| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is gudP [H]
Identifier: 238893047
GI number: 238893047
Start: 868086
End: 869396
Strand: Reverse
Name: gudP [H]
Synonym: KP1_0884
Alternate gene names: 238893047
Gene position: 869396-868086 (Counterclockwise)
Preceding gene: 238893049
Following gene: 238893044
Centisome position: 16.56
GC content: 52.02
Gene sequence:
>1311_bases ATGAGTATGTCAAACTCTCAGGAAGTCCTCACTTCCACATCGGGGGCGAAAAAAAGAAGCCGCGTACGGATAGTTATTCT GCTGCTACTCTCCGTCGGAACGATGATCAATTATCTCGACCGTACCATCCTGGGTATTGTAGCGCCACAGTTAAGCAAAG AAATCCATATCGATCCGGCGATGATGGGTATCATCTTCTCCGCCTTCGCCTGGACTTATGCGCTGGCGCAGATCCCCGGC GGGATGTTTTTAGACCGCTTTGGCAACAAAGTGACCTATGCCCTGTCAGTTTTCTTCTGGTCGCTGTTTACCCTGCTGCA AAGTTTCACCCTCGGCCTAAAATCCCTGCTGCTTCTGCGCCTGGGACTCGGCGTCAGCGAAGCGCCCTGCTTTCCGGCCA ACAGCCGCATCGTCAGCACCTGGTTCCCTCAGCATGAGCGCGCGCGGGCAACGGCAACATATACAGTTGGTGAATATATA GGGCTGGCCGCTTTCTCGCCGCTGTTATTTTTAATTCTCGAACATCATGGCTGGAGAACGCTTTTTTTCCTCACCGGCGG ATTAGGTATTTTATTTACTTTAGTGTGGTGGCGTTTTTATCATGAACCGCATGAATCGCACACGGCTAATCAAGCGGAGC TGGAGTATATCGGCGCAAACAGCATTAACAATAAAATCCAGAACGTTCCATTTAACTGGCGTGACGCCAGACGCCTGCTG GGCTGTCGCCAGATCCTCGGCGCCAGCCTGGGTCAGTTCGCCGGCAACACCACACTGGTCTTTTTCCTGACGTGGTTTCC CAGCTACCTCGCCAACGAGCGCCATCTTCCATGGCTGCACGTCGGCTTCTTCGCCACCTGGCCCTTCCTTGCCGCCGCGA TTGGCATCCTCTTCGGCGGCTGGATCTCCGACCGGTTGTTGAAGCGAACCGGCTCCGTCAACATCAGTCGAAAGTTACCA ATAATTTCCGGTTTATTGCTGTCCAGCTGTATTATCGCGGCGAATTGGGTAAGCGCCAATAGCACCGTAATTATTATCAT GTCGGTGGCTTTTTTTGGCCAGGGGATGGTCGGTCTGGGCTGGACCTTAATTTCTGATATTACCCCGGAAAATATGGCAG GCCTCACCGGCGGCATATTTAATTTCTGTGCCAATATGGCCTCGATTATCGCACCACTGATAATTGGTGTGATTATTTCC GCCACGGGTAATTTCTTTTACGCGCTGATCTACGTCGGCCTGACGGCGCTGATTGGGGTGATTGCCTACATTTTTATCAT CGGCGACATTAAGCGTATCGAACTCAAGTAG
Upstream 100 bases:
>100_bases ACAAGGCATTGCTATTCATAGATACTACCTATAGCTCCTTGAGATATTTTTGCATATTAGAATATATGCAAAAATATTTT AAACTTTAAAGGAACTCGCT
Downstream 100 bases:
>100_bases GCCTGGTCGCCCCGGCGATGCCGGGGCGAGTAGTCAGATATCCTTCACCTTGCTGGTCAAAAACAGCGTCACCAGCGAAA TGGCCGCGATCGTCCAGTAG
Product: permease of the major facilitator superfamily
Products: NA
Alternate protein names: D-glucarate permease [H]
Number of amino acids: Translated: 436; Mature: 435
Protein sequence:
>436_residues MSMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPAMMGIIFSAFAWTYALAQIPG GMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLRLGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYI GLAAFSPLLFLILEHHGWRTLFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGGWISDRLLKRTGSVNISRKLP IISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLGWTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIIS ATGNFFYALIYVGLTALIGVIAYIFIIGDIKRIELK
Sequences:
>Translated_436_residues MSMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPAMMGIIFSAFAWTYALAQIPG GMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLRLGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYI GLAAFSPLLFLILEHHGWRTLFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGGWISDRLLKRTGSVNISRKLP IISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLGWTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIIS ATGNFFYALIYVGLTALIGVIAYIFIIGDIKRIELK >Mature_435_residues SMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPAMMGIIFSAFAWTYALAQIPGG MFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLRLGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYIG LAAFSPLLFLILEHHGWRTLFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLLG CRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGGWISDRLLKRTGSVNISRKLPI ISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLGWTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIISA TGNFFYALIYVGLTALIGVIAYIFIIGDIKRIELK
Specific function: Uptake of D-glucarate [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]
Homologues:
