Click here to switch to the map view.

The map label for this gene is panC [H]

Identifier: 238893119

GI number: 238893119

Start: 950645

End: 951499

Strand: Reverse

Name: panC [H]

Synonym: KP1_0967

Alternate gene names: 238893119

Gene position: 951499-950645 (Counterclockwise)

Preceding gene: 238893120

Following gene: 238893118

Centisome position: 18.13

GC content: 59.88

Gene sequence:

>855_bases
GTGCTGATTATTGAATCCGTACTGCTGCTGCGGCAGCATATCCGCCGTCTGCGTCAGGAAGGTAAGCGTATCGCGTTGGT
CCCGACGATGGGCAACCTGCATGATGGTCATATGAAGCTGGTTGATGAAGCCAAAGCCAGTGCGGACGTGGTGGTGGTCA
GTATTTTCGTCAATCCGATGCAGTTTGACCGCGTCGACGACCTGGCGCGCTACCCGCGCACCTTACAGGATGATTGCGAA
AAGCTGAACAAACGTCATGTCGACTTTGTCTTCGCGCCGACGCCGGCGGAAGTGTACCCCCAGGGTACTGAAGGCCAGAC
CTACGTCGACGTTCCGGGATTATCCACCATGCTCGAAGGCGCCAGCCGCCCGGGCCATTTCCGCGGCGTGTCGACCATCG
TCAGTAAGCTGTTCAACCTTGTTCAACCAGACGTCGCCTGCTTCGGCGAGAAAGACTTCCAGCAGTTGGCGCTGATCCGC
AAGATGGTCGCCGACATGGGCTACGACATTGAGATCATCGGCGTGCCGATCGTCCGCGCGAAAGATGGCCTGGCGCTGAG
TTCGCGTAACGGCTACCTGACCGCCGACCAGCGCAAAATCGCGCCTGGTCTGTATAAAGTGCTGAGCGCGGTGGCGGAAA
AGCTGGCCGCCGGCGATCGCCAGCTCGATGAGATCATCGCTATCGCTGAACAGGAGCTGAATGAGAAAGGCTTCCGCGCC
GACGACATTCAGATCCGCGATGCCGACACCCTGCTTGAGCTGACCGATGCCAGCCAGCGCGCGGTGATCCTGATGGCCGC
CTGGCTGGGGCAGGCTCGCCTGATCGACAACCGGATCGTCACGCTCGCTCAGTAG

Upstream 100 bases:

>100_bases
AAGCGGGCGACATCCGCGCCGCGGTGCGGCAGTATATTGCCGAAGTCGAATCCGGAGTCTATCCGGGCGAAGAACACAGT
TTCCATTAAGGAGTCTTGTT

Downstream 100 bases:

>100_bases
ACAGCGGGTAAAAATCGGGCAATACTGCCCGGGCTTTTCTCAGGGCGGGCGCCGTGTCCGCTCTGCTACATTAAGGTTGA
AGGGTAGAAGTTATGATGCG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLIIESVLLLRQHIRRLRQEGKRIALVPTMGNLHDGHMKLVDEAKASADVVVVSIFVNPMQFDRVDDLARYPRTLQDDCE
KLNKRHVDFVFAPTPAEVYPQGTEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDVACFGEKDFQQLALIR
KMVADMGYDIEIIGVPIVRAKDGLALSSRNGYLTADQRKIAPGLYKVLSAVAEKLAAGDRQLDEIIAIAEQELNEKGFRA
DDIQIRDADTLLELTDASQRAVILMAAWLGQARLIDNRIVTLAQ

Sequences:

>Translated_284_residues
MLIIESVLLLRQHIRRLRQEGKRIALVPTMGNLHDGHMKLVDEAKASADVVVVSIFVNPMQFDRVDDLARYPRTLQDDCE
KLNKRHVDFVFAPTPAEVYPQGTEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDVACFGEKDFQQLALIR
KMVADMGYDIEIIGVPIVRAKDGLALSSRNGYLTADQRKIAPGLYKVLSAVAEKLAAGDRQLDEIIAIAEQELNEKGFRA
DDIQIRDADTLLELTDASQRAVILMAAWLGQARLIDNRIVTLAQ
>Mature_284_residues
MLIIESVLLLRQHIRRLRQEGKRIALVPTMGNLHDGHMKLVDEAKASADVVVVSIFVNPMQFDRVDDLARYPRTLQDDCE
KLNKRHVDFVFAPTPAEVYPQGTEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDVACFGEKDFQQLALIR
KMVADMGYDIEIIGVPIVRAKDGLALSSRNGYLTADQRKIAPGLYKVLSAVAEKLAAGDRQLDEIIAIAEQELNEKGFRA
DDIQIRDADTLLELTDASQRAVILMAAWLGQARLIDNRIVTLAQ

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=283, Percent_Identity=85.1590106007067, Blast_Score=501, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6322046, Length=303, Percent_Identity=39.2739273927393, Blast_Score=192, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31533; Mature: 31533

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIESVLLLRQHIRRLRQEGKRIALVPTMGNLHDGHMKLVDEAKASADVVVVSIFVNPM
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEECCH
QFDRVDDLARYPRTLQDDCEKLNKRHVDFVFAPTPAEVYPQGTEGQTYVDVPGLSTMLEG
HHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHCCCCCCCCEEEECCCHHHHHHC
ASRPGHFRGVSTIVSKLFNLVQPDVACFGEKDFQQLALIRKMVADMGYDIEIIGVPIVRA
CCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
KDGLALSSRNGYLTADQRKIAPGLYKVLSAVAEKLAAGDRQLDEIIAIAEQELNEKGFRA
CCCCEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
DDIQIRDADTLLELTDASQRAVILMAAWLGQARLIDNRIVTLAQ
CCEEEECHHHHHHHCCCCCHHEEHHHHHHCCHHHHCCCEEEECC
>Mature Secondary Structure
MLIIESVLLLRQHIRRLRQEGKRIALVPTMGNLHDGHMKLVDEAKASADVVVVSIFVNPM
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEECCH
QFDRVDDLARYPRTLQDDCEKLNKRHVDFVFAPTPAEVYPQGTEGQTYVDVPGLSTMLEG
HHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHCCCCCCCCEEEECCCHHHHHHC
ASRPGHFRGVSTIVSKLFNLVQPDVACFGEKDFQQLALIRKMVADMGYDIEIIGVPIVRA
CCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
KDGLALSSRNGYLTADQRKIAPGLYKVLSAVAEKLAAGDRQLDEIIAIAEQELNEKGFRA
CCCCEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
DDIQIRDADTLLELTDASQRAVILMAAWLGQARLIDNRIVTLAQ
CCEEEECHHHHHHHCCCCCHHEEHHHHHHCCHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA