGCCAACATCCAGTCG
CGTCTGGGTAACAGCTTCCGTATCACCGGTATCAGCAATCCGAACGAAGCGCGTCAGCTGTCGCTGCTGCTGCGTGCCGG
CGCGCTGATTGCGCCGATTCAGATCGTCGAAGAGCGGACTATCGGCCCAACCCTGGGAATGCAGAACATCAAGCAGGGTC
TGGAAGCCTGTCTGGCCGGTCTGGTGGTCTCTATCCTGTTCATGATCCTCTTCTATAAGAAGTTCGGCCTGATTGCGACC
TCGGCGCTGATTGCCAACCTGATACTGATTGTCGGCATTATGTCCCTGATCCCGGGGGCGACGCTGACCATGCCGGGCAT
CGCGGGTATCGTGTTAACCCTGGCGGTGGCGGTCGATGCTAACGTTCTGATCAACGAGCGTATCAAAGAAGAGCTGAGCA
ACGGGCGTACCGTTCAGCAGGCGATTGACGAAGGTTATCGCGGCGCGTTCAGCTCGATCTTCGACGCCAACGTGACGACG
CTTATCAAAGTGATCATCCTGTACGCGGTCGGTACCGGTGCCATTAAAGGGTTTGCGATTACCACCGGTATCGGTATCGC
GACCTCAATGTTTACCGCTATCGTCGGCACCCGTGCCATCGTGAACCTGCTGTACGGCGGCAAGCGCGTTAAAAAGCTGT
CTATCTGA

Upstream 100 bases:

>100_bases
ATACCACTGAAGTGGTTATCAAACGTGACTTCGTTGCTGCCGTTCTGCCGAAAGGCACCATGAAGGCGCTGTAATCTAAC
TTTTCCCAAAGGGAACTGCC

Downstream 100 bases:

>100_bases
GGAGTGCGTTGTGGCACAGGAATATACTGTTGAACAATTGAACCACGGCCGTAAAGTCTGGGACTTTATGCGCTGGGACT
ACTGGGCCTTCGGCATTTCA

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MLNRYPLWKYVMLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDT
TDTQLRAREALLNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRD
KGIPYATVRKEDNYGLSIVFRDSAARDQAISYLSPRHRDLVISSQGDNRLKAVMTDERLKEAREYAVQQNINILRNRVNQ
LGVAEPLVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQPVVLYKRVI
LTGDHITDSTSSMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQS
RLGNSFRITGISNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIAT
SALIANLILIVGIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANVTT
LIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVKKLSI

Sequences:

>Translated_615_residues
MLNRYPLWKYVMLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDT
TDTQLRAREALLNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRD
KGIPYATVRKEDNYGLSIVFRDSAARDQAISYLSPRHRDLVISSQGDNRLKAVMTDERLKEAREYAVQQNINILRNRVNQ
LGVAEPLVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQPVVLYKRVI
LTGDHITDSTSSMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQS
RLGNSFRITGISNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIAT
SALIANLILIVGIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANVTT
LIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVKKLSI
>Mature_615_residues
MLNRYPLWKYVMLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDT
TDTQLRAREALLNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRD
KGIPYATVRKEDNYGLSIVFRDSAARDQAISYLSPRHRDLVISSQGDNRLKAVMTDERLKEAREYAVQQNINILRNRVNQ
LGVAEPLVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQPVVLYKRVI
LTGDHITDSTSSMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQS
RLGNSFRITGISNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIAT
SALIANLILIVGIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANVTT
LIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVKKLSI

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=615, Percent_Identity=93.3333333333333, Blast_Score=1174, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 66786; Mature: 66786

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRYPLWKYVMLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
KITAKSVALEEGAILARFDTTDTQLRAREALLNVLGDKYVVALNLAPATPRWLAALYAEP
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
MKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRDKGIPYATVRKEDNYGLSIVF
HHCCCCCCCCEEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEE
RDSAARDQAISYLSPRHRDLVISSQGDNRLKAVMTDERLKEAREYAVQQNINILRNRVNQ
ECCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAEPLVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPG
CCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEEEECCCCCHHHCCCCCCC
DSEVKQTREGQPVVLYKRVILTGDHITDSTSSMDEYNQPQVNISLDSAGGNIMSNFTKDN
CHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCHHHHCCCHHC
IGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQSRLGNSFRITGISNPNEARQL
CCCCHHHEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
SLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIAT
HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALIANLILIVGIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
AIDEGYRGAFSSIFDANVTTLIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
VNLLYGGKRVKKLSI
HHHHHCCCCEEECCC
>Mature Secondary Structure
MLNRYPLWKYVMLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
KITAKSVALEEGAILARFDTTDTQLRAREALLNVLGDKYVVALNLAPATPRWLAALYAEP
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
MKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRDKGIPYATVRKEDNYGLSIVF
HHCCCCCCCCEEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEE
RDSAARDQAISYLSPRHRDLVISSQGDNRLKAVMTDERLKEAREYAVQQNINILRNRVNQ
ECCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAEPLVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPG
CCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEEEECCCCCHHHCCCCCCC
DSEVKQTREGQPVVLYKRVILTGDHITDSTSSMDEYNQPQVNISLDSAGGNIMSNFTKDN
CHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCHHHHCCCHHC
IGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQSRLGNSFRITGISNPNEARQL
CCCCHHHEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
SLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIAT
HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALIANLILIVGIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
AIDEGYRGAFSSIFDANVTTLIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
VNLLYGGKRVKKLSI
HHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]