Organism=Homo sapiens, GI9945322, Length=389, Percent_Identity=24.6786632390745, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI21322234, Length=404, Percent_Identity=23.019801980198, Blast_Score=99, Evalue=7e-21, Organism=Homo sapiens, GI154350196, Length=406, Percent_Identity=24.1379310344828, Blast_Score=99, Evalue=1e-20, Organism=Homo sapiens, GI9966811, Length=387, Percent_Identity=24.5478036175711, Blast_Score=98, Evalue=1e-20, Organism=Homo sapiens, GI148743791, Length=390, Percent_Identity=25.3846153846154, Blast_Score=95, Evalue=1e-19, Organism=Homo sapiens, GI6912666, Length=355, Percent_Identity=24.7887323943662, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI223718438, Length=398, Percent_Identity=21.8592964824121, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI148728191, Length=330, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=4e-14, Organism=Homo sapiens, GI4885441, Length=378, Percent_Identity=24.8677248677249, Blast_Score=74, Evalue=3e-13, Organism=Homo sapiens, GI5031955, Length=255, Percent_Identity=24.7058823529412, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI154800443, Length=347, Percent_Identity=24.207492795389, Blast_Score=68, Evalue=2e-11, Organism=Escherichia coli, GI1789152, Length=439, Percent_Identity=43.7357630979499, Blast_Score=376, Evalue=1e-105, Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=42.8235294117647, Blast_Score=363, Evalue=1e-102, Organism=Escherichia coli, GI1789515, Length=442, Percent_Identity=41.4027149321267, Blast_Score=346, Evalue=2e-96, Organism=Escherichia coli, GI2367379, Length=430, Percent_Identity=30.6976744186047, Blast_Score=208, Evalue=7e-55, Organism=Escherichia coli, GI2367193, Length=390, Percent_Identity=26.1538461538462, Blast_Score=130, Evalue=1e-31, Organism=Escherichia coli, GI87082071, Length=304, Percent_Identity=23.6842105263158, Blast_Score=68, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115533554, Length=381, Percent_Identity=23.6220472440945, Blast_Score=100, Evalue=2e-21, Organism=Caenorhabditis elegans, GI115533556, Length=381, Percent_Identity=23.6220472440945, Blast_Score=100, Evalue=3e-21, Organism=Caenorhabditis elegans, GI193205400, Length=319, Percent_Identity=24.1379310344828, Blast_Score=93, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17535049, Length=429, Percent_Identity=22.8438228438228, Blast_Score=91, Evalue=1e-18, Organism=Caenorhabditis elegans, GI25141316, Length=438, Percent_Identity=24.2009132420091, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI25141341, Length=327, Percent_Identity=25.6880733944954, Blast_Score=86, Evalue=5e-17, Organism=Caenorhabditis elegans, GI25141318, Length=327, Percent_Identity=25.9938837920489, Blast_Score=86, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17552542, Length=359, Percent_Identity=24.2339832869081, Blast_Score=85, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17560030, Length=376, Percent_Identity=24.7340425531915, Blast_Score=82, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17554148, Length=309, Percent_Identity=22.9773462783171, Blast_Score=81, Evalue=1e-15, Organism=Caenorhabditis elegans, GI32565914, Length=355, Percent_Identity=23.0985915492958, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI86561091, Length=308, Percent_Identity=25.6493506493506, Blast_Score=76, Evalue=3e-14, Organism=Caenorhabditis elegans, GI32565916, Length=237, Percent_Identity=22.7848101265823, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560966, Length=336, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193208223, Length=421, Percent_Identity=22.8028503562945, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17554962, Length=325, Percent_Identity=21.5384615384615, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71997452, Length=401, Percent_Identity=19.9501246882793, Blast_Score=69, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71991448, Length=355, Percent_Identity=24.5070422535211, Blast_Score=65, Evalue=8e-11, Organism=Caenorhabditis elegans, GI71991453, Length=355, Percent_Identity=24.5070422535211, Blast_Score=65, Evalue=8e-11, Organism=Drosophila melanogaster, GI28573299, Length=389, Percent_Identity=28.2776349614396, Blast_Score=120, Evalue=2e-27, Organism=Drosophila melanogaster, GI24583789, Length=388, Percent_Identity=23.1958762886598, Blast_Score=101, Evalue=1e-21, Organism=Drosophila melanogaster, GI28573708, Length=366, Percent_Identity=24.5901639344262, Blast_Score=95, Evalue=1e-19, Organism=Drosophila melanogaster, GI28573707, Length=366, Percent_Identity=24.5901639344262, Blast_Score=95, Evalue=1e-19, Organism=Drosophila melanogaster, GI19922400, Length=354, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24654215, Length=354, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=2e-19, Organism=Drosophila melanogaster, GI24584153, Length=381, Percent_Identity=21.7847769028871, Blast_Score=92, Evalue=5e-19, Organism=Drosophila