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The map label for this gene is creB [H]

Identifier: 238892984

GI number: 238892984

Start: 791927

End: 792616

Strand: Direct

Name: creB [H]

Synonym: KP1_0815

Alternate gene names: 238892984

Gene position: 791927-792616 (Clockwise)

Preceding gene: 238892983

Following gene: 238892985

Centisome position: 15.09

GC content: 62.03

Gene sequence:

>690_bases
ATGCAGCAGCCACGGATTTGGTTAGTTGAGGATGAACAGAGTATCGCTGATACCCTGGTTTACATGCTGCAGCAGGAGGG
CTTCCAGGTCAGCGTCTTTGGCCGCGGTTTGCCCGCGCTGGAGGCGGCGGCGCATCAGGCGCCAGATGTCGCCATCCTCG
ACGTCGGCTTGCCGGATATCAGCGGCTTCGAGCTCTGTCGGCGTCTGCTGACGCGTTATCCGGCGCTGCCGGTGCTGTTT
TTGACGGCGCGTAGCGACGAGGTCGATAAGCTGCTGGGGCTGGAAATCGGCGCTGACGATTACATCGCCAAGCCGTTTTC
ACCACGCGAAGTCTGCGCGCGGGTGCGAACCGTGCTGCGGCGGCTGCAGAAGTTTGCCGCGCCATCGCCGGTGGTACGCG
TCGGCGAGTTTGTGCTCGATGAGCAGGCGGCGGCGATCAGCTGGTTCGGCCAGCCGCTGAATCTGACGCGCTACGAATTT
CTGCTGCTGAAAACCCTGCTTCACGCGCCCGGTCGCGTCTTCTCCCGTCAGCAGCTGATGGAGCTGGTGTGGATCGATGC
CTGGGAAAGCCTCGACCGTACCGTCGATACCCATATCAAAACCCTGCGCGCTAAGCTGCGGGCTGTGAATCCTGAAAAGG
CGCCAATCAATACCCATCGCGGTATGGGCTACAGCCTGGGGCGCGGCTGA

Upstream 100 bases:

>100_bases
GGTCTATCTGACCTACTCGGATAAAGTGGTTGATGGCTCGCCGAAGAACGCCATCAGCGCCGTGCCGATCATGCCATGGA
ATAAATAAACGGGAGCGCGC

Downstream 100 bases:

>100_bases
TGCGCATCGGCATGCGCCTGCTGCTGGGCTATTTTCTTATCGTCGCGATCGCCGCGTGGTTTGTGCTGTCGATCTTTGTC
CAGGAAGTGAAGCCGGGCGT

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MQQPRIWLVEDEQSIADTLVYMLQQEGFQVSVFGRGLPALEAAAHQAPDVAILDVGLPDISGFELCRRLLTRYPALPVLF
LTARSDEVDKLLGLEIGADDYIAKPFSPREVCARVRTVLRRLQKFAAPSPVVRVGEFVLDEQAAAISWFGQPLNLTRYEF
LLLKTLLHAPGRVFSRQQLMELVWIDAWESLDRTVDTHIKTLRAKLRAVNPEKAPINTHRGMGYSLGRG

Sequences:

>Translated_229_residues
MQQPRIWLVEDEQSIADTLVYMLQQEGFQVSVFGRGLPALEAAAHQAPDVAILDVGLPDISGFELCRRLLTRYPALPVLF
LTARSDEVDKLLGLEIGADDYIAKPFSPREVCARVRTVLRRLQKFAAPSPVVRVGEFVLDEQAAAISWFGQPLNLTRYEF
LLLKTLLHAPGRVFSRQQLMELVWIDAWESLDRTVDTHIKTLRAKLRAVNPEKAPINTHRGMGYSLGRG
>Mature_229_residues
MQQPRIWLVEDEQSIADTLVYMLQQEGFQVSVFGRGLPALEAAAHQAPDVAILDVGLPDISGFELCRRLLTRYPALPVLF
LTARSDEVDKLLGLEIGADDYIAKPFSPREVCARVRTVLRRLQKFAAPSPVVRVGEFVLDEQAAAISWFGQPLNLTRYEF
LLLKTLLHAPGRVFSRQQLMELVWIDAWESLDRTVDTHIKTLRAKLRAVNPEKAPINTHRGMGYSLGRG

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=77.4336283185841, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=43.6123348017621, Blast_Score=180, Evalue=8e-47,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=38.3928571428571, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=34.6666666666667, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=38.2882882882883, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.6846846846847, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=34.6491228070175, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35.4545454545455, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=36.7256637168142, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=36.322869955157, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=34.1991341991342, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.2342342342342, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.6943231441048, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=34.3511450381679, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=28.7878787878788, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25775; Mature: 25775

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPRIWLVEDEQSIADTLVYMLQQEGFQVSVFGRGLPALEAAAHQAPDVAILDVGLPDI
CCCCCEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCCCC
SGFELCRRLLTRYPALPVLFLTARSDEVDKLLGLEIGADDYIAKPFSPREVCARVRTVLR
CHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCEECCCCHHCCCCCHHHHHHHHHHHHH
RLQKFAAPSPVVRVGEFVLDEQAAAISWFGQPLNLTRYEFLLLKTLLHAPGRVFSRQQLM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
ELVWIDAWESLDRTVDTHIKTLRAKLRAVNPEKAPINTHRGMGYSLGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQQPRIWLVEDEQSIADTLVYMLQQEGFQVSVFGRGLPALEAAAHQAPDVAILDVGLPDI
CCCCCEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCCCC
SGFELCRRLLTRYPALPVLFLTARSDEVDKLLGLEIGADDYIAKPFSPREVCARVRTVLR
CHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCEECCCCHHCCCCCHHHHHHHHHHHHH
RLQKFAAPSPVVRVGEFVLDEQAAAISWFGQPLNLTRYEFLLLKTLLHAPGRVFSRQQLM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
ELVWIDAWESLDRTVDTHIKTLRAKLRAVNPEKAPINTHRGMGYSLGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]