melanogaster, GI24658658, Length=437, Percent_Identity=23.7986270022883, Blast_Score=92, Evalue=6e-19, Organism=Drosophila melanogaster, GI24648416, Length=424, Percent_Identity=22.1698113207547, Blast_Score=89, Evalue=7e-18, Organism=Drosophila melanogaster, GI21356189, Length=424, Percent_Identity=22.1698113207547, Blast_Score=89, Evalue=7e-18, Organism=Drosophila melanogaster, GI24641682, Length=387, Percent_Identity=26.0981912144703, Blast_Score=87, Evalue=3e-17, Organism=Drosophila melanogaster, GI24655271, Length=415, Percent_Identity=24.578313253012, Blast_Score=85, Evalue=1e-16, Organism=Drosophila melanogaster, GI24655255, Length=389, Percent_Identity=25.1928020565553, Blast_Score=85, Evalue=1e-16, Organism=Drosophila melanogaster, GI45550460, Length=389, Percent_Identity=25.1928020565553, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI20130135, Length=415, Percent_Identity=24.578313253012, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI62484226, Length=396, Percent_Identity=25.2525252525253, Blast_Score=84, Evalue=2e-16, Organism=Drosophila melanogaster, GI221474708, Length=168, Percent_Identity=29.7619047619048, Blast_Score=82, Evalue=8e-16, Organism=Drosophila melanogaster, GI24639764, Length=440, Percent_Identity=24.7727272727273, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI19920686, Length=408, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=3e-15, Organism=Drosophila melanogaster, GI24653727, Length=360, Percent_Identity=23.6111111111111, Blast_Score=80, Evalue=3e-15, Organism=Drosophila melanogaster, GI20129235, Length=456, Percent_Identity=23.0263157894737, Blast_Score=78, Evalue=1e-14, Organism=Drosophila melanogaster, GI24658689, Length=380, Percent_Identity=25.5263157894737, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI24658674, Length=358, Percent_Identity=24.5810055865922, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI45550495, Length=362, Percent_Identity=24.3093922651934, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI45552797, Length=350, Percent_Identity=25.4285714285714, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24658666, Length=405, Percent_Identity=22.4691358024691, Blast_Score=66, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004744 - InterPro: IPR020846 - InterPro: IPR011701 - InterPro: IPR016196 [H]
Pfam domain/function: PF07690 MFS_1 [H]
EC number: NA
Molecular weight: Translated: 48177; Mature: 48046
Theoretical pI: Translated: 9.87; Mature: 9.87
Prosite motif: PS50850 MFS
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPA CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH MMGIIFSAFAWTYALAQIPGGMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLR HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYIGLAAFSPLLFLILEHHGWRT HCCCCCCCCCCCCCCCEEEECCCCCHHCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCEE LFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL EEEHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHH GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGG HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH WISDRLLKRTGSVNISRKLPIISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLG HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEHHHHCCCHHHHH WTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIISATGNFFYALIYVGLTALIGV HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH IAYIFIIGDIKRIELK HHHHHHHCCCEEEECC >Mature Secondary Structure SMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPA CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH MMGIIFSAFAWTYALAQIPGGMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLR HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYIGLAAFSPLLFLILEHHGWRT HCCCCCCCCCCCCCCCEEEECCCCCHHCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCEE LFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL EEEHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHH GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGG HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH WISDRLLKRTGSVNISRKLPIISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLG HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEHHHHCCCHHHHH WTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIISATGNFFYALIYVGLTALIGV HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH IAYIFIIGDIKRIELK HHHHHHHCCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9278503; 9772162; 10762278 [H]